ThomasFernandezMD

PubMed

• Intense Imagery Movements May Lead to Maladaptive Daydreaming: A Case Series and Literature Review.
  Tammy Hedderly, Claire Eccles, Osman Malik, Farah Abdulsatar, Clare Mitchell, Tamsin Owen, Nirit Soffer-Dudek, Claire Grose, Sally Robinson, Eli Somer, Thomas V Fernandez> ;Movement Disorders Clinical Practice. 2024 Mar 27
• 1 citations
  Rare X-linked variants carry predominantly male risk in autism, Tourette syndrome, and ADHD.
  Sheng Wang, Belinda Wang, Vanessa Drury, Sam Drake, Nawei Sun, Hasan Alkhairo, Juan Arbelaez, Clif Duhn, , Vanessa H Bal, Kate Langley, Joanna Martin, Pieter J Hoekstr...> ;Nature Communications. 2023 Dec 6
• Clinical characteristics of probands with obsessive-compulsive disorder from simplex and multiplex families.
  Lima, M., Saraiva, L., Ramos, V., Oliveira, M., Costa, D., , Crowley, J., Storch, E., Shavitt, R., Miguel, E., Cappi, C., Fernandez, T.> ;Psychiatry Research. 2024 Jan 1
• Protocol description for a randomized controlled trial of fMRI neurofeedback for tics in adolescents with Tourette Syndrome.
  Jitendra Awasthi, Cheyenne Harris-Starling, Carla Kalvin, Brian Pittman, Haesoo Park, Michael Bloch, Thomas V Fernandez, Denis G Sukhodolsky, Michelle Hampson> ;Psychiatry Research. Neuroimaging. 2023 Dec 1
• 5 citations
  Characteristics of trichotillomania and excoriation disorder across the lifespan.
  Ashley Lin, Luis C Farhat, José M Flores, Jessica L S Levine, Thomas V Fernandez, Michael H Bloch, Emily Olfson> ;Psychiatry Research. 2023 Apr 1
• 3 citations
  Whole-exome DNA sequencing in childhood anxiety disorders identifies rare de novo damaging coding variants.
  Emily Olfson, Eli R Lebowitz, Grace Hommel, Neha Pashankar, Wendy K Silverman, Thomas V Fernandez> ;Depression and Anxiety. 2022 Jun 1
• 11 citations
  Whole-exome sequencing identifies genes associated with Tourette's disorder in multiplex families.
  Xiaolong Cao, Yeting Zhang, Mohamed Abdulkadir, Li Deng, Thomas V. Fernandez, Blanca Garcia-Delgar, Julie Hagstrøm, Pieter J. Hoekstra, Robert A. King, Justin Koesteri...> ;Molecular Psychiatry. 2021 Apr 9
• 48 citations
  De Novo Damaging DNA Coding Mutations Are Associated With Obsessive-Compulsive Disorder and Overlap With Tourette's Disorder and Autism.
  Carolina Cappi, Melody E. Oliphant, Zsanett Péter, Gwyneth Zai, Maria Conceição do Rosário, Catherine Sullivan, Abha R. Gupta, Ellen J. Hoffman, Manmeet Virdee, Emily ...> ;Biological Psychiatry. 2020 Jun 15
• 158 citations
  Interrogating the Genetic Determinants of Tourette’s Syndrome and Other Tic Disorders Through Genome-Wide Association Studies
  Dongmei Yu, Jae Hoon Sul, Fotis Tsetsos, Muhammad Nawaz, Alden Y. Huang, Ivette Zelaya, Cornelia Illmann, Lisa Osiecki, Sabrina M. Darrow, Matthew E. Hirschtritt, Eric...> ;The American Journal of Psychiatry. 2019 Mar 1
• 25 citations
  De Novo Sequence and Copy Number Variants Are Strongly Associated with Tourette Disorder and Implicate Cell Polarity in Pathogenesis.
  Sheng Wang, Jeffrey D Mandell, Yogesh Kumar, Nawei Sun, Montana T Morris, Juan Arbelaez, Cara Nasello, Shan Dong, Clif Duhn, Xin Zhao, Zhiyu Yang, Shanmukha S Padmanab...> ;Cell Reports. 2018 Sep 25
• 17 citations
  Genetic Insights Into ADHD Biology.
  Victoria Hayman, Thomas V. Fernandez> ;Frontiers in Psychiatry. 2018 Jun 7
• 25 citations
  Tourette disorder and other tic disorders.
