TimothyJPanellaMD

Hematology • Knoxville, TN

University Cancer Specialists

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Office
1934 Alcoa Hwy
Ste 474
Knoxville, TN 37920
Phone+1 865-305-8780
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Education & Training

Duke University HospitalFellowship, Hematology and Medical Oncology, 1986 - 1989
UMass Chan Medical SchoolResidency, Internal Medicine, 1983 - 1986
University of Tennessee Health Science Center College of MedicineClass of 1983

Certifications & Licensure

TN State Medical License 1991 - 2025
NC State Medical License 1986 - 1992
American Board of Internal Medicine Internal Medicine
American Board of Internal Medicine Medical Oncology

Awards, Honors, & Recognition

Regional Top Doctor Castle Connolly, 2014

Clinical Trials

Radiation Therapy With or Without Trastuzumab in Treating Women With Ductal Carcinoma In Situ Who Have Undergone Lumpectomy Start of enrollment: 2008 Nov 10
Active, not recruiting
Phase 3
A Phase III Randomized Trial of Metformin vs Placebo in Early Stage Breast Cancer Start of enrollment: 2010 Aug 13
Completed
Phase 3
Tamoxifen Citrate, Letrozole, Anastrozole, or Exemestane With or Without Chemotherapy in Treating Patients With Invasive RxPONDER Breast Cancer Start of enrollment: 2011 Jan 15
Active, not recruiting
Phase 3
S1207 Hormone Therapy With or Without Everolimus in Treating Patients With Breast Cancer Start of enrollment: 2013 Sep 12
Active, not recruiting
Phase 3
A Phase II Study of Everolimus in Combination With Exemestane Versus Everolimus Alone Versus Capecitabine in Advance Breast Cancer. Start of enrollment: 2013 Feb 26
Completed
Phase 2
Study Comparing Combination of LGX818 Plus MEK162 Versus Vemurafenib and LGX818 Monotherapy in BRAF Mutant Melanoma Start of enrollment: 2013 Dec 13
Active, not recruiting
Phase 3
Study of Efficacy and Safety of LEE011 in Men and Postmenopausal Women With Advanced Breast Cancer. Start of enrollment: 2015 Jun 09
Completed
Phase 3
Doxorubicin Hydrochloride and Cyclophosphamide Followed by Paclitaxel With or Without Carboplatin in Treating Patients With Triple-Negative Breast Cancer Start of enrollment: 2015 Jul 26
Recruiting
Phase 3
Study of PDS0101 and Pembrolizumab Combination I/O in Subjects With HPV16 + Recurrent and/or Metastatic HNSCC Start of enrollment: 2021 Mar 29
Active, not recruiting
Phase 2
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Publications & Presentations

