ThomasDavidGeppertMD

PubMed

• 103 citations
  Abetimus sodium for renal flare in systemic lupus erythematosus: Results of a randomized, controlled phase III trial
  Mario H. Cardiel, James A. Tumlin, Richard Furie, Daniel J. Wallace, Tenshang Joh, Matthew D. Linnik, Micha Abeles, Jacob A. Aelion, Gerald B. Appel, Cynthia Aranow, S...> ;Arthritis and Rheumatism. 2008 Aug 1
• 149 citations
  Relationship between anti-double-stranded DNA antibodies and exacerbation of renal disease in patients with systemic lupus erythematosus.
  Matthew D. Linnik, Jay Z. Hu, Kenneth R. Heilbrunn, Vibeke Strand, Frank Hurley, Tenshang Joh, D. Alarcón-Segovia, Gerald B. Appel, Cynthia Aranow, Stanley P. Ballou, ...> ;Arthritis and Rheumatism. 2005 Apr 1
• 21 citations
  The Cytoplasmic and the Transmembrane Domains Are Not Sufficient for Class I MHC Signal Transduction
  Hanan Gur, Thomas D. Geppert, Mary C. Wacholtz, Peter E. Lipsky> ;Cellular Immunology. 1999 Feb 1
• 73 citations
  TNF Receptor-Associated Factor-3 Signaling Mediates Activation of p38 and Jun N-Terminal Kinase, Cytokine Secretion, and Ig Production Following Ligation of CD40 on Hu...
  Amrie C. Grammer, Jennifer L. Swantek, Richard D. McFarland, Yasushi Miura, Thomas D. Geppert, Peter E. Lipsky> ;Journal of Immunology. 1998 Aug 1
• 428 citations
  Jun N-terminal kinase/stress-activated protein kinase (JNK/SAPK) is required for lipopolysaccharide stimulation of tumor necrosis factor alpha (TNF-alpha) translation:...
  Jennifer L. Swantek, Melanie H. Cobb, Thomas D. Geppert> ;Molecular and Cellular Biology. 1997 Nov 1
• 14 citations
  STRUCTURAL ANALYSIS OF CLASS I MHC MOLECULES : THE CYTOPLASMIC DOMAIN IS NOT REQUIRED FOR CYTOSKELETAL ASSOCIATION, AGGREGATION AND INTERNALIZATION
  Hanan Gur, Thomas D. Geppert, Peter E. Lipsky> ;Molecular Immunology. 1997 Feb 1
• 50 citations
  The MEK Kinase Activity of the Catalytic Domain of RAF-1 Is Regulated Independently of Ras Binding in T Cells
  Charles E. Whitehurst, Hajime Owaki, Joseph T. Bruder, Ulf R. Rapp, Thomas D. Geppert> ;The Journal of Biological Chemistry. 1995 Mar 10
• 203 citations
  Lipopolysaccharide Signals Activation of Tumor Necrosis Factor Biosynthesis Through the Ras/Raf-1/MEK/MAPK Pathway
  Thomas D. Geppert, Charles E. Whitehurst, Patricia A. Thompson, Bruce Beutler> ;Molecular Medicine. 1994 Nov 1
• 196 citations
  A requirement for extracellular signal-regulated kinase (ERK) function in the activation of AP-1 by Ha-Ras, phorbol 12-myristate 13-acetate, and serum
  Jeffrey A. Frost, Thomas D. Geppert, Melanie H. Cobb, James R. Feramisco> ;Proceedings of the National Academy of Sciences of the United States of America. 1994 Apr 26
• 71 citations
  Raf-1 is required for T cell IL2 production.
  Hajime Owaki, R. Varma, B. Gillis, Joseph T. Bruder, Ulf R. Rapp, Laurie S. Davis, Thomas D. Geppert> ;The EMBO Journal. 1993 Nov 1
• 441 citations
  Regulation and properties of extracellular signal-regulated protein kinases 1 and 2 in vitro
  David J. Robbins, Erzhen Zhen, Hajime Owaki, Colleen A. Vanderbilt, Douglas Ebert, Thomas D. Geppert, Melanie H. Cobb> ;The Journal of Biological Chemistry. 1993 Mar 5
• 8 citations
  Comparison of the capacity of murine and human class I MHC molecules to stimulate T cell activation.
