WDavidThomasMD

PubMed

• Structural and molecular analysis of a protective epitope of Lyme disease antigen OspA and antibody interactions.
  Shandilya S, Kurt Yilmaz N, Sadowski A, Monir E, Schiller ZA, Thomas WD, Klempner MS, Schiffer CA, Wang Y> ;J. Mol. Recognit.. 2016-11-16
• Pre-exposure Prophylaxis With OspA-Specific Human Monoclonal Antibodies Protects Mice Against Tick Transmission of Lyme Disease Spirochetes.
  Wang Y, Kern A, Boatright NK, Schiller ZA, Sadowski A, Ejemel M, Souders CA, Reimann KA, Hu L, Thomas WD, Klempner MS> ;J. Infect. Dis.. 2016-07-15
• 10 citations
  Coprevalence of Epstein-Barr Virus, Cytomegalovirus, and Herpes Simplex Virus Type-1 Antibodies Among United States Children and Factors Associated With Their Acquisition
  Amanda S. Delaney, William Thomas, Henry H. Balfour> ;Journal of the Pediatric Infectious Diseases Society. 2015 Dec 1
• A novel in vitro assay to predict neonatal Fc receptor-mediated human IgG half-life.
  Souders CA, Nelson SC, Wang Y, Crowley AR, Klempner MS, Thomas W> ;MAbs. 2015-01-01
• 46 citations
  Age-Specific Prevalence of Epstein-Barr Virus Infection among Minnesota Children Effects of Race/Ethnicity and Family Environment
  Lawrence M. Condon, Laurel E. Cederberg, Mark D. Rabinovitch, Rhoda V. Liebo, Janice C. Go, Amanda S. Delaney, David O. Schmeling, William Thomas, Henry H. Balfour> ;Clinical Infectious Diseases. 2014 May 11
• Resolving self-association of a therapeutic antibody by formulation optimization and molecular approaches.
  Casaz P, Boucher E, Wollacott R, Pierce BG, Rivera R, Sedic M, Ozturk S, Thomas WD, Wang Y> ;MAbs. 2014-01-01
• Identification of a human monoclonal antibody to replace equine diphtheria antitoxin for treatment of diphtheria intoxication.
  Sevigny LM, Booth BJ, Rowley KJ, Leav BA, Cheslock PS, Garrity KA, Sloan SE, Thomas W, Babcock GJ, Wang Y> ;Infect. Immun.. 2013-11-01
• Age-specific prevalence of Epstein-Barr virus infection among individuals aged 6-19 years in the United States and factors affecting its acquisition.
  Balfour HH, Sifakis F, Sliman JA, Knight JA, Schmeling DO, Thomas W> ;J. Infect. Dis.. 2013-10-15
• 51 citations
  Direct effects of Bmi1 on p53 protein stability inactivates oncoprotein stress responses in embryonal cancer precursor cells at tumor initiation
  M Calao, Eric Sekyere, Hongjuan Cui, Belamy B. Cheung, W D Thomas, J. Keating, Jinbiao Chen, A Raif, Jankowski K, N P Davies, M V Bekkum, B Chen, Owen Tan, Tammy Ellis...> ;Oncogene. 2013 Aug 1
• Bruton's tyrosine kinase is required for apoptotic cell uptake via regulating the phosphorylation and localization of calreticulin.
  Byrne JC, Ní Gabhann J, Stacey KB, Coffey BM, McCarthy E, Thomas W, Jefferies CA> ;J. Immunol.. 2013-05-15
• Different patterns of Epstein-Barr virus latency in endemic Burkitt lymphoma (BL) lead to distinct variants within the BL-associated gene expression signature.
  Kelly GL, Stylianou J, Rasaiyaah J, Wei W, Thomas W, Croom-Carter D, Kohler C, Spang R, Woodman C, Kellam P, Rickinson AB, Bell AI> ;J. Virol.. 2013-03-01
• Analytical characterization of a monoclonal antibody therapeutic reveals a three-light chain species that is efficiently removed using hydrophobic interaction chromato...
  Wollacott RB, Casaz PL, Morin TJ, Zhu HL, Anderson RS, Babcock GJ, Que J, Thomas WD, Ozturk SS> ;MAbs. 2013-01-01
• Behavioral, virologic, and immunologic factors associated with acquisition and severity of primary Epstein-Barr virus infection in university students.
