TheodoreBruceMooreMD

Pediatric Hematology & Oncology • Los Angeles, CA

UCLA

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Office
UCLA Department of Pediatrics Hematology/Oncology Division
10833 Le Conte Ave., Rm A2-410 MDCC
Los Angeles, CA 90095
Phone+1 310-825-6708

Fax+1 310-825-6708
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Education & Training

UCLA David Geffen School of Medicine/UCLA Medical CenterFellowship, Pediatric Hematology/Oncology, 1992 - 1995
UCLA David Geffen School of Medicine/UCLA Medical CenterResidency, Pediatrics, 1989 - 1992
Oregon Health and Science University School of MedicineClass of 1989

Certifications & Licensure

OR State Medical License 1997 - Present
CA State Medical License 1990 - 2025
American Board of Pediatrics Pediatric Hematology-Oncology

Awards, Honors, & Recognition

Super Doctor SuperDoctors.com

Clinical Trials

Single vs Double Umbilical Cord Blood Transplants in Children With High Risk Leukemia and Myelodysplasia (BMT CTN 0501) Start of enrollment: 2006 Dec 01
Completed
Phase 3
Evaluating the Safety and Effectiveness of Bone Marrow Transplants in Children With Sickle Cell Disease (BMT CTN 0601) Start of enrollment: 2008 Aug 01
Completed
Phase 2
Natural History Study of SCID Disorders Start of enrollment: 2010 Sep 02
Enrolling by invitation
Patients Treated for SCID (1968-Present) Start of enrollment: 2011 May 15
Enrolling by invitation
Haplo T-Cell Depleted Transplantation in High-Risk Sickle Cell Disease Start of enrollment: 2012 Jan 01
Active, not recruiting
Phase 2
Busulfan, Cyclophosphamide, and Melphalan or Busulfan and Fludarabine Phosphate Before Donor Hematopoietic Cell Transplant in Treating Younger Patients With Juvenile Myelomonocytic Leukemia Start of enrollment: 2013 Jun 24
Completed
Phase 2
Autologous CD34+ Hematopoietic Stem Cells Transduced ex Vivo With Elongation Factor 1 Alpha Shortened (EFS) Lentiviral Vector Encoding for the Human ADA Gene Start of enrollment: 2013 Aug 02
Completed
Phase 1, Phase 2
Stem Cell Gene Therapy for Sickle Cell Disease Start of enrollment: 2014 Dec 01
Recruiting
Phase 1, Phase 2
Efficacy and Safety of the Cryopreserved Formulation of OTL-101 in Subjects With ADA-SCID Start of enrollment: 2016 Dec 16
Completed
Phase 1, Phase 2
Myeloablative Conditioning, Prophylactic Defibrotide and Haplo AlloSCT for Patients With Sickle Cell Disease Start of enrollment: 2017 Jul 01
Recruiting
Phase 2
Roles: Principal Investigator, Contact
HeadStart4: Newly Diagnosed Children (<10 y/o) With Medulloblastoma and Other CNS Embryonal Tumors Start of enrollment: 2015 Sep 01
Active, not recruiting
Phase 4
Roles: Contact
A Study to See if an iPhone Weight Management App Can Help Promote Weight Loss in Adolescents and Young Adults After a Stem Cell Transplant Start of enrollment: 2020 Jul 01
Recruiting
Not Applicable
Roles: Principal Investigator, Contact
Conditioning SCID Infants Diagnosed Early Start of enrollment: 2018 Oct 22
Recruiting
Phase 2
Roles: Principal Investigator, Contact
A Trial Comparing Unrelated Donor BMT With IST for Pediatric and Young Adult Patients With Severe Aplastic Anemia (TransIT, BMT CTN 2202) Start of enrollment: 2023 Jan 25
Recruiting
Phase 3
Roles: Contact
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Publications & Presentations

