TimothyAllenFieldsMD

PubMed

• Notch3 deletion regulates HIV-1 gene expression and systemic inflammation to ameliorate chronic kidney disease.
  Mackenzie Thornton, Nicole Sommer, Mercedes McGonigle, Anil Kumar Ram, Sireesha Yerrathota, Henrietta Ehirim, Aakriti Chaturvedi, Johnny Dinh Phan, Praveen V Chakravar...> ;Biorxiv. 2023 Sep 13
• 1 citations
  Polycystin-1 Interacting Protein-1 (CU062) Interacts with the Ectodomain of Polycystin-1 (PC1).
  Wendy A Lea, Thomas Winklhofer, Lesya Zelenchuk, Madhulika Sharma, Jessica Rossol-Allison, Timothy A Fields, Gail Reif, James P Calvet, Jason L Bakeberg, Darren P Wall...> ;Cells. 2023 Aug 29
• Corrigendum to "Ttc21b deficiency attenuates autosomal dominant polycystic kidney disease in a kidney tubular- and maturation-dependent manner." Kidney Int. 2022;102:5...
  Wei Wang, Luciane M Silva, Henry H Wang, Matthew A Kavanaugh, Tana S Pottorf, Bailey A Allard, Damon T Jacobs, Ruochen Dong, Joseph T Cornelius, Aakriti Chaturvedi, Ka...> ;Kidney International. 2023 Jun 1
• Corrigendum to "Ttc21b deficiency attenuates autosomal dominant polycystic kidney disease in a kidney tubular- and maturation-dependent manner." Kidney Int. 2022;102:5...
  Wei Wang, Luciane M Silva, Henry H Wang, Matthew A Kavanaugh, Tana S Pottorf, Bailey A Allard, Damon T Jacobs, Rouchen Dong, Joseph T Cornelius, Aakriti Chaturvedi, Ka...> ;Kidney International. 2023 Feb 1
• 4 citations
  Myofibroblast depletion reduces kidney cyst growth and fibrosis in autosomal dominant polycystic kidney disease.
  Nidhi Dwivedi, Abeda Jamadar, Sijo Mathew, Timothy A Fields, Reena Rao> ;Kidney International. 2023 Jan 1
• 1 citations
  Expression of active B-Raf proto-oncogene in kidney collecting ducts induces cyst formation in normal mice and accelerates cyst growth in mice with polycystic kidney d...
  Stephen C Parnell, Archana Raman, Yan Zhang, Emily A Daniel, Yuqiao Dai, Aditi Khanna, Gail A Reif, Jay L Vivian, Timothy A Fields, Darren P Wallace> ;Kidney International. 2022 Nov 1
• 6 citations
  Ttc21b deficiency attenuates autosomal dominant polycystic kidney disease in a kidney tubular- and maturation-dependent manner.
  Wei Wang, Luciane M Silva, Henry H Wang, Matthew A Kavanaugh, Tana S Pottorf, Bailey A Allard, Damon T Jacobs, Rouchen Dong, Joseph T Cornelius, Aakriti Chaturvedi, Ka...> ;Kidney International. 2022 Sep 1
• 1 citations
  DOT1L Methyltransferase Regulates Calcium Influx in Erythroid Progenitor Cells in Response to Erythropoietin.
  Yi Feng, Shaon Borosha, Anamika Ratri, Eun Bee Lee, Huizhen Wang, Timothy A Fields, William H Kinsey, Jay L Vivian, M A Karim Rumi, Patrick E Fields> ;International Journal of Molecular Sciences. 2022 May 5
• 5 citations
  DOT1L Mediated Gene Repression in Extensively Self-Renewing Erythroblasts.
  Shaon Borosha, Anamika Ratri, Subhra Ghosh, Carrie A Malcom, V Praveen Chakravarthi, Jay L Vivian, Timothy A Fields, M A Karim Rumi, Patrick E Fields> ;Frontiers in Genetics. 2022 Jan 1
• 17 citations
  The tyrosine-kinase inhibitor Nintedanib ameliorates autosomal-dominant polycystic kidney disease.
  Abeda Jamadar, Sreenath M. Suma, Sijo Mathew, Timothy A. Fields, Darren P. Wallace, James P. Calvet, Reena Rao> ;Cell Death & Disease. 2021 Oct 14
• Posttransplant proteinuria due to Apolipoprotein E2 deposition in a kidney allograft.
  Madhuri Ramakrishnan, Timothy A. Fields, Da Zhang, Itunu Owoyemi, Aditi Gupta, Jeffrey A. Klein, Nicholas S. Herrera, Mallika Gupta, Diane M. Cibrik> ;American Journal of Transplantation. 2021 Aug 16
• 7 citations
  Primitive Erythropoiesis in the Mouse is Independent of DOT1L Methyltransferase Activity.
  Carrie A Malcom, Anamika Ratri, Joanna Piasecka-Srader, Shaon Borosha, V Praveen Chakravarthi, Nehemiah S Alvarez, Jay L Vivian, Timothy A Fields, M A Karim Rumi, Patr...> ;Frontiers in Cell and Developmental Biology. 2021 Jan 1
• 15 citations
  Glycogen synthase kinase-3β inhibits tubular regeneration in acute kidney injury by a FoxM1-dependent mechanism.
