VernCJuelMD

Neurology • Durham, NC

Neuromuscular Medicine, Neurophysiology

Associate Professor of Neurology, Duke University School of Medicine

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Office
40 Duke Medicine Cir
Durham, NC 27710
Phone+1 919-684-5422

Fax+1 919-660-3853
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Education & Training

University of Illinois College of MedicineClass of 1989

Certifications & Licensure

NC State Medical License 1990 - 2024
VA State Medical License 1994 - 2024
American Board of Psychiatry and Neurology Neurology
American Board of Psychiatry and Neurology Clinical Neurophysiology
American Board of Psychiatry and Neurology Neuromuscular Medicine
American Board of Electrodiagnostic MedicineElectromyography

Awards, Honors, & Recognition

CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2013

Clinical Trials

Treatment Use of 3,4-Diaminopyridine
No longer available

Publications & Presentations

PubMed

1 citations
Pregnancy in Seronegative Myasthenia Gravis: A Single-Center Case Series.
Yohei Harada, Margaret Bettin, Vern C Juel, Janice M Massey, Donald B Sanders> ;Journal of Clinical Neuromuscular Disease. 2023 Dec 1
2 citations
Pregnancy in MuSK-positive myasthenia gravis: A single-center case series.
Yohei Harada, Margaret Bettin, Vern C Juel, Lisa D Hobson-Webb, Shruti M Raja, Donald B Sanders, Janice M Massey> ;Muscle & Nerve. 2023 Jul 1
3 citations
Clinicoserological insights into patients with immune checkpoint inhibitor-induced myasthenia gravis.
Gianvito Masi, Minh C Pham, Tabitha Karatz, Sangwook Oh, Aimee S Payne, Richard J Nowak, James F Howard Jr, Jeffrey T Guptill, Vern C Juel, Kevin C O'Connor> ;Annals of Clinical and Translational Neurology. 2023 May 1
2 citations
The Duke Myasthenia Gravis Clinic Registry: II. Analysis of outcomes.
Donald B Sanders, Michael W Lutz, Shruti M Raja, Vern C Juel, Jeffrey T Guptill, Lisa D Hobson-Webb, Janice M Massey> ;Muscle & Nerve. 2023 Apr 1
Clinical Reasoning: A 36-Year-Old Man With Asymmetric Muscle Weakness.
Yohei Harada, Shih-Hsiu Wang, Vern C Juel> ;Neurology. 2022 Dec 5
6 citations
First-in-Human Clinical Trial to Assess the Safety, Tolerability and Pharmacokinetics of Single Doses of NTM-1633, a Novel Mixture of Monoclonal Antibodies against Bot...
S M Raja, J T Guptill, V C Juel, E B Walter, M Cohen-Wolkowiez, H Hill, E Sendra, B Hauser, P Jackson, M Tomic, Y Espinoza, G K Swamy> ;Antimicrobial Agents and Chemotherapy. 2022 Apr 19
A Case of Probable Multifocal Motor Neuropathy With Clinical Stability for Ten Years After a Single Treatment of Rituximab.
Natalia L Gonzalez, Vern C Juel, Saša A Živković> ;Journal of Clinical Neuromuscular Disease. 2022 Mar 1
79 citations
Consensus disease definitions for neurologic immune-related adverse events of immune checkpoint inhibitors.
Amanda C. Guidon, Leeann B Burton, Bart K Chwalisz, James M. Hillis, Teilo H Schaller, Anthony A. Amato, Allison Betof Warner, Priscilla K. Brastianos, Tracey A. Cho, ...> ;Journal for Immunotherapy of Cancer. 2021 Jul 1
7 citations
Safety, Tolerability, and Pharmacokinetics of NTM-1632, a Novel Mixture of Three Monoclonal Antibodies against Botulinum Toxin B.
Jeffrey T. Guptill, Shruti M. Raja, Vern C. Juel, Emmanuel B. Walter, Michael Cohen-Wolkowiez, Heather Hill, Eli A. Sendra, B Hauser, Pearce Jackson, Geeta K. Swamy> ;Antimicrobial Agents and Chemotherapy. 2021 Jun 17
15 citations
The Duke myasthenia gravis clinic registry: I. Description and demographics.
Donald B. Sanders, Shruti M. Raja, Jeffrey T. Guptill, Lisa D. Hobson-Webb, Vern C. Juel, Janice M. Massey> ;Muscle & Nerve. 2021 Feb 1
65 citations
Effect of Ezogabine on Cortical and Spinal Motor Neuron Excitability in Amyotrophic Lateral Sclerosis: A Randomized Clinical Trial
, , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , > ;JAMA Neurology. 2021 Feb 1