PubMed

Relevance of lymphocyte proliferation to PHA in severe combined immunodeficiency (SCID) and T cell lymphopenia.
Roshini S Abraham, Amrita Basu, Jennifer R Heimall, Elizabeth Dunn, Alison Yip, Malika Kapadia, Neena Kapoor, Lisa Forbes Satter, Rebecca Buckley, Richard O'Reilly, Ge...> ;Clinical Immunology. 2024 Apr 1
Posttransplantation late complications increase over time for patients with SCID: A Primary Immune Deficiency Treatment Consortium (PIDTC) landmark study.
Eissa, H., Thakar, M., Shah, A., Logan, B., Griffith, L., Dong, H., Parrott, R., O'Reilly, R., Dara, J., Kapoor, N., Forbes Satter, L., Chandra, S., Kapadia, M., Chand...> ;The Journal of Allergy and Clinical Immunology. 2024 Jan 1
Pulmonary microbiome and transcriptome signatures reveal distinct pathobiologic states associated with mortality in two cohorts of pediatric stem cell transplant patie...
Gertz, S. J., Gertz, S. J., Hanisch, B. R., Matt S Zinter, Christopher C Dvorak, Madeline Y Mayday, Gustavo Reyes, Miriam R Simon, Emma M Pearce, Hanna Kim, Peter J Sh...> ;Medrxiv. 2023 Nov 29
7 citations
Measuring the effect of newborn screening on survival after haematopoietic cell transplantation for severe combined immunodeficiency: a 36-year longitudinal study from...
Thakar, M., Logan, B., Puck, J., Dunn, E., Buckley, R., Cowan, M., O'Reilly, R., Kapoor, N., Satter, L., Pai, S., Heimall, J., Chandra, S., Ebens, C., Chellapandian, D...> ;Lancet. 2023 Jul 8
1 citations
Longitudinal relationship between the gut microbiota variation and diversity and gut graft-versus-host disease (GVHD) following pediatric allogeneic hematopoietic cell...
Ashley N Gray, Nicole H Tobin, Theodore B Moore, Fan Li, Grace M Aldrovandi> ;International Journal of Medical Microbiology. 2023 May 1
34 citations
HIV-1 remission and possible cure in a woman after haplo-cord blood transplant.
Hsu, J., Jingmei Hsu, Koen Van Besien, Marshall J Glesby, Savita Pahwa, Anne Coletti, Meredith G Warshaw, Larry Petz, Theodore B Moore, Ya Hui Chen, Suresh Pallikkuth,...> ;Cell. 2023 Mar 16
6 citations
Hypophosphatemia Due to Increased Effector Cell Metabolic Activity Is Associated with Neurotoxicity Symptoms in CD19-Targeted CAR T-cell Therapy.
Jack Pengfei Tang, Cole W Peters, Crystal Quiros, Xiaoyan Wang, Alexandra M Klomhaus, Reiko E Yamada, John M Timmerman, Theodore B Moore, Theodore S Nowicki> ;Cancer Immunology Research. 2022 Dec 2
20 citations
Outcomes following treatment for ADA-deficient severe combined immunodeficiency: a report from the PIDTC.
Cuvelier, G., Logan, B., Prockop, S., Buckley, R., Kuo, C., Griffith, L., Liu, X., Yip, A., Hershfield, M., Ayoub, P., Moore, T., Dorsey, M., O'Reilly, R., Kapoor, N.,...> ;Blood. 2022 Aug 18
80 citations
Autologous Ex Vivo Lentiviral Gene Therapy for Adenosine Deaminase Deficiency.
Donald B. Kohn, Claire Booth, Kit L. Shaw, Jinhua Xu-Bayford, Elizabeth Garabedian, Valentina Trevisan, Denise A. Carbonaro-Sarracino, Kajal Soni, Dayna Terrazas, Kati...> ;The New England Journal of Medicine. 2021 May 11
19 citations
Long-term outcomes after gene therapy for adenosine deaminase severe combined immune deficiency
Bryanna Reinhardt, Omar Habib, Kit L. Shaw, Elizabeth Garabedian, Denise A. Carbonaro-Sarracino, Dayna Terrazas, Beatriz Campo Fernandez, Satiro N. De Oliveira, Theodo...> ;Blood. 2021 Oct 14
11 citations
Stable to improved cardiac and pulmonary function in children with high-risk sickle cell disease following haploidentical stem cell transplantation.
Deborah M. Friedman, Allen J. Dozor, Jordan Milner, Marise D'Souza, Julie-An Talano, Theodore B. Moore, Shalini Shenoy, Qiuhu Shi, Mark C. Walters, Elliott Vichinsky, ...> ;Bone Marrow Transplantation. 2021 May 6
16 citations
Treatment of post-transplant lymphoproliferative disorder (PTLD) in a heart transplant recipient with chimeric antigen receptor T-cell therapy.
James Ch’ng, Matthew Russell, Jerry C Cheng, Theodore B. Moore, Juan C. Alejos, Dang, B. N., Brian N. Dang> ;Pediatric Transplantation. 2021 Aug 1
4 citations
Pediatric hematopoietic cell transplantation: Longitudinal trends in body mass index and outcomes.
Holly Wilhalme, James Ch’ng, Satiro N. De Oliveira, LaVette Bowles, Theodore B. Moore, Dang, B. N., Brian N. Dang> ;Pediatric Transplantation. 2020 Sep 30
3 citations
Successful Use of Hematopoietic Stem Cell Transplantation for 2 Pediatric Cases of Glanzmann Thrombasthenia and Review of the Literature
Brian D. Friend, Gavin D. Roach, Pamela Kempert, Theodore B. Moore> ;Journal of Pediatric Hematology/oncology. 2020 Jul 23
3 citations
AT1R Activating Autoantibodies in Hematopoietic Stem Cell Transplantation.
Kathryn L. Bradford, Meghan H. Pearl, Donald B. Kohn, Patricia L. Weng, Ora Yadin, La Vette Bowles, Satiro N. De Oliveira, Theodore B. Moore> ;Biology of Blood and Marrow Transplantation. 2020 Nov 1
64 citations
Excellent outcomes following hematopoietic cell transplantation for Wiskott-Aldrich syndrome: a PIDTC report
, , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , > ;Blood. 2020 Jun 4
20 citations
A review of nutrition and dietary interventions in oncology
Ashley Gray, Theodore B. Moore, Roger Clemens, Peter Pressman, Dang, B. N., Brian N. Dang> ;SAGE Open Medicine. 2020 Jun 1
4 citations
Successful engraftment of haploidentical bone marrow with post-transplantation cyclophosphamide in patients with aplastic anemia.
Satiro N. De Oliveira, Ashley Gray, LaVette Bowles, Theodore B. Moore, Dang, B. N., Brian N. Dang> ;Pediatric Transplantation. 2020 Mar 1
21 citations
Familial Haploidentical Stem Cell Transplant in Children and Adolescents With High-Risk Sickle Cell Disease: A Phase 2 Clinical Trial.
Mitchell S. Cairo, Julie-An Talano, Theodore B. Moore, Qiuhu Shi, Rona Singer Weinberg, Brenda J. Grossman, Shalini Shenoy> ;JAMA Pediatrics. 2020 Feb 1
12 citations
Identifying risk factors associated with worse outcomes in adolescents and young adults undergoing hematopoietic stem cell transplantation.
Brian D. Friend, Kevin Tang, Daniela Markovic, David Elashoff, Theodore B. Moore, Gary J. Schiller> ;Pediatric Blood & Cancer. 2019 Aug 20
4 citations
The safety and efficacy of clofarabine in combination with high-dose cytarabine and total body irradiation myeloablative conditioning and allogeneic stem cell transpla...
Jessica Hochberg, Stacey Zahler, Mark B. Geyer, Nan Chen, Jennifer Krajewski, Lauren Harrison, O. Militano, M. Fevzi Ozkaynak, Alexandra Cheerva, Julie Talano, Theodor...> ;Bone Marrow Transplantation. 2019 Feb 1
102 citations
Newborn Screening for Severe Combined Immunodeficiency and T-cell Lymphopenia in California, 2010-2017.
George S. Amatuni, Robert J. Currier, Joseph A. Church, Tracey Bishop, Elena Grimbacher, Alan A. Nguyen, Rajni Agarwal-Hashmi, Constantino P. Aznar, Manish J. Butte, M...> ;Pediatrics. 2019 Feb 1
46 citations
The genetic landscape of severe combined immunodeficiency in the United States and Canada in the current era (2010-2018).
, , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , > ;The Journal of Allergy and Clinical Immunology. 2019 Jan 1
Finding the perfect recipe for success.
Theodore B. Moore> ;Pediatric Investigation. 2018 Dec 1
105 citations
SCID genotype and 6-month posttransplant CD4 count predict survival and immune recovery
Elie Haddad, Brent R. Logan, Linda M. Griffith, Rebecca H. Buckley, Roberta E. Parrott, Susan E. Prockop, Trudy N. Small, Jessica Chaisson, Christopher C. Dvorak, Mega...> ;Blood. 2018 Oct 25
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Journal Articles

