ThomasWilliamsMcLeanMD

Pediatric Hematology & Oncology • Winston Salem, NC

Associate Professor of Pediatrics, Wake Forest University

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Office
Medical Center Blvd
Winston Salem, NC 27157
Phone+1 336-716-4085

Fax+1 336-716-3010
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Education & Training

Children's Hospital/Boston Medical CenterFellowship, Pediatric Hematology/Oncology, 1994 - 1997
Children's Hospital of PhiladelphiaResidency, Pediatrics, 1990 - 1993
Medical University of South CarolinaClass of 1990

Certifications & Licensure

NC State Medical License 1998 - 2024
FL State Medical License 2021 - 2023
PA State Medical License 1992 - 1994
American Board of Pediatrics Pediatrics
American Board of Pediatrics Pediatric Hematology-Oncology

Awards, Honors, & Recognition

America's Top Doctors Castle Connolly, 2012-2017
America's Top Doctors for Cancer Castle Connolly, 2011-2013
Top MD Consumers Checkbook

Clinical Trials

Genetic Analysis in Identifying Late-Occurring Complications in Childhood Cancer Survivors Start of enrollment: 2004 Mar 25
Recruiting
Acupressure in Preventing Nausea and Vomiting in Young Cancer Patients Receiving Chemotherapy Start of enrollment: 2005 Apr 01
Completed
Not Applicable
Glutamic Acid in Reducing Nerve Damage Caused by Vincristine in Young Patients With Cancer Start of enrollment: 2007 May 01
Completed
Phase 3
Neuropsychological and Behavioral Testing in Younger Patients With Cancer Start of enrollment: 2009 Feb 27
Recruiting
Collecting and Storing Malignant, Borderline Malignant Neoplasms, and Related Samples From Young Patients With Cancer Start of enrollment: 2003 Oct 13
Completed
Study of Kidney Tumors in Younger Patients Start of enrollment: 2006 Feb 27
Recruiting
Collecting and Storing Biological Samples From Patients With Ewing Sarcoma Start of enrollment: 2008 Feb 04
Completed
Biomarkers in Tumor Tissue Samples From Patients With Newly Diagnosed Neuroblastoma or Ganglioneuroblastoma Start of enrollment: 2000 Nov 06
Recruiting
Collecting and Storing Tissue, Blood, and Bone Marrow Samples From Patients With Rhabdomyosarcoma or Other Soft Tissue Sarcoma Start of enrollment: 1999 Mar 15
Completed
Collecting and Storing Blood and Brain Tumor Tissue Samples From Children With Brain Tumors Start of enrollment: 2004 Feb 16
Completed
Combination Chemotherapy and Surgery in Treating Young Patients With Wilms Tumor Start of enrollment: 2009 Jul 13
Active, not recruiting
Phase 3
Risk-Based Therapy in Treating Younger Patients With Newly Diagnosed Liver Cancer Start of enrollment: 2009 Sep 14
Active, not recruiting
Phase 3
Maintenance Chemotherapy or Observation Following Induction Chemotherapy and Radiation Therapy in Treating Patients With Newly Diagnosed Ependymoma Start of enrollment: 2010 May 07
Active, not recruiting
Phase 3
Cyproheptadine in Preventing Weight Loss in Children Receiving Chemotherapy for Cancer Start of enrollment: 2010 Jun 01
Terminated
Phase 3
Risk-Based Classification System of Patients With Newly Diagnosed Acute Lymphoblastic Leukemia Start of enrollment: 2010 Aug 09
Completed
Risk-Adapted Chemotherapy in Treating Younger Patients With Newly Diagnosed Standard-Risk Acute Lymphoblastic Leukemia or Localized B-Lineage Lymphoblastic Lymphoma Start of enrollment: 2010 Aug 09
Active, not recruiting
Phase 3
Combination Chemotherapy in Treating Patients With Non-Metastatic Extracranial Ewing Sarcoma Start of enrollment: 2010 Nov 22
Active, not recruiting
Phase 3
Caspofungin Versus Fluconazole in Preventing Invasive Fungal Infections (IFI) in Patients Undergoing Chemotherapy for Acute Myeloid Leukemia Start of enrollment: 2011 Apr 04
Completed
Phase 3
Acupressure in Controlling Nausea in Young Patients Receiving Highly Emetogenic Chemotherapy Start of enrollment: 2011 May 01
Completed
Not Applicable
Levofloxacin in Preventing Infection in Young Patients With Acute Leukemia Receiving Chemotherapy or Undergoing Stem Cell Transplantation Start of enrollment: 2011 Sep 01
Completed
Phase 3
Bortezomib and Sorafenib Tosylate in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia Start of enrollment: 2011 Jun 20
Active, not recruiting
Phase 3
A Phase III Randomized Trial for Newly Diagnosed High Risk B-precursor Acute Lymphoblastic Leukemia (ALL) Testing Clofarabine (IND# 73789, NSC# 606869) in the Very High Risk Stratum Start of enrollment: 2012 Feb 01
Intergroup Trial for Children or Adolescents With B-Cell NHL or B-AL: Evaluation of Rituximab Efficacy and Safety in High Risk Patients Start of enrollment: 2012 Jun 01
Risk-Based Therapy in Treating Younger Patients With Newly Diagnosed Liver Cancer Start of enrollment: 2009 Sep 01
A Study of the Drugs Selumetinib vs. Carboplatin and Vincristine in Patients With Low-Grade Glioma Start of enrollment: 2020 Jan 31
Recruiting
Phase 3
Roles: Principal Investigator
Provider-Focused Intervention for Maximizing HPV Vaccine Uptake in Young Cancer Survivors Start of enrollment: 2021 Feb 01
Recruiting
Not Applicable
Roles: Contact
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Publications & Presentations

