TroyHGuthrieJr.MD

Oncology • Jacksonville, FL

Professor of Medicine, University Fla College of Medicine

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Office
7751 Baymeadows Rd E
3rd Floor
Jacksonville, FL 32256
Phone+1 904-493-5100

Fax+1 904-493-5130
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Education & Training

Medical College of GeorgiaFellowship, Hematology and Medical Oncology, 1977 - 1979
University of Texas Health Science Center San Antonio Joe and Teresa Lozano Long School of MedicineResidency, Internal Medicine, 1971 - 1974
Medical College of Georgia at Augusta UniversityClass of 1971

Certifications & Licensure

FL State Medical License 1994 - 2025
GA State Medical License 1972 - 2005
American Board of Internal Medicine Internal Medicine
American Board of Internal Medicine Medical Oncology

Awards, Honors, & Recognition

Regional Top Doctor Castle Connolly, 2014
CMS Meaningful Use Stage 1 Certification OncoEMR, Altos Solutions, Inc., 2013

Clinical Trials

Chemotherapy With or Without Bevacizumab in Treating Patients With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma Start of enrollment: 2008 Aug 08
Active, not recruiting
Phase 3
Radiation Therapy With or Without Trastuzumab in Treating Women With Ductal Carcinoma In Situ Who Have Undergone Lumpectomy Start of enrollment: 2008 Nov 10
Active, not recruiting
Phase 3
Lenalidomide With or Without Epoetin Alfa in Treating Patients With Myelodysplastic Syndrome and Anemia Start of enrollment: 2009 Jan 29
Active, not recruiting
Phase 3
Lenalidomide or Observation in Treating Patients With Asymptomatic High-Risk Smoldering Multiple Myeloma Start of enrollment: 2011 Jan 24
Active, not recruiting
Phase 3
Studying First Line Treatment of Chronic Myeloid Leukemia (CML) in a Real-world Setting Start of enrollment: 2010 Dec 02
Completed
Cisplatin and Etoposide With or Without Veliparib in Treating Patients With Extensive Stage Small Cell Lung Cancer Start of enrollment: 2012 Sep 28
Completed
Phase 1, Phase 2
Study to Evaluate Efficacy, Safety, Tolerability, and Pharmacodynamics of Entospletinib in Adults With Relapsed or Refractory Hematologic Malignancies Start of enrollment: 2013 Mar 14
Terminated
Phase 2
Study of Glembatumumab Vedotin (CDX-011) in Patients With Metastatic, gpNMB Over-Expressing, Triple Negative Breast Cancer Start of enrollment: 2013 Nov 01
Completed
Phase 2
Study of TH-302 or Placebo in Combination With Pemetrexed in Patients With Non-squamous Non-small Cell Lung Cancer Start of enrollment: 2014 Jun 01
Terminated
Phase 2
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Publications & Presentations

