Thomas Maddox MD MSc

PubMed

• CYP2C19 Polymorphisms and Clinical Outcomes Following Percutaneous Coronary Intervention in the Million Veteran Program.
  Catherine Chanfreau-Coffinier, Kevin A Friede, Mary E Plomondon, Kyung Min Lee, Zhenyu Lu
  Clinical Pharmacology and Therapeutics. 2025-10-01
• Design and methods of the AUTOMATED-WCT trial: evaluating machine learning-based ECG support for WCT interpretation.
  Adam M May, Sarah LoCoco, Krasimira M Mikhova, Rugheed Ghadban, Phillip S Cuculich
  Current Problems in Cardiology. 2025-09-25
• Sodium-Glucose Cotransporter 2 Inhibitor Use for Heart Failure in US Ambulatory Cardiovascular Care.
  Abdelghani El Rafei, Kensey Gosch, Evan S Manning, Alireza Ghajar, Sridharan Raghavan
  JAMA Cardiology. 2025-09-01

Journal Articles

• Coronary Predictors and Outcomes of Staged Versus One-Time Multivessel Revascularization in Multivessel Coronary Artery Disease: Insights from the VA CART Program  
  Peter T Hu, Stephen W Waldo, Mladen Vidovich, Sunil V Rao, Thomas M Maddox, W Schuyler Jones, ScienceDirect
• Short Communication Electronic Health Records and Outpatient Cardiovascular Disease Care Delivery: Insights from the American College of Cardiology’s PINNACLE India Qu...  
  Thomas M Maddox, Deepak L Bhatt, Salim S Virani, ScienceDirect
• The Implications of Cocaine Use and Associated Behaviors on Adverse Cardiovascular Outcomes Among Veterans: Insights from the VA Clinical Assessment, Reporting, and Tr...  
  Steven M Bradley, Thomas M Maddox, Mladen I Vidovich, Clinical Cardiology
• Longitudinal Risk of Adverse Events in Patients With Acute Kidney Injury After Percutaneous Coronary Intervention: Insights From the National Cardiovascular Data Registry  
  Valle JA, McCoy LA, Maddox TM, Rumsfeld JS, Ho PM, Casserly IP, Nallamothu BK, Roe MT, Tsai TT, Messenger JC., Circ Cardiovasc Interv, 1/1/2017
• Factors associated with rhythm control treatment decisions in patients with atrial fibrillation-Insights from the NCDR PINNACLE registry  
  Gehi AK, Doros G, Glorioso TJ, Grunwald GK, Hsu J, Song Y, Turakhia MP, Turchin A, Virani SS, Maddox TM, Am Heart J., 1/1/2017
• Contemporary Trends in Oral Anticoagulant Prescription in Atrial Fibrillation Patients at Low to Moderate Risk of Stroke After Guideline-Recommended Change in Use of t...  
  Katz DF, Maddox TM, Turakhia M, Gehi A, O'Brien EC, Lubitz SA, Turchin A, Doros G, Lei L, Varosy P, Marzec L, Hsu JC, Circ Cardiovasc Qual Outcomes., 1/1/2017
• Seasonal and circadian variations of acute myocardial infarction: Findings from the Get With The Guidelines-Coronary Artery Disease (GWTG-CAD) program  
  Nagarajan V, Fonarow GC, Ju C, Pencina M, Laskey WK, Maddox TM, Hernandez A, Bhatt DL., Am Heart J., 1/1/2017
• Applying Clinical Research to Clinical Practice: The NCDR Research to Practice Initiative  
  Maddox TM, Yeh RW., Cardiology, 1/1/2017
• Big Data Analytics to Improve Cardiovascular Care: Promise and Challenges  
  John S Rumsfeld, Thomas M Maddox, Nature
• Multiple differences between patients who initiate fish oil supplementation post-myocardial infarction and those who do not: The TRIUMPH Study  
  Harris WS, Kennedy KF, Maddox TM, Kutty S, Spertus JA, Nutr Res., 1/1/2016
• Integrating Motivational Interviewing Into a Home Telehealth Program for Veterans With Posttraumatic Stress Disorder Who Smoke: A Randomized Controlled Trial  
  Battaglia C, Peterson J, Whitfield E, Min SJ, Benson SL, Maddox TM, Prochazka AV., J Clin Psychol, 1/1/2016
• Modern Management Practices and Hospital Admissions  
