TheresaZesiewiczMD

Neurology • Tampa, FL

Hospital/Neurohospitalist

Professor, Neurology, USF-Morsani

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Office
13330 USF Laurel Drive
3rd Floor
Tampa, FL 33612
Phone+1 813-974-5335

Fax+1 813-974-8032
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Education & Training

SUNY Health Science Center at BrooklynResidency, Neurology, 1989 - 1992
Rutgers HealthInternship, Transitional Year, 1988 - 1989
Rutgers New Jersey Medical SchoolClass of 1988

Certifications & Licensure

FL State Medical License 1993 - 2026
NY State Medical License 1991 - 1994
American Board of Psychiatry and Neurology Neurology

Awards, Honors, & Recognition

CMS Meaningful Use Stage 1 Certification Allscripts Enterprise EHR, Allscripts, 2012-2013

Clinical Trials

Keppra IV for the Treatment of Motor Fluctuations in Parkinson's Disease Start of enrollment: 2007 Dec 01
Withdrawn
Phase 4
Solifenacin Succinate (VESIcare) for the Treatment of Urinary Incontinence in Parkinson's Disease Start of enrollment: 2007 Nov 01
Withdrawn
Phase 4
Pregabalin (Lyrica) for the Treatment of Restless Legs Syndrome Start of enrollment: 2007 Nov 01
Withdrawn
Phase 4
Pregabalin (Lyrica) for the Treatment of Essential Tremor Start of enrollment: 2007 Dec 01
Completed
Phase 4
Pilot Study of Varenicline (Chantix®) in the Treatment of Friedreich's Ataxia Start of enrollment: 2009 May 01
Terminated
Phase 2, Phase 3
Study to Determine the Safety and Tolerability of Varenicline (Chantix®) in Treating Spinocerebellar Ataxia Type 3 Start of enrollment: 2009 Oct 01
Completed
Phase 2
Solifenacin Succinate (VESIcare) for the Treatment of Overactive Bladder in Parkinson's Disease Start of enrollment: 2010 Jan 01
Completed
Phase 4
Natural History Study of and Genetic Modifiers in Spinocerebellar Ataxias Start of enrollment: 2010 Apr 01
Recruiting
Safety and Efficacy of Intravenous Immune Globulin in Treating Spinocerebellar Ataxia Start of enrollment: 2011 Aug 01
Completed
Phase 2
An Open-label Study of the Effects of Acetyl-L-Carnitine on Cardiovascular Outcomes in Friedreich's Ataxia Start of enrollment: 2013 Aug 01
Unknown status
Not Applicable
A Phase 2A Trial of EPI-743 for Patients With Parkinson's Disease Start of enrollment: 2013 Sep 01
Completed
Phase 2
International Ataxia Rating Scale in Younger Patients Start of enrollment: 2013 Aug 01
Completed
EPI-743 in Friedreich's Ataxia Point Mutations Start of enrollment: 2013 Oct 01
Completed
Phase 2
Blinded, Randomized Study of Gabapentin (Neurontin®) and Gabapentin Enacarbil (Horizant™) in Restless Leg Syndrome Start of enrollment: 2014 Apr 01
Terminated
Phase 4
Sagene 2014 - Parkinson's Disease and Erectile Dysfunction Start of enrollment: 2014 Sep 01
Unknown status
Phase 4
Multiple Ascending Dose Study of Intravenously Administered BMS-986168 (BIIB092) in Patients With Progressive Supranuclear Palsy Start of enrollment: 2015 Oct 02
Completed
Phase 1
FA Clinical Outcome Measures Start of enrollment: 2001 Jan 01
Recruiting
Clinical Trial Readiness for SCA1 and SCA3 Start of enrollment: 2018 Aug 16
Active, not recruiting
Preliminary Study of the Scale To Assess Ataxia and Neurologic Dysfunction (STAND) Start of enrollment: 2012 Oct 01
Completed
An Open-label Trial of Intravenous Immune Globulin (IVIG)in Treating Spinocerebellar Ataxias Start of enrollment: 2015 Apr 01
Unknown status
Phase 1
A First in Human Study of RT001 in Patients With Friedreich's Ataxia Start of enrollment: 2015 Aug 01
Completed
Phase 1, Phase 2
A Pharmacokinetics and Safety Study of BIIB132 in Adults With Spinocerebellar Ataxia 3 Start of enrollment: 2022 Feb 02
Terminated
Phase 1
Roles: Principal Investigator
Pimavanserin vs. Quetiapine for Treatment of Parkinson's Psychosis Start of enrollment: 2022 Oct 24
Recruiting
Phase 4
Roles: Contact
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Publications & Presentations