  Sonali Sinha, Nidhi Dwivedi, James R. Woodgett, Shixin Tao, Christianna Howard, Timothy A. Fields, Abeda Jamadar, Reena Rao> ;FASEB Journal. 2020 Oct 1
• 15 citations
  Epithelial Vasopressin Type-2 Receptors Regulate Myofibroblasts by a YAP-CCN2-Dependent Mechanism in Polycystic Kidney Disease.
  Nidhi Dwivedi, Shixin Tao, Abeda Jamadar, Sonali Sinha, Christianna Howard, Darren P. Wallace, Timothy A. Fields, Andrew Leask, James P. Calvet, Reena Rao> ;Journal of the American Society of Nephrology. 2020 Jun 17
• 5 citations
  BCL9/STAT3 regulation of transcriptional enhancer networks promote DCIS progression.
  Hanan S Elsarraj, Yan Hong, Darlene Limback, Ruonan Zhao, Jenna Berger, Stephanie C Bishop, Aria Sabbagh, Linzi Oppenheimer, Haleigh E Harper, Anna Tsimelzon, Shixia H...> ;NPJ Breast Cancer. 2020 Jan 1
• 46 citations
  Claudin-2 deficiency associates with hypercalciuria in mice and human kidney stone disease.
  Joshua N. Curry, Matthew Saurette, Masomeh Askari, Lei Pei, Michael B. Filla, Megan R Beggs, Peter S. N. Rowe, Timothy A. Fields, Andre J. Sommer, Chizu Tanikawa, Yoic...> ;The Journal of Clinical Investigation. 2020 Apr 1
• 12 citations
  Dietary phosphate restriction attenuates polycystic kidney disease in mice
  Faith Omede, Shiqin Zhang, Cassandra Johnson, Emily Daniel, Yan Zhang, Timothy A. Fields, Joseph Boulanger, Shiguang Liu, Ishfaq Ahmed, Shahid Umar, Darren P. Wallace,...> ;American Journal of Physiology. Renal Physiology. 2020 Jan 1
• 25 citations
  Inhibition of Endothelial PHD2 Suppresses Post-Ischemic Kidney Inflammation through Hypoxia-Inducible Factor-1.
  Ganeshkumar Rajendran, Michael Schonfeld, Ratnakar Tiwari, Shengping Huang, Rafael Torosyan, Timothy A. Fields, Jihwan Park, Katalin Susztak, Pinelopi P. Kapitsinou> ;Journal of the American Society of Nephrology. 2020 Jan 29
• 10 citations
  Notch4 activation aggravates NF-κB-mediated inflammation in HIV-1-associated nephropathy
  Rajni V. Puri, Sireesha Yerrathota, Trisha Home, Jessica Y. Idowu, V. Praveen Chakravarthi, Christopher J. Ward, Pravin C. Singhal, Gregory B. Vanden Heuvel, Timothy A...> ;Disease Models & Mechanisms. 2019 Dec 17
• 16 citations
  MCP-1 promotes detrimental cardiac physiology, pulmonary edema, and death in the cpk model of polycystic kidney disease.
  Sally M. Salah, James D. Meisenheimer, Reena Rao, Jacqueline D. Peda, Darren P. Wallace, Dawson Foster, Xiaogang Li, Xiaoyan Li, Xia Zhou, Julian Vallejo, Michael J. W...> ;American Journal of Physiology. Renal Physiology. 2019 Aug 1
• 26 citations
  Inhibition of Hedgehog signaling suppresses proliferation and microcyst formation of human Autosomal Dominant Polycystic Kidney Disease cells.
  Luciane M. Silva, Damon T. Jacobs, Bailey A. Allard, Timothy A. Fields, Madhulika Sharma, Darren P. Wallace, Pamela V. Tran> ;Scientific Reports. 2018 Mar 21
• 17 citations
  Trophoblast Glycoprotein (TPGB/5T4) in Human Placenta: Expression, Regulation, and Presence in Extracellular Microvesicles and Exosomes
  S.M. Alam, Susmita Jasti, Sarika Kshirsagar, Dionne Tannetta, R Dragovic, Christopher W.G. Redman, Ian L. Sargent, Herbert C. Hodes, Traci L. Nauser, T. Fortes, A. M. ...> ;Reproductive Sciences. 2018 Feb 1
• 4 citations
  Previable Preeclampsia Diagnosed by Renal Biopsy in Setting of Novel Diagnosis of C4 Glomerulopathy
  Jessica Parrott, Timothy A. Fields, Marc Parrish> ;Case Reports in Obstetrics and Gynecology. 2017 Jul 4
• 17 citations
  Autocrine IL-10 activation of the STAT3 pathway is required for pathological macrophage differentiation in polycystic kidney disease
  Jacqueline D. Peda, Sally M. Salah, Darren P. Wallace, Patrick E. Fields, Connor J. Grantham, Timothy A. Fields, Katherine I. Swenson-Fields> ;Disease Models & Mechanisms. 2016 Sep 1
• 60 citations
  Paracellular epithelial sodium transport maximizes energy efficiency in the kidney
  Lei Pei, Glenn Solis, Mien T. X. Nguyen, Nikhil Kamat, Lynn Magenheimer, Min Zhuo, Jiahua Li, Joshua N. Curry, Alicia A. McDonough, Timothy A. Fields, William J. Welch...> ;The Journal of Clinical Investigation. 2016 Jul 1
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