WarrenDavidShlomchikMD

PubMed

• T cell exhaustion and a failure in antigen presentation drive resistance to the graft-versus-leukemia effect.
  Zhou, M., Sacirbegovic, F., Zhao, K., Rosenberger, S., Shlomchik, W. D.> ;Nature communications. 2020 Aug 26
• Cross-dressed dendritic cells sustain effector T cell responses in islet and kidney allografts.
  Hughes, A. D., Zhao, D., Dai, H., Abou-Daya, K. I., Tieu, R., Rammal, R., Williams, A. L., Landsittel, D. P., Shlomchik, W. D., Morelli, A. E., Oberbarnscheidt, M. H.,...> ;The Journal of clinical investigation. 2019 Nov 26
• In vivo dynamics of T cells and their interactions with dendritic cells in mouse cutaneous graft-versus-host disease
  Sarah Morin-Zorman, Christian A. Wysocki, Jieqing Zhu, Hongmei Li, Sylvain Zorman, Catherine Matte-Martone, Edwina P. Kisanga, Jennifer M. McNiff, Dhanpat Jain, David ...> ;Blood Advances. 2019 Jul 23
• Long-term follow-up of a single institution pilot study of sirolimus, tacrolimus, and short course methotrexate for graft versus host disease prophylaxis in mismatched...
  Tae Kon Kim, Michelle DeVeaux, Maximilian Stahl, Sarah Perreault, Iris Isufi, Dennis L. Cooper, Francine M. Foss, Warren D. Shlomchik, Daniel Zelterman, Amer M. Zeidan...> ;Annals of Hematology. 2019 Jan 1
• Bim regulates the survival and suppressive capability of CD8⁺ FOXP3⁺ regulatory T cells during murine GVHD.
  Agle, K., Vincent, B. G., Piper, C., Belle, L., Zhou, V., Shlomchik, W. D., Serody, J. S., Drobyski, W. R.> ;Blood. 2018 May 18
• PD-L1 Prevents the Development of Autoimmune Heart Disease in Graft-versus-Host Disease.
  Juchem, K. W., Sacirbegovic, F., Zhang, C., Sharpe, A. H., Russell, K. S., McNiff, J. M., Demetris, A. J., Shlomchik, M. J., Shlomchik, W. D.> ;Journal of immunology (Baltimore, Md. : 1950). 2017 Dec 8
• Differential requirements for myeloid leukemia IFN-γ conditioning determine graft-versus-leukemia resistance and sensitivity.
  Matte-Martone, C., Liu, J., Zhou, M., Chikina, M., Green, D. R., Harty, J. T., Shlomchik, W. D.> ;The Journal of clinical investigation. 2017 Jun 13
• Type 2 innate lymphoid cells treat and prevent acute gastrointestinal graft-versus-host disease
  Danny W. Bruce, Heather E. Stefanski, Benjamin G. Vincent, Trisha A. Dant, Shannon Reisdorf, Hemamalini Bommiasamy, David A. Serody, Justin E. Wilson, Karen P. McKinno...> ;Journal of Clinical Investigation. 2017 May 1
• 10 citations
  Outcomes of acute leukemia patients transplanted with naive T cell-depleted stem cell grafts.
  Bleakley, M., Heimfeld, S., Loeb, K. R., Jones, L. A., Chaney, C., Seropian, S., Gooley, T. A., Sommermeyer, F., Riddell, S. R., Shlomchik, W. D.> ;The Journal of clinical investigation. 2015 Jun 9
• 7 citations
  CD45 ligation expands Tregs by promoting interactions with DCs.
  Camirand, G., Wang, Y., Lu, Y., Wan, Y. Y., Lin, Y., Deng, S., Guz, G., Perkins, D. L., Finn, P. W., Farber, D. L., Flavell, R. A., Shlomchik, W. D., Lakkis, F. G., Ru...> ;The Journal of clinical investigation. 2014 Sep 10
• Cognate antigen directs CD8+ T cell migration to vascularized transplants
  Jeffrey M. Walch, Qiang Zeng, Qi Li, Martin H. Oberbarnscheidt, Rosemary A. Hoffman, Amanda L. Williams, David M. Rothstein, Warren D. Shlomchik, Jiyun V. Kim, Geoffre...> ;Journal of Clinical Investigation. 2013 Jun 3
• Allograft outcomes in outbred mice.
  Reichenbach, D. K.,Li, Q.,Hoffman, R. A.,Williams, A. L.,Shlomchik, W. D.,Rothstein, D. M.,Demetris, A. J.,Lakkis, F. G.> ;Am. J. Transplant.. 2013 Mar
• 8 citations
  Profound depletion of host conventional dendritic cells, plasmacytoid dendritic cells, and B cells does not prevent graft-versus-host disease induction.
  Li, H., Demetris, A. J., McNiff, J. M., Matte-Martone, C., Tan, H. S., Rothstein, D. M., Lakkis, F. G., Shlomchik, W. D.> ;Journal of immunology (Baltimore, Md. : 1950). 2012 Mar 17
• 4 citations
  Innate immunity alone is not sufficient for chronic rejection but predisposes healed allografts to T cell-mediated pathology.
