TrentEdwardTippleMDFAAP

PubMed

• Effects of DNA methylase inhibitors in a murine model of severe BPD.
  Kathryn M Heyob, Zahra Khuhro, Aiman Q Khan, Dorian Brown, Trent E Tipple, Lynette K Rogers> ;Respiratory Physiology & Neurobiology. 2023 Jul 1
• 3 citations
  Microbial-induced Redox Imbalance in the Neonatal Lung Is Ameliorated by Live Biotherapeutics.
  Amelia E Freeman, Kent A Willis, Luhua Qiao, Ahmed S Abdelgawad, Brian Halloran, Gabriel Rezonzew, Zoha Nizami, Nancy Wenger, Amit Gaggar, Namasivayam Ambalavanan, Tre...> ;American Journal of Respiratory Cell and Molecular Biology. 2023 Mar 1
• 1 citations
  Neonatal Selenium Deficiency Decreases Selenoproteins in the Lung and Impairs Pulmonary Alveolar Development.
  Laura G Sherlock, William C McCarthy, Maya R Grayck, Mack Solar, Andres Hernandez, Lijun Zheng, Cassidy Delaney, Trent E Tipple, Clyde J Wright, Eva S Nozik> ;Antioxidants. 2022 Dec 7
• 3 citations
  Transcriptomic-Metabolomic Profiling in Mouse Lung Tissues Reveals Sex- and Strain-Based Differences.
  Jolyn Fernandes, Katelyn Dunigan-Russell, Hua Zhong, Vivian Lin, Mary Silverberg, Stephanie B Moore, ViLinh Tran, Dean P Jones, Peter F Vitiello, Lynette K Rogers, Tre...> ;Metabolites. 2022 Sep 30
• 5 citations
  Maternal-Fetal Immunologic Response to SARS-CoV-2 Infection in a Symptomatic Vulnerable Population: A Prospective Cohort.
  Ramon Larcade, Lise DeShea, Gillian A Lang, Mauricio T Caballero, Adrian Ferretti, William H Beasley, Trent E Tipple, Nestor Vain, Luis Prudent, Mark L Lang, Fernando ...> ;The Journal of Infectious Diseases. 2022 Mar 2
• 50 citations
  Advances in Neonatal Acute Kidney Injury
  Michelle C. Starr, Jennifer R. Charlton, Ronnie Guillet, Kimberly J. Reidy, Trent E. Tipple, Jennifer G. Jetton, Alison L. Kent, Carolyn Abitbol, Namasivayam Ambalavan...> ;Pediatrics. 2021 Nov 1
• 9 citations
  Auranofin-Mediated NRF2 Induction Attenuates Interleukin 1 Beta Expression in Alveolar Macrophages
  Stephanie B. Wall, Rui Li, Brittany Butler, Ashley R. Burg, Hubert M. Tse, Jennifer L. Larson-Casey, A. Brent Carter, Clyde J. Wright, Lynette K. Rogers, Trent E. Tipple> ;Antioxidants. 2021 Apr 21
• 9 citations
  MicroRNA 219-5p inhibits alveolarization by reducing platelet derived growth factor receptor-alpha
  Amelia Freeman, Luhua Qiao, Nelida Olave, Gabriel Rezonzew, Samuel J. Gentle, Brian Halloran, Gloria S. Pryhuber, Amit Gaggar, Trent E. Tipple, Namasivayam Ambalavanan...> ;Respiratory Research. 2021 Feb 17
• 4 citations
  Neonatal Selenoenzyme Expression Is Variably Susceptible to Duration of Maternal Selenium Deficiency.
  Laura G Sherlock, Durganili Balasubramaniyan, Lijun Zheng, Miguel Zarate, Thomas Sizemore, Cassidy Delaney, Trent E. Tipple, Clyde J. Wright, Eva Nozik-Grayck> ;Antioxidants. 2021 Feb 14
• 14 citations
  Glutathione reductase deficiency alters lung development and hyperoxic responses in neonatal mice.
