TristanKnightMDFRCPC(He/Him)

PubMed

• Chimeric Antigen Receptor T-Cell Therapy in the Outpatient Setting: An Expert Panel Opinion from the American Society for Transplantation and Cellular Therapy.
  Olalekan O Oluwole, Bhagirathbhai Dholaria, Tristan E Knight, Tania Jain, Frederick L Locke, Linda Ramsdell, Sarah Nikiforow, Hamza Hashmi, Kathy Mooney, Shakthi T Bha...> ;Transplantation and Cellular Therapy. 2024 Feb 1
• 30 citations
  Immune Effector Cell-Associated Hemophagocytic Lymphohistiocytosis-Like Syndrome.
  Ombrello, A. K., Ombrello, A. K., Melissa R Hines, Tristan E Knight, Kevin O McNerney, Mark B Leick, Tania Jain, Sairah Ahmed, Matthew J Frigault, Joshua A Hill, Micha...> ;Transplantation and Cellular Therapy. 2023 Jul 1
• Effect of Autograft CD34Dose on Outcome in Pediatric Patients Undergoing Autologous Hematopoietic Stem Cell Transplant for Central Nervous System Tumors.
  Tristan E Knight, Kwang Woo Ahn, Kyle M Hebert, Rasha Atshan, Donna A Wall, Kanhatai Chiengthong, Seth J Rotz, Ellen Fraint, Hemalatha G Rangarajan, Jeffery J Auletta,...> ;Transplantation and Cellular Therapy. 2023 Jun 1
• 10 citations
  "FLipping" the Story: FLT3-Mutated Acute Myeloid Leukemia and the Evolving Role of FLT3 Inhibitors.
  Tristan E Knight, Holly Edwards, Soheil Meshinchi, Jeffrey W Taub, Yubin Ge> ;Cancers. 2022 Jul 13
• 1 citations
  American Society for Transplantation and Cellular Therapy Guidelines for Fellowship Training in Hematopoietic Cell Transplantation and Immune Effector Cell Therapy.
  Tania Jain, Tristan Knight, Maritza C Alencar, Laurie Davis, Kamakshi Rao, Annie Im, Adriana K Malone> ;Transplantation and Cellular Therapy. 2022 Mar 1
• 2 citations
  When it comes to drug access, should children be considered small adults? Countering coverage denials of FLT3 inhibitors in children with FLT3-ITD AML
  Tristan Knight, Yubin Ge, Jeffrey W. Taub, Johann Hitzler, Joerg Krueger> ;Pediatric Blood & Cancer. 2021 Aug 6
• MAP4K1 expression is a novel resistance mechanism and independent prognostic marker in AML-but can be overcome via targeted inhibition
  Tristan Knight, Holly Edwards, Jeffrey W. Taub, Yubin Ge> ;Ebiomedicine. 2021 Jul 16
• Allogeneic hematopoietic stem cell transplantation in an adolescent with Prader-Willi syndrome - unique considerations
  Tristan Knight, Jane Lowry, Sarah Leppington, Donna A. Wall, Jennifer Seelisch> ;Pediatric Hematology and Oncology. 2021 Jun 15
• 22 citations
  The combination of CUDC-907 and gilteritinib shows promising in vitro and in vivo antileukemic activity against FLT3-ITD AML
  Xinan Qiao, Jun Ma, Tristan Knight, Yongwei Su, Holly Edwards, Lisa Polin, Jing Li, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Jian Wang, Hai Lin, Yue Wang, Li...> ;Blood Cancer Journal. 2021 Jun 7
• 3 citations
  Severe Acute Respiratory Syndrome Coronavirus 2 and Coronavirus Disease 2019: A Clinical Overview and Primer.
  Tristan Knight> ;Biopreservation and Biobanking. 2020 Jul 23
• 27 citations
  The HDAC and PI3K dual inhibitor CUDC-907 synergistically enhances the antileukemic activity of venetoclax in preclinical models of acute myeloid leukemia.
  Xinyu Li, Yongwei Su, Katie Hege, Gerard J. Madlambayan, Holly Edwards, Tristan Knight, Lisa Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Jay Yang, Regan ...> ;Haematologica. 2020 Mar 12
• 7 citations
  Successful Treatment of an Adolescent Male With Severe Refractory Evans Syndrome Using Bortezomib-based Therapy
  Tristan Knight, Yaddanapudi Ravindranath, Michael U. Callaghan> ;Journal of Pediatric Hematology/oncology. 2020 Mar 1
• 2 citations
  Clostridium difficile infection in a children's hospital with specific patterns among pediatric oncology and hematopoietic stem cell transplantation populations.
