VincentChungMD

Oncology • Duarte, CA

Gastrointestinal Cancer

Clinical Professor

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Office
Medical Oncology and Therapeutics Research
1500 East Duarte Road
Duarte, CA 91010
Phone+1 626-256-4673

Fax+1 626-301-8233
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Education & Training

Los Angeles County-Harbor-UCLA Medical Center 1Fellowship, Hematology and Medical Oncology, 2002 - 2005
California Pacific Medical CenterResidency, Internal Medicine, 1998 - 2002
University of Tennessee Health Science Center College of MedicineClass of 1998

Certifications & Licensure

CA State Medical License 1999 - 2025
American Board of Internal Medicine Internal Medicine
American Board of Internal Medicine Medical Oncology

Awards, Honors, & Recognition

Top Doctors:LA Area Castle Connolly, 2013

Clinical Trials

Cyclophosphamide With or Without Celecoxib in Treating Patients With Recurrent or Persistent Ovarian Epithelial, Fallopian Tube, or Primary Peritoneal Cancer Start of enrollment: 2003 Dec 22
Completed
Phase 2
Dasatinib in Treating Patients With Stage IV Pancreatic Cancer Start of enrollment: 2007 Sep 01
Terminated
Phase 2
Vaccine Therapy in Treating Patients With Colorectal, Stomach, or Pancreatic Cancer Start of enrollment: 2011 Oct 01
Completed
Phase 1
Everolimus and Combination Chemotherapy in Treating Patients With Metastatic Stomach or Esophageal Cancer Start of enrollment: 2012 Feb 01
Completed
Phase 1, Phase 2
Veliparib, Paclitaxel, and Carboplatin in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery and Liver or Kidney Dysfunction Start of enrollment: 2011 Jun 20
Active, not recruiting
Phase 1
Romidepsin in Treating Patients With Lymphoma, Chronic Lymphocytic Leukemia, or Solid Tumors With Liver Dysfunction Start of enrollment: 2012 Jun 12
Active, not recruiting
Phase 1
Selumetinib and Akt Inhibitor MK2206 or mFOLFOX Therapy Comprising Oxaliplatin and Fluorouracil in Treating Patients With Metastatic Pancreatic Cancer Previously Treated With Chemotherapy Start of enrollment: 2012 Aug 01
Completed
Phase 2
Immunotherapy Study in Borderline Resectable or Locally Advanced Unresectable Pancreatic Cancer Start of enrollment: 2013 May 01
Terminated
Phase 3
Phase I Study of LB-100 With Docetaxel in Solid Tumors Start of enrollment: 2013 Feb 01
Completed
Phase 1
Dabrafenib in Treating Patients With Solid Tumors and Kidney or Liver Dysfunction Start of enrollment: 2013 Aug 23
Terminated
Phase 1
64Cu DOTA-Trastuzumab PET/CT in Studying Patients With Gastric Cancer Start of enrollment: 2014 Nov 19
Active, not recruiting
Not Applicable
Study of Trametinib in Advanced Cancer Patients With Hepatic Dysfunction Start of enrollment: 2013 Dec 01
Trametinib in Treating Patients With Advanced Cancer With or Without Hepatic Dysfunction Start of enrollment: 2014 Mar 10
Active, not recruiting
Phase 1
Testing the Addition of Pembrolizumab, an Immunotherapy Cancer Drug to Olaparib Alone as Therapy for Patients With Pancreatic Cancer That Has Spread With Inherited BRCA Mutations Start of enrollment: 2021 Feb 22
Recruiting
Phase 2
Lenvatinib and Pembrolizumab Maintenance Therapy for the Treatment of Patients of Advanced Unresectable Pancreatic Cancer Start of enrollment: 2021 Jul 21
Recruiting
Phase 2
A Study of TAK-500 With or Without Pembrolizumab in Adults With Select Locally Advanced or Metastatic Solid Tumors Start of enrollment: 2022 Apr 14
Recruiting
Phase 1, Phase 2
Roles: Principal Investigator
A Study of ELI-002 in Subjects With KRAS Mutated Pancreatic Ductal Adenocarcinoma (PDAC) and Other Solid Tumors Start of enrollment: 2021 Oct 04
Active, not recruiting
Phase 1
Roles: Principal Investigator, Contact
AOH1996 for the Treatment of Refractory Solid Tumors Start of enrollment: 2022 Aug 12
Active, not recruiting
Phase 1
Roles: Principal Investigator, Contact
Chemoradiation and Pembrolizumab Followed by Pembrolizumab and Lenvatinib Before Surgery for the Treatment of Non-metastatic Esophageal or Esophageal/Gastroesophageal Junction Cancer Start of enrollment: 2022 Jan 25
Active, not recruiting
Phase 2
Roles: Principal Investigator, Contact
A Study of ELI-002 7P in Subjects With KRAS/NRAS Mutated Solid Tumors Start of enrollment: 2023 Apr 14
Recruiting
Phase 1, Phase 2
Roles: Contact, Principal Investigator
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Publications & Presentations