2 citations
Reduced plasmablast frequency is associated with seronegative myasthenia gravis.
Jeffrey T. Guptill, Richard Barfield, Cliburn Chan, Melissa A. Russo, Doug Emmett, Shruti M. Raja, Janice M. Massey, Vern C. Juel, Lisa D. Hobson-Webb, Karissa L. Gabl...> ;Muscle & Nerve. 2020 Dec 24
11 citations
KNOWLEDGE AND PERCEPTIONS OF THE COVID-19 PANDEMIC AMONG PATIENTS WITH MYASTHENIA GRAVIS
Yingkai Li, C Douglas Emmett, Marjan Cobbaert, Donald B. Sanders, Vern C. Juel, Lisa D. Hobson-Webb, Janice M. Massey, Karissa L. Gable, Shruti M. Raja, Natalia Gonzal...> ;Muscle & Nerve. 2021 Mar 1
17 citations
Imbalance in T follicular helper cells producing IL-17 promotes pro-inflammatory responses in MuSK antibody positive myasthenia gravis
Yingkai Li, Jeffrey T. Guptill, Melissa A. Russo, James F. Howard, Janice M. Massey, Vern C. Juel, Lisa D. Hobson-Webb, Doug Emmett, Manisha Chopra, Shruti M. Raja, We...> ;Journal of Neuroimmunology. 2020 Aug 15
16 citations
Consistent improvement with eculizumab across muscle groups in myasthenia gravis
Renato Mantegazza, Fanny O'Brien, Marcus Yountz, James F. Howard, Claudio Mazia, Miguel Wilken, Fabio Barroso, Juliet Saba, Marcelo Rugiero, Mariela Bettini, Marcelo C...> ;Annals of Clinical and Translational Neurology. 2020 Aug 1
9 citations
Inhibition of the transcription factor ROR-γ reduces pathogenic Th17 cells in acetylcholine receptor antibody positive myasthenia gravis.
John S. Yi, Melissa A. Russo, Shruti M. Raja, Janice M. Massey, Vern C. Juel, Jay Shin, Lisa D. Hobson-Webb, Karissa L. Gable, Jeffrey T. Guptill> ;Experimental Neurology. 2020 Mar 1
10 citations
Clinical outcome measures following plasma exchange for MG exacerbation.
Shruti M. Raja, James F. Howard, Vern C. Juel, Janice M. Massey, Manisha Chopra, Jeffrey T. Guptill> ;Annals of Clinical and Translational Neurology. 2019 Oct 1
4 citations
Validation of the triple timed up-and-go test in Lambert-Eaton myasthenia.
Shruti M. Raja, Donald B. Sanders, Vern C. Juel, Yadollah Harati, A. Gordon Smith, Robert M. Pascuzzi, David P. Richman, Angie Wu, Kathy L. Aleš, Laura R. Jacobus, Dav...> ;Muscle & Nerve. 2019 Sep 1
7 citations
Efgartigimod: A novel antibody depletion therapy in myasthenia gravis.
Amanda C. Guidon, Vern C. Juel> ;Neurology. 2019 Jun 4
2 citations
Repetitive nerve stimulation testing in myasthenic crisis
Vern C. Juel> ;Muscle & Nerve. 2019 May 1
105 citations
Long-term effect of thymectomy plus prednisone versus prednisone alone in patients with non-thymomatous myasthenia gravis: 2-year extension of the MGTX randomised trial.
, , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , ,...> ;The Lancet. Neurology. 2019 Mar 1
25 citations
Tacrolimus inhibits Th1 and Th17 responses in MuSK-antibody positive myasthenia gravis patients.
Yingkai Li, Jeffrey T. Guptill, Melissa A. Russo, Janice M. Massey, Vern C. Juel, Lisa D. Hobson-Webb, James F. Howard, Manisha Chopra, Weibin Liu, John S. Yi> ;Experimental Neurology. 2019 Feb 1
7 citations
Single fiber electromyography.
Vern C. Juel> ;Handbook of Clinical Neurology. 2019 Jan 1
8 citations
Clinical neurophysiology of neuromuscular junction disease.
Vern C. Juel> ;Handbook of Clinical Neurology. 2019 Jan 1
10 citations
Circulating microRNA plasma profile in MuSK+ myasthenia gravis
Liis Sabre, Jeffrey T. Guptill, Melissa A. Russo, Vern C. Juel, Janice M. Massey, James F. Howard, Lisa D. Hobson-Webb, Anna Rostedt Punga> ;Journal of Neuroimmunology. 2018 Dec 15
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Journal Articles

Effect of Ezogabine on Cortical and Spinal Motor Neuron Excitability in Amyotrophic Lateral Sclerosis
Brian J Wainger, Nicholas J Maragakis, Richard Bedlack, Namita A Goyal, Seward B Rutkove, Michael H Rivner, Stephen A Goutman, Shafeeq S Ladha, Elizabeth A Mauricio, R..., JAMA Neurology