ThomasDWuMDPhD

PubMed

• 34 citations
  IRE1α Disruption in Triple-Negative Breast Cancer Cooperates with Antiangiogenic Therapy by Reversing ER Stress Adaptation and Remodeling the Tumor Microenvironment.
  Jonathan M. Harnoss, Adrien Le Thomas, Mike Reichelt, Ofer Guttman, Thomas D. Wu, Scot A. Marsters, Anna Shemorry, David A. Lawrence, David Kan, Ehud Segal, Mark Merch...> ;Cancer Research. 2020 Jun 1
• 340 citations
  Peripheral T cell expansion predicts tumour infiltration and clinical response
  Thomas D. Wu, Shravan Madireddi, Patrícia de Almeida, Romain Banchereau, Ying-Jiun J. Chen, Avantika S. Chitre, Eugene Y. Chiang, Hina Iftikhar, William E. O'Gorman, A...> ;Nature. 2020 Feb 26
• 32 citations
  CD226 regulates natural killer cell antitumor responses via phosphorylation-mediated inactivation of transcription factor FOXO1.
  Xiangnan Du, Patrícia de Almeida, Nicholas A. Manieri, Denise E. de Almeida Nagata, Thomas D. Wu, Kristin Harden Bowles, Vidhyalakshmi Arumugam, Jill Schartner, Rafael...> ;Proceedings of the National Academy of Sciences of the United States of America. 2018 Dec 11
• 195 citations
  Membrane-Proximal Epitope Facilitates Efficient T Cell Synapse Formation by Anti-FcRH5/CD3 and Is a Requirement for Myeloma Cell Killing
  Ji Li, Nicola J. Stagg, Jennifer Johnston, Michael J. Harris, Sam A. Menzies, Danielle DiCara, Vanessa Clark, Maria Hristopoulos, Ryan Cook, Dionysos Slaga, Rin Nakamu...> ;Cancer Cell. 2017 Mar 13
• 64 citations
  Two Escape Mechanisms of Influenza A Virus to a Broadly Neutralizing Stalk-Binding Antibody
  Ning Chai, Lee R. Swem, Mike Reichelt, Haiyin Chen-Harris, Elizabeth Luis, Summer Park, Ashley E. Fouts, Patrick J. Lupardus, Thomas D. Wu, Olga Li, Jacqueline McBride...> ;Plos Pathogens. 2016 Jun 28
• 73 citations
  Prediction and Quantification of Splice Events from RNA-Seq Data
  Leonard D. Goldstein, Yi Cao, Gregoire Pau, Michael S. Lawrence, Thomas D. Wu, Somasekar Seshagiri, Robert Gentleman> ;Plos One. 2016 May 24
• 1 citations
  Bitpacking techniques for indexing genomes: II. Enhanced suffix arrays
  Thomas D. Wu> ;Algorithms for Molecular Biology. 2016 Apr 23
• Bitpacking techniques for indexing genomes: I. Hash tables
  Thomas D. Wu> ;Algorithms for Molecular Biology. 2016 Apr 18
• 584 citations
  Comprehensive genomic analysis of malignant pleural mesothelioma identifies recurrent mutations, gene fusions and splicing alterations
  Raphael Bueno, Eric Stawiski, Leonard D. Goldstein, Steffen Durinck, Assunta De Rienzo, Zora Modrusan, Florian Gnad, Thong T. Nguyen, Bijay S. Jaiswal, Lucian R. Chiri...> ;Nature Genetics. 2016 Apr 1
• 240 citations
  GMAP and GSNAP for Genomic Sequence Alignment: Enhancements to Speed, Accuracy, and Functionality.
  Thomas D. Wu, Jens Reeder, Michael S. Lawrence, Gabe Becker, Matthew J. Brauer> ;Methods in Molecular Biology. 2016 Jan 1
• 446 citations
  A comprehensive transcriptional portrait of human cancer cell lines
  Christiaan Klijn, Steffen Durinck, Eric Stawiski, Peter M. Haverty, Zhaoshi Jiang, Hanbin Liu, Jeremiah D. Degenhardt, Oleg Mayba, Florian Gnad, Jinfeng Liu, Gregoire ...> ;Nature Biotechnology. 2015 Mar 1
• 260 citations
  Spectrum of diverse genomic alterations define non-clear cell renal carcinoma subtypes.
