ThomasSemradMDMAS

Medical Oncologist Gene Upshaw Tahoe Forest Cancer Center Associate Clinical Professor (WOS) of Hematology/Oncology UC Davis Medical Center

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Office
10121 Pine Ave
Truckee, CA 96161
Phone+1 530-582-6450
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Education & Training

University of California Davis HealthFellowship, Hematology and Medical Oncology, 2007 - 2010
University of California Davis HealthResidency, Internal Medicine, 2004 - 2007
Rush Medical College of Rush University Medical CenterClass of 2004

Certifications & Licensure

CA State Medical License 2005 - 2025
NV State Medical License 2023 - 2025
American Board of Internal Medicine Hematology
American Board of Internal Medicine Medical Oncology

Awards, Honors, & Recognition

CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2012

Clinical Trials

Oxaliplatin, Leucovorin Calcium, and Fluorouracil With or Without Celecoxib in Treating Patients With Stage III Colon Cancer Previously Treated With Surgery Start of enrollment: 2010 Jun 01
Active, not recruiting
Phase 3
Cediranib Maleate With or Without Lenalidomide for the Treatment of Thyroid Cancer Start of enrollment: 2010 Sep 09
Completed
Phase 1, Phase 2
S1201: Combination Chemo for Patients W/Advanced or Metastatic Esophageal, Gastric, or Gastroesophageal Junction Cancer Start of enrollment: 2012 Feb 01
Completed
Phase 2
PROSPECT: Chemotherapy Alone or Chemotherapy Plus Radiation Therapy in Treating Patients With Locally Advanced Rectal Cancer Undergoing Surgery Start of enrollment: 2012 Jun 12
Active, not recruiting
Phase 2, Phase 3
Trebananib With or Without Bevacizumab, Pazopanib Hydrochloride, Sorafenib Tosylate, or Sunitinib Malate in Treating Patients With Advanced Kidney Cancer Start of enrollment: 2012 Aug 01
Completed
Phase 2
Study of Dovitinib and Biomarkers in Advanced Non-Small Cell Lung Cancer or Advanced Colorectal Cancer Start of enrollment: 2013 Feb 01
Completed
Phase 2
SGI-110 in the Treatment of Advanced Hepatocellular Carcinoma (HCC) Start of enrollment: 2012 Dec 01
Completed
Phase 2
S1216, Phase III ADT+TAK-700 vs. ADT+Bicalutamide for Metastatic Prostate Cancer Start of enrollment: 2013 Mar 08
Active, not recruiting
Phase 3
Irinotecan and Alisertib in Treating Patients With Advanced Solid Tumors or Colorectal Cancer Start of enrollment: 2013 Aug 01
Completed
Phase 1
Selumetinib and Cyclosporine in Treating Patients With Advanced Solid Tumors or Advanced or Metastatic Colorectal Cancer Start of enrollment: 2014 Aug 05
Active, not recruiting
Phase 1
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Publications & Presentations