PubMed

Outcome prioritization and preferences among older adults with cancer starting chemotherapy in a randomized clinical trial.
Enrique Soto-Perez-de-Celis, William Dale, Vani Katheria, Heeyoung Kim, Marwan Fakih, Vincent M Chung, Dean Lim, Joanne Mortimer, Leana Cabrera Chien, Kemeberly Charle...> ;Cancer. 2024 Apr 17
Neoadjuvant treatment for pancreatic cancer: Controversies and advances.
Douglas Dias E Silva, Vincent Chung> ;Cancer Treatment and Research Communications. 2024 Mar 11
Pancreatic Adenocarcinoma: Real World Evidence of Care Delivery in AccessHope Data.
Afsaneh Barzi, Angela J Kim, Crystal K Liang, Howard West, D Wong, Carol Wright, Nitya Nathwani, Catherine M Vasko, Vincent Chung, Douglas A Rubinson, Todd Sachs> ;Journal of Personalized Medicine. 2023 Sep 15
4 citations
Small molecule targeting of transcription-replication conflict for selective chemotherapy.
Long Gu, Min Li, Caroline M Li, Pouya Haratipour, Robert Lingeman, Jennifer Jossart, Margarita Gutova, Linda Flores, Caitlyn Hyde, Nikola Kenjić, Haiqing Li, Vincent C...> ;Cell Chemical Biology. 2023 Oct 19
1 citations
Integrating Early-Stage Drug Development with Clinical Networks; Challenges and Opportunities: The City of Hope Developing Experience.
Miguel A Villalona-Calero, Jyoti Malhotra, Vincent Chung, Yan Xing, Stacy W Gray, Heather Hampel, Stephen Gruber, Kevin McDonnell> ;Journal of Clinical Medicine. 2023 Jun 15
5 citations
Advances in Radiation Oncology for Pancreatic Cancer: An Updated Review.
Jason Liu, Percy Lee, Heather M McGee, Vincent Chung, Laleh Melstrom, Gagandeep Singh, Mustafa Raoof, Arya Amini, Yi-Jen Chen, Terence M Williams> ;Cancers. 2022 Nov 22
3 citations
Endothelin-axis antagonism enhances tumor perfusion in pancreatic cancer.
Shailendra K Gautam, Vipin Dalal, Balasrinivasa R Sajja, Suprit Gupta, Mansi Gulati, Nidhi V Dwivedi, Abhijit Aithal, Jesse L Cox, Satyanarayana Rachagani, Yutong Liu,...> ;Cancer Letters. 2022 Sep 28
3 citations
Biomarker analysis from a phase II multi-institutional study of nivolumab in patients with advanced refractory biliary tract cancer.
Dae Won Kim, Vincent Chung, Olatunji B Alese, Bassel F El-Rayes, Daneng Li, Wungki Park, Richard D Kim, Kim, Y., Kovari, B.> ;European Journal of Cancer. 2022 Nov 1
4 citations
A randomized phase II study of SM-88 plus methoxsalen, phenytoin, and sirolimus in patients with metastatic pancreatic cancer treated in the second line and beyond.
Marcus S Noel, Semmie Kim, Marion L Hartley, Steve Wong, Vincent J Picozzi, Harry Staszewski, Dae Won Kim, Jan M Van Tornout, Philip Agop Philip, Vincent Chung, Allyso...> ;Cancer Medicine. 2022 Nov 1
3 citations
B7H6 Serves as a Negative Prognostic Marker and an Immune Modulator in Human Pancreatic Cancer.
Zheng Zhu, Kun-Yu Teng, Jian Zhou, Yunyun Xu, Lifeng Zhang, Hua Zhao, Xueguang Zhang, Lei Tian, Zhiyao Li, Ting Lu, Shoubao Ma, Zhenlong Li, Zhenyu Dai, Jing Wang, Xin...> ;Frontiers in Oncology. 2022 Jan 1
104 citations
First-in-human phase 1 study of the anti–TIGIT antibody vibostolimab as monotherapy or with pembrolizumab for advanced solid tumors, including non–small cell lung cancer
Jiaxin Niu, Corinne Maurice-Dror, Dongwhane Lee, Dai Woo Kim, Adnan Nagrial, Mark Voskoboynik, H.C. Chung, K.F. Mileham, Ulka N. Vaishampayan, Drew W. Rasco, Talia Gol...> ;Annals of Oncology. 2021 Nov 17
16 citations
Improving Palliative Care and Quality of Life in Pancreatic Cancer Patients.
Vincent Chung, Virginia Sun, Nora H. Ruel, Thomas J. Smith, Betty Ferrell> ;Journal of Palliative Medicine. 2021 Oct 26
177 citations
Geriatric Assessment-Driven Intervention (GAIN) on Chemotherapy-Related Toxic Effects in Older Adults With Cancer: A Randomized Clinical Trial.
, , , , , , , , , , , , , , , , , > ;JAMA Oncology. 2021 Sep 30
6 citations
Patterns of Whole Exome Sequencing in Resected Cholangiocarcinoma.
Lucas W. Thornblade, Paul Wong, Daneng Li, Susanne G. Warner, Sue Chang, Mustafa Raoof, Jonathan Kessler, Arya Amini, James Lin, Vincent Chung, Gagandeep Singh, Yuman ...> ;Cancers. 2021 Aug 12