PubMed

Fatigue Impacts Quality of Life in People with Spinocerebellar Ataxias.
Ruo-Yah Lai, Christian Rummey, Christian J Amlang, Chi-Ying R Lin, Tiffany X Chen, Susan Perlman, George Wilmot, Christopher M Gomez, Jeremy D Schmahmann, Henry Paulso...> ;Movement Disorders Clinical Practice. 2024 Feb 29
The Cerebellar Cognitive Affective/Schmahmann Syndrome Scale in Spinocerebellar Ataxias.
Selvadurai, L., Perlman, S., Ashizawa, T., Wilmot, G., Onyike, C., Rosenthal, L., Shakkottai, V., Paulson, H., Subramony, S., Bushara, K., Kuo, S., Dietiker, C., Gesch...> ;Cerebellum. 2024 Jan 2
2 citations
Propensity matched comparison of omaveloxolone treatment to Friedreich ataxia natural history data.
David R Lynch, Angie Goldsberry, Christian Rummey, Jennifer Farmer, Sylvia Boesch, Martin B Delatycki, Paola Giunti, J Chad Hoyle, Caterina Mariotti, Katherine D Mathe...> ;Annals of Clinical and Translational Neurology. 2024 Jan 1
2 citations
Evaluation of Cerebellar Ataxic Patients.
Sara Radmard, Theresa A Zesiewicz, Sheng-Han Kuo> ;Neurologic Clinics. 2023 Feb 1
Deep brain stimulation for chronic pain: a systematic review and meta-analysis.
Nour Shaheen, Ahmed Shaheen, Abdelrahman Elgendy, Yarema B Bezchlibnyk, Theresa Zesiewicz, Brian Dalm, Jennifer Jain, Alexander L Green, Tipu Z Aziz, Oliver Flouty> ;Frontiers in Human Neuroscience. 2023 Jan 1
1 citations
Deep brain stimulation for substance use disorder: a systematic review and meta-analysis.
Nour Shaheen, Ahmed Shaheen, Can Sarica, Arun Singh, Mario Zanaty, Karim Johari, Andrew Yang, Theresa Zesiewicz, Brian Dalm, Yarema Bezchlibnyk, Andres M Lozano, Olive...> ;Frontiers in Psychiatry. 2023 Jan 1
3 citations
Double blind trial of a deuterated form of linoleic acid (RT001) in Friedreich ataxia.
David R Lynch, Katherine D Mathews, Susan Perlman, Theresa Zesiewicz, Sub Subramony, Omid Omidvar, Adam P Vogel, Ana Krtolica, Nadia Litterman, Lex van der Ploeg, Fred...> ;Journal of Neurology. 2023 Mar 1
21 citations
Efficacy of Omaveloxolone in Friedreich's Ataxia: Delayed-Start Analysis of the MOXIe Extension.
David R Lynch, Melanie P Chin, Sylvia Boesch, Martin B Delatycki, Paola Giunti, Angie Goldsberry, J Chad Hoyle, Caterina Mariotti, Katherine D Mathews, Wolfgang Nachba...> ;Movement Disorders. 2023 Feb 1
2 citations
Frataxin deficiency alters gene expression in Friedreich ataxia derived IPSC-neurons and cardiomyocytes.
Mariana B Angulo, Alexander Bertalovitz, Mariana A Argenziano, Jiajia Yang, Aarti Patel, Theresa Zesiewicz, Thomas V McDonald> ;Molecular Genetics & Genomic Medicine. 2023 Jan 1
4 citations
The S-Factor, a New Measure of Disease Severity in Spinocerebellar Ataxia: Findings and Implications.
Louisa P Selvadurai, Susan L Perlman, George R Wilmot, Sub H Subramony, Christopher M Gomez, Tetsuo Ashizawa, Henry L Paulson, Chiadi U Onyike, Liana S Rosenthal, Hari...> ;Cerebellum. 2023 Oct 1
2 citations
Therapies, Research Funding, and Racial Diversity in Essential Tremor: A Systematic Review of the Literature.
Theresa Zesiewicz, Joshua Vega, Clifton Gooch, Shaila Ghanekar, Yangxin Huang, Yarema Bezchlibnyk, Joseph Staffetti, Chase Kingsbury> ;Movement Disorders Clinical Practice. 2022 Aug 1
13 citations
Natural History of Friedreich Ataxia: Heterogeneity of Neurologic Progression and Consequences for Clinical Trial Design.
Christian Rummey, Louise A Corben, Martin Delatycki, George Wilmot, Sub H Subramony, Manuela Corti, Khalaf Bushara, Antoine Duquette, Christopher Gomez, J Chad Hoyle, ...> ;Neurology. 2022 Oct 3
8 citations
Current and emerging treatment modalities for spinocerebellar ataxias.
Shaila D Ghanekar, Sheng-Han Kuo, Joseph S Staffetti, Theresa A Zesiewicz> ;Expert Review of Neurotherapeutics. 2022 Feb 1
2 citations
A non-synonymous single nucleotide polymorphism inpredicts neurological severity in Friedreich ataxia.