  Thomas V. Fernandez, Matthew W. State, Christopher Pittenger> ;Handbook of Clinical Neurology. 2018 Jan 1
• 11 citations
  Genetic susceptibility in obsessive-compulsive disorder.
  Thomas V. Fernandez, James F. Leckman, Christopher Pittenger> ;Handbook of Clinical Neurology. 2018 Jan 1
• 37 citations
  Extended-Release Guanfacine Does Not Show a Large Effect on Tic Severity in Children with Chronic Tic Disorders
  Tanya K. Murphy, Thomas V. Fernandez, Barbara J. Coffey, Omar Rahman, Allison Gavaletz, Camille E. Hanks, Caitlin S. Tillberg, Laura Ibanez Gomez, Denis G. Sukhodolsky...> ;Journal of Child and Adolescent Psychopharmacology. 2017 Nov 1
• 113 citations
  De Novo Coding Variants Are Strongly Associated with Tourette Disorder.
  A. J. Willsey, Thomas V. Fernandez, Dongmei Yu, Robert A. King, Andrea Dietrich, Jinchuan Xing, Stephen Sanders, Jeffrey D. Mandell, Alden Y. Huang, P. Richer, Louw Sm...> ;Neuron. 2017 May 3
• 17 citations
  Neurogenetic analysis of childhood disintegrative disorder
  Abha R. Gupta, Alexander Westphal, Daniel Y.-J. Yang, Catherine A.W. Sullivan, Jeffrey Eilbott, Samir Zaidi, Avery C. Voos, Brent C. Vander Wyk, Pam Ventola, Zainulabe...> ;Molecular Autism. 2017 Apr 4
• 36 citations
  Motor Stereotypies: A Pathophysiological Review.
  Zsanett Péter, Melody E. Oliphant, Thomas V. Fernandez> ;Frontiers in Neuroscience. 2017 Mar 29
• 26 citations
  Pre- and perinatal complications in relation to Tourette syndrome and co-occurring obsessive-compulsive disorder and attention-deficit/hyperactivity disorder
  Mohamed Abdulkadir, Jay A. Tischfield, Robert A. King, Thomas V. Fernandez, Lawrence W. Brown, Keun-Ah Cheon, Barbara J. Coffey, Sebastian F T M de Bruijn, Lonneke Elz...> ;Journal of Psychiatric Research. 2016 Nov 1
• 2 citations
  Prenatal and Perinatal Risk Factors and the Promise of Birth Cohort Studies: Origins of Obsessive-Compulsive Disorder
  Thomas V. Fernandez, James F. Leckman> ;JAMA Psychiatry. 2016 Nov 1
• 1 citations
  The Origins of Tourette Syndrome: Prenatal Risk Factors and the Promise of Birth Cohort Studies
  James F. Leckman, Thomas V. Fernandez> ;Journal of the American Academy of Child and Adolescent Psychiatry. 2016 Sep 1
• 43 citations
  Whole-exome sequencing in obsessive-compulsive disorder identifies rare mutations in immunological and neurodevelopmental pathways.
  Carolina Cappi, Helena Brentani, Leandro Lima, Stephen Sanders, Gwyneth Zai, B J Diniz, Viviane Neri de Souza Reis, Ana Gabriela Hounie, M Conceição do Rosário, Daniel...> ;Translational Psychiatry. 2016 Mar 29
• 132 citations
  Transcriptome Analysis of the Human Striatum in Tourette Syndrome
  Jessica B. Lennington, Gianfilippo Coppola, Yuko Kataoka-Sasaki, Thomas V. Fernandez, Dean Palejev, Yifan Li, Anita Huttner, Mihovil Pletikos, Nenad Sestan, James F. L...> ;Biological Psychiatry. 2016 Mar 1
• 1 citations
  What Makes You Tic? A New Lead in Tourette Syndrome Genetics
  Thomas V. Fernandez> ;Biological Psychiatry. 2016 Mar 1
• 150 citations
  Modeling non-syndromic autism and the impact of TRPC6 disruption in human neurons
  Karina Griesi-Oliveira, Allan Acab, Abha R. Gupta, Daniele Yumi Sunaga, Thanathom Chailangkarn, Xavier Nicol, Yanelli Nunez, Michael F. Walker, John D. Murdoch, Stephe...> ;Molecular Psychiatry. 2015 Nov 1
• 4 citations
  Tourette Syndrome: Bridging the Gap between Genetics and Biology
  Petra Richer, Thomas V. Fernandez> ;Molecular Neuropsychiatry. 2015 Sep 4
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Journal Articles

• Investigation of Previously Implicated Genetic Variants in Chronic Tic Disorders: A Transmission Disequilibrium Test Approach  
  Barbara J Coffey, Donald L Gilbert, Lawrence W Brown, Dorothy E Grice, Thomas V Fernandez, Samuel Kuperman, Samuel H Zinner, European Archives of Psychiatry and Clinical Neuroscience
• Transcranial Magnetic Stimulation of Wernicke’s and right homologous sites to curtail “voices”: A randomized trial.  