8 citations
Evaluation of Somatic Mutations in Solid Metastatic Pan-Cancer Patients.
, , , , , , , , , , , , , , , , , , , , , , , , , > ;Cancers. 2021 Jun 3
1 citations
Chemotherapy-induced early transient increase and surge of CA 19-9 level in patients with pancreatic Adenocarcinoma✰.
Viet H. Le, Jan Franko, Benjamin Paz, Gagandeep Singh, Vincent Chung> ;Cancer Treatment and Research Communications. 2021 Jan 1
3 citations
Multidisciplinary management of locally advanced pancreatic adenocarcinoma: Biology is King.
Marc A Attiyeh, Arya Amini, Vincent Chung, Laleh G. Melstrom> ;Journal of Surgical Oncology. 2021 May 1
495 citations
Pancreatic adenocarcinoma, Version 2.2021
Margaret A. Tempero, Mokenge P. Malafa, Mahmoud M. Al-Hawary, Stephen W. Behrman, Al B. Benson, Dana Backlund Cardin, E. Gabriela Chiorean, Vincent Chung, Brian G. Czi...> ;Journal of the National Comprehensive Cancer Network. 2021 Apr 1
2 citations
Role of 3D Volumetric and Perfusion Imaging for Detecting Early Changes in Pancreatic Adenocarcinoma.
Syed Rahmanuddin, Ronald L. Korn, Derek Cridebring, Erkut Borazanci, Jordyn Brase, William Boswell, Asma Jamil, Wenli Cai, Aqsa Sabir, Pejman Motarjem, Eugene J. Koay,...> ;Frontiers in Oncology. 2021 Sep 8
8 citations
Using Patient-Reported Outcomes to Describe the Patient Experience on Phase I Clinical Trials.
Ramy Sedhom, Betty Ferrell, Nora Ruel, Marianna Koczywas, Vincent Chung, Thomas J. Smith> ;JNCI Cancer Spectrum. 2020 Aug 14
10 citations
A Palliative Care Intervention for Patients on Phase 1 Studies
Betty Ferrell, Vincent Chung, Mark T. Hughes, Marianna Koczywas, Nilofer S. Azad, Nora Ruel, Louise Knight, Rhonda S. Cooper, Thomas J. Smith> ;Journal of Palliative Medicine. 2021 May 19
2 citations
The effect of sonidegib (LDE225) on the pharmacokinetics of bupropion and warfarin in patients with advanced solid tumours.
Darcy B. Pooler, Dylan B. Ness, John Sarantopoulos, Nicholas Squittieri, Shoba Ravichandran, Carolyn D. Britten, Ravi K. Amaravadi, Ulka N. Vaishampayan, Patricia LoRu...> ;British Journal of Clinical Pharmacology. 2021 Mar 1
256 citations
A Phase 2 Multi-institutional Study of Nivolumab for Patients with Advanced Refractory Biliary Tract Cancer
Richard D. Kim, Vincent Chung, Olatunji B. Alese, Bassell F. El-Rayes, Daneng Li, Taymeyah Al-Toubah, Michael J. Schell, Jun-Min Zhou, Amit Mahipal, Baek Hui Kim, Dae-...> ;JAMA Oncology. 2020 Jun 1
2 citations
Untenable dosing: A common pitfall of modern DLT-targeting Phase I designs in oncology
Paul Frankel, Vincent Chung, Yan Xing, Jeff Longmate, Susan Groshen, Edward M. Newman> ;Current Problems in Cancer. 2020 May 7
8 citations
Model of a Queuing Approach for Patient Accrual in Phase 1 Oncology Studies.
Paul Frankel, Vincent Chung, Joseph Tuscano, Tanya Siddiqi, Sagus Sampath, Jeffrey Longmate, Susan Groshen, Edward M. Newman> ;JAMA Network Open. 2020 May 1
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Lectures

Gene expression profiling of unresectable pancreatic cancer patients treated with gemcitabine, nab-paclitaxel, metformin, and dietary supplements (DS).
ASCO Gastrointestinal Cancers Symposium - San Francisco, CA - 1/24/2020
First-time in-human study of VMD-928, an allosteric and irreversible TrkA selective inhibitor, in patients with solid tumors or lymphoma.
2019 ASCO Annual Meeting - 6/1/2019
A SU2C catalyst randomized phase II trial of pembrolizumab with or without paricalcitol in patients with stage IV pancreatic cancer who have been placed in best possib...
2018 ASCO Annual Meeting - Chicago, Illinois - 06/3/2018

Press Mentions

First Patient Has Received Novel, Potentially Cancer-Stopping PillOctober 19th, 2022
Adding Dietary Supplements to Treatment Impacts Outcomes in Unresectable Pancreatic CancerJanuary 25th, 2020
Dr. Chung on the COMPASS Trial in Pancreatic CancerFebruary 28th, 2019
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