Layne N Rodden, Christian Rummey, Yi Na Dong, Sarah Lagedrost, Sean Regner, Alicia Brocht, Khalaf Bushara, Martin B Delatycki, Christopher M Gomez, Katherine Mathews, ...> ;Frontiers in Molecular Biosciences. 2022 Jan 1
2 citations
Body Mass Index and Height in the Friedreich Ataxia Clinical Outcome Measures Study.
Maya Patel, Ashley McCormick, Jaclyn Tamaroff, Julia Dunn, Jonathan A. Mitchell, Kimberly Y. Lin, Jennifer M. Farmer, Christian Rummey, Susan Perlman, Martin B. Delaty...> ;Neurology. Genetics. 2021 Nov 12
8 citations
Scoliosis in Friedreich's ataxia: longitudinal characterization in a large heterogeneous cohort.
Christian Rummey, John M. Flynn, Louise A. Corben, Martin B. Delatycki, George Wilmot, S. H. Subramony, Khalaf Bushara, Antoine Duquette, Christopher M. Gomez, J. Chad...> ;Annals of Clinical and Translational Neurology. 2021 May 5
11 citations
A Phase 2 Proof-of-Concept, Randomized, Placebo-Controlled Trial of CX-8998 in Essential Tremor.
Spyros Papapetropoulos, Margaret Lee, Stacey Versavel, Evan Newbold, Hyder A. Jinnah, Rajesh Pahwa, Kelly E. Lyons, Rodger J. Elble, William G. Ondo, Theresa A. Zesiew...> ;Movement Disorders. 2021 Aug 1
6 citations
The Responsiveness of Gait and Balance Outcomes to Disease Progression in Friedreich Ataxia.
Sarah C Milne, Seok Hun Kim, Anna Murphy, Jane Larkindale, Jennifer M. Farmer, Ritchie Malapira, Mary Danoudis, Jessica D. Shaw, Tyagi Ramakrishnan, Fatemeh Rasouli, E...> ;Cerebellum. 2021 Mar 20
54 citations
Safety and efficacy of tilavonemab in progressive supranuclear palsy: a phase 2, randomised, placebo-controlled trial.
Günter U. Höglinger, Irene Litvan, Nuno Mendonca, Deli Wang, Hui Zheng, Beatrice Rendenbach-Mueller, Hoi-Kei Lon, Ziyi Jin, Nahome Fisseha, Kumar Budur, Michael Gold, ...> ;The Lancet. Neurology. 2021 Mar 1
35 citations
Assessment of Ataxia Rating Scales and Cerebellar Functional Tests: Critique and Recommendations
Santiago Perez-Lloret, Bart P.C. van de Warrenburg, Malco Rossi, Carmen Rodriguez-Blazquez, Theresa A. Zesiewicz, Jonas Alex Morales Saute, Alexandra Durr, Masatoyo Ni...> ;Movement Disorders. 2021 Feb 1
97 citations
Safety and Efficacy of Omaveloxolone in Friedreich Ataxia (MOXIe Study).
David A. Lynch, Melanie P. Chin, Martin B. Delatycki, S. H. Subramony, Manuela Corti, J. Chad Hoyle, Sylvia Boesch, Wolfgang Nachbauer, Caterina Mariotti, Katherine D....> ;Annals of Neurology. 2021 Feb 1
17 citations
Emerging therapies in Friedreich's ataxia
Theresa A. Zesiewicz, Joshua Hancock, Shaila Ghanekar, Sheng-Han Kuo, Carlos A. Dohse, Joshua Vega> ;Expert Review of Neurotherapeutics. 2020 Sep 21
2 citations
Dysphagia in spinocerebellar ataxias type 1, 2, 3 and 6.
Chen Ya Yang, Ruo Yah Lai, Nadia Amokrane, Chi-Ying Lin, Karla P. Figueroa, Stefan M. Pulst, Susan Perlman, George Wilmot, Christopher M. Gomez, Jeremy D. Schmahmann, ...> ;Journal of the Neurological Sciences. 2020 Aug 15
29 citations
Prospective Home-use Study on Non-invasive Neuromodulation Therapy for Essential Tremor.
Stuart Isaacson, Elizabeth Peckham, Winona Tse, Olga Waln, Christopher Way, Melita T. Petrossian, Nabila Dahodwala, Michael J. Soileau, Mark F. Lew, Cameron Dietiker, ...> ;Tremor and Other Hyperkinetic Movements. 2020 Aug 14
10 citations
Test-retest reliability of the Friedreich's ataxia rating scale.
Christian Rummey, Theresa A. Zesiewicz, Santiago Perez-Lloret, Jennifer M. Farmer, Massimo Pandolfo, David A. Lynch> ;Annals of Clinical and Translational Neurology. 2020 Aug 11
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Press Mentions

Cala Health Launches Trial for Cala Two Neurostim Device for Essential TremorJanuary 17th, 2019
Updated Guideline for Treating Essential TremorOctober 20th, 2011
Most Patients Stop Drugs for Essential Tremor After Deep Brain Stimulation SurgeryApril 7th, 2011
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Committees

Member, Guideline Development Subcommittee of the American Academy of Neurology 2016 - Present
Member, Parkinson's Disease Practice Guidelines Committee