WaldemarACarloMD

Neonat/Perinatology • Birmingham, AL

Professor, Pediatrics, University of Alabama School of Medicine

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Office
1700 6th Avenue S
WIC 9380 UAB
Birmingham, AL 35249
Phone+1 205-934-4680

Fax+1 205-934-3100
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Summary

Director, Division of Neonatology

Education & Training

Case Western Reserve Univ/Univ Hosps Cleveland Med Ctr/Rainbow Babies and Childrens HospitalFellowship, Neonatal-Perinatal Medicine, 1980 - 1982
University of Puerto RicoResidency, Pediatrics, 1977 - 1980
University of Puerto Rico School of MedicineClass of 1977

Certifications & Licensure

AL State Medical License 1991 - 2024
OH State Medical License 1981 - 1998
American Board of Pediatrics Pediatrics
American Board of Pediatrics Neonatal-Perinatal Medicine

Clinical Trials

Whole-Body Cooling for Birth Asphyxia in Term Infants Start of enrollment: 1999 Oct 01
Completed
Phase 3
Early Inhaled Nitric Oxide for Respiratory Failure in Newborns Start of enrollment: 1998 Aug 01
Terminated
Phase 3
Early Surfactant to Reduce Use of Mechanical Breathing in Low Birth Weight Infants Start of enrollment: 2000 May 01
Terminated
Phase 3
Glutamine Supplementation to Prevent Death or Infection in Extremely Premature Infants Start of enrollment: 1999 Jul 01
Completed
Phase 3
Minimal Breathing Support and Early Steroids to Prevent Chronic Lung Disease in Extremely Premature Infants (SAVE) Start of enrollment: 1998 Feb 01
Terminated
Phase 3
Follow-up Visit of High Risk Infants Start of enrollment: 1993 Jan 01
Recruiting
Trial of Indomethacin Prophylaxis in Preterm Infants (TIPP) Start of enrollment: 1993 Nov 01
Completed
Phase 3
Inhaled Nitric Oxide for Preterm Infants With Severe Respiratory Failure Start of enrollment: 2001 Jan 01
Terminated
Phase 3
Generic Database of Very Low Birth Weight Infants Start of enrollment: 1987 Jan 01
Recruiting
Benchmarking Initiative to Reduce Bronchopulmonary Dysplasia Start of enrollment: 2001 Mar 01
Completed
Not Applicable
Neonatal Resuscitation in Zambia Start of enrollment: 2004 Oct 01
Completed
Phase 3
Early Diagnosis of Candidiasis in Premature Infants Start of enrollment: 2004 Mar 01
Completed
Trial of Aggressive Versus Conservative Phototherapy in Infants <1,000 Grams Birth Weight Start of enrollment: 2002 Sep 01
Completed
Phase 3
Surfactant Positive Airway Pressure and Pulse Oximetry Trial Start of enrollment: 2005 Feb 01
Completed
Phase 3
Immunogenicity of PCV-7 Vaccine in VLBW Infants Start of enrollment: 2004 Jul 01
Completed
Single-Dose Intravenous Inositol Pharmacokinetics in Preterm Infants Start of enrollment: 2006 Jun 01
Completed
Phase 2
Inhaled PGE1 in Neonatal Hypoxemic Respiratory Failure Start of enrollment: 2008 May 01
Withdrawn
Phase 2
Late Hypothermia for Hypoxic-Ischemic Encephalopathy Start of enrollment: 2008 Apr 01
Completed
Not Applicable
Inhaled Nitric Oxide by Oxygen Hood in Neonates Start of enrollment: 1999 Mar 01
Completed
Phase 4
Early-Onset Sepsis Surveillance Study Start of enrollment: 2006 Feb 01
Completed
Early Blood Pressure Management in Extremely Premature Infants Start of enrollment: 2009 Jul 01
Completed
Phase 1
Hypotension in Neonates Start of enrollment: 2009 Apr 01
Completed
Laparotomy vs. Drainage for Infants With Necrotizing Enterocolitis Start of enrollment: 2010 Jan 01
Completed
Not Applicable
Multi-dose Pharmacokinetics and Dose Ranging of Inositol in Premature Infants (INS-2) Start of enrollment: 2010 Jan 01
Completed
Phase 2
Inflammatory Cytokines Associated With Perinatal Brain Injury Start of enrollment: 1999 Jul 01
Completed
Maternal Newborn Health Registry Start of enrollment: 2008 May 01
Recruiting
