TheodoreWillisLaetschJr.MD

PubMed

• Absolute neutrophil count clinical trial eligibility criteria for pediatric oncology phase I and phase I/II trials by sponsorship.
  Jenny Ruiz, Rebecca K Kelly, Richard Aplenc, Theodore W Laetsch, Alix E Seif> ;Pediatric Blood & Cancer. 2024 May 1
• 1 citations
  Rare Tumors: Opportunities and challenges from the Children's Oncology Group perspective.
  Kris Ann P Schultz, Murali Chintagumpala, Jin Piao, Kenneth S Chen, Rachana Shah, Robyn D Gartrell, Emily Christison-Lagay, Farzana Pashnakar, Jesse L Berry, Allison F...> ;EJC Paediatric Oncology. 2023 Dec 1
• Tisagenlecleucel utilisation and outcomes across refractory, first relapse and multiply relapsed B-cell acute lymphoblastic leukemia: a retrospective analysis of real-...
  Valentin Barsan, Yimei Li, Snehit Prabhu, Christina Baggott, Khanh Nguyen, Holly Pacenta, Christine L Phillips, Jenna Rossoff, Heather Stefanski, Julie-An Talano, Amy ...> ;Eclinicalmedicine. 2023 Nov 1
• Safety of current treatment options for NTRK fusion-positive cancers.
  Adeline T Yang, Theodore Willis Laetsch> ;Expert Opinion on Drug Safety. 2023 Nov 28
• Practice Preferences for Consolidative Hematopoietic Stem Cell Transplantation Following Tisagenlecleucel in Children and Young Adults with B Cell Acute Lymphoblastic ...
  Amy Moskop, Lena E Winestone, Christina Baggott, Julie-An Talano, Deborah Schiff, Jenna Rossoff, Arunkumar Modi, Michael R Verneris, Theodore W Laetsch, Liora Schultz,...> ;Transplantation and Cellular Therapy. 2024 Jan 1
• 3 citations
  INSPIRED Symposium Part 1: Clinical Variables Associated with Improved Outcomes for Children and Young Adults treated with Chimeric Antigen Receptor T cells for B cell...
  Regina M Myers, Elad Jacoby, Michael A Pulsipher, Marcelo C Pasquini, Stephan A Grupp, Nirali N Shah, Theodore W Laetsch, Kevin J Curran, Liora M Schultz> ;Transplantation and Cellular Therapy. 2023 Oct 1
• Children's Oncology Group's 2023 blueprint for research: Rare tumors.
  Kris Ann P Schultz, Murali Chintagumpala, Jin Piao, Kenneth S Chen, Robyn Gartrell, Emily Christison-Lagay, Jesse L Berry, Rachana Shah, Theodore W Laetsch> ;Pediatric Blood & Cancer. 2023 Sep 1
• 1 citations
  HLH-like toxicities predict poor survival after the use of tisagenlecleucel in children and young adults with B-ALL.
  Kevin O McNerney, Stephanie J Si Lim, Kyle Ishikawa, Alexandra Dreyzin, Anant Vatsayan, John J Chen, Christina Baggott, Snehit Prabhu, Holly L Pacenta, Christine Phili...> ;Blood Advances. 2023 Jun 27
• 1 citations
  Clinical Targeted Next-Generation Panel Sequencing RevealsAmplification Is a Poor Prognostic Factor in Osteosarcoma.
  Amanda E Marinoff, Liam F Spurr, Christina Fong, Yvonne Y Li, Suzanne J Forrest, Abigail Ward, Duong Doan, Laura Corson, Audrey Mauguen, Navin Pinto, Luke Maese, Susan...> ;JCO Precision Oncology. 2023 Mar 1
• 48 citations
  Preinfusion factors impacting relapse immunophenotype following CD19 CAR T cells.
  Adam J Lamble, Regina M Myers, Agne Taraseviciute, Samuel John, Bonnie Yates, Seth M Steinberg, Jennifer Sheppard, Alexandra E Kovach, Brent Wood, Michael J Borowitz, ...> ;Blood Advances. 2023 Feb 28
• 22 citations
  Outcomes After Nonresponse and Relapse Post-Tisagenlecleucel in Children, Adolescents, and Young Adults With B-Cell Acute Lymphoblastic Leukemia.
  Liora M Schultz, Anne Eaton, Christina Baggott, Jenna Rossoff, Snehit Prabhu, Amy K Keating, Christa Krupski, Holly Pacenta, Christine L Philips, Julie-An Talano, Amy ...> ;Journal of Clinical Oncology. 2023 Jan 10
• 1 citations
  Testing methods to diagnose TRK fusion cancer - a plain language summary and patient perspective.
  Erin R Rudzinski, Alexander Drilon, Amy Moore, Susan Spinosa, Michaela Willi, Theodore W Laetsch> ;Future Oncology. 2022 Dec 1
• Mediport use as an acceptable standard for CAR T cell infusion.
  Toner, K. N., Maya Eylon, Snehit Prabhu, Samuel John, Maxwell J M King, Dhruv Bhatt, Kevin J Curran, Courtney Erickson, Nicole A Karras, Christine L Phillips, Prakash ...> ;Frontiers in Immunology. 2023 Jan 1