  Steffen Durinck, Eric Stawiski, Andrea Pavia-Jimenez, Zora Modrusan, Payal Kapur, Bijay S. Jaiswal, Na Zhang, Vanina Toffessi-Tcheuyap, Thong T. Nguyen, Kanika Bajaj P...> ;Nature Genetics. 2015 Jan 1
• 88 citations
  Diverse modes of genomic alteration in hepatocellular carcinoma
  Suchit Jhunjhunwala, Zhaoshi Jiang, Eric Stawiski, Florian Gnad, Jinfeng Liu, Oleg Mayba, Pan Du, Jingyu Diao, Stephanie Johnson, Kwong-Fai Wong, Zhibo Gao, Yingrui Li...> ;Genome Biology. 2014 Aug 26
• 71 citations
  Integrated exome and transcriptome sequencing reveals ZAK isoform usage in gastric cancer
  Jinfeng Liu, Mark McCleland, Eric Stawiski, Florian Gnad, Oleg Mayba, Peter M. Haverty, Steffen Durinck, Ying-Jiun Chen, Christiaan Klijn, Suchit Jhunjhunwala, Michael...> ;Nature Communications. 2014 May 8
• Phenotypic characterization of the foldase homologue PrsA in Streptococcus mutans.
  Guo, L.,Wu, T.,Hu, W.,He, X.,Sharma, S.,Webster, P.,Gimzewski, J. K.,Zhou, X.,Lux, R.,Shi, W.> ;Mol Oral Microbiol. 2013 Apr
• 154 citations
  Genome and transcriptome sequencing of lung cancers reveal diverse mutational and splicing events
  Jinfeng Liu, William Lee, Zhaoshi Jiang, Zhongqiang Chen, Suchit Jhunjhunwala, Peter M. Haverty, Florian Gnad, Yinghui Guan, Houston Gilbert, Jeremy Stinson, Christiaa...> ;Genome Research. 2012 Dec 1
• 106 citations
  Disruption of PH–kinase domain interactions leads to oncogenic activation of AKT in human cancers
  Chaitali Parikh, Vasantharajan Janakiraman, Wen-I Wu, Catherine K. Foo, Noelyn M. Kljavin, Subhra Chaudhuri, Eric Stawiski, Brian Lee, Jie Lin, Hong Li, Maria N. Loren...> ;Proceedings of the National Academy of Sciences of the United States of America. 2012 Nov 20
• 751 citations
  Comprehensive genomic analysis identifies SOX2 as a frequently amplified gene in small-cell lung cancer
  Charles M. Rudin, Steffen Durinck, Eric Stawiski, John T. Poirier, Zora Modrusan, David S. Shames, Emily Bergbower, Yinghui Guan, James Shin, Joseph Guillory, Celina S...> ;Nature Genetics. 2012 Oct 1
• 733 citations
  Recurrent R-spondin fusions in colon cancer
  Somasekar Seshagiri, Eric Stawiski, Steffen Durinck, Zora Modrusan, Elaine E. Storm, Caitlin B. Conboy, Subhra Chaudhuri, Yinghui Guan, Vasantharajan Janakiraman, Bija...> ;Nature. 2012 Aug 30
• 217 citations
  The effects of hepatitis B virus integration into the genomes of hepatocellular carcinoma patients
  Zhaoshi Jiang, Suchit Jhunjhunwala, Jinfeng Liu, Peter M. Haverty, Michael I. Kennemer, Yinghui Guan, William Lee, Paolo Carnevali, Jeremy Stinson, Stephanie Johnson, ...> ;Genome Research. 2012 Jan 20
• 29 citations
  Influence of 17β-estradiol on gene expression of Paracoccidioides during mycelia-to-yeast transition.
  Jata Shankar, Thomas D. Wu, Karl V. Clemons, Jomar P. Monteiro, Laurence F. Mirels, David A. Stevens> ;Plos One. 2011 Dec 14
• 46 citations
  Proteolytic Activation of Pro-Macrophage-Stimulating Protein by Hepsin
  Rajkumar Ganesan, Ganesh Kolumam, S. Jack Lin, Ming-Hong Xie, Lydia Santell, Thomas D. Wu, Robert A. Lazarus, Amitabha Chaudhuri, Daniel Kirchhofer> ;Molecular Cancer Research. 2011 Sep 1
• Functional expression of P2X4 receptor in capillary endothelial cells of the cochlear spiral ligament and its role in regulating the capillary diameter.
  Wu, T.,Dai, M.,Shi, X. R.,Jiang, Z. G.,Nuttall, A. L.> ;Am. J. Physiol. Heart Circ. Physiol.. 2011 Apr 05
• 38 citations
  TMEFF2 is a PDGF-AA binding protein with methylation-associated gene silencing in multiple cancer types including glioma
  Kui Lin, James R. Taylor, Thomas D. Wu, Johnny Gutierrez, J. Michael Elliott, Jean-Michel Vernes, Hartmut Koeppen, Heidi S. Phillips, Frederic J. de Sauvage, Y. Gloria...> ;Plos One. 2011 Apr 29
• Effect of capsaicin on potassium conductance and electromotility of the guinea pig outer hair cell.
  Wu, T.,Song, L.,Shi, X.,Jiang, Z.,Santos-Sacchi, J.,Nuttall, A. L.> ;Hear. Res.. 2010 Nov 04
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