Optimizing (Longer, Deeper) Cooling for Neonatal Hypoxic-Ischemic Encephalopathy(HIE) Start of enrollment: 2010 Sep 01
Terminated
Not Applicable
Vitamin E for Extremely Preterm Infants Start of enrollment: 2010 Oct 01
Completed
Phase 1
Oronasopharyngeal Suction Versus Simple Nose and Mouth Wiping in Term Newborns Start of enrollment: 2010 Nov 01
Completed
Not Applicable
In Utero Magnesium Sulfate Exposure: Effects on Extremely-Low-Birth-Weight Infants Start of enrollment: 1996 Jul 01
Completed
Delayed Cord Clamping in VLBW Infants Start of enrollment: 2000 Jun 01
Completed
Phase 1, Phase 2
Observational Study of Surgical Treatment of Necrotizing Enterocolotis Start of enrollment: 2001 Mar 01
Completed
Delivery Room CPAP in Extremely Low Birth Weight Infants Start of enrollment: 2002 Jul 01
Completed
Phase 1, Phase 2
Physiologic Definition of Bronchopulmonary Dysplasia Start of enrollment: 2005 May 01
Completed
Feasibility of Mid-frequency Ventilation in Newborns With RDS: Randomized Crossover Pilot Trial Start of enrollment: 2011 Oct 01
Completed
Phase 1, Phase 2
Hydrocortisone for BPD Start of enrollment: 2011 Aug 11
Active, not recruiting
Phase 3
Evaluate the Use of Plastic Bags in Preventing and Treating Hypothermia in Neonates Start of enrollment: 2011 Aug 01
Completed
Phase 4
Re-feeding Gastric Residuals in Preterm Infants Start of enrollment: 2011 Aug 01
Completed
Not Applicable
Inhaled Prostaglandin E1 (IPGE1) for Hypoxemic Respiratory Failure (NHRF) Start of enrollment: 2011 Nov 01
Terminated
Phase 2
Donor Milk vs. Formula in Extremely Low Birth Weight (ELBW) Infants Start of enrollment: 2012 Aug 01
Completed
Phase 3
Evaluation of Use of Plastic Bags to Prevent Neonatal Hypothermia-Part I Start of enrollment: 2012 Jun 01
Active, not recruiting
Not Applicable
Evaluation of Use of Plastic Bags to Prevent Neonatal Hypothermia-Part II Start of enrollment: 2013 Feb 01
Withdrawn
Not Applicable
Evaluation of Use of Plastic Bags to Prevent Neonatal Hypothermia-Part III Start of enrollment: 2012 Jun 01
Withdrawn
Not Applicable
Evaluation of Use of Plastic Bags to Prevent Neonatal Hypothermia-Part IV Start of enrollment: 2012 Jun 01
Completed
Phase 4
Evaluation of Use of Plastic Bags to Prevent Neonatal Hypothermia-Part V Start of enrollment: 2012 Jun 01
Completed
Phase 4
Transfusion of Prematures Trial Start of enrollment: 2012 Dec 01
Active, not recruiting
Phase 3
Generic Database of Moderate Preterm Infants Start of enrollment: 2012 Mar 01
Completed
Preemie Hypothermia for Neonatal Encephalopathy Start of enrollment: 2015 May 01
Completed
Not Applicable
Hydrocortisone for Term Hypotension Start of enrollment: 2014 Jun 19
Completed
Phase 3
Inositol to Reduce Retinopathy of Prematurity Start of enrollment: 2014 Apr 17
Terminated
Phase 3
Kangaroo Mother Care to Prevent Hypothermia in Preterm Infants Start of enrollment: 2014 Jun 01
Completed
Not Applicable
Kangaroo Mother Care to Prevent Hypothermia in Term Infants Start of enrollment: 2014 Aug 01
Completed
Not Applicable
Early-Onset Sepsis an NICHD/CDC Surveillance Study Start of enrollment: 2015 Apr 01
Completed
Kangaroo Mother Care With Plastic Bag (Trials 2A & 2B) Start of enrollment: 2017 May 19
Completed
Not Applicable
Kangaroo Mother Care With Plastic Bag (Trials 1A & 1B) Start of enrollment: 2024 Nov 19
Withdrawn
Not Applicable
Mid and Standard Frequency Ventilation in Infants With Respiratory Distress Syndrome Start of enrollment: 2017 Aug 02
Active, not recruiting
Phase 2, Phase 3
Moderately Preterm Infants With Caffeine at Home for Apnea (MoCHA) Trial Start of enrollment: 2019 Feb 27
Active, not recruiting
Phase 3
Cycled Phototherapy Start of enrollment: 2020 Jul 15
Recruiting
Not Applicable
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Publications & Presentations