PubMed

6 citations
Isolated leptomeningeal progression from sinonasal carcinomas: Implications for staging workup and treatment.
Roi Dagan, Curtis Bryant, William M. Mendenhall, Robert J. Amdur, Christopher G. Morris, Donald C. Lanza, Peter T. Dziegielewski, Jeb M. Justice, Brian C. Lobo, Natali...> ;Head & Neck. 2019 Mar 25
15 citations
Benefit of continuous treatment for responders with newly diagnosed multiple myeloma in the randomized FIRST trial
Nizar J. Bahlis, Alessandro Corso, Lars-Olof Mügge, Shen Zx, Pierre Desjardins, Stoppa Am, Olivier Decaux, T de Revel, Miquel Granell, Gerald Marit, Hareth Nahi, Hilde...> ;Leukemia. 2017 Apr 4
490 citations
Crizanlizumab for the Prevention of Pain Crises in Sickle Cell Disease.
Kenneth I. Ataga, Abdullah Kutlar, Julie Kanter, Darla K. Liles, Rodolfo D. Cançado, Joao Ricardo Friedrisch, Troy H. Guthrie, Jennifer Knight-Madden, Ofelia A. Alvare...> ;The New England Journal of Medicine. 2017 Feb 2
27 citations
Ramucirumab With Eribulin Versus Eribulin in Locally Recurrent or Metastatic Breast Cancer Previously Treated With Anthracycline and Taxane Therapy: A Multicenter, Ran...
Denise A. Yardley, James Reeves, E. Claire Dees, Cynthia R. C. Osborne, Devchand Paul, Foluso O. Ademuyiwa, Hatem Soliman, Troy Guthrie, Jay Andersen, Lea Krekow, Jana...> ;Clinical Breast Cancer. 2016 Dec 1
47 citations
Phase II study of vemurafenib followed by ipilimumab in patients with previously untreated BRAF-mutated metastatic melanoma
Asim Amin, David H. Lawson, April K.S. Salama, Henry B. Koon, Troy H. Guthrie, Sajeve S. Thomas, Steven J. O'Day, Montaser Shaheen, Bin Zhang, Stephen Francis, F. Step...> ;Journal for Immunotherapy of Cancer. 2016 Aug 16
1603 citations
Talimogene Laherparepvec Improves Durable Response Rate in Patients With Advanced Melanoma
Robert H.I. Andtbacka, Howard L. Kaufman, Frances A. Collichio, Thomas Amatruda, Neil Senzer, Jason Chesney, Keith A. Delman, Lynn E. Spitler, Igor Puzanov, Sanjiv S. ...> ;Journal of Clinical Oncology. 2015 May 26
25 citations
Changing paradigms in management of metastatic Castration Resistant Prostate Cancer (mCRPC)
Eva Gupta, Troy H. Guthrie, Winston Tan> ;BMC Urology. 2014 Jul 25
3 citations
Acute lymphoblastic leukaemia in a Jehovah's Witness: a management dilemma.
Louise Zhou, Amr Mohsen, Mohammad A. Khan, Troy Guthrie> ;Journal of Chemotherapy. 2014 May 9
4 citations
A randomized, double-blind, placebo-controlled study to assess QTc interval prolongation of standard dose aflibercept in cancer patients treated with docetaxel.
Pierre Maison-Blanche, Jan B. Vermorken, Tuncay Göksel, Jean-Pascal Machiels, Sanjiv S. Agarwala, Sylvie Rottey, Gedske Daugaard, Constantin Volovat, Max E. Scheulen, ...> ;Journal of Cardiovascular Pharmacology. 2013 Jun 1
3 citations
Breast cancer in sickle cell disease.
Eva Gupta, Troy H. Guthrie> ;The Breast Journal. 2012 Nov 1
13 citations
Breast Cancer and HIV in the Era of Highly Active Antiretroviral Therapy: Two Case Reports and Review of the Literature
Naeem Latif, Fauzia Rana, Troy H. Guthrie> ;The Breast Journal. 2011 Jan 1
900 citations
Ipilimumab monotherapy in patients with pretreated advanced melanoma: a randomised, double-blind, multicentre, phase 2, dose-ranging study
, , , , , , , , , , , , , , , > ;The Lancet. Oncology. 2010 Feb 1
19 citations
Quantifying the reduction in immunoglobulin use over time in patients with chronic immune thrombocytopenic purpura receiving romiplostim (AMG 531).
Vinod Pullarkat, Terry Gernsheimer, Jeffrey S. Wasser, Adrian C. Newland, Troy H. Guthrie, Joost T. M. de Wolf, Ron Stewart, Dietmar Berger> ;American Journal of Hematology. 2009 Aug 1
25 citations
Predictors of Toxicity and Toxicity Profile of Adjuvant Chemotherapy in Elderly Breast Cancer Patients