• Non-viral nitric oxide-based gene therapy improves perfusion and liposomal doxorubicin sonopermeation in neuroblastoma models.
  Aditi Bellary, Chance Nowak, Isabella Iwanicki, Fernando Flores-Guzman, Lydia Wu, Jessica J Kandel, Theodore W Laetsch, Leonidas Bleris, Sonia L Hernandez, Shashank R ...> ;Theranostics. 2023 Jan 1
• 53 citations
  Three-Year Update of Tisagenlecleucel in Pediatric and Young Adult Patients With Relapsed/Refractory Acute Lymphoblastic Leukemia in the ELIANA Trial.
  Theodore W Laetsch, Shannon L Maude, Susana Rives, Hidefumi Hiramatsu, Henrique Bittencourt, Peter Bader, André Baruchel, Michael Boyer, Barbara De Moerloose, Muna Qay...> ;Journal of Clinical Oncology. 2023 Mar 20
• Targeting the DNA damage response in pediatric malignancies.
  Jenna M Gedminas, Theodore W Laetsch> ;Expert Review of Anticancer Therapy. 2022 Oct 1
• 8 citations
  Temsirolimus combined with cyclophosphamide and etoposide for pediatric patients with relapsed/refractory acute lymphoblastic leukemia: a Therapeutic Advances in Child...
  Sarah K Tasian, Lewis B Silverman, James A Whitlock, Richard Sposto, Joseph P Loftus, Eric S Schafer, Kirk R Schultz, Raymond J Hutchinson, Paul S Gaynon, Etan Orgel, ...> ;Haematologica. 2022 Oct 1
• 5 citations
  A Phase I Trial of TB-403 in Relapsed Medulloblastoma, Neuroblastoma, Ewing Sarcoma, and Alveolar Rhabdomyosarcoma.
  Giselle Saulnier-Sholler, Dan G Duda, Genevieve Bergendahl, David Ebb, Matija Snuderl, Theodore W Laetsch, Jennifer Michlitsch, Derek Hanson, Michael S Isakoff, Kevin ...> ;Clinical Cancer Research. 2022 Sep 15
• 6 citations
  Low rate of subsequent malignant neoplasms after CD19 CAR T-cell therapy.
  Emily M Hsieh, Regina M Myers, Bonnie Yates, Colleen Annesley, Samuel John, Agne Taraseviciute, Seth M Steinberg, Jennifer Sheppard, Perry Chung, Lee Chen, Daniel W Le...> ;Blood Advances. 2022 Sep 13
• 3 citations
  A phase II study of TAS-117 in patients with advanced solid tumors harboring germline-inactivating mutations.
  Jordi Rodón, Pauline Funchain, Theodore W Laetsch, Hendrik-Tobias Arkenau, Alice Hervieu, Christian F Singer, Yonina R Murciano-Goroff, Sant P Chawla, Kristin Anthony,...> ;Future Oncology. 2022 Sep 1
• 3 citations
  Pediatric Non-Myofibroblastic Primitive Spindle Cell Tumors withGene Rearrangements and Response to Crizotinib.
  Dinesh Rakheja, Jason Y Park, Neil J Fernandes, Tanya C Watt, Theodore W Laetsch, Rebecca R J Collins> ;International Journal of Surgical Pathology. 2022 Sep 1
• Editorial.
  Marilyn M Li, Alexander Drilon, Theodore W Laetsch> ;Cancer Genetics. 2022 Aug 1
• 14 citations
  Molecular profiling identifies targeted therapy opportunities in pediatric solid cancer.
  Alanna J Church, Laura B Corson, Pei-Chi Kao, Alma Imamovic-Tuco, Deirdre Reidy, Duong Doan, Wenjun Kang, Navin Pinto, Luke Maese, Theodore W Laetsch, AeRang Kim, Susa...> ;Nature Medicine. 2022 Aug 1
• 20 citations
  Real-world use of tisagenlecleucel in infant acute lymphoblastic leukemia.
  Amy Moskop, Lauren Pommert, Christina Baggott, Snehit Prabhu, Holly L Pacenta, Christine L Phillips, Jenna Rossoff, Heather E Stefanski, Julie-An Talano, Steve P Margo...> ;Blood Advances. 2022 Jul 26
• 2 citations
  NTRK-fusions in pediatric thyroid tumors: Current state and future perspectives.
  Victoria Casado-Medrano, Alison O'Neill, Stephen Halada, Theodore W Laetsch, Andrew J Bauer, Aime T Franco> ;Cancer Genetics. 2022 Jun 1
• Join now to see all

Journal Articles

• Clinical Pharmacology of Tisagenlecleucel in B-cell Acute Lymphoblastic Leukemia  
  Michael W Boyer, Bruce L Levine, Carl H June, Theodore W Laetsch, Clinical Cancer Research

Lectures

• Molecular Detection of Minimal Residual Disease Precedes Morphological Relapse and Could be Used to Identify Relapse in Pediatric and Young Adult B-Cell Acute Lymphobl... 
  2018 ASH Annual Meeting - San Diego, CA - 12/1/2018