ThienDTranMD

PubMed

• Small Molecules Targeting Hepatitis C Virus-Encoded NS5A Cause Subcellular Redistribution of their Target: Insights into Compound Mode of Action.
  Targett-Adams, P., Graham, E.S., Middleton, J., Palmer, A., Shaw, S.M., Lavender, H., Brain, P., Tran, T.D., Jones, L.H., Wakenhut, F., Stammen, B., Pryde, D., Pickfor...> ;J Virol. 2011 Jul
• Design and optimisation of orally active TLR7 agonists for the treatment of hepatitis C virus infection.
  Tran, T. D., Pryde, D. C., Jones, P., Adam, F. M., Benson, N., Bish, G., Calo, F., Ciaramella, G., Dixon, R., Duckworth, J., Fox, D. N., Hay, D. A., Hitchin, J., Horsc...> ;Bioorg Med Chem Lett. 2011 Apr 15
• Aldehyde oxidase: an enzyme of emerging importance in drug discovery.
  Pryde, D. C., Dalvie, D., Hu, Q., Jones, P., Obach, R. S., Tran, T. D.> ;J Med Chem. 2010 Dec 23
• Design and optimisation of potent gp120-CD4 inhibitors.
  Tran, T. D., Adam, F. M., Calo, F., Fenwick, D. R., Fok-Seang, J., Gardner, I., Hay, D. A., Perros, M., Rawal, J., Middleton, D. S., Parkinson, T., Pickford, C., Platt...> ;Bioorg Med Chem Lett. 2009 Sep 01
• Discovery of a small molecule inhibitor through interference with the gp120-CD4 interaction.
  Williams, D. H., Adam, F., Fenwick, D. R., Fok-Seang, J., Gardner, I., Hay, D., Jaiessh, R., Middleton, D. S., Mowbray, C. E., Parkinson, T., Perros, M., Pickford, C.,...> ;Bioorg Med Chem Lett. 2009 Sep 01
• In-cell click labelling of small molecules to determine subcellular localisation.
  Jones, L. H., Beal, D., Selby, M. D., Everson, O., Burslem, G. M., Dodd, P., Millbank, J., Tran, T. D., Wakenhut, F., Graham, E. J., Targett-Adams, P.> ;J Chem Biol. 2011 Apr
• Discovery of a highly potent series of TLR7 agonists.
  Jones, P., Pryde, D. C., Tran, T. D., Adam, F. M., Bish, G., Calo, F., Ciaramella, G., Dixon, R., Duckworth, J., Fox, D. N., Hay, D. A., Hitchin, J., Horscroft, N., Ho...> ;Bioorg Med Chem Lett. 2011 Oct 1
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