The Safety and Efficacy of Clofarabine in Combination with High-Dose Cytarabine and Total Body Irradiation Myeloablative Conditioning and Allogeneic Stem Cell Transpla...
Stacey Zahler, Mitchell S Cairo, Jennifer Krajewski, M Fevzi Ozkaynak, Alexandra C Cheerva, Theodore B Moore, Alfred P Gillio, Mark C Walters, Nature

Abstracts/Posters

Sustained Donor Chimerism and Rapid Immune Cell Reconstitution Following Familial Haploidentical (FHI) CD34 Enriched Stem Cell Transplantation with Pbmnc Addback in Pa...
Theodore B. Moore, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019

Lectures

Significantly Improved Long Term Health Related Quality of Life (HRQL) and Neurocognition Following Familial Haploidentical Stem Cell Transplantation (HISCT) Utilizing...
2018 ASH Annual Meeting - San Diego, CA - 12/1/2018

Authored Content

Precision Medicine in Pediatric Neurooncology: A ReviewDecember 2017

Press Mentions

10 Ways an FIU Online Degree Enhances CareersJuly 7th, 2021
Pediatric Cancer Researchers Receive Grants from St. Baldrick’s FoundationApril 17th, 2018

Grant Support

Phase I Dose Escalation Study Of Autologous Tumor Lysate-Pulsed Dendritic CELNational Center For Research Resources2006
OPEN Label, Phase I/II Trial Of Rituximab For Chronic, Severe Idiopathic ThroNational Center For Research Resources2005
Impact Of Body Composition On Pharmacokinetics Of Doxorubicin In Pediatric PANational Center For Research Resources2005
OPEN Label, Phase I/II Trial Of Rituximab For Chronic, Severe Idiopathic Thro...National Center For Research Resources2004
Impact Of Body Composition On Pharmacokinetics Of Doxorubicin In Pediatric Pa...National Center For Research Resources2004
Mechanism N-MYC Oncogene DOWN Regulation By Vitamin DNational Cancer Institute1995