  Jessica L. Spruit, Tristan Knight, Colleen Sweeney, Hossein Salimnia, Süreyya Savaşan> ;Pediatric Hematology and Oncology. 2020 Jan 29
• 96 citations
  Inhibition of Bcl-2 Synergistically Enhances the Antileukemic Activity of Midostaurin and Gilteritinib in Preclinical Models of FLT3-mutated Acute Myeloid Leukemia
  Jun Ma, Shoujing Zhao, Xinan Qiao, Tristan Knight, Holly Edwards, Lisa Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Guan Wang, Lijing Zhao, Hai Lin, Yue W...> ;Clinical Cancer Research. 2019 Nov 15
• 47 citations
  Antileukemic activity and mechanism of action of the novel PI3K and histone deacetylase dual inhibitor CUDC-907 in acute myeloid leukemia
  Xinyu Li, Yongwei Su, Gerard J. Madlambayan, Holly Edwards, Lisa Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Jun Ma, Tristan Knight, Guan Wang, Yue Wang,...> ;Haematologica. 2019 Nov 1
• 2 citations
  Simultaneous cotargeting of ATR and RNA Polymerase I transcription demonstrates synergistic antileukemic effects on acute myeloid leukemia.
  Tingting Wang, Margaret Shatara, Fangbing Liu, Tristan Knight, Holly Edwards, Guan Wang, Hai Lin, Yue Wang, Jeffrey W Taub, Yubin Ge> ;Signal Transduction and Targeted Therapy. 2019 Nov 1
• 25 citations
  Current Management of Pleuropulmonary Blastoma: A Surgical Perspective.
  Samantha Knight, Tristan Knight, Amir A. Khan, Andrew J. Murphy> ;Children. 2019 Jul 25
• 13 citations
  Mild erythrocytosis as a presenting manifestation of PIEZO1 associated erythrocyte volume disorders
  Tristan Knight, Ahmar U. Zaidi, Shengnan Wu, Manisha Gadgeel, Steven Buck, Yaddanapudi Ravindranath> ;Pediatric Hematology and Oncology. 2019 Jul 12
• 3 citations
  Antibiotic Susceptibility of Bloodstream Isolates in a Pediatric Oncology Population: The Case for Ongoing Unit-specific Surveillance
  Tristan Knight, Darryl W. Glaser, Natascha Ching, Marian E. Melish> ;Journal of Pediatric Hematology/oncology. 2019 Jul 1
• 5 citations
  Venetoclax Synergistically Enhances the Anti-leukemic Activity of Vosaroxin Against Acute Myeloid Leukemia Cells Ex Vivo.
  Fangbing Liu, Tristan Knight, Yongwei Su, Holly Edwards, Guan Wang, Yue Wang, Jeffrey W. Taub, Hai Lin, Liwei Sun, Yubin Ge> ;Targeted Oncology. 2019 Jun 1
• 13 citations
  Evaluating Venetoclax and Its Potential in treatment-naïve Acute Myeloid Leukemia
  Tristan Knight, Holly Edwards, Jeffrey W. Taub, Yubin Ge> ;Cancer Management and Research. 2019 Apr 23
• 106 citations
  A delicate balance - The BCL-2 family and its role in apoptosis, oncogenesis, and cancer therapeutics.
  Tristan Knight, Daniel A. Luedtke, Holly Edwards, Jeffrey W. Taub, Yubin Ge> ;Biochemical Pharmacology. 2019 Apr 1
• 3 citations
  Different Clonal T-Large Granular Lymphocyte Proliferations in SCID.
  Süreyya Savaşan, Erin Wakeling, Tristan Knight, Steven Buck, Manisha Gadgeel> ;Journal of Clinical Immunology. 2019 Mar 27
• 8 citations
  Dramatic response to trametinib in a male child with neurofibromatosis type 1 and refractory astrocytoma
  Tristan Knight, Margaret Shatara, Lindsey Carvalho, Deniz Altinok, Janet Poulik, Zhihong Joanne Wang> ;Pediatric Blood & Cancer. 2019 Jan 1
• 24 citations
  The role of emicizumab, a bispecific factor IXa- and factor X-directed antibody, for the prevention of bleeding episodes in patients with hemophilia A:
  Tristan Knight, Michael U. Callaghan> ;Therapeutic Advances in Hematology. 2018 Oct 10
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Lectures

• The Combination of CUDC-907 and Gilteritinib Shows Promising Antileukemic Activity in Vitro and In Vivo in Preclinical Models of FLT3-ITD AML 
  61st Annual American Society of Hematology Meeting - Orlando, FL - 12/7/2019