  McConnell KJ, Lindrooth RC, Wholey DR, Maddox TM, Bloom N, Health Econ, 1/1/2016
• Big Data Analytics To Improve Cardiovascular Quality and Outcomes of Care: Promise and Challenges  
  Rumsfeld JR, Joynt KE, Maddox TM., Nature Reviews Cardiology., 1/1/2016
• Post-Discharge Bleeding after Percutaneous Coronary Intervention and Subsequent Mortality and Myocardial Infarction: Insights from the HMO Research Network-Stent Registry  
  Valle JA, Shetterly S, Maddox TM, Ho PM, Bradley SM, Sandhu A, Magid D, Tsai TT., Circ Cardiovasc Interv, 1/1/2016
• Characteristics and In-Hospital Outcomes of Peripartum Cardiomyopathy Diagnosed During Delivery in the United States From the Nationwide Inpatient Sample (NIS) Database  
  Afana M, Brinjikji W, Kao D, Jackson E, Maddox TM, Childers D, Eagle KA, Davis MB., J Card Fail., 1/1/2016
• Coronary angiography and failure to rescue after postoperative myocardial infarction in patients with coronary stents undergoing noncardiac surgery  
  Hollis RH, Holcomb CN, Valle JA, Smith BP, DeRussy AJ, Graham LA, Richman JS, Itani KM, Maddox TM, Hawn MT, Am J Surg., 1/1/2016
• American College of Cardiology (ACC)'s PINNACLE India Quality Improvement Program (PIQIP)-Inception, progress and future direction: A report from the PIQIP Investigators  
  Kalra A, Glusenkamp N, Anderson K, Kalra RN, Kerkar PG, Kumar G, Maddox TM, Oetgen WJ, Virani SS; PIQIP Investigators., Indian Heart J., 1/1/2016
• Targeting Comorbidities in Elderly Patients With Heart Failure: The OPTIMIZE-HFPEF Trial  
  Mentz RJ, Maddox TM, J Card Fail, 1/1/2016
• Should VHA "Make or Buy" Elective Coronary Revascularization Procedures?  
  Barnett PG, Maddox TM, Forum: Translating Research into Quality Healthcare for Veterans. VHA Health Services Research and Development., 1/1/2016
• Worlds Apart: The Hype and Reality of Big Data to Improve Health Care  
  Wasfy JH, Maddox TM, Circ Cardiovasc Qual Outcomes., 1/1/2016
• Characteristics and Outcomes of Women Veterans Undergoing Cardiac Catheterization in the Veterans Affairs Healthcare System: Insights from the VA CART Program  
  Davis MB, Maddox TM, Langner P, Plomondon ME, Rumsfeld JS, Duvernoy CS, Circ Cardiovasc Qual Outcomes., 1/1/2015
• 2014 ACC/AHA/AATS/PCNA/SCAI/STS focused update of the guideline for the diagnosis and management of patients with stable ischemic heart disease: A report of the Americ...  
  Fihn SD, Blankenship JC, Alexander KP, Bittl JA, Byrne JG, Fletcher BJ, Fonarow GC, Lange RA, Levine GN, Maddox TM, Naidu SS, Ohman EM, Smith PK; ACC/AHA Task Force Me..., J Thorac Cardiovasc Surg, 1/1/2015
• Coronary Artery Disease Performance Measures and Statin Use in Patients with Recent Percutaneous Coronary Intervention or Recent Coronary Artery Bypass Grafting (From ...  
  Bandeali SJ, Gosch K, Alam M, Kayani WT, Jneid H, Fiocchi F, Wilson JM, Chan PS, Deswal A, Maddox TM, Virani SS, Am J Cardiol., 1/1/2015
• Variation in Performance Measure Criteria Significantly Affects Cardiology Practice Rankings: Insights from the NCDR (R) PINNACLE Registry (R)  
  Eapen ZJ, Tang F, Jones PG, Maddox TM, Oetgen WJ, Spertus JA, Rumsfeld JS, Heidenreich PA, Peterson ED, Drozda JP Jr., Am Heart J, 1/1/2015
• Differences in anticoagulant therapy prescription in patients with paroxysmal versus persistent atrial fibrillation  
  Hsu JC, Chan PS, Tang F, Maddox TM, Marcus GM, Am J Med, 1/1/2015
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Books/Book Chapters

• Preventive Cardiology: A Companion to Braunwald's Heart Disease 
  Chapter: Chapter 15: The Role of Treatment Adherence in Cardiac Risk Factor Modification. 
