SyedAfzalHussainMD

PubMed

• 66 citations
  Quality of Life After Bladder Cancer: A Cross-sectional Survey of Patient-reported Outcomes.
  James W.F. Catto, Amy Downing, Samantha J Mason, Penny Wright, Kate Absolom, Sarah Bottomley, Luke Hounsome, Syed A. Hussain, Mohini Varughese, Caroline Raw, Phil Kell...> ;European Urology. 2021 May 1
• 60 citations
  Hypofractionated radiotherapy in locally advanced bladder cancer: an individual patient data meta-analysis of the BC2001 and BCON trials
  Ananya Choudhury, Nuria Porta, Emma Hall, Yee Pei Song, Ruth Owen, Ranald I Mackay, Catharine M L West, Rebecca Lewis, Syed A. Hussain, Nicholas D. James, Robert Hudda...> ;The Lancet. Oncology. 2021 Feb 1
• 18 citations
  Outcomes in Patients with Muscle-invasive Bladder Cancer Treated with Neoadjuvant Chemotherapy Followed by (Chemo)radiotherapy in the BC2001 Trial
  Syed A. Hussain, Nuria Porta, Emma Hall, Abdulazeez Salawu, Rebecca Lewis, Thiagarajan Sreenivasan, Jan Wallace, Malcolm Crundwell, Peter Jenkins, Jean Tremlett, Rober...> ;European Urology. 2021 Feb 1
• 14 citations
  Phase I Trial of DNA Methyltransferase Inhibitor Guadecitabine Combined with Cisplatin and Gemcitabine for Solid Malignancies Including Urothelial Carcinoma (SPIRE)
  Simon J. Crabb, Sarah Danson, James W.F. Catto, Syed A. Hussain, Danna Chan, Denise Dunkley, Nichola Downs, Ellice Marwood, Laura Day, Geoff N Saunders, Michelle Light...> ;Clinical Cancer Research. 2021 Jan 20
• 256 citations
  Durvalumab alone and durvalumab plus tremelimumab versus chemotherapy in previously untreated patients with unresectable, locally advanced or metastatic urothelial car...
  Thomas Powles, Michiel S. van der Heijden, Daniel Castellano, Matthew D. Galsky, Yohann Loriot, Daniel P. Petrylak, Osamu Ogawa, Se Hoon Park, Jae-Lyun Lee, Ugo De Gio...> ;The Lancet. Oncology. 2020 Dec 1
• 8 citations
  Incidence, Patterns, and Outcomes with Adjuvant Chemotherapy for Residual Disease After Neoadjuvant Chemotherapy in Muscle-invasive Urinary Tract Cancers.
  Nieves Martinez Chanza, Lillian Werner, Elizabeth R. Plimack, Evan Y. Yu, Ajjai Alva, Simon J. Crabb, Thomas Powles, Jonathan E. Rosenberg, Jack Baniel, Ulka N. Vaisha...> ;European Urology Oncology. 2020 Oct 1
• 11 citations
  CD40L membrane retention enhances the immunostimulatory effects of CD40 ligation
  Taha Elmetwali, Asmaa Salman, Wenbin Wei, Syed A. Hussain, Lawrence S. Young, Daniel H. Palmer> ;Scientific Reports. 2020 Jan 15
• 37 citations
  Safe Use of Immune Checkpoint Inhibitors in the Multidisciplinary Management of Urological Cancer: The European Association of Urology Position in 2019.
  Marc-Oliver Grimm, Axel Bex, Maria De Santis, Börje Ljungberg, James W.F. Catto, Morgan Rouprêt, Syed A. Hussain, Joaquim Bellmunt, Thomas Powles, Manfred P. Wirth, He...> ;European Urology. 2019 Sep 1
• 3 citations
  Vinflunine in the treatment of relapsed metastatic urothelial cancer: A systematic review and meta-analysis of real-world series.
  Aristotelis Bamias, Axel Hegele, Jacques Medioni, Daniel Castellano, Laura Doni, Rodolfo Passalacqua, Flora Zagouri, Kimon Tzannis, Syed A. Hussain, Anders Ullén> ;Critical Reviews in Oncology/hematology. 2019 May 21
• Corrigendum re: "Atezolizumab in Platinum-treated Locally Advanced or Metastatic Urothelial Carcinoma: Outcomes by Prior Number of Regimens" [Eur Urol 2018;73:462-8].
  Jose Luis Perez-Gracia, Yohann Loriot, Jonathan E. Rosenberg, Thomas Powles, Andrea Necchi, Syed A. Hussain, Rafael Morales-Barrera, Margitta Retz, Günter Niegisch, Ig...> ;European Urology. 2019 Mar 1
• 2 citations
  Venous Thromboembolism Risk in Patients With Locoregional Urothelial Tract Tumors.
  Jorge Ramos, Jonathan Wingate, Roman Gulati, Elizabeth R. Plimack, Lauren C. Harshman, Thomas Powles, Simon J. Crabb, Guenter Niegisch, Joaquim Bellmunt, Sylvain Ladoi...> ;Clinical Genitourinary Cancer. 2017 Aug 24
• 14 citations
  Gene expression profiling in bladder cancer identifies potential therapeutic targets.
  Syed A. Hussain, Daniel H. Palmer, Wing Kin Syn, Joseph J. Sacco, Richard M.D. Greensmith, Taha Elmetwali, Vijay Aachi, Bryony H. Lloyd, Puthen V. Jithesh, John R. Arr...> ;International Journal of Oncology. 2017 Apr 1
• 5 citations
  The predictive and prognostic value of tumour necrosis in muscle invasive bladder cancer patients receiving radiotherapy with or without chemotherapy in the BC2001 tri...