  Hoffman RE, Wu K, Pittman B, Cahill JD, Hawkins KA, Fernandez T, Hannestad J, Biological Psychiatry, 1/1/2013
• Rare copy number variants in Tourette syndrome disrupt genes in histaminergic pathways and overlap with autism.  
  Fernandez TV, Sanders SJ, Yurkiewicz IR, et al., Biological Psychiatry, 1/1/2012
• Genome-wide association study of Tourette syndrome.  
  Scharf JM, Yu D, Matthews CA, Neale BM, et al., Molecular Psychiatry, 1/1/2012
• Elevated functional connectivity along a corticostriatal loop and the mechanism of auditory/verbal hallucinations in patients with schizophrenia.  
  Hoffman RE, Fernandez T, Pittman B, Hampson M, Biological Psychiatry, 1/1/2011
• Multiple recurrent de novo copy number variations (CNVs), including duplications of the 7q11.23 Williams-Buren syndrome region, are strongly associated with autism.  
  Sanders SJ, Ercan-Sencicek AG, Hus V, et al., Neuron, 1/1/2011
• 3p deletion and (skewed) literature review (reply).  
  Fernandez TV, State MW, Davalos-Rodriguez NO., American Journal of Medical Genetics, 1/1/2010
• L-histidine decarboxylase and Tourette’s syndrome.  
  Ercan-Sencicek AG, Stillman AA, etl., New England Journal of Medicine, 1/1/2010
• Molecular characterization of a patient with 3p deletion syndrome and a review of the literature.  
  Fernandez TV, et al., American Journal of Medical Genetics, 1/1/2008
• Disruption of contactin 4 (CNTN4) results in developmental delay and other features of 3p deletion syndrome.  
  Fernandez T, Morgan T, Davis N, Klin A, Morris A, Farhi A, Lifton RP, State MW, American Journal of Human Genetics, 1/1/2004
• Genetics and Genomics of Neurobehavioral Disorders.  
  Fernandez TV, State MW, Journal of the American Academy of Child and Adolescent Psychiatry, 1/1/2004
• Premorbid speech and language impairments in childhood-onset schizophrenia:association with risk factors.  
  Nicolson R, Lenane M, Singaracharlu S, Malaspina D, Giedd JN, Hamburger SD, Gochman P, Bedwell J, Thaker GK, Fernandez T, Wudarsky M, Hommer DW, Rapoport JL, American Journal of Psychiatry, 1/1/2000
• Lessons from childhood-onset schizophrenia.  
  Nicolson R, Lenane M, Hamburger SD, Fernandez T, Bedwell J, Rapoport JL, Brain Research Reviews, 1/1/2000
• Clinical and neurobiological correlates of cytogenetic abnormalities in childhood-onset schizophrenia.  
  Nicolson R, Giedd JN, Lenane M, Hamburger S, Singaracharlu S, Bedwell J, Fernandez T, Thaker GK, Malaspina D, Rapoport JL, American Journal of Psychiatry, 1/1/1999
• Obstetrical complications and childhood-onset schizophrenia.  
  Nicolson R, Malaspina D, Giedd JN, Hamburger S, Lenane M, Bedwell J, Fernandez T, Berman A, Susser E, Rapoport JL, American Journal of Psychiatry, 1/1/1999
• Childhood-onset schizophrenia: progressive brain changes during adolescence.  
  Giedd JN, Jeffries NO, Blumenthal J, Castellanos FX, Vaituzis AC, Fernandez T, Hamburger SD, Liu H, Nelson J, Bedwell J, Tran L, Lenane M, Nicolson R, Rapoport JL, Biological Psychiatry, 1/1/1999
• Apolipoprotein E alleles in childhood-onset schizophrenia.  
