TheodorePravinchandraAbrahamMDFACC, FASE

Echocardiography, Non-Invasive Cardiology

Professor of Medicine and Radiology, Johns Hopkins University School of Medicine; Director, Johns Hopkins Hypertrophic Cardiomyopathy Center of Excellence; Associate Dean for Research - National Capital Region

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Office
University of California, San Francisco
505 Parnassus Ave
San Francisco, CA 94127
Phone+1 415-353-9156

Fax+1 415-353-8687
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Education & Training

University of Texas Southwestern Medical CenterFellowship, Cardiovascular Disease, 1996 - 1999
Wake Forest University School of MedicineResidency, Internal Medicine, 1992 - 1995
Goa Medical CollegeClass of 1987

Certifications & Licensure

CA State Medical License 2017 - 2026
MD State Medical License 2003 - 2018
MN State Medical License 1999 - 2009
TX State Medical License 1998 - 1999
NC State Medical License 1995 - 1998
American Board of Internal Medicine Cardiovascular Disease

Awards, Honors, & Recognition

CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2013-2014
Fellow (FACC) American College of Cardiology

Clinical Trials

HCMR - Novel Markers of Prognosis in Hypertrophic Cardiomyopathy Start of enrollment: 2014 Apr 01
Active, not recruiting
Dose-finding Study to Evaluate the Safety, Tolerability, PK, and PD of CK-3773274 in Adults With HCM Start of enrollment: 2020 Jan 10
Completed
Phase 2
Roles: Contact

