Tai-HwangMichaelFanMDPhD

Echocardiography, Non-Invasive Cardiology, Cardiac Critical Care

Professor of Medicine, University of Tennessee Health Science Center Director of Echocardiography Laboratory, Memphis VA Medical Center

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Office
Memphis VAMC
1030 Jefferson Avenue
Memphis, TN 38104
Phone+1 901-523-8990
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Education & Training

University of RochesterFellowship, Cardiovascular Disease, 1991 - 1996
University of RochesterResidency, Internal Medicine, 1989 - 1991
Jacobs School of Medicine and Biomedical Sciences at the University at BuffaloClass of 1989

Certifications & Licensure

TN State Medical License 2012 - 2025
GA State Medical License 2011 - 2024
HI State Medical License 2016 - 2022
AL State Medical License 1996 - 2021
NY State Medical License 1991 - 1997
American Board of Internal Medicine Cardiovascular Disease

Awards, Honors, & Recognition

Fellow (FACC) American College of Cardiology

Publications & Presentations

PubMed

7 citations
A Low-Sodium Diet Boosts Ang (1-7) Production and NO-cGMP Bioavailability to Reduce Edema and Enhance Survival in Experimental Heart Failure.
Ranjana Tripathi, Ryan D. Sullivan, Tai-Hwang M. Fan, Radhika M. Mehta, Inna P. Gladysheva, Guy L. Reed> ;International Journal of Molecular Sciences. 2021 Apr 14
4 citations
In Experimental Dilated Cardiomyopathy Heart Failure and Survival Are Adversely Affected by a Lack of Sexual Interactions
Ranjana Tripathi, Ryan D. Sullivan, Tai-Hwang M. Fan, Radhika M. Mehta, Inna P. Gladysheva, Guy L. Reed> ;International Journal of Molecular Sciences. 2020 Jul 30
15 citations
Corin Overexpression Reduces Myocardial Infarct Size and Modulates Cardiomyocyte Apoptotic Cell Death.
Ryan D. Sullivan, Aiilyan K. Houng, Inna P. Gladysheva, Tai-Hwang M. Fan, Ranjana Tripathi, Guy L. Reed, Dong Wang> ;International Journal of Molecular Sciences. 2020 May 14
21 citations
Cardiac-Specific Overexpression of Catalytically Inactive Corin Reduces Edema, Contractile Dysfunction, and Death in Mice with Dilated Cardiomyopathy
Ranjana Tripathi, Ryan D. Sullivan, Tai-Hwang M. Fan, Aiilyan K. Houng, Radhika M. Mehta, Guy L. Reed, Inna P. Gladysheva> ;International Journal of Molecular Sciences. 2019 Dec 27
8 citations
Increases in plasma corin levels following experimental myocardial infarction reflect the severity of ischemic injury.
Dong Wang, Inna P. Gladysheva, Ryan D. Sullivan, Tai-Hwang M. Fan, Radhika M. Mehta, Ranjana Tripathi, Yao Sun, Guy L. Reed> ;Plos One. 2018 Sep 7
53 citations
Device Closure Versus Medical Therapy Alone for Patent Foramen Ovale in Patients With Cryptogenic Stroke: A Systematic Review and Meta-analysis.
Rahman Shah, Mannu Nayyar, Ion S. Jovin, Abdul Rashid, Beatrix Ramos Bondy, Tai-Hwang M. Fan, Michael P. Flaherty, Sunil V. Rao> ;Annals of Internal Medicine. 2018 Mar 6
18 citations
Enhanced heart failure, mortality and renin activation in female mice with experimental dilated cardiomyopathy.
Ranjana Tripathi, Ryan D. Sullivan, Tai-Hwang M. Fan, Dong Wang, Yao Sun, Guy L. Reed, Inna P. Gladysheva> ;Plos One. 2017 Dec 14
22 citations
Meta-Analysis of the Relative Efficacy and Safety of Oral P2Y12 Inhibitors in Patients With Acute Coronary Syndrome
Rahman Shah, Abdul Rashid, Inyong Hwang, Tai-Hwang M. Fan, Rami N. Khouzam, Guy L. Reed> ;The American Journal of Cardiology. 2017 Jun 1
3 citations
A Patient with Metastatic Small-Cell Lung Cancer and Giant Right Ventricular Mass
Rahman Shah, Elizabeth John, Tai-Hwang M. Fan, Genina Ruff, M. Rehan Khan, Lee C. Holt> ;Echocardiography. 2016 Mar 1
35 citations
Depressed Corin Levels Indicate Early Systolic Dysfunction Before Increases of Atrial Natriuretic Peptide/B-Type Natriuretic Peptide and Heart Failure Development
Ranjana Tripathi, Dong Wang, Ryan D. Sullivan, Tai-Hwang M. Fan, Inna P. Gladysheva, Guy L. Reed> ;Hypertension. 2016 Feb 1
7 citations
Cocaine-Induced Acute Aortic Dissection