PubMed

2 citations
Fertility Preservation Decisional Turning Points for Adolescents and Young Adults With Cancer: Exploring Alignment and Divergence by Race and Ethnicity.
Mollie R Canzona, Karly Murphy, David Victorson, Onengiya Harry, Marla L Clayman, Thomas W McLean, Shannon L Golden, Bonnie Patel, Carla Strom, Denisha Little-Greene, ...> ;JCO Oncology Practice. 2023 Jul 1
5 citations
Infantile Hemangioma: A Current Review.
Kristy S Pahl, Thomas W McLean> ;Journal of Pediatric Hematology/oncology. 2022 Mar 1
1 citations
COVID-19-Related Reduction in Emergency Health Care Utilization Among Febrile Pediatric Oncology Patients.
David E. Kram, Janet A. Tooze, Thomas B. Russell, Thomas W. McLean> ;Journal of Pediatric Hematology/oncology. 2021 Jul 1
Eutectic Mixture of Lidocaine and Prilocaine Decreases Movement and Propofol Requirements for Pediatric Lumbar Puncture During Deep Sedation: A Randomized, Placebo-Con...
Dudley E. Hammon, Katharine Pearsall, Nancy M Smith, Allison S McBride, Andora L Bass, Janet A. Tooze, Thomas W. McLean> ;Journal of Pediatric Hematology/oncology. 2021 Apr 21
15 citations
A conceptual model of fertility concerns among adolescents and young adults with cancer.
Mollie Rose Canzona, David Victorson, Karly M. Murphy, Marla L. Clayman, Bonnie Patel, Nicole Puccinelli-Ortega, Thomas W. McLean, Onengiya Harry, Denisha Little-Green...> ;Psycho-Oncology. 2021 Apr 11
2 citations
Nontranfusional Management of Severe Anemia in an Adolescent Jehovah's Witness Patient.
Mark R. Nazal, Mary Jane Underdown, Lawrence D. Hopkins, Thomas W. McLean> ;The Journal of Adolescent Health. 2021 Mar 10
6 citations
Fertility preservation for pediatric male cancer patients: illustrating contemporary and future options; a case report.
Omar Abdelaal, Nicholas Deebel, Nima Pourhabibi Zarandi, Stanley J. Kogan, Frank C. Marini, Thomas Pranikoff, Kimberly Stogner-Underwood, Thomas W. McLean, Anthony Ata...> ;Translational Andrology and Urology. 2021 Jan 1
6 citations
Adaptive and maladaptive forms of disengagement coping in caregivers of children with chronic illnesses
Christian E. Waugh, Calissa J. Leslie-Miller, Elaine Z. Shing, R. Michael Furr, Chandylen L Nightingale, Thomas W. McLean> ;Stress and Health. 2021 Apr 1
A 6-week-old male infant with persistent leukocytosis.
Ryan Matthews, Thomas W. McLean, David D. Grier, Avinash K. Shetty> ;Paediatrics & Child Health. 2020 Apr 10
9 citations
Hypoalbuminemia in children with cancer treated with chemotherapy
Thomas W. McLean, Ryan Michael Stewart, Thomas Patrick Curley, Mark Young Dewsnup, Sydney Gillian Thomas, Thomas B. Russell, Janet A. Tooze> ;Pediatric Blood & Cancer. 2020 Feb 1
9 citations
Risk factors for chemotherapy-induced nausea in pediatric patients receiving highly emetogenic chemotherapy.
L. Lee Dupuis, Roy N. Tamura, Kara M. Kelly, Jeffrey P. Krischer, Anne-Marie R Langevin, Lu Chen, E. Anders Kolb, Nicole J. Ullrich, Olle Jane Z. Sahler, Eleanor Hende...> ;Pediatric Blood & Cancer. 2019 Apr 1
Surveillance imaging in pediatric melanoma
Thomas W. McLean> ;Pediatric Blood & Cancer. 2019 Feb 1
3 citations
Sudden Cardiac Arrest Due to Hemophagocytic Lymphohistiocytosis in a Child.
