TimothyJTaylorDO

PubMed

• 11 citations
  Water quality characteristics of discharge from reforested loose-dumped mine spoil in eastern Kentucky.
  Carmen T. Agouridis, Patrick Angel, Timothy J. Taylor, Christopher D. Barton, Richard C. Warner, Xia Yu, Constance L. Wood> ;Journal of Environmental Quality. 2012 Mar 1
• 48 citations
  Optimization of the physicochemical and pharmacokinetic attributes in a 6-azauracil series of P2X7 receptor antagonists leading to the discovery of the clinical candid...
  Allen J. Duplantier, Mark A. Dombroski, Chakrapani Subramanyam, Aimee M. Beaulieu, Shang Poa Chang, Christopher A. Gabel, Crystal K. Jordan, Amit S. Kalgutkar, Kenneth...> ;Bioorganic & Medicinal Chemistry Letters. 2011 Jun 15
• 15 citations
  Preclinical pharmacokinetics and metabolism of 6-(4-(2,5-difluorophenyl)oxazol-5-yl)-3-isopropyl-[1,2,4]-triazolo[4,3-a]pyridine, a novel and selective p38α inhibitor:...
  Amit S. Kalgutkar, Heather L. Hatch, Frederick Kosea, Hang T. Nguyen, Edna F. Choo, Kim F. McClure, Timothy J. Taylor, Kirk R. Henne, Alexander V. Kuperman, Mark A. Do...> ;Biopharmaceutics & Drug Disposition. 2006 Nov 1
• 16 citations
  Structure-activity relationships of triazolopyridine oxazole p38 inhibitors: identification of candidates for clinical development.
  Kim F. McClure, Michael A. Letavic, Amit S. Kalgutkar, Christopher A. Gabel, Laurent P. Audoly, John T. Barberia, John F. Braganza, Demetrius Carter, Thomas J. Carty, ...> ;Bioorganic & Medicinal Chemistry Letters. 2006 Aug 15
• 4 citations
  Absolute oral bioavailability of traxoprodil in cytochrome P450 2D6 extensive and poor metabolisers.
  Timothy J. Taylor, Kelly Diringer, Tanya Russell, Karthik Venkatakrishnan, Keith D. Wilner, Penelope Crownover, Lisa J. Benincosa, Megan A. Gibbs> ;Clinical Pharmacokinetics. 2006 Jan 1
• 13 citations
  Influence of lipophilicity on the interactions of N-alkyl-4-phenyl-1,2,3,6-tetrahydropyridines and their positively charged N-alkyl-4-phenylpyridinium metabolites with...
  Amit S. Kalgutkar, Sue Zhou, Odette A. Fahmi, Timothy J. Taylor> ;Drug Metabolism and Disposition. 2003 May 1
• 42 citations
  Assessment of the contributions of CYP3A4 and CYP3A5 in the metabolism of the antipsychotic agent haloperidol to its potentially neurotoxic pyridinium metabolite and e...
  Amit S. Kalgutkar, Timothy J. Taylor, Karthik Venkatakrishnan, Emre M. Isin> ;Drug Metabolism and Disposition. 2003 Mar 1
• 59 citations
  On the Diversity of Oxidative Bioactivation Reactions on Nitrogen- Containing Xenobiotics
  Amit S. Kalgutkar, Deepak Dalvie, John P. O'Donnell, Timothy J. Taylor, Diana C. Sahakian> ;Current Drug Metabolism. 2002 Jul 31
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