Rahman Shah, Chalak Berzingi, Tai-Hwang M. Fan, Raza Askari, M. Rehan Khan> ;The Journal of Emergency Medicine. 2015 Sep 1
An 81-year-old man with an abnormal right-sided heart shadow on chest radiograph.
Rahman Shah, M. Rehan Khan, Tai-Hwang M. Fan, Genina Ruff, Kodangudi B. Ramanathan> ;Chest. 2015 Feb 1
39 citations
Atrial natriuretic peptide affects cardiac remodeling, function, heart failure, and survival in a mouse model of dilated cardiomyopathy.
Dong Wang, Inna P. Gladysheva, Tai-Hwang M. Fan, Ryan D. Sullivan, Aiilyan K. Houng, Guy L. Reed> ;Hypertension. 2014 Mar 1
Corin overexpression improves cardiac function, heart failure, and survival in mice with dilated cardiomyopathy.
Gladysheva, I. P.,Wang, D.,McNamee, R. A.,Houng, A. K.,Mohamad, A. A.,Fan, T. M.,Reed, G. L.> ;Hypertension. 2013 Feb
Uncoupled cardiac nitric oxide synthase mediates diastolic dysfunction.
Silberman, G.A., Fan, T.M., Liu, H., Jiao, Z., Xiao, H.D., Lovelock, J.D., Boulden, B.M., Widder, J., Fredd, S., Bernstein, K.E., Wolska, B.M., Dikalov, S., Harrison, ...> ;Circulation. 2010 Feb 2
127 citations
The role of NADPH oxidase in chronic intermittent hypoxia-induced pulmonary hypertension in mice
R. Nisbet, A. S. Graves, Dean J. Kleinhenz, Heidi L. Rupnow, Alana L. Reed, Tai Hwang M. Fan, Patrick O. Mitchell, Roy L. Sutliff, C. Michael Hart> ;American Journal of Respiratory Cell and Molecular Biology. 2009 May 1
A tissue engineering approach to progenitor cell delivery results in significant cell engraftment and improved myocardial remodeling.
Simpson, D., Liu, H., Fan, T.M., Nerem, R., Dudley, S.C.> ;Stem Cells. 2007 Sep
24 citations
ACE inhibition improves cardiac NE uptake and attenuates sympathetic nerve terminal abnormalities in heart failure.
Hiroya Kawai, Tai-Hwang M. Fan, Erdan Dong, Rizwan A. Siddiqui, Akito Yatani, Suzanne Y. Stevens, Chang-seng Liang> ;The American Journal of Physiology. 1999 Oct 1
9 citations
Elevated myocardial interstitial norepinephrine concentration contributes to the regulation of Na+,K+-ATPase in heart failure
Ling Ping Lai, Tai-Hwang M. Fan, Joseph M. Delehanty, Akito Yatani, Chang-seng Liang> ;European Journal of Pharmacology. 1996 Aug 15
15 citations
Reductions of myocardial Na-K-ATPase activity and ouabain binding sites in heart failure : prevention by nadolol
Tai-Hwang M. Fan, R. P. Frantz, H. Elam, S. Sakamoto, N. Imai, Chang-seng Liang> ;The American Journal of Physiology. 1993 Dec 1
4 citations
Both cell surface and internalized β-adrenoceptors are reduced in the failing myocardium
J. Thompson Sullebarger, Tai-Hwang M. Fan, Fernando Torres, Chang-seng Liang> ;European Journal of Pharmacology. 1991 Nov 26
29 citations
Chronic beta-adrenoceptor blockade prevents the development of beta-adrenergic subsensitivity in experimental right-sided congestive heart failure in dogs.
Chang-seng Liang, R. P. Frantz, M. Suematsu, S. Sakamoto, J. T. Sullebarger, Tai-Hwang M. Fan, L. Guthinger> ;Circulation. 1991 Jul 1
65 citations
Alterations in cardiac β-adrenoceptor responsiveness and adenylate cyclase system by congestive heart failure in dogs
Tai-Hwang M. Fan, Chang-seng Liang, Seinosuke Kawashima, Shailesh P. Banerjee> ;European Journal of Pharmacology. 1987 Aug 11
12 citations
Renin-Angiotensin Activation and Oxidative Stress in Early Heart Failure with Preserved Ejection Fraction.
Smita I. Negi, Euy Myoung Jeong, Irfan Shukrullah, Emir Veleder, Dean P. Jones, Tai Hwang M. Fan, Sudhahar Varadarajan, Sergei M. Danilov, Tohru Fukai, Samuel C. Dudley> ;Biomed Research International. 2015 Oct 4
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Professional Memberships

American College of Cardiology - ACC
Fellow
American Society of Echocardiography - ASE
Member

Other Languages

Chinese (Mandarin)

Hospital Affiliations

Lt. Col. Luke Weathers, Jr. VA Medical CenterMemphis, Tennessee
University of Tennessee Health Science CenterMemphis, Tennessee
Baptist Memorial Hospital - MemphisMemphis, Tennessee