  Ananya Choudhury, Catharine M L West, Nuria Porta, Emma Hall, Helen Denley, Carey Hendron, Rebecca Lewis, Syed A. Hussain, Robert Huddart, Nicholas D. James> ;British Journal of Cancer. 2017 Jan 26
• 124 citations
  Phase III, Double-Blind, Randomized Trial That Compared Maintenance Lapatinib Versus Placebo After First-Line Chemotherapy in Patients With Human Epidermal Growth Fact...
  Thomas Powles, Robert Huddart, Tony Elliott, Shah-Jalal Sarker, Charlotte Ackerman, Robert Jones, Syed A. Hussain, Simon J. Crabb, Satinder Jagdev, John D. Chester, Se...> ;Journal of Clinical Oncology. 2017 Jan 1
• 928 citations
  Atezolizumab versus chemotherapy in patients with platinum-treated locally advanced or metastatic urothelial carcinoma (IMvigor211): a multicentre, open-label, phase 3...
  Thomas Powles, Ignacio Duran, Michiel S. van der Heijden, Yohann Loriot, Nicholas J. Vogelzang, Ugo De Giorgi, Stéphane Oudard, Margitta Retz, Daniel Castellano, Arist...> ;Lancet. 2017 Dec 18
• 10 citations
  Cisplatin- Versus Non–Cisplatin-based First-Line Chemotherapy for Advanced Urothelial Carcinoma Previously Treated With Perioperative Cisplatin
  Jennifer A. Locke, Gregory R. Pond, Guru Sonpavde, Andrea Necchi, Patrizia Giannatempo, Ravi Kumar Paluri, Guenter Niegisch, Peter Albers, Carlo Buonerba, Giuseppe Di ...> ;Clinical Genitourinary Cancer. 2016 Aug 1
• 77 citations
  A Randomised Phase 2 Study of AZD2014 Versus Everolimus in Patients with VEGF-Refractory Metastatic Clear Cell Renal Cancer.
  Thomas Powles, Matthew Wheater, O.S. Din, T. Geldart, Ekaterini Boleti, Andrew Stockdale, Santhanam Sundar, Angus Robinson, Imtiaz Ahmed, Akhila Wimalasingham, Wendy B...> ;European Urology. 2016 Mar 1
• 62 citations
  Fatty acid activated PPARγ promotes tumorigenicity of prostate cancer cells by up regulating VEGF via PPAR responsive elements of the promoter.
  Farzad Seyed Forootan, Shiva S. Forootan, Xiaojun Gou, Jin Yang, Bichong Liu, Danqing Chen, Majed Saad Al Fayi, Waseem Al-Jameel, Philip S. Rudland, Syed A. Hussain, Y...> ;Oncotarget. 2016 Jan 22
• 139 citations
  Comparative effectiveness of gemcitabine plus cisplatin versus methotrexate, vinblastine, doxorubicin, plus cisplatin as neoadjuvant therapy for muscle-invasive bladde...
  Matthew D. Galsky, Sumanta K. Pal, Simon Chowdhury, Lauren C. Harshman, Simon J. Crabb, Yu-Ning Wong, Evan Y. Yu, Thomas Powles, Erin Moshier, Sylvain Ladoire, Syed A....> ;Cancer. 2015 Aug 1
• 9 citations
  The international normalized ratio does not reflect bleeding risk in esophageal variceal hemorrhage.
  Tammy T. Hshieh, Aung Kaung, Syed A. Hussain, Michael P. Curry, Vinay Sundaram> ;Saudi Journal of Gastroenterology. 2015 Jul 1
• 14 citations
  Cisplatin-based first-line therapy for advanced urothelial carcinoma after previous perioperative cisplatin-based therapy
  Andrea Necchi, Gregory R. Pond, Patrizia Giannatempo, Giuseppe Di Lorenzo, Bernhard J. Eigl, Jenn Locke, Sumanta K. Pal, Neeraj Agarwal, Austin Poole, Ulka N. Vaishamp...> ;Clinical Genitourinary Cancer. 2015 Apr 1
• 9 citations
  The IFNγ‐PKR Pathway in the Prefrontal Cortex Reactions to Chronic Excessive Alcohol Use
  Jeremy W. Duncan, Syed A. Hussain, Gang Chen, Jia Luo, Channing Mclaurin, Warren L. May, Grazyna Rajkowska, Xiao-Ming Ou, Craig A. Stockmeier, Jun Ming Wang> ;Alcoholism, Clinical and Experimental Research. 2015 Mar 1
• 72 citations
  The Nrf2 transcription factor contributes to resistance to cisplatin in bladder cancer.
  Annette Hayden, James Douglas, Matthew Sommerlad, Lawrence P. Andrews, Katherine Gould, Syed A. Hussain, Gareth J. Thomas, Graham Packham, Simon J. Crabb> ;Urologic Oncology. 2014 Aug 1
• 78 citations
  Reduced connexin 43 immunolabeling in the orbitofrontal cortex in alcohol dependence and depression.
  Jose Javier Miguel-Hidalgo, Barbara A. Wilson, Syed A. Hussain, Ashish Meshram, Grazyna Rajkowska, Craig A. Stockmeier> ;Journal of Psychiatric Research. 2014 Aug 1
• 174 citations
  The Detection of Hepatocellular Carcinoma Using a Prospectively Developed and Validated Model Based on Serological Biomarkers
  Philip J. Johnson, Sarah Pirrie, Trevor Cox, Sarah Berhane, M Teng, Daniel H. Palmer, Janet Morse, Diana Hull, G.L. Patman, Chiaki Kagebayashi, Syed A. Hussain, Janine...> ;Cancer Epidemiology, Biomarkers & Prevention. 2014 Jan 1
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