  Mary E. Robbins, Hye Youn Cho, Jason M. Hansen, Joseph R. Luchsinger, Morgan L. Locy, Markus Velten, Steven R. Kleeberger, Lynette K. Rogers, Trent E. Tipple> ;Redox Biology. 2021 Jan 1
• 14 citations
  Hepatic-Specific Decrease in the Expression of Selenoenzymes and Factors Essential for Selenium Processing After Endotoxemia.
  Laura G Sherlock, Kara Sjostrom, Lei Sian, Cassidy Delaney, Trent E. Tipple, Nancy F. Krebs, Eva Nozik-Grayck, Clyde J. Wright> ;Frontiers in Immunology. 2020 Nov 5
• 7 citations
  Selenium-independent antioxidant and anti-inflammatory effects of thioredoxin reductase inhibition in alveolar macrophages.
  Sara Staples, Stephanie B. Wall, Rui Li, Trent E. Tipple> ;Life Sciences. 2020 Oct 15
• 10 citations
  Quantitation of spin probe-detectable oxidants in cells using electron paramagnetic resonance spectroscopy: To probe or to trap?
  John P. Gotham, Rui Li, Trent E. Tipple, Jack R. Lancaster, Taiming Liu, Qian Li> ;Free Radical Biology & Medicine. 2020 Jul 1
• 5 citations
  Club Cell Heme Oxygenase-1 Deletion: Effects in Hyperoxia-Exposed Adult Mice.
  Katelyn Dunigan-Russell, Mary Silverberg, Vivian Y Lin, Rui Li, Stephanie B. Wall, Qian Li, Teodora Nicola, John Gotham, David R. Crowe, Peter F. Vitiello, Anupam Agar...> ;Oxidative Medicine and Cellular Longevity. 2020 Jun 9
• 4 citations
  Aurothioglucose enhances proangiogenic pathway activation in lungs from room air and hyperoxia-exposed newborn mice.
  Katelyn Dunigan-Russell, Vivian Y. Lin, Mary Silverberg, Stephanie B. Wall, Rui Li, John P. Gotham, Teodora Nicola, Anusha Sridharan, John Snowball, Cassidy Delaney, Q...> ;American Journal of Physiology. Lung Cellular and Molecular Physiology. 2020 Apr 15
• 26 citations
  Preterm birth and neonatal acute kidney injury: implications on adolescent and adult outcomes.
  Matthew W. Harer, Jennifer R. Charlton, Trent E. Tipple, Kimberly J. Reidy> ;Journal of Perinatology. 2020 Apr 10
• 1 citations
  Neonatal comorbidities and gasotransmitters.
  Samuel J. Gentle, Trent E. Tipple, Rakesh P. Patel> ;Nitric Oxide. 2020 Apr 1
• 10 citations
  Thiol-Redox Regulation in Lung Development and Vascular Remodeling
  Gaston Ofman, Trent E. Tipple> ;Antioxidants & Redox Signaling. 2019 Sep 11
• 38 citations
  L-NAME releases nitric oxide and potentiates subsequent nitroglycerin-mediated vasodilation.
  Taiming Liu, Meijuan Zhang, George T. Mukosera, Dan Borchardt, Qian Li, Trent E. Tipple, Abu Shufian Ishtiaq Ahmed, Gordon G. Power, Arlin B. Blood> ;Redox Biology. 2019 Jun 4
• 12 citations
  Oxygen Toxicity in the Neonate: Thinking Beyond the Balance.
  Trent E. Tipple, Namasivayam Ambalavanan> ;Clinics in Perinatology. 2019 Sep 1
• 4 citations
  The discovery BPD (D-BPD) program: study protocol of a prospective translational multicenter collaborative study to investigate determinants of chronic lung disease in...
