TimothyPatrickKegelmanMDPhD

PubMed

• Acute hospitalizations after proton therapy versus intensity-modulated radiotherapy for locally advanced non-small cell lung cancer in the durvalumab era.
  Iocolano, M., Yegya-Raman, N., Friedes, C., Wang, X., Kegelman, T., Lee, S., Duan, L., Li, B., Levin, W., Cengel, K., Konski, A., Langer, C., Cohen, R., Sun, L., Aggar...> ;Cancer. 2024 Jan 31
• 3 citations
  Cardiac radiation dose is associated with inferior survival but not cardiac events in patients with locally advanced non-small cell lung cancer in the era of immune ch...
  Nikhil Yegya-Raman, Sang Ho Lee, Cole Friedes, Xingmei Wang, Michelle Iocolano, Timothy P Kegelman, Lian Duan, Bolin Li, Eva Berlin, Kristine N Kim, Abigail Doucette, ...> ;Radiotherapy and Oncology. 2024 Jan 1
• Cardiovascular Substructure Dose and Cardiac Events following Proton- and Photon-Based Chemoradiotherapy for Non-Small Cell Lung Cancer.
  Jyotsna Natarajan, Nikhil Yegya-Raman, Timothy P Kegelman, Michael J Kallan, Leonid Roshkovan, Sharyn Katz, Bonnie Ky, Michael Fradley, Ying Xiao, Sang Ho Lee, Zheng Z...> ;Advances in Radiation Oncology. 2023 Apr 5
• 1 citations
  Death without progression as an endpoint to describe cardiac radiation effects in locally advanced non-small cell lung cancer.
  Nikhil Yegya-Raman, Timothy P Kegelman, Sang Ho Lee, Michael J Kallan, Kristine N Kim, Jyotsna Natarajan, Matthew P Deek, Wei Zou, Shannon E O'Reilly, Zheng Zhang, Wil...> ;Clinical and Translational Radiation Oncology. 2023 Mar 1
• Increased posterior cingulate cortex blood flow in cancer-related fatigue.
  David Raizen, Rupal Bhavsar, Brendan T Keenan, Patrick Z Liu, Timothy P Kegelman, Hann-Hsiang Chao, Neha Vapiwala, Hengyi Rao> ;Frontiers in Neurology. 2023 Jan 1
• 1 citations
  Toxicities and Deaths From Intercurrent Disease Following Contemporary Postoperative Radiotherapy in Resected Non-Small-Cell Lung Cancer.
  Kristine N Kim, Jonathan Heintz, Nikhil Yegya-Raman, Roger Cohen, Timothy Kegelman, Keith Cengel, Melina Marmarelis, Lova Sun, Corey Langer, Charu Aggarwal, Aditi Sing...> ;Clinical Lung Cancer. 2023 Mar 1
• 4 citations
  Factors Associated With Fatigue in Patients with Breast Cancer Undergoing External Beam Radiation Therapy
  Michael J. LaRiviere, Hann-Hsiang Chao, Abigail Doucette, Timothy Kegelman, Neil K. Taunk, Gary M. Freedman, Neha Vapiwala> ;Practical Radiation Oncology. 2020 Nov 1
• 15 citations
  Suppression of prostate cancer pathogenesis using an MDA-9/Syntenin (SDCBP) PDZ1 small molecule inhibitor
  Swadesh K. Das, Timothy P. Kegelman, Anjan K. Pradhan, Xue Ning Shen, Praveen Bhoopathi, Sarmistha Talukdar, Santanu Maji, Devanand Sarkar, Luni Emdad, Paul B. Fisher> ;Molecular Cancer Therapeutics. 2019 Nov 1
• 22 citations
  Astrocyte Elevated Gene-1 Regulates β-Catenin Signaling to Maintain Glioma Stem-like Stemness and Self-Renewal.
  Bin Hu, Luni Emdad, Timothy P. Kegelman, Xue-Ning Shen, Swadesh K. Das, Devanand Sarkar, Paul B. Fisher> ;Molecular Cancer Research. 2017 Feb 1
• 69 citations
  Inhibition of radiation-induced glioblastoma invasion by genetic and pharmacological targeting of MDA-9/Syntenin
  Timothy P. Kegelman, Bainan Wu, Swadesh K. Das, Sarmistha Talukdar, Jason M. Beckta, Bin Hu, Luni Emdad, Kristoffer Valerie, Devanand Sarkar, Frank B. Furnari, Webster...> ;Proceedings of the National Academy of Sciences of the United States of America. 2017 Jan 10
• 26 citations
  AEG-1/MTDH/LYRIC: A Promiscuous Protein Partner Critical in Cancer, Obesity, and CNS Diseases.
  Luni Emdad, Swadesh K. Das, Bin Hu, Timothy P. Kegelman, Dong-Chul Kang, Seok-Geun Lee, Devanand Sarkar, Paul B. Fisher> ;Advances in Cancer Research. 2016 Jan 1
• 7 citations
  The Quest for an Effective Treatment for an Intractable Cancer: Established and Novel Therapies for Pancreatic Adenocarcinoma.