  Page 570.0 - 578.0Maddox TM, Ho PMEditors: Blumenthal R, et al..2011
• Atrial Fibrillation: From Bench to Bedside 
  Chapter: Economic Costs Associated with Atrial Fibrillation. 
  Page 13.0 - 26.0Maddox TM, Nash IA, Fuster VEditors: Natale A, Jalife, J.Humana Press, Totowa, NJEdition 1st,2008
•  
  Chapter: Chapter 15: The Role of Treatment Adherence in Cardiac Risk Factor Modification 
  Page 570 - 578Maddox TM, Ho PMBlumenthal R, et al
•  
  Chapter: Economic Costs Associated with Atrial Fibrillation 
  Page 13 - 26Maddox TM, Nash IA, Fuster VEditors: Natale A, Jalife, J.Humana PressEdition 1,
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Abstracts/Posters

• Medication adherence is associated with lower Framingham 10-year CHD risk score.
  Ho PM, Maddox TM, Ross C, Magid DJ, Rumsfeld JS, American Heart Association Quality of Care and Outcomes Research in Cardiovascular Disease & Stroke
• Contemporary Risk of In-Hospital Events in Dialysis Patients Undergoing Percutaneous Coronary Interventions: Insights From the NCDR Cath-PCI Registry.
  Tsai TT, Maddox TM, Roe MT, Dai D, Casserly IP, Ho PM, Messenger JC, Nallamothu BK, Peterson ED, Rumsfeld JS, American Heart Association Scientific Sessions
• In-Hospital Assessment of Hemoglobin A1c in Patients With Diabetes Treated for Myocardial Infarction: Variability Between Hospitals and Relationship With Established Q...
  Stolker JM, McGuire DK, Spertus JA, Inzucchi SE, Rathore SS, Maddox TM, Masoudi FA, Tang F, Jones PG, Kosiborod M, American Heart Association Scientific Sessions
• Initiation of Glucose Lowering Therapy Among Hyperglycemic Patients Without Prior Diabetes Hospitalized for Acute Myocardial Infarction.
  Kosiborod M, Stolker JM, McGuire DK, Inzucchi SE, Rathore SS, Maddox TM, Masoudi FA, Tang F, Jones PG, Spertus JA, European Association for the Study of Diabetes
• Secondary Prevention Therapies among Post-MI Patients with Non-Obstructive CAD: Insights from the TRIUMPH Study.
  Maddox TM, Reid KJ, Ho PM, Tsai T, Spertus JA, Rumsfeld JR, American Heart Association Quality of Care and Outcomes Research in Cardiovascular Disease & Stroke
• Effect of Clopidogrel Use on Death and Myocardial Infarction in Patients Who Receive Drug Eluting Stents for Off Label vs. On Label Indications: Insights from the HMO ...
  Tsai T, Maddox TM, Ho PM, Magid DJ, Go AS, Margolis KS, Shetterly S, Xu S, Powers DJ, American Heart Association Quality of Care and Outcomes Research in Cardiovascular Disease & Stroke
• Impact of Clopidogrel on Death, Myocardial Infarction and Bleeding in Patients Who Receive Drug-Eluting Stents: Insights from the HMO Research Network- Stent Registry ...
  Tsai T, Maddox TM, Ho PM, Magid DJ, Go AS, Margolis KS, Shetterly S, Xu S, Powers DJ, American Heart Association Quality of Care and Outcomes Research in Cardiovascular Disease & Stroke
• Impaired Heart Rate Recovery is Associated with New-Onset Atrial Fibrillation.
  Maddox TM, Ross C, Ho PM, Magid DJ, Rumsfeld JS, American College of Cardiology Scientific Sessions
• Clopidogrel Use among Medically-Managed NSTEMI Patients: Insights from the NCDR ACTION-GWTG Registry.
  Maddox TM, Ho PM, Wang TY, Ou F, Tsai T, Wiviott SD, Rumsfeld JS, American College of Cardiology Scientific Sessions
• Associations between Clinical Encounters and Statin Adherence.