  Gaston Ofman, Mauricio T. Caballero, Damian Alvarez Paggi, Jacqui Marzec, Florencia Nowogrodzki, Hye-Youn Cho, Mariana Sorgetti, Guillermo Colantonio, Alejandra Bianch...> ;BMC Pediatrics. 2019 Jul 6
• 9 citations
  Cyclic O3 exposure synergizes with aging leading to memory impairment in male APOE ε3, but not APOE ε4, targeted replacement mice
  Chunsun Jiang, Luke T. Stewart, Hui-Chien Kuo, William McGilberry, Stephanie B. Wall, Bill Liang, Thomas van Groen, Shannon M. Bailey, Young-il Kim, Trent E. Tipple, D...> ;Neurobiology of Aging. 2019 Sep 1
• 18 citations
  Antioxidants & bronchopulmonary dysplasia: Beating the system or beating a dead horse?
  Gaston Ofman, Trent E. Tipple> ;Free Radical Biology & Medicine. 2019 Oct 1
• 14 citations
  Thioredoxin Reductase-1 Inhibition Augments Endogenous Glutathione-Dependent Antioxidant Responses in Experimental Bronchopulmonary Dysplasia.
  Stephanie B. Wall, Rachael Wood, Katelyn Dunigan, Qian Li, Rui Li, Lynette K. Rogers, Trent E. Tipple> ;Oxidative Medicine and Cellular Longevity. 2019 Jan 21
• 10 citations
  Alterations in VASP phosphorylation and profilin1 and cofilin1 expression in hyperoxic lung injury and BPD.
  Mehboob Ali, Kathryn M. Heyob, Trent E. Tipple, Gloria S. Pryhuber, Lynette K. Rogers> ;Respiratory Research. 2018 Nov 21
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Journal Articles

• DHA Suppresses Chronic Apoptosis in the Lung Caused by Perinatal Inflammation  
  Ali M, Heyob KM, Velten M, Rogers, LK, American Journal of Physiology: Lung Cellular and Molecular Physiology, 1/1/2015
• microRNA-17~92 Cluster Expression is Significantly Attenuated in Bronchopulmonary Dysplasia  
  Rogers LK, Robbins M, Dukhlallah D, Yang Z, Lee LJ, Mikhail M, Nuovo G, Pryhuber GS, McGwin G, Marsh CB, AnnalsATS, 1/1/2015
• Maternal Dietary Docosahexaenoic Acid (DHA) Supplementation Prevents Fetal Growth Restriction and Pulmonary Injury in a Newborn Murine Model of Perinatal Inflammation  
  Velten M, Britt RD, Heyob KM, Rogers LK, Journal of Nutrition, 1/1/2014
• The Thioredoxin Reductase-1 Inhibitor Aurothioglucose Attenuates Lung Injury and Improves Survival in a Murine Model of Acute Respiratory Distress Syndrome  
  Britt RD, Velten M, Locy ML, Rogers LK, Antioxidants and Redox Signaling, 1/1/2014
• Arginase II is a Target of miR-17-5p and Regulates miR-17-5p Expression in Human Pulmonary Artery Smooth Muscle Cells  
  Jin Y, Jin Y, Chen B, Nelin LD, American Journal of Physiology: Lung Cellular and Molecular Physiology, 1/1/2014
• The Thioredoxin System in Neonatal Lung Disease  
  Tipple TE, Antioxidants and Redox Signaling, 1/1/2014
• Cyclooxygenase-2 in Newborn Hyperoxic Lung Injury  
  Britt RD, Velten M, Nelin LD, Rogers LK, Free Radical Biology and Medicine, 1/1/2013
• Thioredoxin-1 Mediates Hypoxia-Induced Pulmonary Artery Smooth Muscle Cell Proliferation  
  Chen B, Nelin VE, Locy ML, Jin Y, American Journal of Physiology: Lung Cellular and Molecular Physiology, 1/1/2013
• Neonatal Hyperoxic Exposure Persistently Alters Lung Secretoglobin and Annexin Expression  
  Raffay TM, Locy ML, Hill CL, Rogers LK, Welty SE, Biomedical Research International, 1/1/2013