Praveen Garg, Fauzia Rana, Ruchi Gupta, Elena M. Buzaianu, Troy H. Guthrie> ;The Breast Journal. 2009 Jul 1
4 citations
Refractory idiopathic pure red cell aplasia complicated by immune thrombocytopenia successfully treated with subcutaneous alemtuzumab.
Dat C. Pham, Troy H. Guthrie, Bruce Villas, Elaine Salazar> ;American Journal of Hematology. 2008 Jul 1
Role of performance status and comorbidities as predictors of toxicity of adjuvant chemotherapy in elderly breast cancer patients.
Garg P, Rana F, Guthrie TH> ;J. Clin. Oncol.. 2008-05-20
596 citations
Efficacy of romiplostim in patients with chronic immune thrombocytopenic purpura: a double-blind randomised controlled trial
David J. Kuter, James B. Bussel, Roger M. Lyons, Vinod Pullarkat, Terry Gernsheimer, Francis M. Senecal, Louis M. Aledort, James N. George, Craig M. Kessler, Miguel A....> ;Lancet. 2008 Feb 2
73 citations
Phase II Trial of Idiotype Vaccination in Previously Treated Patients With Indolent Non-Hodgkin’s Lymphoma Resulting in Durable Clinical Responses
Charles H. Redfern, Troy H. Guthrie, Alberto Bessudo, John J. Densmore, Peter Holman, Nalini Janakiraman, John P. Leonard, Richard Levy, Richard G. Just, Mitchell R. S...> ;Journal of Clinical Oncology. 2006 Jul 1
472 citations
Randomized Phase III Trial Comparing Irinotecan/Cisplatin With Etoposide/Cisplatin in Patients With Previously Untreated Extensive-Stage Disease Small-Cell Lung Cancer
Nasser H. Hanna, Paul A. Bunn, Corey Langer, Lawrence H. Einhorn, Troy H. Guthrie, Thaddeus Beck, Rafat Ansari, Peter M. Ellis, Michael Byrne, Mark E. Morrison, Subram...> ;Journal of Clinical Oncology. 2006 May 1
Outcomes in 708 resected stage I non-small cell lung cancer (NSCLC) subjects and a prognostic index for relapse.
Goodgame B, Viswanathan A, Pillot G, Gao F, Morgensztern D, Bradley J, Guthrie T, Battafarano R, Govindan R> ;J. Clin. Oncol.. 2005-06-01
17 citations
Intramedullary spinal cord metastasis in breast cancer: clinical features, diagnosis, and therapeutic consideration.
Augusto E. Villegas, Troy H. Guthrie> ;The Breast Journal. 2004 Nov 1
Successful anti-Id T-cell responses to Id-KLH immunotherapy in B-cell depleted patients with follicular lymphoma (FL) may prolong TTP after rituximab: Phase II trial o...
Koc ON, Redfern C, Wiernik P, Rosenfelt F, Winter J, Guthrie T, Kaplan L, Holman P, Densmore J, Hainsworth J> ;J. Clin. Oncol.. 2004-07-15
54 citations
Initial management of immune thrombocytopenic purpura in adults: A randomized controlled trial comparing intermittent anti-D with routine care
James N. George, Gary E. Raskob, Sara K. Vesely, Dennis Moore, Roger M. Lyons, Everardo Cobos, Brenda L. Towell, Panpit Klug, Troy H. Guthrie> ;American Journal of Hematology. 2003 Nov 1
16 citations
HIV-associated primary cervical non-Hodgkin's lymphoma and two other cases of primary pelvic non-Hodgkin's lymphoma.
Dat C. Pham, Troy H. Guthrie, Boniface U. Ndubisi> ;Gynecologic Oncology. 2003 Jul 1
75 citations
Pharmacokinetics of doxorubicin administered i.v. as Myocet (TLC D-99; liposome-encapsulated doxorubicin citrate) compared with conventional doxorubicin when given in ...
Christine E. Swenson, Lois E. Bolcsak, Gerald Batist, Troy H. Guthrie, Katherine Tkaczuk, Harold Boxenbaum, Lauri Welles, Shein-Chung Chow, Rupinder Bhamra, Philip Cha...> ;Anti-Cancer Drugs. 2003 Mar 1
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Professional Memberships

American Society of Clinical Oncology - ASCO
Member

Hospital Affiliations

Ascension St. Vincent's RiversideJacksonville, Florida
Ascension St. Vincent's SouthsideJacksonville, Florida
Baptist Medical Center JacksonvilleJacksonville, Florida
Baptist Medical Center NassauFernandina Beach, Florida
HCA Florida Memorial Hospital Jacksonville, Florida
UF Health JacksonvilleJacksonville, Florida