UlfHenningBeierMD

Pediatric Nephrology • Philadelphia, PA

Assistant Professor, Pediatrics, Perelman School of Medicine

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Office
3401 Civic Center Blvd
Children's Hospital Of Philadelphia - Nephrology
Philadelphia, PA 19104
Phone+1 215-590-2449

Fax+1 215-590-0425
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Education & Training

Children's Hospital of PhiladelphiaFellowship, Pediatric Nephrology, 2008 - 2011
University of Illinois College of Medicine at ChicagoResidency, Pediatrics, 2005 - 2008
Univ Kiel- Christian- Albrechts- Fac MedClass of 2004

Certifications & Licensure

PA State Medical License 2008 - 2022
NJ State Medical License 2016 - 2021
IL State Medical License 2005 - 2008

Publications & Presentations

PubMed

The poly(C)-binding protein Pcbp2 is essential for CD4T cell activation and proliferation.
Massimo Martinelli, Gabrielle Aguilar, David S M Lee, Andrew Kromer, Nhu Nguyen, Benjamin J Wilkins, Tatiana Akimova, Ulf H Beier, Louis R Ghanem> ;Iscience. 2023 Jan 20
2 citations
Thermogenic T cells: a cell therapy for obesity?
Ulf H Beier, Daniel J Baker, Joseph A Baur> ;American Journal of Physiology. Cell Physiology. 2022 Jun 1
17 citations
Kynurenine induces T cell fat catabolism and has limited suppressive effects in vivo.
Peter J Siska, Jing Jiao, Carina Matos, Katrin Singer, Raffaela S Berger, Katja Dettmer, Peter J Oefner, Michelle D Cully, Zhonglin Wang, William J QuinnIII, Kristen N...> ;Ebiomedicine. 2021 Dec 1
7 citations
Obesity-related IL-18 Impairs T-Regulatory Cell Function and Promotes Lung Ischemia-Reperfusion Injury.
Tatiana Akimova, Tianyi Zhang, Lanette M Christensen, Zhonglin Wang, Rongxiang Han, Dmitry Negorev, Arabinda Samanta, Isaac E Sasson, Trivikram Gaddapara, Jing Jiao, L...> ;American Journal of Respiratory and Critical Care Medicine. 2021 Nov 1
1 citations
Transcriptional regulation of T cell metabolism and metabolic control of T cell gene expression.
Kimberly Veliz, Ulf H. Beier> ;Current Opinion in Genetics & Development. 2021 Oct 1
3 citations
Distinct Bioenergetic Features of Human Invariant Natural Killer T Cells Enable Retained Functions in Nutrient-Deprived States.
Priya Khurana, Chakkapong Burudpakdee, Stephan A. Grupp, Ulf H. Beier, David M. Barrett, Hamid Bassiri> ;Frontiers in Immunology. 2021 Aug 9
10 citations
HDAC2 targeting stabilizes the CoREST complex in renal tubular cells and protects against renal ischemia/reperfusion injury.
David D. Aufhauser, Paul T. Hernandez, Seth J. Concors, Ciaran O’Brien, Zhonglin Wang, Douglas R. Murken, Arabinda Samanta, Ulf H. Beier, Lauren N. Krumeich, Tricia R....> ;Scientific Reports. 2021 Apr 27
6 citations
A Biological Circuit Involving Mef2c, Mef2d, and Hdac9 Controls the Immunosuppressive Functions of CD4+Foxp3+ T-Regulatory Cells.
Eros Di Giorgio, Liqing Wang, Yan Xiong, Lanette M Christensen, Tatiana Akimova, Rongxiang Han, Arabinda Samanta, Matteo Trevisanut, Claudio Brancolini, Ulf H. Beier, ...> ;Frontiers in Immunology. 2021 Jan 1
120 citations
Lactate Limits T Cell Proliferation via the NAD(H) Redox State.
William J. Quinn, Jing Jiao, Tara TeSlaa, Jason Stadanlick, Zhonglin Wang, Liqing Wang, Tatiana Akimova, Alessia Angelin, Patrick M. Schäfer, Michelle D. Cully, Caroli...> ;Cell Reports. 2020 Dec 15
11 citations
MEF2D sustains activation of effector Foxp3+ Tregs during transplant survival and anticancer immunity.
Eros Di Giorgio, Liqing Wang, Yan Xiong, Tatiana Akimova, Lanette M Christensen, Rongxiang Han, Arabinda Samanta, Matteo Trevisanut, Tricia R. Bhatti, Ulf H. Beier, Wa...> ;The Journal of Clinical Investigation. 2020 Dec 1
6 citations
Tissue metabolic profiling shows that saccharopine accumulates during renal ischemic-reperfusion injury, while kynurenine and itaconate accumulate in renal allograft r...