  Zecher, D., Li, Q., Williams, A. L., Walters, J. T., Baddoura, F. K., Chalasani, G., Rothstein, D. M., Shlomchik, W. D., Demetris, A. J., Lakkis, F. G.> ;Transplant immunology. 2012 Jan 10
• Graft-versus-Leukemia (GVL) against Mouse Blast-Crisis Chronic Myelogenous Leukemia (BC-CML) and Chronic-Phase Chronic Myelogenous Leukemia (CP-CML): Shared Mechanisms...
  Catherine Matte-Martone, Srividhya Venkatesan, Hung Sheng Tan, Ioanna Athanasiadis, Julia Chang, Jovana Pavisic, Warren D. Shlomchik> ;Journal of Immunology. 2011 Aug 15
• 1 citation
  Enhancing alloreactivity does not restore GVHD induction but augments skin graft rejection by CD4⁺ effector memory T cells.
  Anderson, B. E., Tang, A. L., Wang, Y., Froicu, M., Rothstein, D. M., McNiff, J. M., Jain, D., Demetris, A. J., Farber, D. L., Shlomchik, W. D., Shlomchik, M. J.> ;European journal of immunology. 2011 Jun 11
• 6 citations
  A crucial role for host APCs in the induction of donor CD4+CD25+ regulatory T cell-mediated suppression of experimental graft-versus-host disease.
  Tawara, I., Shlomchik, W. D., Jones, A., Zou, W., Nieves, E., Liu, C., Toubai, T., Duran-Struuck, R., Sun, Y., Clouthier, S. G., Evers, R., Lowler, K. P., Levy, R. B.,...> ;Journal of immunology (Baltimore, Md. : 1950). 2010 Sep 3
• NK cells delay allograft rejection in lymphopenic hosts by downregulating the homeostatic proliferation of CD8+ T cells.
  Zecher, D., Li, Q., Oberbarnscheidt, M. H., Demetris, A. J., Shlomchik, W. D., Rothstein, D. M., Lakkis, F. G.> ;Journal of immunology (Baltimore, Md. : 1950). 2010 May 21
• NCI First International Workshop on The Biology, Prevention, and Treatment of Relapse After Allogeneic Hematopoietic Stem Cell Transplantation: Report from the Committ...
  Jeffrey S. Miller, Edus H. Warren, Marcel R.M. van den Brink, Jerome Ritz, Warren D. Shlomchik, William J. Murphy, A. John Barrett, Hans-Jochem Kolb, Sergio Giralt, Mi...> ;Biology of Blood and Marrow Transplantation. 2010 May 1
• 18 citations
  NCI first International Workshop on the biology, prevention, and treatment of relapse after allogeneic hematopoietic stem cell transplantation: report from the committ...
  Cairo, M. S., Jordan, C. T., Maley, C. C., Chao, C. K., Melnick, A., Armstrong, S. A., Shlomchik, W. D., Molldrem, J. J., Ferrone, S., Mackall, C. L., Zitvogel, L., Bi...> ;Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation. 2010 Mar 17
• 22 citations
  An Innate Response to Allogeneic Nonself Mediated by Monocytes
  Daniel Zecher, Nico van Rooijen, David M. Rothstein, Warren D. Shlomchik, Fadi G. Lakkis> ;Journal of Immunology. 2009 Dec 15
• Central memory CD8+ T cells induce graft-versus-host disease and mediate graft-versus-leukemia.
  Hong Zheng, Catherine Matte-Martone, Dhanpat Jain, Jennifer M. McNiff, Warren D. Shlomchik> ;Journal of Immunology. 2009 May 15
• MyD88-dependent, superoxide-initiated inflammation is necessary for flow-mediated inward remodeling of conduit arteries
  Paul C. Tang, Lingfeng Qin, Jacek Zielonka, Jing Zhou, Catherine Matte-Martone, Sonia Bergaya, Nico van Rooijen, Warren D. Shlomchik, Wang Min, William C. Sessa, Jorda...> ;Journal of Experimental Medicine. 2008 Dec 22
• 8 citations
  Characterization of a novel gain of function glucocorticoid receptor knock-in mouse.
  Zhang, J., Ge, R., Matte-Martone, C., Goodwin, J. E., Shlomchik, W. D., Mamula, M. J., Kooshkabadi, A., Hardy, M. P., Geller, D. S.> ;The Journal of biological chemistry. 2008 Nov 20
• CD8+ but not CD4+ T cells require cognate interactions with target tissues to mediate GVHD across only minor H antigens, whereas both CD4+ and CD8+ T cells require dir...
  Catherine Matte-Martone, Jinli Liu, Dhanpat Jain, Jennifer M. McNiff, Warren D. Shlomchik> ;Blood. 2008 Apr 1
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Lectures

• CD8+ Effector T Cell Migration into the Bone Marrow of Transplanted Mice: Influence of Gvhd, Leukemia Cells and Variable Dependence on Chemokine Receptors 
  2018 ASH Annual Meeting - San Diego, CA - 12/1/2018
• The Making of Memory 
  60th American Society of Hematology Annual Meeting - 12/1/2018