  Fernandez T, Yan WL, Hamburger S, Rapoport JL, Saunders AM, Schapiro M, Ginns EI, Sidransky E, American Journal of Medical Genetics: Neuropsychiatric Genetics, 1/1/1999
• Progressive cortical change during adolescence in childhood-onset schizophrenia. A longitudinal magnetic resonance imaging study.  
  Rapoport JL, Giedd JN, Blumenthal J, Hamburger S, Jeffries N, Fernandez T, Nicolson R, Bedwell J, Lenane M, Zijdenbos A, Paus T, Evans A, Archives of General Psychiatry, 1/1/1999
• Functional differentiation along the anterior-posterior axis of the hippocampus in monkeys.  
  Colombo M, Fernandez T, Nakamura K, Gross CG, Neurophysiology, 1/1/1998
• Brief report: association of sex chromosome anomalies with childhood-onset psychotic disorders.  
  Kumra S, Wiggs E, Krasnewich D, Meck J, Smith A, Bedwell J, Fernandez T, Jacobsen L, Lenane M, Rapoport J, Journal of the American Academy of Child and Adolescent Psychiatry, 1/1/1998
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Books/Book Chapters

• Lewis’s Child and Adolescent Psychiatry: A Comprehensive Textbook 
  Chapter: Assessing Risk: Gene Discovery In Child Psychiatric Disorders. 
  Fernandez TV, State MWEditors: Martin A, Volkmar FR.Lippincott Williams & Wilkins, Philadelphia, PAEdition 4th,2007

Abstracts/Posters

• Searching for the genes of Tourette’s: The Tourette International Collaborative Genetics (TIC Genetics) Study.
  Heiman GA, Fernandez TV, Hoekstra PJ, Dietrich A, king RA, State MW, Tischfield JA, and the TIC Genetics Team, Annual Meeting of the American Society of Human Genetics., 1/1/2012
• Rare Structural and Sequence Variation in Tourette Syndrome and Autism.
  Fernandez TV, 1st Joint Meeting of the European Network for the Study of Gilles de la Tourette Syndrome (EUNetGTS), 12/14/2011
• Rare copy number variants in Tourette syndrome disrupt genes in histaminergic pathways and overlap with autism.
  Fernandez TV, Sanders SJ, Song Y, Leckman JF, King RA, Gilbert DL, Heiman GA, Tischfield JA, Hoekstra PJ, State MW, American Academy of Child and Adolescent Psychiatry Scientific Proceedings, 1/1/2011
• Rare copy number variants in Tourette syndrome disrupt genes in histaminergic pathways and overlap with autism.
  Fernandez TV, Sanders SJ, Song Y, Leckman JF, King RA, Gilbert DL, Heiman GA, Tischfield JA, Hoekstra PJ, State MW, 50th Annual Meeting of the American College of Neuropsychopharmacology, 1/1/2011
• Elevated functional connectivity in a corticostriatal loop and the mechanism of auditory/verbal hallucinations in patients with schizophrenia.
  Hoffman RE, Fernandez T, Pittman B, Hampson M, Schizophrenia Bulletin, 1/1/2009
• Genetic Investigation of Complex Motor Stereotypies.
  Fernandez T, Sanders S, Mason C, Singer H, Hakonarson H, State MW, American Academy of Child and Adolescent Psychiatry Scientific Proceedings, 1/1/2009
• Stereotactically positioned rTMS delivered to optimized Wernicke’s and right superior temporal sites for auditory/verbal hallucinations.
  Hoffman RE, Wu K, Fulbright R, Buchanan R, Fernandez T, Hawkins KA, Constable T, Hampson M, Biological Psychiatry, 1/1/2008
• Screening autism candidate genes based on a balanced translocation.
  Fernandez T, Klin A, Davis N, Koenig K, State M, American Academy of Child and Adolescent Psychiatry Scientific Proceedings, 1/1/2007
• Characterization of contactin 4, a gene involved in mental retardation.
  State MW, Kwan K, Stillman A, Fernandez T, Morgan T, Davis N, Sestan N, American Academy of Child and Adolescent Psychiatry Scientific Proceedings, 1/1/2004
• Analysis of a balanced (4;11) translocation in three autistic siblings.
  Fernandez T, Klin A, Davis N, Koenig K, Farhi A, Volkmar F, State M, American Academy of Child and Adolescent Psychiatry Scientific Proceedings, 1/1/2004
• Premorbid speech and language impairments in childhood-onset schizophrenia: association with risk factors.