PubMed

Social Determinants of Health and Redirection of Care for Infants Born Extremely Preterm.
Jane E Brumbaugh, Carla M Bann, Edward F Bell, Colm P Travers, Betty R Vohr, Elisabeth C McGowan, Heidi M Harmon, Waldemar A Carlo, Susan R Hintz, Andrea F Duncan> ;JAMA Pediatrics. 2024 Mar 11
Social distancing and extremely preterm births in the initial COVID-19 pandemic period.
Carper, B., Rysavy, M., Bell, E., Das, A., Patel, R., D'Angio, C., Cotten, C., Merhar, S., Wyckoff, M., Sánchez, P., , Shukla, V., Ambalavanan, N., Watterberg, K., Kum...> ;Journal of Perinatology. 2024 Feb 22
1 citations
Neurodevelopmental Outcomes of Extremely Preterm Infants Fed Donor Milk or Preterm Infant Formula: A Randomized Clinical Trial.
Tarah T Colaizy, Brenda B Poindexter, Scott A McDonald, Edward F Bell, Waldemar A Carlo, Susan J Carlson, Sara B DeMauro, Kathleen A Kennedy, Leif D Nelin, Pablo J Sán...> ;JAMA. 2024 Feb 20
Predicting peripartum infection in laboring patients at high risk in Cameroon, Africa.
Cozzi, G., Ye, Y., Mbah, R., Mbunwe, D., Pekwarake, S., Yui Bunwi, E., Fondzeyuf, A., Ngong, M., Dionne, J., Harper, L., Jauk, V., Carlo, W., Halle-Ekane, G., Tih, P.,...> ;European Journal of Obstetrics, Gynecology, and Reproductive Biology. 2024 Feb 1
1 citations
Health Insurance and Differences in Infant Mortality Rates in the US.
Desalyn L Johnson, Waldemar A Carlo, A K M Fazlur Rahman, Rachel Tindal, Mykaela J Watt, Colm P Travers, Trulove, G., Sarah G Trulove> ;JAMA Network Open. 2023 Oct 2
Can the date of last menstrual period be trusted in the first trimester? Comparisons of gestational age measures from a prospective cohort study in six low-income to m...
Archana Patel, Carla M Bann, Vanessa R Thorsten, Sowmya R Rao, Adrien Lokangaka, Antoinette Tshefu Kitoto, Melissa Bauserman, Lester Figueroa, Nancy F Krebs, Fabian Es...> ;BMJ Open. 2023 Sep 20
1 citations
Tissue Oxygenation Changes After Transfusion and Outcomes in Preterm Infants: A Secondary Near-Infrared Spectroscopy Study of the Transfusion of Prematures Randomized ...
Brion, L. P., Chock, V., Kirpalani, H., Bell, E., Tan, S., Hintz, S., Ball, M., Smith, E., Das, A., Loggins, Y., Sood, B., Chalak, L., Wyckoff, M., Kicklighter, S., Ke...> ;JAMA Network Open. 2023 Sep 5
2 citations
Early Human Milk Fortification in Infants Born Extremely Preterm: A Randomized Trial.
Ariel A Salas, Emily Gunawan, Kelly Nguyen, Audrey Reeves, Victoria Argent, Amber Finck, Waldemar A Carlo> ;Pediatrics. 2023 Sep 1
Prevention of maternal and neonatal death/infections with a single oral dose of azithromycin in women in labour in low-income and middle-income countries (A-PLUS): a s...
Jennifer Hemingway-Foday, Alan Tita, Elwyn Chomba, Musaku Mwenechanya, Trecious Mweemba, Tracy Nolen, Adrien Lokangaka, Antoinette Tshefu Kitoto, Gustave Lomendje, Pat...> ;BMJ Open. 2023 Aug 30
Building a predictive model of low birth weight in low- and middle-income countries: a prospective cohort study.
Jackie K Patterson, Vanessa R Thorsten, Barry Eggleston, Tracy Nolen, Adrien Lokangaka, Antoinette Tshefu, Shivaprasad S Goudar, Richard J Derman, Elwyn Chomba, Waldem...> ;BMC Pregnancy and Childbirth. 2023 Aug 22
Trends over time in the knowledge, attitude and practices of pregnant women related to COVID-19: A cross-sectional survey from seven low- and middle-income countries.
Saleem Jessani, Sarah Saleem, Elizabeth Fogleman, Sk Masum Billah, Rashidul Haque, Lester Figueroa, Adrien Lokangaka, Antoinette Tshefu, Shivaprasad S Goudar, Avinash ...> ;BJOG. 2023 Nov 1
The impact of risk factors on aspirin's efficacy for the prevention of preterm birth.
Emily E Nuss, Matthew K Hoffman, Shivaprasad S Goudar, Avinash Kavi, Mrityunjay Metgud, Manjunath Somannavar, Jean Okitawutshu, Adrien Lokangaka, Antoinette Tshefu, Me...> ;American Journal of Obstetrics & Gynecology MFM. 2023 Oct 1