PubMed

1 citations
A phase II study of bevacizumab and temsirolimus in advanced extra-pancreatic neuroendocrine tumors.
Sonia M Abuzakhm, Vineeth Sukrithan, Briant Fruth, Rui Qin, Jonathan Strosberg, Timothy J Hobday, Thomas Semrad, Diane Reidy-Lagunes, Hedy Lee Kindler, George P Kim, J...> ;Endocrine-Related Cancer. 2023 Nov 1
34 citations
Immunotherapy and Targeted Therapy for Advanced Gastroesophageal Cancer: ASCO Guideline.
Manish A Shah, Erin B Kennedy, Ashley E Alarcon-Rozas, Thierry Alcindor, Angela N Bartley, Aubrey Belk Malowany, Nishin A Bhadkamkar, Dana C Deighton, Yelena Janjigian...> ;Journal of Clinical Oncology. 2023 Mar 1
4 citations
A phase I dose escalation, dose expansion and pharmacokinetic trial of gemcitabine and alisertib in advanced solid tumors and pancreatic cancer.
Justin A Chen, Jasmine C Huynh, Chun-Yi Wu, Ai-Ming Yu, Karen Matsukuma, Thomas J Semrad, David R Gandara, Tianhong Li, Jonathan W Riess, Kit Tam, Philip C Mack, Antho...> ;Cancer Chemotherapy and Pharmacology. 2022 Sep 1
5 citations
EGFR High Copy Number Together With High EGFR Protein Expression Predicts Improved Outcome for Cetuximab-based Therapy in Squamous Cell Lung Cancer: Analysis From SWOG...
Fred R. Hirsch, Mary W. Redman, James Moon, Francesco Agustoni, Roy S. Herbst, Thomas J. Semrad, Marileila Varella-Garcia, Christopher J. Rivard, Karen Kelly, David R....> ;Clinical Lung Cancer. 2021 Oct 10
7 citations
Phase 1 study of alisertib (MLN8237) and weekly irinotecan in adults with advanced solid tumors
Thomas J. Semrad, Edward J. Kim, I-Yeh Gong, Tianhong Li, Scott D Christensen, Mili Arora, Jonathan W. Riess, David R. Gandara, Karen Kelly> ;Cancer Chemotherapy and Pharmacology. 2021 May 15
5 citations
Influence of Socioeconomic Status on Incident Medical Conditions in Two-Year Survivors of Adolescent or Young Adult Differentiated Thyroid Cancer
Thomas J. Semrad, Qian Li, Melanie Goldfarb, Alison Semrad, Michael J. Campbell, D. Gregory Farwell, Theresa H.M. Keegan> ;Journal of Adolescent and Young Adult Oncology. 2021 Jan 28
2 citations
Molecular Insights in Transmission of Cancer From an Organ Donor to Four Transplant Recipients.
Chloe E. Atreya, Eric A. Collisson, Meyeon Park, James P. Grenert, Spencer C. Behr, Amalia Gonzalez, Jonathan Chou, Samantha Maisel, Terence W. Friedlander, Chris E. F...> ;Journal of the National Comprehensive Cancer Network. 2020 Nov 2
15 citations
Oxaliplatin-DNA Adducts as Predictive Biomarkers of FOLFOX Response in Colorectal Cancer: A Potential Treatment Optimization Strategy.
Maike Zimmermann, Tao Li, Thomas J. Semrad, Chun Yi Wu, Aiming Yu, George D. Cimino, Michael A. Malfatti, Kurt W. Haack, Kenneth W. Turteltaub, Chong-Xian Pan, May Cho...> ;Molecular Cancer Therapeutics. 2020 Jan 1
43 citations
Role of Treatment Deintensification in the Management of p16+ Oropharyngeal Cancer: ASCO Provisional Clinical Opinion
David J. Adelstein, Nofisat Ismaila, Jamie A. Ku, Barbara Burtness, Paul L. Swiecicki, Loren K. Mell, Jonathan J. Beitler, Neil D. Gross, Christopher U. Jones, Marnie ...> ;Journal of Clinical Oncology. 2019 Apr 25
5 citations
Randomized Phase 2 Study of Trebananib (AMG 386) with or without Continued Anti-Vascular Endothelial Growth Factor Therapy in Patients with Renal Cell Carcinoma Who Ha...
Thomas J. Semrad, Susan Groshen, Chunqiao Luo, Sumanta K. Pal, Ulka N. Vaishampayan, Monika Joshi, David I. Quinn, Philip C. Mack, David R. Gandara, Primo N. Lara> ;Kidney Cancer. 2019 Feb 5
4 citations
Predictors of Neck Reoperation and Mortality After Initial Total Thyroidectomy for Differentiated Thyroid Cancer.
Thomas J. Semrad, Theresa H.M. Keegan, Alison Semrad, Ann Brunson, D. Gregory Farwell> ;Thyroid. 2018 Sep 1
6 citations
A phase I trial of topotecan plus tivantinib in patients with advanced solid tumors.
Stephen V. Liu, Susan Groshen, Karen Kelly, Karen L. Reckamp, Chandra P. Belani, Timothy W. Synold, Amir Goldkorn, Barbara J. Gitlitz, Mihaela C. Cristea, I-Yeh Gong, ...> ;Cancer Chemotherapy and Pharmacology. 2018 Aug 20