Publications & Presentations

PubMed

Efficacy and Safety of aficamten in Symptomatic Non-Obstructive Hypertrophic Cardiomyopathy: Results From the REDWOOD-HCM Trial, Cohort 4.
Ahmad Masri, Mark V Sherrid, Theodore P Abraham, Lubna Choudhury, Pablo Garcia-Pavia, Christopher M Kramer, Roberto Barriales-Villa, Anjali T Owens, Florian Rader, She...> ;Journal of Cardiac Failure. 2024 Mar 15
Role of Imaging in the Diagnosis, Evaluation, and Management of Hypertrophic Cardiomyopathy.
Abraham, M., Abraham, T.> ;The American Journal of Cardiology. 2024 Feb 1
Differences in Health-Related Quality of Life among Patients with Heart Failure.
Ioannis Ventoulis, Vasileios Kamperidis, Maria Roselle Abraham, Theodore Abraham, Antonios Boultadakis, Efthymios Tsioukras, Aikaterini Katsiana, Konstantinos Georgiou...> ;Medicina. 2024 Jan 6
4 citations
Mavacamten Treatment for Symptomatic Obstructive Hypertrophic Cardiomyopathy: Interim Results From the MAVA-LTE Study, EXPLORER-LTE Cohort.
Rader, F., Oręziak, A., Choudhury, L., Saberi, S., Fermin, D., Wheeler, M., Abraham, T., Garcia-Pavia, P., Zwas, D., Masri, A., Owens, A., Hegde, S., Seidler, T., Fox,...> ;JACC. Heart Failure. 2024 Jan 1
Frequent Premature Atrial Contractions Lead to Adverse Atrial Remodeling and Atrial Fibrillation in a Swine Model.
Satoshi Higuchi, Aleksandr Voskoboinik, Adam Lee, Jeffrey Olgin, Ayla Arbil, Junaid Afzal, Gregory M Marcus, Carol Stillson, Dwight Bibby, Theodore Abraham, Emily Wils...> ;Circulation. 2024 Feb 6
1 citations
Exercise Capacity in Patients With Obstructive Hypertrophic Cardiomyopathy: SEQUOIA-HCM Baseline Characteristics and Study Design.
Caroline J Coats, Martin S Maron, Theodore P Abraham, Iacopo Olivotto, Matthew M Y Lee, Michael Arad, Nuno Cardim, Chang-Sheng Ma, Lubna Choudhury, Hans-Dirk Düngen, P...> ;JACC. Heart Failure. 2024 Jan 1
Mavacamten for Obstructive Hypertrophic Cardiomyopathy With or Without Hypertension: Post-Hoc Analysis of the EXPLORER-HCM Trial.
Andrew Wang, John A Spertus, Daniel M Wojdyla, Theodore P Abraham, Ester Kim Nilles, Anjali Tiku Owens, Sara Saberi, Sharon Cresci, Amy Sehnert, Neal K Lakdawala> ;JACC. Heart Failure. 2024 Mar 1
5 citations
Mavacamten: a first-in-class myosin inhibitor for obstructive hypertrophic cardiomyopathy.
Eugene Braunwald, Sara Saberi, Theodore P Abraham, Perry M Elliott, Iacopo Olivotto> ;European Heart Journal. 2023 Nov 21
Patient-Level Artificial Intelligence-Enhanced Electrocardiography in Hypertrophic Cardiomyopathy: Longitudinal Treatment and Clinical Biomarker Correlations.
Siontis, K., Abreau, S., Attia, Z., Barrios, J., Dewland, T., Agarwal, P., Balasubramanyam, A., Li, Y., Lester, S., Masri, A., Wang, A., Sehnert, A., Edelberg, J., Abr...> ;JACC. Advances. 2023 Oct 1
Energetics of Cardiac Blood Flow in Hypertrophic Cardiomyopathy through Individualized Computational Modeling.
Owen Baenen, Angie Carolina Carreño-Martínez, Theodore P Abraham, Sandra Rugonyi> ;Journal of Cardiovascular Development and Disease. 2023 Sep 27
Systolic blood pressure ≤110 mm Hg is associated with severe coronary microvascular ischemia and higher risk for ventricular arrhythmias in hypertrophic cardiomyopathy.
Dai-Yin Lu, Hulya Yalcin, Fatih Yalcin, Sanjay Sivalokanathan, Gabriela V Greenland, Ioannis Ventoulis, Styliani Vakrou, Miguel Hernandez Pampaloni, Stefan L Zimmerman...> ;Heart Rhythm O2. 2023 Sep 1
1 citations
Geomeric and functional aspects in hypertension and takotsubo: importance of basal septal hypertrophy.
Fatih Yalçin, Boran Çağatay, Nagehan Küçükler, Theodore P Abraham> ;European Journal of Preventive Cardiology. 2023 Dec 21
6 citations
Aficamten for Drug-Refractory Severe Obstructive Hypertrophic Cardiomyopathy in Patients Receiving Disopyramide: REDWOOD-HCM Cohort 3.
Anjali T Owens, Ahmad Masri, Theodore P Abraham, Lubna Choudhury, Florian Rader, John D Symanski, Aslan T Turer, Timothy C Wong, Albree Tower-Rader, Caroline J Coats, ...> ;Journal of Cardiac Failure. 2023 Nov 1
1 citations
The (Heart and) Soul of a Human Creation: Designing Echocardiography for the Big Data Age.