1 citations
The Global Network COVID-19 studies: a review.
Seemab Naqvi, Sarah Saleem, Sk Masum Billah, Janet Moore, Musaku Mwenechanya, Waldemar A Carlo, Fabian Esamai, Sherri Bucher, Richard J Derman, Shivaprasad S Goudar, M...> ;BJOG. 2023 Nov 1
1 citations
Preterm Prenatal Education-A Novel Approach.
Amelia Q Schuyler, Waldemar A Carlo> ;JAMA Pediatrics. 2023 Jul 31
2 citations
COVID-19 symptoms and antibody positivity among unvaccinated pregnant women: An observational study in seven countries from the Global Network.
Avinash Kavi, Shivaprasad S Goudar, Manjunath S Somannavar, Janet L Moore, Richard J Derman, Sarah Saleem, Seemab Naqvi, Sk Masum Billah, Rashidul Haque, Lester Figuer...> ;BJOG. 2023 Nov 1
A few breaths at birth; a lifetime of health.
Waldemar A Carlo, Vivek V Shukla> ;Jornal De Pediatria. 2023 Jul 20
1 citations
Aspirin delays the onset of hypertensive disorders of pregnancy among nulliparous pregnant women: A secondary analysis of the ASPIRIN trial.
Avinash Kavi, Matthew K Hoffman, Manjunath S Somannavar, Mrityunjay C Metgud, Shivaprasad S Goudar, Janet Moore, Eleanor Nielsen, Norman Goco, Elizabeth M McClure, Adr...> ;BJOG. 2023 Nov 1
Diagnostic accuracy of ASQ for screening of neurodevelopmental delays in low resource countries.
Albert Manasyan, Ariel A Salas, Tracy Nolen, Elwyn Chomba, Manolo Mazariegos, Antoinette Tshefu Kitoto, Sarah Saleem, Farnaz Naqvi, K Michael Hambidge, Norman Goco, El...> ;BMJ Open. 2023 May 23
Heterogeneity of Treatment Effects of Hydrocortisone by Risk of Bronchopulmonary Dysplasia or Death Among Extremely Preterm Infants in the National Institute of Child ...
Samuel J Gentle, Matthew A Rysavy, Lei Li, Matthew M Laughon, Ravi M Patel, Erik A Jensen, Susan Hintz, Namasivayam Ambalavanan, Waldemar A Carlo, Kristi Watterberg, ,...> ;JAMA Network Open. 2023 May 1
1 citations
Late permissive hypercapnia and respiratory stability among very preterm infants: a pilot randomised trial.
Colm P Travers, Waldemar A Carlo, Arie Nakhmani, Deborah Laney, Rouba A Chahine, Immaculada Aban, Namasivayam Ambalavanan> ;Archives of Disease in Childhood. Fetal and Neonatal Edition. 2023 Sep 1
1 citations
Trends in fetal and neonatal outcomes during the COVID-19 pandemic in Alabama.
Vivek V Shukla, A K M Fazlur Rahman, Xuejun Shen, Allison Black, Nitin Arora, C Vivek Lal, Edward F Bell, Arie Nakhmani, Chengcui Zhang, Namasivayam Ambalavanan, Walde...> ;Pediatric Research. 2023 Aug 1
3 citations
Cost-effectiveness of low-dose aspirin for the prevention of preterm birth: a prospective study of the Global Network for Women's and Children's Health Research.
Jackie K Patterson, Simon Neuwahl, Norman Goco, Janet Moore, Shivaprasad S Goudar, Richard J Derman, Matthew Hoffman, Mrityunjay Metgud, Manjunath Somannavar, Avinash ...> ;The Lancet. Global Health. 2023 Mar 1
7 citations
Azithromycin to Prevent Sepsis or Death in Women Planning a Vaginal Birth.
Alan T N Tita, Waldemar A Carlo, Elizabeth M McClure, Musaku Mwenechanya, Elwyn Chomba, Jennifer J Hemingway-Foday, Avinash Kavi, Mrityunjay C Metgud, Shivaprasad S Go...> ;The New England Journal of Medicine. 2023 Mar 30
3 citations
Association of Active Postnatal Care With Infant Survival Among Periviable Infants in the US.
Emani R Silva, Vivek V Shukla, Waldemar A Carlo, Colm P Travers, Rachel Tindal> ;JAMA Network Open. 2023 Jan 3
4 citations
COVID-19 antibody positivity over time and pregnancy outcomes in seven low-and-middle-income countries: A prospective, observational study of the Global Network for Wo...
Robert L Goldenberg, Sarah Saleem, Sk Masum Billah, Jean Kim, Janet L Moore, Najia Karim Ghanchi, Rashidul Haque, Lester Figueroa, Alejandra Ayala, Adrien Lokangaka, A...> ;BJOG. 2023 Mar 1
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Journal Articles