• Lipopolysaccharide-induced Cyclooxygenase-2 Expression in Mouse Transformed Clara Cells  
  Britt RD, Locy ML, Nelin LD, Rogers LK, Cellular Physiology and Biochemistry, 1/1/2012
• Plasma Lipid Metabolites are Associated with Gestational Age but Not Bronchopulmonary Dysplasia  
  Rogers LK, Young CM, Pennell ML, Leonhart KL, Welty SE, Acta Paediatrica, 1/1/2012
• Perinatal Inflammation and Neonatal Oxygen Contributes to an Emphysematous and Fibrotic Lung Phenotype in Adult Mice  
  Velten M, Britt RD, Heyob KM, Welty SE, Rogers LK, American Journal of Physiology: Regulatory Integrative and Comparative Physiology, 1/1/2012
• Thioredoxin Reductase Inhibition Elicits Nrf2-mediated Responses in Clara Cells: Implications for Oxidant-induced Lung Injury  
  Locy ML, Rogers LK, Prigge JR, Schmidt EE, Arnér ESJ, Antioxidants and Redox Signaling, 1/1/2012
• Maternal DHA Supplementation Decreases Lung Inflammation in Hyperoxia-Exposed Newborn Mice  
  Rogers LK, Valentine CJ, Pennell M, Velten M, Britt RD, Dingess K, Zhao X, Welty SE, Journal of Nutrition, 1/1/2011
• Riboflavin Supplementation Does Not Attenuate Hyperoxic Lung Injury in Transgenic spc-mt hGR Mice  
  Heyob KM, Rogers LK, Welty SE, Experimental Lung Research, 1/1/2011
• Hyperoxia Exposure Alters Hepatic Lipid Metabolism in Newborn Mice  
  Rogers LK, Britt RD, Welty SE, Pediatric Research, 1/1/2010
• Thioredoxin Interacting Protein Inhibits Hypoxia-Inducible Factor Transcriptional Activity  
  Farrell MR, Rogers LK, Lu Y, Welty SE, Free Radical Biology and Medicine, 1/1/2010
• Differential Response in the Lungs of Newborn Mouse Pups Exposed to 85% or >95% Oxygen  
  Rogers LK, Nelin LD, and Welty SE, Pediatric Research, 1/1/2009
• Alterations of the Lung Thioredoxin System By Hyperoxia: Implications for Alveolarization  
  Welty SE, Nelin LD, Hansen JM, Rogers LK, American Journal of Respiratory Cell and Molecular Biology, 1/1/2009
• Thioredoxin Related Mechanisms in Hyperoxic Lung Injury in Mice  
  Welty SE, Rogers LK, Hansen TN, Choi YE, Kehrer JP, Smith CV, American Journal of Respiratory Cell and Molecular Biology, 1/1/2007
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Books/Book Chapters

• Reference Module in Biomedical Sciences 
  Chapter: Mechanisms: Free Radicals and Reactive Oxygen Species 
  Kehrer JP, Robertson JD, Smith CVEditors: Michael Caplan.Elsevier2014
• Methods in Molecular Biology – Developmental Toxicology 
  Chapter: Methods for the Determination of Plasma or Tissue Glutathione Levels 
  Page 315 - 324Tipple TE, Rogers LKEditors: Craig Harris and Jason Hansen.Humana Press, London2012
• General Principles, Toxicokinetics, and Mechanisms of Toxicity 
  Chapter: Mechanisms: Free Radicals and Reactive Oxygen Species 
  Page 277 - 307Kehrer JP, Robertson JD, Smith CVEditors: J.A. Bond.Elsevier2010

Abstracts/Posters

• Decreased Plasma miR-17~92 Cluster Expression in the First Week of Life Correlates with a Subsequent Diagnosis of Bronchopulmonary Dysplasia
  Yang Z, Lee LJ, McGwin G, Rogers LK, American Journal of Respiratory and Critical Care Medicine, 1/1/2015
• Haplotype-Insufficiency of miR-17~92 Cluster Alters Lung Development in Newborn Mice