11 citations
A phase I trial of escalating doses of cixutumumab (IMC-A12) and sorafenib in the treatment of advanced hepatocellular carcinoma.
Anthony B. El-Khoueiry, Robert T. O'Donnell, Thomas J. Semrad, Philip C. Mack, Suzette Blanchard, Nathan Bahary, Yixing Jiang, Yun Yen, John J. Wright, Helen X. Chen, ...> ;Cancer Chemotherapy and Pharmacology. 2018 Mar 8
13 citations
Significant clinical response to a MEK inhibitor therapy in a patient with metastatic melanoma harboring an RAF1 fusion
Kevin B. Kim, Thomas Semrad, Alexa B. Schrock, Siraj M. Ali, Jeffrey S. Ross, Mark I. Singer, Mohammed Kashani-Sabet> ;JCO Precision Oncology. 2018 Jan 17
7 citations
Molecular Testing for the Treatment of Advanced Colorectal Cancer: An Overview.
Patrick S. Lin, Thomas J. Semrad> ;Methods in Molecular Biology. 2018 Jan 1
58 citations
Cetuximab plus carboplatin and paclitaxel with or without bevacizumab versus carboplatin and paclitaxel with or without bevacizumab in advanced NSCLC (SWOG S0819): a r...
Roy S. Herbst, Mary W. Redman, Edward S. Kim, Thomas J. Semrad, Lyudmila Bazhenova, Gregory A. Masters, Kurt R. Oettel, Perry Guaglianone, Christopher M. Reynolds, Ana...> ;The Lancet. Oncology. 2018 Jan 1
12 citations
Mediating Effect of Postsurgical Chemotherapy on Presence of Dementia and Survival among Patients 65 and Older with Stage III Colon Cancer.
Yingjia Chen, Rosemary D. Cress, Susan L. Stewart, Thomas J. Semrad, Danielle J Harvey, Daniel J. Tencredi, Laurel A. Beckett> ;Cancer Epidemiology, Biomarkers & Prevention. 2017 Oct 1
16 citations
Phase II Study of Dovitinib in Patients Progressing on Anti-Vascular Endothelial Growth Factor Therapy
Thomas J. Semrad, Edward J. Kim, Michael Tanaka, Jacob Sands, Chris Roberts, Rebekah A. Burich, Yu Li, David R. Gandara, Primo N. Lara, Philip C. Mack> ;Cancer Treatment and Research Communications. 2017 Jan 1
7 citations
Are there disparities in the presentation, treatment and outcomes of patients diagnosed with medullary thyroid cancer?-An analysis of 634 patients from the California ...
Christine Cox, Yingjia Chen, Rosemary D. Cress, Alison Semrad, Thomas J. Semrad, Jessica E. Gosnell, Michael J. Campbell> ;Gland Surgery. 2016 Aug 1
4 citations
The Role of Image-guided Radiotherapy in the Treatment of Anorectal Cancer Using Prone Belly-board Positioning.
Jaclyn Miyamoto, A.L. Michaud, Nima K. Harandi, Edward J. Kim, Thomas J. Semrad, Vijay P. Khatri, Jyoti Mayadev, Julian R Perks, Arta M. Monjazeb> ;Anticancer Research. 2016 Jun 1
5 citations
Molecular testing to optimize therapeutic decision making in advanced colorectal cancer.
Thomas J. Semrad, Edward J. Kim> ;Journal of Gastrointestinal Oncology. 2016 Apr 1
11 citations
Disease Control Rate at 8 Weeks Predicts Subsequent Survival in Platinum-Treated Extensive Stage Small-Cell Lung Cancer: Results From the Southwest Oncology Group (SWO...
Primo N. Lara, James Moon, Mary W. Redman, Thomas J. Semrad, Karen Kelly, Jeffrey Warren Allen, Barbara J. Gitlitz, Philip C. Mack, David R. Gandara> ;Clinical Lung Cancer. 2016 Mar 1
ASCO 2015 update on gastrointestinal cancer: Checkpoint inhibition, multimodality strategies and secondary prevention.
Thomas J. Semrad> ;Surgical Oncology. 2015 Dec 1
7 citations
Integrating Chemotherapy into the Management of Oligometastatic Colorectal Cancer: Evidence-Based Approach Using Clinical Trial Findings
Thomas J. Semrad, Ana Milena Rodriguez Fahrni, I-Yeh Gong, Vijay P. Khatri> ;Annals of Surgical Oncology. 2015 Jun 23
57 citations
Phase I trial of arginine deprivation therapy with ADI-PEG 20 plus docetaxel in patients with advanced malignant solid tumors
Benjamin K. Tomlinson, Jim Thomson, John S. Bomalaski, Monica Diaz, Taiwo Akande, Nichole Mahaffey, Tianhong Li, Mrinal Dutia, Karen Kelly, I-Yeh Gong, Thomas J. Semra...> ;Clinical Cancer Research. 2015 Jun 1
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