PubMed

Fusion Identified in a Patient with Medullary Thyroid Carcinoma.
Omar Alsharif, Timothy Panella, Laurentia Nodit, Mimi I Hu> ;Thyroid. 2023 Jun 1
9 citations
STARBOARD: encorafenib + binimetinib + pembrolizumab for first-line metastatic/unresectableV600-mutant melanoma.
Dirk Schadendorf, Reinhard Dummer, Caroline Robert, Antoni Ribas, Ryan J Sullivan, Timothy Panella, Meredith McKean, Edgardo S Santos, Kimberli Brill, Anna Polli, Ales...> ;Future Oncology. 2022 Jun 1
4 citations
Breast Cancer in Elderly Caucasian Women-An Institution-Based Study of Correlation between Breast Cancer Prognostic Markers, TNM Stage, and Overall Survival.
Amila Orucevic, Matthew Curzon, Christina Curzon, Robert E. Heidel, James M. McLoughlin, Timothy Panella, John L. Bell> ;Cancers. 2015 Jul 31
75 citations
Administration of ipilimumab to a liver transplant recipient with unresectable metastatic melanoma.
Harsha Ranganath, Timothy J Panella> ;Journal of Immunotherapy. 2015 May 26
22 citations
Is the TNM Staging System for Breast Cancer Still Relevant in the Era of Biomarkers and Emerging Personalized Medicine for Breast Cancer – An Institution's 10‐year Exp...
Amila Orucevic, Jason Chen, James M. McLoughlin, Robert E. Heidel, Timothy Panella, John L. Bell> ;The Breast Journal. 2015 Mar 1
61 citations
Prognostic value of breast cancer subtypes, Ki-67 proliferation index, age, and pathologic tumor characteristics on breast cancer survival in Caucasian women.
N. Lynn Ferguson, John L. Bell, Robert E. Heidel, Solomon Lee, Stuart VanMeter, Lisa D. Duncan, Barbara Munsey, Timothy Panella, Amila Orucevic> ;The Breast Journal. 2013 Jan 1
24 citations
A randomized phase II study of paclitaxel and bevacizumab with and without gemcitabine as first-line treatment for metastatic breast cancer.
Adam Brufsky, Karen Hoelzer, Thaddeus Beck, Robert C. Whorf, Mark Keaton, Padma Nadella, Elisa Krill-Jackson, Joan Kroener, Edward Middleman, Michael Frontiera, Devcha...> ;Clinical Breast Cancer. 2011 Aug 1
4 citations
Metastasis of squamous cell carcinoma of the bladder to the heart: Case report and review of the literature
Wesley M. White, W. Bedford Waters, Timothy Panella, Frederick A. Klein> ;Urology. 2006 Oct 1
19 citations
Sarcoma of mandible
Eric R. Carlson, Timothy Panella, Jon D. Holmes> ;Journal of Oral and Maxillofacial Surgery. 2004 Jan 1
4 citations
Phase II trial of pyrazoloacridine in advanced non-small cell carcinoma of the lung--a Kansas Cancer Institute and Thompson Cancer Survival Center Study.
Michael Bastasch, Timothy J. Panella, Shari L Kretzschmer, Debbie Graham, Matt Mayo, Stephen K. Williamson> ;Investigational New Drugs. 2002 Aug 1
9 citations
Phase II study of Didemnin B in central nervous system tumors: a Southwest Oncology Group study
Sarah A. Taylor, Dorothy Giroux, Kurt A. Jaeckle, Timothy J. Panella, Shaker R. Dakhil, S. Clifford Schold> ;Investigational New Drugs. 1998 Dec 1
1 citations
Relative sedimentation of hematopoietic progenitors in human cord blood, peripheral blood, and bone marrow as determined by counterflow centrifugal elutriation
Nazareth Gengozian, Roberta J. Hill, Michael R. Caudle, Timothy J. Panella> ;Transplantation. 1998 Apr 15
23 citations
Evaluation of multimodality treatment of locoregional esophageal carcinoma by Southwest Oncology Group 9060.
Elizabeth A. Poplin, Joth Jacobson, Arnold Herskovic, Timothy J. Panella, Manuel Valdivieso, Laura F. Hutchins, John S. Macdonald> ;Cancer. 1996 Nov 1
23 citations
RELATIONSHIP BETWEEN RESPONSE RATE AND MEDIAN SURVIVAL IN PATIENTS WITH ADVANCED NONSMALL CELL LUNG-CANCER - COMPARISON OF ONCONASE(R) WITH OTHER ANTICANCER AGENTS
Sm Mikulski, Hoo G. Chun, Abraham Mittelman, Timothy Panella, C. Puccio, Kuslima Shogen, John J. Costanzi> ;International Journal of Oncology. 1995 Apr 1
16 citations
Phase II trial and cost analysis of fazarabine in advanced non-small cell carcinoma of the lung: a Southwest Oncology Group study.
Stephen K. Williamson, John Crowley, Robert B. Livingston, Timothy J. Panella, John Wendall Goodwin> ;Investigational New Drugs. 1995 Jan 1
22 citations
A phase I/II trial of twice daily irradiation and concurrent chemotherapy for locally advanced squamous cell carcinoma of the head and neck.
David M. Brizel, Kenneth A. Leopold, Samuel R. Fisher, Timothy J. Panella, Robert L. Fine, C.L. Bedrosian, Patrick D. Kenan, Andrew T. Huang, Teresa Womack, Toni Bjurs...> ;International Journal of Radiation Oncology, Biology, Physics. 1994 Jan 1
175 citations
High-Dose Oral Tamoxifen, a Potential Multidrug-Resistance-Reversal Agent: Phase I Trial in Combination With Vinblastine
Donald L. Trump, David C. Smith, Peter G. Ellis, Miriam P. Rogers, S. Clifford Schold, Eric P. Winer, Timothy J. Panella, V. Craig Jordan, Robert L. Fine> ;Journal of the National Cancer Institute. 1992 Dec 2
60 citations
Differential molecular mechanism of the estrogen action that regulates lactoferrin gene in human and mouse.
Christina T. Teng, Youhua Liu, Nengyu Yang, David K. Walmer, Timothy J. Panella> ;Molecular Endocrinology. 1992 Nov 1
19 citations
Paraneoplastic hepatopathy associated with soft tissue sarcoma
Ala I. Sharara, Timothy J. Panella, J. Gregory Fitz> ;Gastroenterology. 1992 Jul 1
22 citations
Modulation of O6-Alkylguanine-DNA Alkyltransferase-mediated Carmustine Resistance Using Streptozotocin: A Phase I Trial
Timothy J. Panella, David C. Smith, S. C. Schold, M P Rogers, Eric P. Winer, Robert L. Fine, Jeffrey Crawford, J E Herndon nd, Donald L. Trump> ;Cancer Research. 1992 May 1
50 citations
Polymorphism and Altered Methylation of the Lactoferrin Gene in Normal Leukocytes, Leukemic Cells, and Breast Cancer
Timothy J. Panella, Youhua Liu, Andrew T. Huang, Christina T. Teng> ;Cancer Research. 1991 Jun 1
3 citations
Absence of phosphatidylinositol (PI)-linked proteins in a very early human multipotential haematopoietic marrow cell.
Andrew T. Huang, Timothy J. Panella, Nelda G. Mold, Wendell F. Rosse> ;British Journal of Haematology. 1991 Feb 1
4 citations
Effect of Thimerosal in Leukemia, in Leukemic Cell Lines, and on Normal Hematopoiesis
Timothy J. Panella, Andrew T. Huang> ;Cancer Research. 1990 Jul 15
25 citations
Platelets acquire a secretion defect after high-dose chemotherapy.
Timothy J. Panella, William L. Peters, James G. White, Yusuf A. Hannun, Charles S. Greenberg> ;Cancer. 1990 Apr 15
124 citations
Phase II Trial of a Single Weekly Intravenous Dose of Ranpirnase in Patients With Unresectable Malignant Mesothelioma
Stanislaw M. Mikulski, John J. Costanzi, Nicholas J. Vogelzang, Spence McCachren, Robert N. Taub, Hoo Chun, Abraham Mittelman, Timothy Panella, Carmelo Puccio, Robert ...> ;Journal of Clinical Oncology. 2002 Jan 1
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Professional Memberships

American College of Physicians - ACP
Member
American Society of Clinical Oncology - ASCO
Member

Hospital Affiliations

University of Tennessee Medical CenterKnoxville, Tennessee

TimothyJPanellaMD

Dr. Panella is on Doximity

Education & Training

Certifications & Licensure

Awards, Honors, & Recognition

Clinical Trials

Publications & Presentations

Professional Memberships

Hospital Affiliations

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