  Robbins ME, Rogers LK, Piper MG, Pediatric Academic Societies, 1/1/2014
• Thioredoxin Reductase Inhibition Attenuates Hyperoxia-induced Lung Developmental Deficits in Newborn Mice
  Hill CL, Pierce DL, Velten M, Rogers LK, American Journal of Respiratory and Critical Care Medicine, 1/1/2014
• Pharmacological Inhibition of Thioredoxin Reductase-1 Attenuates Hyperoxic Lung Injury by Augmenting Glutathione Synthesis
  Rogers LK, Britt RD, Velten M, The Toxicologist, 1/1/2013
• Aurothioglucose Improves Survival in a Murine Model of Acute Respiratory Distress Syndrome
  Britt RD, Rogers LK, Pediatric Academic Societies, 1/1/2013
• miR-17~92 Cluster Expression Is Decreased in Lungs from Infants with Bronchopulmonary Dysplasia
  Robbins M, Rogers LK, Dakhlallah D, Piper MG, Pediatric Academic Societies, 1/1/2013
• Robbins ME, Rogers LK, Piper MG, Pediatric Academic Societies, 1/1/2013
• Maternal Dietary Docosahexaenoic acid (DHA) Supplementation Prevents Fetal Growth Restriction and Pulmonary Fibrosis Caused by Perinatal Inflammation
  Britt RD, Heyob KM, Rogers LK, FASEB Journal, 1/1/2013
• Aurothioglucose Enhances Glutathione Levels And Improves Survival In A Murine Model Of Acute Respiratory Distress Syndrome
  Britt RD, Locy ML, Velten M, Rogers LK, American Journal of Respiratory and Critical Care Medicine, 1/1/2013
• miR-17~92 Cluster Expression Is Decreased In Bronchopulmonary Dysplasia
  Robbins M, Dakhlallah D, Rogers LK, Piper MG, American Journal of Respiratory and Critical Care Medicine, 1/1/2013
• Aurothioglucose Improves Alveolarization in a Newborn Mouse Model of Bronchopulmonary Dysplasia
  Moyer S, Pierce D, Hill CL, Rogers LK, Free Radical Biology and Medicine, 1/1/2013
• Perinatal Inflammation and Decreases in miR29b-1 Expression are Associated with Structural and Functional Pulmonary Deficits in Adult Mice
  Velten M, Heyob KM, Welty SE, Rogers LK, FASEB Journal, 1/1/2012
• Thioredoxin-1 Mediates Hypoxia induced Pulmonary Artery Smooth Muscle Cell Proliferation
  Nelin V, Gin Y, Rogers LK, Nelin LD, FASEB Journal, 1/1/2012
• Neonatal Inflammation Contributes to Fibrotic Lung Disease in Adult Mice
  Rogers LK, Britt RD, Heyob KM, Velten M, The Toxicologist, 1/1/2012
• Maternal DHA Supplementation Improves Lung Growth and Function in Offspring Exposed to LPS and Hyperoxia
  Velten M, Heyob KM, Britt RD, Valentine CJ, Rogers LK, FASEB Journal, 1/1/2012
• Perinatal Inflammation Negatively Impacts Lung Structure and Function in Adult Mice
  Velten M, Britt RD, Heyob KM, Rogers LK, American Journal of Respiratory and Critical Care Medicine, 1/1/2012
• Oxidized Intracellular Glutathione Redox State in Neonatal Mice Persistently Alters Alveolar Epithelial Composition
  Robbins ME, Locy ML, Hill CL, Hansen JM, Rogers LK, Pediatric Academic Societies, 1/1/2012
• Pam2CSK, a TLR2 agonist, Increases Chemokine Expression in Mouse Transformed Clara Cells
  Britt RD, Locy ML, Rogers LK, American Journal of Respiratory and Critical Care Medicine, 1/1/2012
• Inhibition of Cox-2 Decreases Macrophage Infiltration in Newborn Hyperoxic Lung Injury
  Rogers LK, Velten M, Britt RD, Free Radical Biology and Medicine, 1/1/2012