  Bridget A. Quinn, Nathaniel Lee, Timothy P. Kegelman, Praveen Bhoopathi, Luni Emdad, Swadesh K. Das, Maurizio Pellecchia, Devanand Sarkar, Paul B. Fisher> ;Advances in Cancer Research. 2015 Jan 1
• 55 citations
  Astrocyte elevated gene-1 interacts with Akt isoform 2 to control glioma growth, survival, and pathogenesis.
  Bin Hu, Luni Emdad, Manny D. Bacolod, Timothy P. Kegelman, Xue-Ning Shen, Mohammad A. Alzubi, Swadesh K. Das, Devanand Sarkar, Paul B. Fisher> ;Cancer Research. 2014 Dec 15
• 45 citations
  Targeting tumor invasion: the roles of MDA-9/Syntenin.
  Timothy P. Kegelman, Swadesh K. Das, Luni Emdad, Bin Hu, Mitchell E. Menezes, Praveen Bhoopathi, Xiang-Yang Wang, Maurizio Pellecchia, Devanand Sarkar, Paul B. Fisher> ;Expert Opinion on Therapeutic Targets. 2015 Jan 1
• 49 citations
  MDA-9/syntenin is a key regulator of glioma pathogenesis
  Timothy P. Kegelman, Swadesh K. Das, Bin Hu, Manny D. Bacolod, Christine E. Fuller, Mitchell E. Menezes, Luni Emdad, Santanu Dasgupta, Albert S. Baldwin, Jeffrey N. Br...> ;Neuro-Oncology. 2014 Jan 1
• 18 citations
  In vivo modeling of malignant glioma: the road to effective therapy.
  Timothy P. Kegelman, Bin Hu, Luni Emdad, Swadesh K. Das, Devanand Sarkar, Paul B. Fisher> ;Advances in Cancer Research. 2014 Jan 1
• 73 citations
  MDA-9/syntenin and IGFBP-2 promote angiogenesis in human melanoma.
  Swadesh K. Das, Sujit K. Bhutia, Belal Azab, Timothy P. Kegelman, Leyla Peachy, Prasanna K. Santhekadur, Santanu Dasgupta, Rupesh Dash, Paul Dent, Steven Grant, Luni E...> ;Cancer Research. 2013 Jan 15
• 12 citations
  Selected Approaches for Rational Drug Design and High Throughput Screening to Identify Anti-Cancer Molecules
  Michael Hedvat, Luni Emdad, Swadesh K. Das, Keetae Kim, Santanu Dasgupta, Shibu Thomas, Bin Hu, Shan Zhu, Rupesh Dash, Bridget A. Quinn, Regina A. Oyesanya, Timothy P....> ;Anti-Cancer Agents in Medicinal Chemistry. 2012 Oct 31
• 29 citations
  mda-7/IL-24 differentially regulates soluble and nuclear clusterin in prostate cancer
  Sujit K. Bhutia, Swadesh K. Das, Timothy P. Kegelman, Belal Azab, Rupesh Dash, Zhao-zhong Su, Xiang-Yang Wang, Federica Rizzi, Saverio Bettuzzi, Seok-Geun Lee, Paul De...> ;Journal of Cellular Physiology. 2012 May 1
• 57 citations
  MDA-9/syntenin: a positive gatekeeper of melanoma metastasis.
  Swadesh K. Das, Sujit K. Bhutia, Timothy P. Kegelman, Leyla Peachy, Regina A. Oyesanya, Santanu Dasgupta, Upneet K. Sokhi, Belal Azab, Rupesh Dash, Bridget A. Quinn, K...> ;Frontiers in Bioscience. 2012 Jan 1
• 85 citations
  Oncogene AEG-1 Promotes Glioma-Induced Neurodegeneration by Increasing Glutamate Excitotoxicity
  Seok-Geun Lee, Keetae Kim, Timothy P. Kegelman, Rupesh Dash, Swadesh K. Das, Jung Kyoung Choi, Luni Emdad, Eric L. Howlett, Hyun Yong Jeon, Zhao Zhong Su, Byoung Kwon ...> ;Cancer Research. 2011 Oct 15
• 285 citations
  Role of Excitatory Amino Acid Transporter‐2 (EAAT2) and glutamate in neurodegeneration: Opportunities for developing novel therapeutics
  Keetae Kim, Seok-Geun Lee, Timothy P. Kegelman, Zhao-zhong Su, Swadesh K. Das, Rupesh Dash, Santanu Dasgupta, Paola M. Barral, Michael Hedvat, Paul Diaz, John C. Reed,...> ;Journal of Cellular Physiology. 2011 Oct 1
• 13 citations
  Astrocyte elevated gene-1 activates AMPK in response to cellular metabolic stress and promotes protective autophagy.
  Sujit K. Bhutia, Timothy P. Kegelman, Swadesh K. Das, Belal Azab, Zhao-zhong Su, Seok-Geun Lee, Devanand Sarkar, Paul B. Fisher> ;Autophagy. 2011 May 1
• 92 citations
  Astrocyte elevated gene-1 induces protective autophagy
  Sujit K. Bhutia, Timothy P. Kegelman, Swadesh K. Das, Belal Azab, Zhao-zhong Su, Seok-Geun Lee, Devanand Sarkar, Paul B. Fisher> ;Proceedings of the National Academy of Sciences of the United States of America. 2010 Dec 21
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