WaylandWing-LunChengMDPhD
Anesthesiology • Saint Louis, MOCardiothoracic Anesthesiology
Assistant Professor
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Office
660 South Euclid Ave
Saint Louis, MO 63110Phone+1 314-273-7958Fax+1 314-362-6978- Is this information wrong?
Summary
- My laboratory studies the structural mechanisms of ion channel gating and pharmacology. We use cryo-EM, photolabeling, mass spectrometry, electrophysiology and MD simulations.
Education & Training
Washington University/B-JH/SLCH ConsortiumFellowship, Adult Cardiothoracic Anesthesiology, 2016 - 2017- Washington University/B-JH/SLCH ConsortiumResidency, Anesthesiology, 2012 - 2016
- Washington University in St. Louis School of MedicineClass of 2012
Certifications & Licensure
MO State Medical License 2015 - 2025- American Board of Anesthesiology Anesthesiology
Publications & Presentations
PubMed
- 4 citationsLipid nanodisc scaffold and size alter the structure of a pentameric ligand-gated ion channel.Vikram Dalal, Mark J Arcario, John T Petroff 2nd, Brandon K Tan, Noah M Dietzen, Michael J Rau, James A J Fitzpatrick, Grace Brannigan, Wayland W L Cheng> ;Nature Communications. 2024 Jan 2
- 5 citationsMembrane phospholipids control gating of the mechanosensitive potassium leak channel TREK1.Philipp A M Schmidpeter, John T Petroff 2nd, Leila Khajoueinejad, Aboubacar Wague, Cheryl Frankfater, Wayland W L Cheng, Crina M Nimigean, Paul M Riegelhaupt> ;Nature Communications. 2023 Feb 25
- 13 citationsOpen-channel structure of a pentameric ligand-gated ion channel reveals a mechanism of leaflet-specific phospholipid modulation.John T Petroff 2nd, Noah M Dietzen, Ezry Santiago-McRae, Brett Deng, Maya S Washington, Lawrence J Chen, K Trent Moreland, Zengqin Deng, Michael Rau, James A J Fitzpat...> ;Nature Communications. 2022 Nov 17
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Press Mentions
5 Physician-Scientists Named Dean’s Scholars – Washington University School of Medicine in St. LouisJune 22nd, 2023
Grant Support
- Lipid Modulation of Ligand-Gated Ion ChannelsNIH2020–2025
- CHARACTERIZING NEUROSTEROID BINDING IN THE GABA(A) RECEPTOR USING TOP-DOWN MASS SPECTROMETRYNIH2017–2020
- Pilot and feasibilityCIMED2017–2019
Committees
- Member, T32 Training Program Executive Advisory Committee 2018 - Present
Hospital Affiliations
Barnes-Jewish HospitalSaint Louis, Missouri
External Links
- Labhttp://wchenglab.org
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