  Nicholson R, Lenane M, Singaracharlu S, Bedwell J, Giedd JN, Hamburger SD, Thaker GK, Malaspina D, Fernandez T, Wudarsky M, Hommer DW, Rapoport JL, Schizophrenia Research, 1/1/2000
• Smooth pursuit eye tracking in the relatives of patients with childhood-onset schizophrenia.
  Nicolson R, Hommer D, Thaker G, Brown M, Bedwell J, Lenane M, Fernandez T, Rapoport JL, Schizophrenia Research, 1/1/1999
• Premorbid impairments in childhood-onset schizophrenia: association with risk factors.
  Nicolson R, Singaracharlu S, Lenane M, Giedd JN, Hamburger SD, Bedwell J, Fernandez T, Rapoport JL, Biological Psychiatry, 1/1/1999
• Obstetrical complications in childhood-onset schizophrenia.
  Nicolson R, Giedd J, Malaspina D, Lenane M, Fernandez T, Bedwell J, Berman A, Susser E, Rapoport JL, Schizophrenia Research, 1/1/1999
• Lack of an association between dopamine transporter (DAT1) and ADHD.
  Lewczyk CM, Fernandez T, Castellanos FX, Koprivica V, Kashani A, Tayebi N, Ginns EI, Rapoport JL, Sidransky E, Biological Psychiatry, 1/1/1999
• Lack of an association between dopamine transporter (DAT1) & ADHD.
  Castellanos FX, Lewczyk CM, Fernandez T, Koprivica V, Kashani A, Tayebi N, Ginns EI, Rapoport JL, Sidransky E, Molecular Psychiatry, 1/1/1999
• HLA alleles in attention-deficit hyperactivity disorder.
  Fernandez T, Lewczyk CM, Castellanos FX, Simonis T, Jacobsen LK, Rapoport JL, Biological Psychiatry, 1/1/1999
• Functional differentiation along the anterior-posterior axis of the hippocampus in monkeys.
  Colombo M, Fernandez T, Nakamura K, Gross CG, European Journal of Neuroscience, 1/1/1998
• Clinical and biological correlates of cytogenetic abnormalities in childhood-onset psychosis.
  Nicolson R, Kumra S, Giedd J, Fernandez T, Bedwell J, Lenane M, Rapoport JL, Biological Psychiatry, 1/1/1998
• A comparison of bimodal, visual-tactile neurons in parietal area 7b and ventral premotor cortex of the monkey brain.
  Graziano MSA, Gross CG, Fernandez TV, Society for Neuroscience Abstracts, 1/1/1996
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Lectures

• Genomic Investigations of Tourette Disorder. 
  Annual Meeting for the European Society for the Study of Tourette Syndrome / COST International Conf - 4/26/2013
• From Bedside to Bench: Translational Clinical Science and Tourette Syndrome. 
  Yale Child Study Center Grand Rounds. New Haven, CT. - 1/15/2013
• Previews from the Pipeline: A Data Blitz Featuring Early Career Investigators. 
  American Academy of Child and Adolescent Psychiatry 59th Annual Meeting. San Francisco, CA. - 10/24/2012
• New findings about the Genetics of Tourette Syndrome. 
  5/22/2012
• Update on the Genetics of Tourette Syndrome. 
  Tourette Syndrome Association National Conference. Arlington, VA - 4/20/2012
• Detecting Rare Structural Variants in Neuropsychiatric Disorders. 
  Columbia University Seminar in Genetic Epidemiology. New York, NY. - 2/9/2012
• Genetic Variation in Childhood Movement Disorders. 
  Yale Child Study Center Grand Rounds. New Haven, CT. - 3/15/2011
• Lost In Translation: Challenges in Linking Basic Science with Clinical Practice in Psychiatry. 
  European Research Training Seminar in Child and Adolescent Psychiatry. Siena, Italy. - 11/21/2010
• Genetic Variation in Tourette Syndrome. 
  Yale Department of Psychiatry Grand Rounds. New Haven, CT. - 6/4/2010
• Genetics in Autism Spectrum Disorders: Obstacles and Promising Alternatives for the Future 
  13th International Congress of the European Society of Child & Adolescent Psychiatry. Florence, Ital - 8/25/2007
• The Gene Hunter. 
  Annual meeting of the Donald J. Cohen Medical Student Training Program. Harvard Medical School, Bost - 1/27/2007
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