• Aurothioglucose Enhances Lung Glutathione Levels and Improves Survival in a Murine Model of Acute Respiratory Distress Syndrome
  Britt RD, Locy ML, Rogers LK, Free Radical Biology and Medicine, 1/1/2012
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Lectures

• Targeting Thioredoxin Reductase to Prevent Oxygen-Induced Lung Injury 
  University of Alabama at Birmingham - 1/1/2015
• Decreased Plasma miR-17~92 Cluster Expression in the First Week of Life Correlates with a Subsequent Diagnosis of Bronchopulmonary Dysplasia 
  Denver, CO - 1/1/2015
• Thioredoxin Reductase: A Novel Therapeutic Target to Prevent Oxidant Lung Injury 
  Sanford Research Institute, Sioux Falls, SD - 1/1/2015
• Thioredoxin Reductase Inhibition to Prevent Lung Injury: Interplay With Cadmium and Selenium 
  Emory University, Atlanta, GA - 1/1/2015
• An Antioxidant Paradox: Inhibition of Thioredoxin Reductase to Prevent Pulmonary Disease 
  National Institute of Environmental Health Sciences, Research Triangle Park, NC, 2014; University of - 1/1/2014
• Physician + Scientist: The Good News is You Can Do Both 
  Butler University, Indianapolis, IN - 1/1/2014
• Thioredoxin Reductase Inhibition Attenuates Hyperoxia-induced Lung Developmental Deficits in Newborn Mice 
  San Diego, CA - 1/1/2014
• Reflections on a Blessed Existence 
  Columbus, OH - 1/1/2014
• Novel Strategies to Improve Outcomes in Infants With Bronchopulmonary Dysplasia 
  Nationwide Children’s Hospital - 1/1/2014
• Aurothioglucose Enhances Glutathione Levels and Improves Survival in a Murine Model of Acute Respiratory Distress Syndrome 
  Philadelphia, PA - 1/1/2013
• miR-17~92 Cluster is Decreased in Lungs from Infants With Bronchopulmonary Dysplasia 
  Washington, DC - 1/1/2013
• Aurothioglucose Improves Alveolarization in a Murine Model of Bronchopulmonary Dysplasia 
  San Antonio, TX - 1/1/2013
• An Antioxidant Paradox: Inhibition of Thioredoxin Reductase to Prevent Bronchopulmonary Dysplasia 
  Chicago, IL - 1/1/2013
• miR-17~92 Cluster Expression is Decreased in Bronchopulmonary Dysplasia 
  1/1/2013
• Serendipity: When the Fellowship Project You Tried to Forget Comes Full Circle 
  The Research Institute at Nationwide Children’s Hospital - 1/1/2013
• Respiratory Distress in the Newborn 
  1/1/2013
• Thioredoxin-1 Modulates Hypoxia-Induced Pulmonary Artery Smooth Muscle Cell Proliferation 
  Atlanta, GA - 1/1/2011
• Many Moments of Gratitude 
  Columbus, OH - 1/1/2011
• Respiratory Distress Syndrome 
  1/1/2010
• Thioredoxin Interacting Protein-Dependent Regulation of VEGF-Mediated Lung Development 
  1/1/2010
• The Jaundiced Newborn 
  1/1/2010
• Overexpression of Thioredoxin Interacting Protein Decreases Hypoxia Response Element Promoter Activity in Murine Alveolar Cells 
  San Francisco, CA - 1/1/2009
• Alterations of the Thioredoxin System by Hyperoxia: Implications for Alveolar Development 
  Houston, TX - 1/1/2008
• Pulmonary VEGF and Thioredoxin Interacting Protein Levels are Inversely Correlated in a Neonatal Mouse Model of BPD 
  Honolulu, HI - 1/1/2008
• Oxygen Toxicity: Basic Mechanisms and Biochemistry 
  1/1/2008
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