  Balfour HH, Odumade OA, Schmeling DO, Mullan BD, Ed JA, Knight JA, Vezina HE, Thomas W, Hogquist KA> ;J. Infect. Dis.. 2013-01-01
• Type 1 fimbrial adhesin FimH elicits an immune response that enhances cell adhesion of Escherichia coli.
  Tchesnokova V, Aprikian P, Kisiela D, Gowey S, Korotkova N, Thomas W, Sokurenko E> ;Infect. Immun.. 2011-10-01
• SIRT1 promotes N-Myc oncogenesis through a positive feedback loop involving the effects of MKP3 and ERK on N-Myc protein stability.
  Marshall GM, Liu PY, Gherardi S, Scarlett CJ, Bedalov A, Xu N, Iraci N, Valli E, Ling D, Thomas W, van Bekkum M, Sekyere E, Jankowski K, Trahair T, Mackenzie KL, Haber...> ;PLoS Genet.. 2011-06-01
• TRIM16 acts as a tumour suppressor by inhibitory effects on cytoplasmic vimentin and nuclear E2F1 in neuroblastoma cells.
  Marshall GM, Bell JL, Koach J, Tan O, Kim P, Malyukova A, Thomas W, Sekyere EO, Liu T, Cunningham AM, Tobias V, Norris MD, Haber M, Kavallaris M, Cheung BB> ;Oncogene. 2010-11-18
• Absence of SHIP-1 results in constitutive phosphorylation of tank-binding kinase 1 and enhanced TLR3-dependent IFN-beta production.
  Gabhann JN, Higgs R, Brennan K, Thomas W, Damen JE, Ben Larbi N, Krystal G, Jefferies CA> ;J. Immunol.. 2010-03-01
• The estrogen-responsive B box protein (EBBP) restores retinoid sensitivity in retinoid-resistant cancer cells via effects on histone acetylation.
  Raif A, Marshall GM, Bell JL, Koach J, Tan O, D'andreti C, Thomas W, Sekyere E, Norris M, Haber M, Kavallaris M, Cheung BB> ;Cancer Lett.. 2009-05-08
• ATP7A is a novel target of retinoic acid receptor beta2 in neuroblastoma cells.
  Bohlken A, Cheung BB, Bell JL, Koach J, Smith S, Sekyere E, Thomas W, Norris M, Haber M, Lovejoy DB, Richardson DR, Marshall GM> ;Br. J. Cancer. 2009-01-13
• ODC1 is a critical determinant of MYCN oncogenesis and a therapeutic target in neuroblastoma.
  Hogarty MD, Norris MD, Davis K, Liu X, Evageliou NF, Hayes CS, Pawel B, Guo R, Zhao H, Sekyere E, Keating J, Thomas W, Cheng NC, Murray J, Smith J, Sutton R, Venn N, L...> ;Cancer Res.. 2008-12-01
• Integrin-like allosteric properties of the catch bond-forming FimH adhesin of Escherichia coli.
  Tchesnokova V, Aprikian P, Yakovenko O, Larock C, Kidd B, Vogel V, Thomas W, Sokurenko E> ;J. Biol. Chem.. 2008-03-21
• The DNase of gammaherpesviruses impairs recognition by virus-specific CD8+ T cells through an additional host shutoff function.
  Zuo J, Thomas W, van Leeuwen D, Middeldorp JM, Wiertz EJHJ, Ressing ME, Rowe M> ;J. Virol.. 2008-03-01
• Interdomain interaction in the FimH adhesin of Escherichia coli regulates the affinity to mannose.
  Aprikian P, Tchesnokova V, Kidd B, Yakovenko O, Yarov-Yarovoy V, Trinchina E, Vogel V, Thomas W, Sokurenko E> ;J. Biol. Chem.. 2007-08-10
• Recombinant protein-based assays for detection of antibodies to severe acute respiratory syndrome coronavirus spike and nucleocapsid proteins.
  Haynes LM, Miao C, Harcourt JL, Montgomery JM, Le MQ, Dryga SA, Kamrud KI, Rivers B, Babcock GJ, Oliver JB, Comer JA, Reynolds M, Uyeki TM, Bausch D, Ksiazek T, Thomas...> ;Clin. Vaccine Immunol.. 2007-03-01
• The estrogen-responsive B box protein is a novel regulator of the retinoid signal.
  Cheung BB, Bell J, Raif A, Bohlken A, Yan J, Roediger B, Poljak A, Smith S, Lee M, Thomas WD, Kavallaris M, Norris M, Haber M, Liu H, Zajchowski D, Marshall GM> ;J. Biol. Chem.. 2006-06-30
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