Ulf H. Beier, Erum A. Hartung, Seth J. Concors, Paul T. Hernandez, Zhonglin Wang, Caroline Perry, Joseph A. Baur, Michelle R. Denburg, Wayne W. Hancock, Terence P. Gad...> ;Metabolomics. 2020 May 4
Vecuronium- and Esmolol-Induced Pseudohypernatremia Due to Drug Interference With Ion-Selective Electrodes
Tracey G. Polsky, Eloise Salmon, Sarah S. Welsh, Derick Lim, Sheng Feng, Lance Ballester, Abdulla M. Ehlayel, Jennifer Hewlett, Michelle R. Denburg, Donald L. Boyer, U...> ;Critical Care Explorations. 2020 Jan 29
40 citations
HDAC10 deletion promotes Foxp3+ T-regulatory cell function.
Satinder Dahiya, Ulf H. Beier, Liqing Wang, Rongxiang Han, Jing Jiao, Tatiana Akimova, Alessia Angelin, Douglas C. Wallace, Wayne W. Hancock> ;Scientific Reports. 2020 Jan 16
35 citations
Inhibiting the coregulator CoREST impairs Foxp3+ Treg function and promotes antitumor immunity
Yan Xiong, Liqing Wang, Eros Di Giorgio, Tatiana Akimova, Ulf H. Beier, Rongxiang Han, Matteo Trevisanut, Jay H. Kalin, Philip A. Cole, Wayne W. Hancock> ;The Journal of Clinical Investigation. 2020 Apr 1
87 citations
A small molecule G6PD inhibitor reveals immune dependence on pentose phosphate pathway
Jonathan M. Ghergurovich, Juan Carlos García-Cañaveras, Joshua Wang, Emily Schmidt, Zhaoyue Zhang, Tara TeSlaa, Harshel Patel, Li Chen, Emily C. Britt, Marta Piqueras-...> ;Nature Chemical Biology. 2020 Jan 1
9 citations
Complementary Roles of GCN5 and PCAF in Foxp3+ T-Regulatory Cells
Yujie Liu, Chunrong Bao, Liqing Wang, Rongxiang Han, Ulf H. Beier, Tatiana Akimova, Philip A. Cole, Sharon Y.R. Dent, Wayne W. Hancock> ;Cancers. 2019 Apr 18
144 citations
Human tumor-associated monocytes/macrophages and their regulation of T cell responses in early-stage lung cancer
Sunil Singhal, Jason Stadanlick, Michael Annunziata, Abhishek Rao, Pratik Bhojnagarwala, Shaun O'Brien, Edmund K. Moon, Edward Cantu, Gwenn Danet-Desnoyers, Hyun-Jeong...> ;Science Translational Medicine. 2019 Feb 13
27 citations
Sirtuin-1 in immunotherapy: A Janus-headed target.
Sakshum Chadha, Liqing Wang, Wayne W. Hancock, Ulf H. Beier> ;Journal of Leukocyte Biology. 2019 Aug 1
27 citations
Loss of HDAC6 alters gut microbiota and worsens obesity.
Arnon D. Lieber, Ulf H. Beier, Haiyan Xiao, Benjamin J. Wilkins, Jing Jiao, Xinmin S. Li, Rebecca C. Schugar, Christopher M. Strauch, Zeneng Wang, J. Mark Brown, Stanl...> ;FASEB Journal. 2019 Jan 1
4 citations
Differential chemokine expression patterns in tonsillar disease.
M Mandapathil, Ulf H. Beier, H Graefe, B Kröger, Jürgen Hedderich, Steffen Maune, Jens E. Meyer> ;Acta Otorhinolaryngologica Italica. 2018 Aug 1
Histone/protein Deacetylase Inhibitor Therapy for Enhancement of Foxp3+ T‐Regulatory Cell Function Post‐Transplantation
M H Levine, L Wang, U H Beier> ;American journal of transplantation.
31 citations
Human neutrophils can mimic myeloid-derived suppressor cells (PMN-MDSC) and suppress microbead or lectin-induced T cell proliferation through artefactual mechanisms.
Dmitri Negorev, Ulf H. Beier, Tianyi Zhang, Jon G. Quatromoni, Pratik Bhojnagarwala, Steven M. Albelda, Sunil Singhal, Evgeniy Eruslanov, Falk W. Lohoff, Matthew H. Le...> ;Scientific Reports. 2018 Feb 16
4 citations
Apoptotic Regulatory T Cells Retain Suppressive Function through Adenosine.
Ulf H. Beier> ;Cell Metabolism. 2018 Jan 9
58 citations
Histone/Protein Deacetylase 11 Targeting Promotes Foxp3+ Treg Function.
Jianbing Huang, Liqing Wang, Satinder Dahiya, Ulf H. Beier, Rongxiang Han, Arabinda Samanta, Joel A. Bergman, Eduardo M. Sotomayor, Edward Seto, Alan P. Kozikowski, Wa...> ;Scientific Reports. 2017 Aug 17
46 citations
Human lung tumor FOXP3 + Tregs upregulate four “Treg-locking” transcription factors
Tatiana Akimova, Tianyi Zhang, Dmitri Negorev, Sunil Singhal, Jason Stadanlick, Abhishek Rao, Michael Annunziata, Matthew H. Levine, Ulf H. Beier, Joshua M. Diamond, J...> ;JCI Insight. 2017 Aug 18
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