  Maddox TM, Williams E, Ho PM, Steiner JF, Rumsfeld JS, American College of Cardiology Scientific Sessions
• Clustering of adverse events after stopping clopidogrel: Using registry data to address medication effectiveness.
  Ho PM, Maddox TM, Wang L, Jesse R, Fihn SD, Rumsfeld JS, U.S. Department of Veterans Affairs Quality Enhancement Research Initiative National Conference
• Proton Pump Inhibitors May Attenuate the Benefits of Clopidogrel among ACS Patients: Empirical Evidence from 3,311 ACS Patients.
  Ho PM, Maddox TM, Wang L, Fihn SD, Jesse RL, Peterson ED, Rumsfeld JS, American Heart Association Scientific Sessions
• The Costs of Healthcare Associated with Medication Non-Adherence.
  Ho PM, Maddox TM, Shetterly SM, Rumsfeld JS, Magid DJ, American Heart Association Quality of Care and Outcomes Research in Cardiovascular Disease & Stroke
• Achieving longitudinal target blood pressure after acute myocardial infarction.
  Wang TY, Reid KJ, Ho PM, Maddox TM, Chan P, Rumsfeld JR, Peterson ED, American Heart Association Scientific Sessions
• Accurate identification of hypertension (HTN) from administrative clinical databases.
  Shetterly SM, Tavel HM, Ho, PM, Maddox TM, Crounse L, Magid DJ, American Heart Association Quality of Care and Outcomes Research in Cardiovascular Disease & Stroke
• Medication non-adherence is associated with a broad range of adverse outcomes in CAD patients.
  Ho PM, Magid DJ Shetterly SM, Olson KL, Maddox TM, Peterson PN, Masoudi FA, Rumsfeld JS, American Heart Association Scientific Sessions
• The Contribution of Depression to Myocardial Infarction Outcomes among Caucasians and African Americans.
  Parashar S, Maddox TM, Reid KJ, Vaccarino V, Spertus JA, Buchanan D, Rumsfeld JS, American Heart Association Scientific Sessions
• Factors Associated with Statin Adherence after Acute Coronary Syndrome.
  Maddox TM, Plomondon ME, Ho PM, Fihn SJ, Bryson CL, Spertus JA, Rumsfeld JS, American Heart Association Quality of Care and Outcomes Research in Cardiovascular Disease & Stroke
• Predictors of positive nuclear perfusion studies in an ED chest pain unit.
  Maddox TM, Corriel J, Haas D, Duvall WL, Henzlova MJ, American Society of Nuclear Cardiology
• "Stress Only” Tc99m gated MIBI SPECT Imaging: Prognosis of a normal study.
  Chalfoun NT, Flesichut P, Maddox TM, Duvall WL, Henzlova MJ, American Society of Nuclear Cardiology
• Risk Factor Management Post-MI: Adherence and Outcomes.
  Decker CJ, Amin A, Jones P, Maddox TM, Ramesh P, Spertus JA, American Heart Association Quality of Care and Outcomes Research in Cardiovascular Disease & Stroke
• Higher One-Year Mortality in Patients with NSTEMI Compared to Patients with STEMI is Primarily Due to Existing Co-Morbidities.
  Khanal S, Bazari R, Tucciarone M, Reid KJ, Maddox TM, Weintraub WS, Krumholz HM, Cohen DJ, Spertus JA, American Heart Association Quality of Care and Outcomes Research in Cardiovascular Disease & Stroke
• Left Atrial Size Can Identify the Highest Risk Multicenter Automatic Defibrillator Implantation Trial-II Patients For Ventricular Arrhythmic Events.
  Zohlman A, Croft LB, Mehta D, Maddox TM, Goldman ME, American College of Cardiology Scientific Sessions
• Patient knowledge and statin use.
  Maddox TM, Reid KJ, Ho PM, Rumsfeld JS, Weintraub WS, Krumholz HA, Spertus JA, American College of Cardiology Scientific Sessions
• Health Status and Clinical Outcomes after Myocardial Infarction at one Year: A Comparison between Patients Hospitalized with ST-elevation versus non-ST-elevation Myoca...