  Hanan Gur, Mary C. Wacholtz, Wen-Rong Lie, Peter E. Lipsky, Thomas D. Geppert> ;Cellular Immunology. 1992 Oct 15
• 20 citations
  Engagement of class I major histocompatibility complex molecules by cell surface CD8 delivers an activation signal.
  Thomas D. Geppert, Hoan Nguyen, Peter E. Lipsky> ;European Journal of Immunology. 1992 Jun 1
• 83 citations
  Extracellular signal-regulated kinases in T cells. Anti-CD3 and 4 beta-phorbol 12-myristate 13-acetate-induced phosphorylation and activation.
  Charles E. Whitehurst, Teri G. Boulton, Melanie H. Cobb, Thomas D. Geppert> ;Journal of Immunology. 1992 May 15
• 8 citations
  Modulatory effect of aggregating the CD3 molecular complex on T cell activation.
  Hanan Gur, Mary C. Wacholtz, Laurie S. Davis, Thomas D. Geppert, Peter E. Lipsky> ;Cellular Immunology. 1992 Mar 1
• 47 citations
  Extracellular signal-regulated kinases in T cells: Characterization of human ERK1 and ERK2 cDNAs
  Hajime Owaki, Robert S. Makar, Teri G. Boulton, Melanie H. Cobb, Thomas D. Geppert> ;Biochemical and Biophysical Research Communications. 1992 Feb 14
• 70 citations
  Association of various T cell-surface molecules with the cytoskeleton. Effect of cross-linking and activation.
  Thomas D. Geppert, Peter E. Lipsky> ;Journal of Immunology. 1991 May 15
• 12 citations
  Immobilized anti-CD3-induced T cell growth: comparison of the frequency of responding cells within various T cell subsets.
  Thomas D. Geppert, Peter E. Lipsky> ;Cellular Immunology. 1991 Mar 1
• 7 citations
  Treatment of systemic sclerosis with antithymocyte globulin.
  Edward P. Balaban, Scott Zashin, Thomas D. Geppert, Peter E. Lipsky, Richard M. Condie> ;Arthritis and Rheumatism. 1991 Feb 1
• 14 citations
  Regulatory role of microfilaments in the induction of T4 cell proliferation and interleukin 2 production.
  Thomas D. Geppert, Peter E. Lipsky> ;Cellular Immunology. 1990 Nov 1
• 47 citations
  Analysis of T cell signaling by class I MHC molecules: the cytoplasmic domain is not required for signal transduction.
  Hanan Gur, Fouad A.K. El-Zaatari, Thomas D. Geppert, Mary C. Wacholtz, Joel D. Taurog, Peter E. Lipsky> ;The Journal of Experimental Medicine. 1990 Oct 1
• 141 citations
  Accessory cell signals involved in T-cell activation.
  Thomas D. Geppert, Laurie S. Davis, Hanan Gur, Mary C. Wacholtz, Peter E. Lipsky> ;Immunological Reviews. 1990 Oct 1
• 7 citations
  Precursor frequency of human T4 cells responding to stimulation through the CD3 molecular complex: Role of various cytokines in promoting growth and IL2 production☆
  Jack B. Vine, Thomas D. Geppert, Peter E. Lipsky> ;Cellular Immunology. 1989 Dec 1
• 59 citations
  Activation of human T cell clones and Jurkat cells by cross-linking class I MHC molecules.
  Thomas D. Geppert, Mary C. Wacholtz, S. S. Patel, E Lightfoot, Peter E. Lipsky> ;Journal of Immunology. 1989 Jun 1
• 8 citations
  T4 cell activation by immobilized phytohemagglutinin: differential capacity to induce IL-2 responsiveness and IL-2 production.
  J B Vine, Thomas D. Geppert, Peter E. Lipsky> ;Journal of Immunology. 1988 Oct 15
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