WadieFBahouMD

PubMed

• Metabolic Functions of Biliverdin IXβ Reductase in Redox-Regulated Hematopoietic Cell Fate.
  Wadie F Bahou, Natalia Marchenko, Natasha M Nesbitt> ;Antioxidants. 2023 May 7
• 4 citations
  Age-restricted functional and developmental differences of neonatal platelets.
  Zhaoyan Liu, Cecilia Avila, Lisa E Malone, Dmitri V Gnatenko, Jawaad Sheriff, Wei Zhu, Wadie F Bahou> ;Journal of Thrombosis and Haemostasis. 2022 Nov 1
• 2 citations
  Cytokine pathway variants modulate platelet production: IFNA16 is a thrombocytosis susceptibility locus in humans.
  Dmitri V Gnatenko, Zhaoyan Liu, Patrick Hearing, Sook-Young Sohn, Yetao Hu, Anna Falanga, Song Wu, Lisa E Malone, Wei Zhu, Wadie F Bahou> ;Blood Advances. 2022 Aug 23
• 2 citations
  Genetic pathways regulating hematopoietic lineage speciation: Factorial latent variable model analysis of single cell transcriptome.
  Zhaoyan Liu, Wei Zhu, Dmitri V. Gnatenko, Natasha M. Nesbitt, Wadie F. Bahou> ;Data in Brief. 2021 Apr 22
• 8 citations
  Divergent erythroid megakaryocyte fates in Blvrb-deficient mice establish non-overlapping cytoprotective functions during stress hematopoiesis.
  Natasha M. Nesbitt, Lisa E. Malone, Zhaoyan Liu, Alexander Jares, Dmitri V. Gnatenko, Yupo Ma, Wei Zhu, Wadie F. Bahou> ;Free Radical Biology & Medicine. 2021 Feb 20
• 25 citations
  Novel manifestations of immune dysregulation and granule defects in gray platelet syndrome
  Matthew C Sims, Louisa Mayer, Janine Collins, Tadbir K. Bariana, Karyn Megy, Cécile Lavenu-Bombled, Denis Seyres, Laxmikanth Kollipara, Frances Burden, Daniel Greene, ...> ;Blood. 2020 Oct 22
• 2 citations
  Shear-Induced Platelet Activation is Sensitive to Age and Calcium Availability: A Comparison of Adult and Cord Blood
  Jawaad Sheriff, Lisa E. Malone, Cecilia Avila, Amanda Zigomalas, Danny Bluestein, Wadie F. Bahou> ;Cellular and Molecular Bioengineering. 2020 Jun 22
• 5 citations
  Biochemical characterization of biliverdins IXβ/δ generated by a selective heme oxygenase.
  Beibei Zhang, Natasha M. Nesbitt, Pedro Pereira, Wadie F. Bahou> ;The Biochemical Journal. 2020 Feb 14
• 13 citations
  Assessment of neonatal, cord, and adult platelet granule trafficking and secretion.
  Anh T. P. Ngo, Jawaad Sheriff, Anne D. Rocheleau, Matthew Bucher, Kendra R. Jones, Anna Liisa I. Sepp, Lisa E. Malone, Amanda Zigomalas, Alina Maloyan, Wadie F. Bahou,...> ;Platelets. 2020 Jan 2
• 7 citations
  Heme degradation enzyme biliverdin IXβ reductase is required for stem cell glutamine metabolism.
  Zongdong Li, Natasha M. Nesbitt, Lisa E. Malone, Dimitri V. Gnatenko, Song Wu, Daifeng Wang, Wei Zhu, Geoffrey D. Girnun, Wadie F. Bahou> ;The Biochemical Journal. 2018 Mar 30
• 5 citations
  In silico and crystallographic studies identify key structural features of biliverdin IXβ reductase inhibitors having nanomolar potency.
  Natasha M. Nesbitt, Xiliang Zheng, Zongdong Li, José A. Manso, Wan-Yi Yen, Lisa E. Malone, Jorge Ripoll-Rozada, Pedro Pereira, Timothy J. Mantle, Jin Wang, Wadie F. Bahou> ;The Journal of Biological Chemistry. 2018 Feb 27
• 7 citations
  Integrated micro/messenger RNA regulatory networks in essential thrombocytosis.
  Lu Zhao, Song Wu, Erya Huang, Dimitri V. Gnatenko, Wadie F. Bahou, Wei Zhu> ;Plos One. 2018 Feb 8
• 12 citations
  Enzymatic Activity and Thermodynamic Stability of Biliverdin IXβ Reductase Are Maintained by an Active Site Serine.
