TomasRodriguezMD

PubMed

• 16 citations
  CRISPR/Cas9-mediated excision of ALS/FTD-causing hexanucleotide repeat expansion in C9ORF72 rescues major disease mechanisms in vivo and in vitro.
  Katharina E Meijboom, Abbas Abdallah, Nicholas P Fordham, Hiroko Nagase, Tomás Rodriguez, Carolyn Kraus, Tania F Gendron, Gopinath Krishnan, Rustam Esanov, Nadja S And...> ;Nature Communications. 2022 Oct 21
• 4 citations
  Expression Indicates Lymph Node Metastasis and Presence of Cancer-Associated Fibroblasts in Papillary Thyroid Cancer.
  Sina Dadafarin, Tomás C Rodríguez, Michelle A Carnazza, Raj K Tiwari, Augustine Moscatello, Jan Geliebter> ;Cells. 2022 Oct 10
• 1 citations
  Multiomics characterization of mouse hepatoblastoma identifies yes-associated protein 1 target genes.
  Tomás C Rodríguez, Suet-Yan Kwan, Jordan L Smith, Sina Dadafarin, Chern-Horng Wu, Erik J Sontheimer, Wen Xue> ;Hepatology. 2023 Jul 1
• 12 citations
  Intratracheally administered LNA gapmer antisense oligonucleotides induce robust gene silencing in mouse lung fibroblasts.
  Minwook Shin, Io Long Chan, Yuming Cao, Alisha M Gruntman, Jonathan Lee, Jacquelyn Sousa, Tomás C Rodríguez, Dimas Echeverria, Gitali Devi, Alexandre J Debacker, Micha...> ;Nucleic Acids Research. 2022 Aug 26
• 8 citations
  Adenine Base Editingwith a Single Adeno-Associated Virus Vector.
  Han Zhang, Nathan Bamidele, Pengpeng Liu, Ogooluwa Ojelabi, Xin D Gao, Tomás Rodriguez, Haoyang Cheng, Karen Kelly, Jonathan K Watts, Jun Xie, Guangping Gao, Scot A Wo...> ;GEN Biotechnology. 2022 Jun 1
• 65 citations
  A split prime editor with untethered reverse transcriptase and circular RNA template.
  Bin Liu, Xiaolong Dong, Haoyang Cheng, Chunwei Zheng, Zexiang Chen, Tomás C Rodríguez, Shun-Qing Liang, Wen Xue, Erik J Sontheimer> ;Nature Biotechnology. 2022 Sep 1
• 1 citations
  Dorsal Column Stimulation and Cannabinoids in the Treatment of Chronic Nociceptive and Neuropathic Pain: a Review of the Clinical and Pre-clinical Data.
  Charles A Odonkor, Tariq AlFarra, Peju Adekoya, Vwaire Orhurhu, Tomás Rodríguez, Emily Sottosanti, Alan D Kaye> ;Current Pain and Headache Reports. 2022 Feb 1
• 16 citations
  Pathogen infection and cholesterol deficiency activate thep38 immune pathway through a TIR-1/SARM1 phase transition.
  Nicholas D Peterson, Janneke D Icso, J Elizabeth Salisbury, Tomás Rodríguez, Paul R Thompson, Read Pukkila-Worley> ;Elife. 2022 Jan 31
• 17 citations
  CRISPR-enhanced human adipocyte browning as cell therapy for metabolic disease.
  Emmanouela Tsagkaraki, Sarah M. Nicoloro, Tiffany DeSouza, Javier Solivan-Rivera, Anand Desai, Lawrence M. Lifshitz, Yuefei Shen, Mark J. S. Kelly, Adilson L. Guilherm...> ;Nature Communications. 2021 Nov 26
• 40 citations
  Self-inactivating, all-in-one AAV vectors for precision Cas9 genome editing via homology-directed repair in vivo.
  Raed Ibraheim, Phillip W. L. Tai, Aamir Mir, Nida Javeed, Jiaming Wang, Tomás Rodríguez, Suk Namkung, Samantha J. Nelson, Eraj Khokhar, Esther Mintzer, Stacy Maitland,...> ;Nature Communications. 2021 Nov 1
• 11 citations
  Androgen Activity Is Associated With PD-L1 Downregulation in Thyroid Cancer.
  Timmy O'Connell, Sina Dadafarin, Melanie Jones, Tomás Rodríguez, Anvita Gupta, Edward Shin, Augustine Moscatello, Codrin Iacob, Humayun Islam, Raj K. Tiwari, Jan Gelie...> ;Frontiers in Cell and Developmental Biology. 2021 Aug 6
• 7 citations
  Genome-wide detection and analysis of CRISPR-Cas off-targets
  Tomás Rodríguez, Sina Dadafarin, Henry Pratt, Pengpeng Liu, Nadia Amrani, Lihua Julie Zhu> ;Progress in Molecular Biology and Translational Science. 2021 Jan 1
• 10 citations
  YAP1 Withdrawal in Hepatoblastoma Drives Therapeutic Differentiation of Tumor Cells to Functional Hepatocyte-Like Cells
  Jordan L. Smith, Tomás Rodríguez, Haiwei Mou, Suet-Yan Kwan, Henry Pratt, Xiao-Ou Zhang, Yueying Cao, Shun-Qing Liang, Deniz M. Ozata, Tianxiong Yu, Qiangzong Yin, Max...> ;Hepatology. 2021 Mar 1
• 70 citations
  An engineered ScCas9 with broad PAM range and high specificity and activity
  Pranam Chatterjee, Noah Jakimo, Jooyoung Lee, Nadia Amrani, Tomás Rodríguez, Sabrina R. T. Koseki, Emma Tysinger, Rui Qing, Shilei Hao, Erik J. Sontheimer, Joseph M. J...> ;Nature Biotechnology. 2020 May 11
• Adapting dCas9-APEX2 for subnuclear proteomic profiling.
  Gao XD, Rodríguez TC, Sontheimer EJ> ;Methods in enzymology. 2018-12-10
• 74 citations
  C-BERST: defining subnuclear proteomic landscapes at genomic elements with dCas9–APEX2
  Xin D. Gao, Li-Chun Tu, Aamir Mir, Tomás Rodríguez, Yue-He Ding, John D. Leszyk, Job Dekker, Scott A. Shaffer, Lihua Julie Zhu, Scot A. Wolfe, Erik J. Sontheimer> ;Nature Methods. 2018 May 7
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