Michael C. McCrory, Sophia S. Wang, Avinash K. Shetty, Thomas W. McLean, Patrick E. Lantz, Michael L. Cannon> ;The Journal of Emergency Medicine. 2018 Nov 1
29 citations
Pneumocystis Jirovecii Pneumonia During Sirolimus Therapy for Kaposiform Hemangioendothelioma
Thomas B. Russell, Claire S. Dillingham, Laurence B. Givner, Thomas W. McLean> ;Pediatrics. 2018 Apr 1
14 citations
Acupressure bands do not improve chemotherapy‐induced nausea control in pediatric patients receiving highly emetogenic chemotherapy: A single‐blinded, randomized contr...
L. Lee Dupuis, Kara M. Kelly, Jeffrey P. Krischer, Anne-Marie R Langevin, Roy N. Tamura, Ping Xu, Lu Chen, E. Anders Kolb, Nicole J. Ullrich, Olle Jane Z. Sahler, Elea...> ;Cancer. 2018 Mar 15
32 citations
Experimental testicular tissue banking to generate spermatogenesis in the future: A multidisciplinary team approach.
Hooman Sadri-Ardekani, Thomas W. McLean, Stanley J. Kogan, Joseph Sirintrapun, Kathryn Crowell, Mustafa Q. Yousif, Steve J. Hodges, John K. Petty, Thomas Pranikoff, Le...> ;Methods. 2016 Apr 15
12 citations
Imaging of primary pediatric lymphoma of bone
Kathryn S. Milks, Thomas W. McLean, Evelyn Y. Anthony> ;Pediatric Radiology. 2016 Apr 4
Corrigendum: Mutations in the transcriptional repressor REST predispose to Wilms tumor.
Shazia Mahamdallie, Sandra Hanks, Kristen L. Karlin, Anna Zachariou, Elizabeth R Perdeaux, Elise Ruark, Chad A. Shaw, Alexander Renwick, Emma Ramsay, Shawn Yost, Anna ...> ;Nature Genetics. 2016 Apr 1
50 citations
Mutations in the transcriptional repressor REST predispose to Wilms tumor
Shazia Mahamdallie, Sandra Hanks, Kristen L. Karlin, Anna Zachariou, Elizabeth R Perdeaux, Elise Ruark, Chad A. Shaw, Alexander Renwick, Emma Ramsay, Shawn Yost, Anna ...> ;Nature Genetics. 2015 Dec 1
5 citations
Successful Radiofrequency Ablation for Recurrent Pulmonary Hepatoblastoma.
Charles L. Dunn, John T. Lucas, Hollins P. Clark, Thomas W. McLean> ;Pediatric Blood & Cancer. 2015 Dec 1
154 citations
Pituitary blastoma: a pathognomonic feature of germ-line DICER1 mutations.
Leanne de Kock, Nelly Sabbaghian, François Plourde, Archana Srivastava, Evan Weber, Dorothée Bouron-Dal Soglio, Nancy Hamel, Joon Hyuk Choi, Sung Hye Park, Cheri Deal,...> ;Acta Neuropathologica. 2014 May 20
1 citations
High dose therapy for recurrent Wilms’ tumor
Thomas W. McLean> ;Translational Pediatrics. 2014 Jan 22
5 citations
The Use of a Checklist in a Pediatric Oncology Clinic
Thomas W. McLean, Gina M. White, Abigail F. Bagliani, James Lovato> ;Pediatric Blood & Cancer. 2013 Nov 1
3 citations
Segmental Ulcerated Perineal Hemangioma of Infancy: A Complex Case of PELVIS Syndrome Successfully Treated Using a Multidisciplinary Approach
Shivani B. Kaushik, Shawn G. Kwatra, Thomas W. McLean, Alexander Powers, Anthony J. Atala, Gil Yosipovitch> ;Pediatric Dermatology. 2013 Nov 1
32 citations
A review of contemporary options for medical management of hemangiomas, other vascular tumors, and vascular malformations.
Julie Blatt, Thomas W. McLean, Sharon M. Castellino, Craig N. Burkhart> ;Pharmacology & Therapeutics. 2013 Sep 1
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