
Thomas B. Casale MD FACP, FAAAAI, FACAAI
Asthma & Allergic Conditions
Professor of Medicine and Pediatrics, Director of Clinical and Translational Research, University of South Florida, Tampa, FL
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USF, 12901 Bruce B Downs BlvdMDC 19Tampa, FL 33612
Phone+1 813-974-8954
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Education & Training
National Institutes of Health Clinical CenterFellowship, Allergy and Immunology, 1982 - 1984
Graduate School at the National Institutes of HealthNo Degree, 1980 - 1982
Baylor College of MedicineResidency, Internal Medicine, 1977 - 1980
Chicago Medical School at Rosalind Franklin University of Medicine and ScienceClass of 1977
Graduate School in Microbiology, University of Illinois Medical SchoolNo Degree, 1973 - 1974
Certifications & Licensure
FL State Medical License 2014 - 2028
NE State Medical License 1996 - 2014
IA State Medical License 1984 - 2001
TX State Medical License 1978 - 1987
DC State Medical License 1983 - 1984
MD State Medical License 1983 - 1984
American Board of Allergy and Immunology Allergy & Immunology
American Board of Internal Medicine Internal Medicine
Awards, Honors, & Recognition
- Faculty Outstanding Research Achievement Awards Univ South Florida, 2023
- Creighton University faculty wall of scholarship Creighton University, 2023
- World’s top 2% most influential scientists and one of the best medicine and immunology scientists in the United States Research.com, 2022-2023
Clinical Trials
- Omalizumab (Xolair) and Allergy Shots For the Treatment of Seasonal Allergies Start of enrollment: 2003 Apr 01
- Effect of Xolair on Airway Hyperresponsiveness Start of enrollment: 2004 Jan 01
- Mometasone and Markers of Airway Inflammation Start of enrollment: 2005 Aug 01
Publications & Presentations
PubMed
- Methodology for the Development of the Allergic Rhinitis and Its Impact on Asthma (ARIA)-EAACI 2024-2025 Guidelines: From Evidence-to-Decision Frameworks to Digitalise...Jean Bousquet, Bernardo Sousa-Pinto, Rafael José Vieira, Holger J Schünemann, Torsten Zuberbier
Allergy. 2026-02-01 - Dupilumab Improves Health-Related Quality of Life in Omalizumab-Naïve Patients with Chronic Spontaneous Urticaria.Ana M Giménez-Arnau, Thomas B Casale, Gil Yosipovitch, Luis Felipe Ensina, Naoko Inomata
Dermatology and Therapy. 2026-01-01 - Allergic Rhinitis and Its Impact on Asthma (ARIA)-EAACI Guidelines-2024-2025 Revision: Part I-Guidelines on Intranasal Treatments.Bernardo Sousa-Pinto, Jean Bousquet, Rafael José Vieira, Holger J Schünemann, Torsten Zuberbier
Allergy. 2025-12-01
Journal Articles
- Rostrum Harmonization of Terminology for Tolerated and Reactive Dose in Food Allergy ImmunotherapyThomas B Casale, Panida Sriaroon, ScienceDirect
- Ask the Expert Can Xolair Be Used in Nonallergic Asthmatic?Thomas B Casale, Dennis K Ledford, ScienceDirect
- In-Flight Medical EmergenciesCasale TB, Lemanske RF Jr, N Engl J Med, 1/21/2016
Books/Book Chapters
Abstracts/Posters
- Biomarkers Associated with Response in Patients Initiating Omalizumab: Baseline Levels Among Patients in the Prospective Observational Study to Evaluate Predictors of ...Bradley E. Chipps, William W. Busse, Allan T. Luskin, MD, Robert S. Zeiger, Benjamin Trzaskoma, Hooman Pazwash, Theodore A. Omachi, and Thomas B. Casale, Journal of Allergy and Clinical Immunology, 1/1/2016
- Once-Daily Tiotropium Respimat® Add-on to at Least Ics Maintenance Therapy Demonstrates Improved Asthma Control in Patients with Symptomatic Asthma, Independent of Ser...Mark L. Vandewalker, Johann Christian Virchow, Thomas B. Casale, Michael Engel, Petra Moroni-Zentgraf, Reinhold Luhmann, Ronald Dahl, Journal of Allergy and Clinical Immunology, 1/1/2016
- Tiotropium Respimat® Add-on to at Least Ics Therapy Demonstrates Reduced Risk of Severe Asthma Exacerbation and Asthma Worsening in Symptomatic Asthma, Independent of ...Thomas B. Casale, Donald P. Tashkin, Reinhold Luhmann, Michael Engel, Petra Moroni-Zentgraf, Journal of Allergy and Clinical Immunology, 1/1/2016
Lectures
- Plenary: Immunoglobulin E: The First 50 Years and Beyond-Role and Limitations of IgE in Diagnosis and Treatment of Allergic Disease.Los Angeles, CA - 1/1/2016
- Multiallergen vs. single allergen immunotherapy in SLIT vs. SCIT.Palm Beach, FL - 1/1/2016
- Chronic urticaria: New pathophysiologic insights.Palm Beach, FL - 1/1/2016
Other
- Clinical Communications Real-World Attitudes Among Allergists/Immunologists Regarding Oral Immunotherapy and Preferred TerminologyThomas Casale, MD, ScienceDirect
https://www.doximity.com/articles/7f90d894-c9f9-4aa2-9628-21b2b51f02b1
UpToDate, Wolters Kluwer Health - 2012-10-22 - Review and Feature Article Emerging Biomarkers and Therapeutic Pipelines for Chronic Spontaneous UrticariaThomas Casale, MD, ScienceDirect
https://www.doximity.com/articles/b65f9083-6415-4836-b6ec-33eae5c35286
UpToDate, Wolters Kluwer Health - 2012-10-24 - The relationship between IgE and allergic disease.Stokes J, Casale TB, Up To Date
1/1/2013
Press Mentions
Real-World Evidence Supports Clinical Effectiveness of Neffy® (Epinephrine Nasal Spray) in Patients Experiencing AnaphylaxisSeptember 9th, 2025
Real-World Evidence Supports Clinical Effectiveness of Neffy® (Epinephrine Nasal Spray) in Patients Experiencing AnaphylaxisSeptember 8th, 2025
Tezspire Treats Chronic Sinus Symptoms with Nasal PolypsMarch 2nd, 2025
Professional Memberships
- Fellow
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