  Khanal S, Bazari R, Tucciarone M, Maddox TM, Reid KJ, Weintraub WS, Krumholz HA, Spertus JA, American College of Cardiology Scientific Sessions
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Lectures

• Outcomes Research 
  2019 ACC Scientific Session & Expo, New Orleans - 3/16/2019
• Engage @ACC.19 Studio: The 0's and 1s of Digital Health and the Heart — A Primer for the Clinical Cardiologist 
  2019 ACC Scientific Session & Expo, New Orleans - 3/16/2019
• ACC-Talk: Digital Health in Cardiology, Are We There Yet? 
  2019 ACC Scientific Session & Expo, New Orleans - 3/16/2019
• State of the VA CART Program 
  1/1/2017
• Data Innovations in Patient-Centered Care: The VA CART Example 
  San Diego, CA - 1/1/2017
• Expert Insights into the Top Questions Regarding Anticoagulation for Atrial Fibrillation 
  Division of Cardiology, University of Colorado School of Medicine - 1/1/2016
• Learning Healthcare Systems and High-Value Care: Examples from Cardiology 
  Seattle, WA, 2016; Virginia Mason Medical Center, Seattle, WA, 2016 - 1/1/2016
• Nonobstructive CAD and Risk of MI 
  VA Eastern Colorado Health Care System, Denver CO - 1/1/2015
• Learning Healthcare Systems and the VA CART Program 
  Mayo Clinic, Rochester, MN, 2015; Salt Lake City, UT, 2015 - 1/1/2015
• Evolving Concepts on Lipid Management: Debated Implications of the 2013 Guidelines - Are PCSK9 Inhibitors Poised For Breakthrough? 
  Mumbai, India - 1/1/2015
• Evolving Concepts on Hypertension: Debated Implications of the 2014 JNC 8 Recommendations 
  Mumbai, India - 1/1/2015
• ACS and Lipid Management 
  Mumbai, India; Kochi, India; Kathmandu, Nepal; Dhaka, Bangladesh - 1/1/2015
• Clinical Registries, Quality Improvement, and Outcomes Research 
  Mendoza, Argentina, 2014; Beijing, China, 2014 - 1/1/2014
• Preventing Avoidable Readmissions: Strategies to Optimize ACS Transitions of Care 
  ACH Community Memorial Hospital, Missouri Valley, IA - 1/1/2014
• Implications of the 2013 ACC/AHA Cholesterol Guidelines for Adults in Contemporary Cardiovascular Practice: Insights from the NCDR(R) PINNACLE Registry(R) 
  1/1/2014
• Non-Obstructive Coronary Artery Disease Is Not Benign: Insights from the VA CART Program on the Association between Non-Obstructive Disease and Cardiac Events 
  1/1/2014
• Expert Insights into the Top Ten Questions Regarding Anti-Platelet Therapy in Contemporary Cardiovascular Practice 
  Division of Cardiology, University of Colorado School of Medicine - 1/1/2014
• Optimizing the Quality of Perioperative Care: How Do We Bridge the Evidence Gaps? 
  1/1/2013
• How to Set Up An Acute Coronary Syndrome Performance Improvement Program 
  1/1/2013
• Transforming Health Care through CV Registries: The VA CART Program 
  1/1/2012
• Measuring and Optimizing Quality in your Outpatient Practice: The PINNACLE Registry 
  1/1/2012
• Getting Access to Data: Successful Examples from the NCDR 
  1/1/2012
• The VA CART Program 
  1/1/2012
• CT Calcium Scoring 
  University of Colorado School of Medicine - 1/1/2012
• Learning Health Care Systems and the VA CART Program 
  Learning Health Care Systems and the VA CART Program - 1/1/2012
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Other

• Novel Oral Anticoagulants for Stroke Prevention 
  VuMedi Webinar
  1/1/2016
• Audio Presentation, "Nonobstructive CAD and Risk of MI" 
  New England Journal of Medicine JournalWatch
  1/1/2014
• Dual Anti-Platelet Therapy in Stable Ischemic Heart Disease: Striking a Delicate Balance 
  Sandhu A, Valle J, Thompson LE, Maddox TM., Cardiology Blog. American College of Cardiology.
  http://www.acc.org/latest-in-cardiology/articles/2015/10/08/09/50/dual-anti-platelet-therapy-in-stable-ischemic-heart-disease?w_nav=TI
  1/20/2015