Rima Arnaout, Rebecca T Hahn, Judy W Hung, Pei-Ni Jone, Steven J Lester, Stephen H Little, G Burkhard Mackensen, Vera Rigolin, Vandana Sachdev, Muhamed Saric, Partho P...> ;Journal of the American Society of Echocardiography. 2023 Jul 1
2 citations
A Practical Approach to Echocardiographic Imaging in Patients With Hypertrophic Cardiomyopathy.
Carol C Mitchell, Cody Frye, Madeline Jankowski, John Symanski, Steven J Lester, Anna Woo, Yvonne Gilliland, Andreea Dragulescu, Theodore Abraham, Milind Desai, Matthe...> ;Journal of the American Society of Echocardiography. 2023 Sep 1
1 citations
A call to consider an aortic stenosis screening program.
Ju Young Bae, Arzhang Fallahi, Wayne Miller, Martin B Leon, Theodore P Abraham, Sripal Bangalore, David H Hsi> ;Trends in Cardiovascular Medicine. 2023 Apr 25
Computational analysis of ventricular mechanics in hypertrophic cardiomyopathy patients.
Joy Mojumder, Lei Fan, Thuy Nguyen, Kenneth S Campbell, Jonathan F Wenk, Julius M Guccione, Theodore Abraham, Lik Chuan Lee> ;Scientific Reports. 2023 Jan 18
2 citations
Acute liver injury in COVID-19 patients hospitalized in the intensive care unit: Narrative review.
Effie Polyzogopoulou, Pinelopi Amoiridou, Theodore P Abraham, Ioannis Ventoulis> ;World Journal of Gastroenterology. 2022 Dec 21
7 citations
Premature Ventricular Contractions Are Presaged by a Mechanically Abnormal Sinus Beat.
Christina Alhede, Satoshi Higuchi, Alexios Hadjis, Dwight Bibby, Theodore Abraham, Nelson B Schiller, Edward P Gerstenfeld> ;JACC. Clinical Electrophysiology. 2022 Aug 1
1 citations
It is time to assess left ventricular segmental remodelling in aortic stenosis.
Fatih Yalçin, Maria Roselle Abraham, Theodore P Abraham> ;European Heart Journal. Cardiovascular Imaging. 2022 Jul 21
32 citations
Recommendations for Multimodality Cardiovascular Imaging of Patients with Hypertrophic Cardiomyopathy: An Update from the American Society of Echocardiography, in Coll...
Sherif F Nagueh, Dermot Phelan, Theodore Abraham, Alicia Armour, Milind Y Desai, Andreea Dragulescu, Yvonne Gilliland, Steven J Lester, Yasdet Maldonado, Saidi Mohiddi...> ;Journal of the American Society of Echocardiography. 2022 Jun 1
2 citations
Sex differences in clinical outcomes for obstructive hypertrophic cardiomyopathy in the USA: a retrospective observational study of administrative claims data.
Michael Butzner, Douglas Leslie, Yendelela Cuffee, Christopher S Hollenbeak, Christopher Sciamanna, Theodore P Abraham> ;BMJ Open. 2022 Mar 9
3 citations
Basal septal hypertrophy: extremely sensitive region to variety of stress stimuli and stressed heart morphology.
Fatih Yalçin, Roselle Abraham, Theodore P Abraham> ;Journal of Hypertension. 2022 Mar 1
44 citations
Effect of Mavacamten on Echocardiographic Features in Symptomatic Patients With Obstructive Hypertrophic Cardiomyopathy.
Sheila M Hegde, Steven J Lester, Scott D Solomon, Michelle Michels, Perry M Elliott, Sherif F Nagueh, Lubna Choudhury, David Zemanek, Donna R Zwas, Daniel Jacoby, Andr...> ;Journal of the American College of Cardiology. 2021 Dec 21
Initial Derivation of a Predictive Model for Left Ventricular Longitudinal Strain (LS) in Early Sepsis.
Daniel B. Knox, Michael J. Lanspa, Emily L. Wilson, Benjamin Haaland, Sarah J. Beesley, Eliotte L. Hirshberg, Theodore P. Abraham, Saraschandra Vallabhajosyula, Colin ...> ;Journal of Intensive Care Medicine. 2021 Nov 10
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Press Mentions

American Society of Echocardiography Welcomes Nine New Board MembersApril 21st, 2022
This Week’s Books in MedicineJune 15th, 2021
Cardiac Echo Tracks Checkpoint Inhibitor DamageFebruary 3rd, 2020
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Grant Support

Development Of A Hypertrophic Cardiomyopathy ConsortiumNational Heart, Lung, And Blood Institute2010–2012
Vevo 2100National Center For Research Resources2011
Animal Model, Tissue/Cell Harvesting, And Phenotyping CoreNational Heart, Lung, And Blood Institute2010–2011
Androgens And Myocardial Relaxation In The Aging HeartNational Institute On Aging2004–2008
Modulation Of Cardiac Mechanics In AL AmyloidosisNational Heart, Lung, And Blood Institute2004–2005