Higher or Lower Hemoglobin Transfusion Thresholds for Preterm Infants
Haresh Kirpalani, Susan R Hintz, Betty R Vohr, Waldemar A Carlo, Kathleen A Kennedy, Robin K Ohls, Kurt Schibler, John A Widness, John AF Zupancic, Myra H Wyckoff, Wil..., The New England Journal of Medicine
Predictive Modeling for Perinatal Mortality in Resource-Limited Settings
Namasivayam Ambalavanan, Carl Bose, Melissa Bauserman, Edward A Liechty, Waldemar A Carlo, JAMA Network Open
Racial/Ethnic Disparities Among Extremely Preterm Infants in the United States from 2002 to 2016
Colm P Travers, Waldemar A Carlo, Namasivayam Ambalavanan, Barbara J Stoll, Myra H Wyckoff, Seetha Shankaran, Sara B Demauro, Michele C Walsh, Scott A Lorch, Margarita..., JAMA Network Open
Early-Onset Neonatal Sepsis 2015 to 2017, the Rise of Escherichia Coli, and the Need for Novel Prevention Strategies
Barbara J Stoll, Waldemar A Carlo, Myra H Wyckoff, Bradley A Yoder, Kristi L Watterberg, Michele C Walsh, Gregory M Sokol, JAMA Pediatrics
Association Between Oxygen Saturation Targeting and Death or Disability in Extremely Preterm Infants in the Neonatal Oxygenation Prospective Meta-Analysis Collaboration
Barbara Schmidt, Waldemar A Carlo, JAMA
A Comparison of 3 Vitamin D Dosing Regimens in Extremely Preterm Infants: A Randomized Controlled Trial
Waldemar A Carlo, Prem Fort, Namasivayam Ambalavanan, Ariel A Salas, The Journal of Pediatrics
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Authored Content

Racial/Ethnic Disparities Among Extremely Preterm Infants in the United States from 2002 to 2016June 2020
Early-Onset Neonatal Sepsis 2015 to 2017, the Rise of Escherichia Coli, and the Need for Novel Prevention StrategiesMay 2020

Press Mentions

Couple Holds Wedding Ceremony in Hospital NICU Next to Their Premature DaughterApril 16th, 2018
This Couple Got Married in the NICU so Their Preemie Could Be There, and OMG, Our HeartsApril 16th, 2018

Grant Support

Cooperative Multicenter Neonatal Research Network - UABEunice Kennedy Shriver National Institute Of Child Health &Human Development2011–2012
COMMUNITY-BASED Interventions To Reduce Mortality From Neonatal InfectionEunice Kennedy Shriver National Institute Of Child Health &Human Development2008–2012
Nichd Cooperative Multicenter Neonatal Research NetworkEunice Kennedy Shriver National Institute Of Child Health &Human Development2006–2010
Brain Research To Ameliorate Impaired Neurodevelopment-Home-Based InterventionEunice Kennedy Shriver National Institute Of Child Health &Human Development2006–2010
Neonatal Resuscitation In Developing CountriesEunice Kennedy Shriver National Institute Of Child Health &Human Development2003–2007
Brain Planning Grant For The Developing WorldFogarty International Center2003–2005
Multicenter Network Of Neonatal Intensive Care UnitsEunice Kennedy Shriver National Institute Of Child Health &Human Development1996–2005
Respiratory Control Of The Alae Nasi In Preterm InfantsNational Heart, Lung, And Blood Institute1985