  Wen-Ting Chu, Natasha M. Nesbitt, Dmitri V. Gnatenko, Zongdong Li, Beibei Zhang, Markus A. Seeliger, Seamus Browne, Timothy J. Mantle, Wadie F. Bahou, Jin Wang> ;Chemistry. 2017 Feb 3
• 26 citations
  BLVRB redox mutation defines heme degradation in a metabolic pathway of enhanced thrombopoiesis in humans
  Song Wu, Zongdong Li, Dmitri V. Gnatenko, Beibei Zhang, Lu Zhao, Lisa E. Malone, Nedialka G. Markova, Timothy J. Mantle, Natasha M. Nesbitt, Wadie F. Bahou> ;Blood. 2016 Aug 4
• 100 citations
  Unraveling the Role of KIAA1199, a Novel Endoplasmic Reticulum Protein, in Cancer Cell Migration
  Nikki A. Evensen, Cem Kuscu, Hoang-Lan Nguyen, Kevin Zarrabi, Antoine Dufour, Pournima Kadam, You-jun Hu, Ashleigh Pulkoski-Gross, Wadie F. Bahou, Stanley Zucker, Jian...> ;Journal of the National Cancer Institute. 2013 Sep 18
• 7 citations
  Expression, function and cooperating partners of protease-activated receptor type 3 in vascular endothelial cells and B lymphocytes studied with specific monoclonal an...
  Olena Kalashnyk, Yuliya I. Petrova, Olena Lykhmus, L. Mikhalovska, Sergiy Mikhalovsky, Anastasiya I. Zhukova, Dmitri V. Gnatenko, Wadie F. Bahou, Serhiy Komisarenko, M...> ;Molecular Immunology. 2013 Jul 1
• 3 citations
  Genetic dissection of platelet function in health and disease using systems biology.
  Wadie F. Bahou> ;Hematology/oncology Clinics of North America. 2013 Jun 1
• Platelet genetic biomarker quantification: Comparison of fluorescent microspheres and PCR platforms
  Erya Huang, Wei Zhu, Anil Dhundale, Wadie F. Bahou, Dmitri V. Gnatenko> ;Thrombosis and Haemostasis. 2012 Dec 6
• 25 citations
  Systematic analysis of microRNA fingerprints in thrombocythemic platelets using integrated platforms
  Xiao Xu, Dmitri V. Gnatenko, Jingfang Ju, Ian S. Hitchcock, Dwight W. Martin, Wei Zhu, Wadie F. Bahou> ;Blood. 2012 Oct 25
• 6 citations
  Platelet systems biology using integrated genetic and proteomic platforms
  Wadie F. Bahou> ;Thrombosis Research. 2012 Apr 1
• 49 citations
  ERK1/2 activation in heart is controlled by melusin, focal adhesion kinase and the scaffold protein IQGAP1.
  Mauro Sbroggiò, Alessandro Bertero, Silvia Velasco, Federica Fusella, Emanuele De Blasio, Wadie F. Bahou, Lorenzo Silengo, Emilia Turco, Mara Brancaccio, Guido Tarone> ;Journal of Cell Science. 2011 Oct 15
• 14 citations
  Ablation of Iqgap2 protects from diet-induced hepatic steatosis due to impaired fatty acid uptake
  Carmine S. Chiariello, Joseph F. LaComb, Wadie F. Bahou, Valentina A. Schmidt> ;Regulatory Peptides. 2012 Jan 10
• 15 citations
  Computationally designed adeno-associated virus (AAV) Rep 78 is efficiently maintained within an adenovirus vector
  Varsha Sitaraman, Patrick Hearing, Charles B. Ward, Dmitri V. Gnatenko, Eckard Wimmer, Steffen Mueller, Steven Skiena, Wadie F. Bahou> ;Proceedings of the National Academy of Sciences of the United States of America. 2011 Aug 23
• 68 citations
  IQGAP1 regulates ERK1/2 and AKT signalling in the heart and sustains functional remodelling upon pressure overload
  Mauro Sbroggiò, Daniela Carnevale, Alessandro Bertero, Giuseppe Cifelli, Emanuele De Blasio, Giada Mascio, Emilio Hirsch, Wadie F. Bahou, Emilia Turco, Lorenzo Silengo...> ;Cardiovascular Research. 2011 Aug 1
• 11 citations
  Furin Functions as a Nonproteolytic Chaperone for Matrix Metalloproteinase-28: MMP-28 Propeptide Sequence Requirement.
  Maria Pavlaki, Stanley Zucker, Antoine Dufour, Nikki Calabrese, Wadie F. Bahou, Jian Cao> ;Biochemistry Research International. 2011 Jan 1
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