Timothy J Pluard MD

Breast Cancer

Koontz Endowed Chair in Breast Disease, University of Missouri, Kansas City School of Medicine. Director Saint Luke's Cancer Institute

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4401 Wornall RdKansas City, MO 64111
Phone+1 816-932-3800
Fax+1 816-932-3888

Education & Training

Mass General Brigham/Brigham and Women's Hospital/Massachusetts General Hospital/Dana-Farber Cancer InstituteFellowship, Hematology and Medical Oncology, 1991 - 1993
University of Texas Southwestern Medical CenterResidency, Internal Medicine, 1987 - 1991
Washington University in St. Louis School of MedicineClass of 1987

Certifications & Licensure

MO State Medical License 1993 - 2026
KS State Medical License 2014 - 2024
FL State Medical License 2020 - 2022
TX State Medical License 1988 - 1992
American Board of Internal Medicine Medical Oncology

Clinical Trials

Goserelin and Letrozole or Anastrozole in Premenopausal Patients With Stage II-III Estrogen Receptor-Positive Breast Cancer Start of enrollment: 2011 Sep 01
Terminated
Phase 2
A Study of the Experimental Drug BKM120 With Paclitaxel in Patients With HER2 Negative, Locally Advanced or Metastatic Breast Cancer, With or Without PI3K Activation Start of enrollment: 2012 Aug 01
Completed
Phase 2, Phase 3
Neratinib +/- Fulvestrant in Metastatic HER2 Non-amplified But HER2 Mutant Breast Cancer Start of enrollment: 2012 Dec 11
Completed
Phase 2
Post Operative Adjuvant Therapy De-intensification Trial for Human Papillomavirus-related, p16+ Oropharynx Cancer Start of enrollment: 2013 Jan 10
Terminated
Phase 3
Levocetirizine + Capecitabine + Bevacizumab for Patients With Refractory Colorectal Cancer Start of enrollment: 2013 Apr 01
Completed
Phase 2
VEGFR/PDGFR Dual Kinase Inhibitor X-82 and Everolimus for Treating Patients With Pancreatic Neuroendocrine Tumors Start of enrollment: 2013 May 03
Terminated
Phase 1, Phase 2
Axillary Ultrasound With or Without Sentinel Lymph Node Biopsy in Detecting the Spread of Breast Cancer in Patients Receiving Breast Conservation Therapy Start of enrollment: 2013 Apr 04
Terminated
Not Applicable
Study of Efficacy and Safety of LEE011 in Postmenopausal Women With Advanced Breast Cancer Start of enrollment: 2013 Dec 17
COMPLETED
PHASE3
Open-label, Phase II Study of Stomatitis Prevention With a Steroid-based Mouthwash in Post-menopausal Women With Estrogen-receptor-positive (ER+), Human Epidermal Growth Factor Receptor 2 (HER2)- Metastatic or Locally Advanced Breast Cancer Start of enrollment: 2014 May 01
Completed
Phase 2
A Study of Abemaciclib (LY2835219) Combined With Fulvestrant in Women With Hormone Receptor Positive HER2 Negative Breast Cancer Start of enrollment: 2014 Jul 22
ACTIVE_NOT_RECRUITING
PHASE3
Trilaciclib (G1T28), a CDK 4/6 Inhibitor, in Combination With Gemcitabine and Carboplatin in Metastatic Triple Negative Breast Cancer (mTNBC) Start of enrollment: 2017 Feb 02
Terminated
Phase 2
Oral Paclitaxel Efficacy Safety and PK in Recurrent and Metastatic Breast Cancer Start of enrollment: 2018 Jul 06
Completed
Phase 2
A Study of Tucatinib or Placebo With Trastuzumab and Pertuzumab for Metastatic HER2+ Breast Cancer Start of enrollment: 2022 Mar 07
ACTIVE_NOT_RECRUITING
PHASE3
Roles: Contact, Principal Investigator
Evaluation of Lasofoxifene Combined With Abemaciclib Compared With Fulvestrant Combined With Abemaciclib in Locally Advanced or Metastatic ER+/HER2- Breast Cancer With an ESR1 Mutation Start of enrollment: 2023 Oct 31
RECRUITING
PHASE3
Roles: Contact
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Publications & Presentations

PubMed

Relationship of Prior Anticancer Treatments with Palbociclib Clinical Outcomes in Patients with HR/HER2Advanced Breast Cancer in Real-World Settings.
Gabrielle B Rocque, Joanne L Blum, Yan Ji, Timothy Pluard, John Migas
Targeted Oncology. 2025-07-01
Palazestrant, a novel oral Complete Estrogen Receptor Antagonist (CERAN) and Selective Estrogen Receptor Degrader (SERD), in patients with ER+/HER2- advanced or metast...
Erika P Hamilton, Manish R Patel, Virginia F Borges, Jane L Meisel, Meena Okera
Breast Cancer Research. 2025-07-01
Zanidatamab plus palbociclib and fulvestrant in previously treated patients with hormone receptor-positive, HER2-positive metastatic breast cancer: primary results fro...
Santiago Escrivá-de-Romani, Juan M Cejalvo, Emilio Alba, Jennifer Friedmann, Álvaro Rodríguez-Lescure
The Lancet. Oncology. 2025-06-01

Lectures

The Utility of Hereditary Thrombophilia Testing Among Hospitalized Patients: A Single Center Experience
2018 ASH Annual Meeting - San Diego, CA - 12/1/2018
Highlights of the 2011 San Antonio Breast Cancer Symposium
Washington University School of Medicine, Saint Louis, Missouri - 2/11/2012

Press Mentions

'Have Hope': Study Shows Immunotherapy Continues to Change Future of Cancer TreatmentApril 30th, 2025
The Power of Metastatic Breast Cancer Retreats with Lillie Shockney and Janie Metsker: Part 1October 28th, 2022
Saint Luke's Cancer Institute & Patient Discovery Launches Innovative Digital Advocate for Advance Care PlanningJune 10th, 2021
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