WeiZhengMD

PubMed

• High-Throughput Zika Viral Titer Assay for Rapid Screening of Antiviral Drugs.
  Lee, E. M.,Titus, S. A.,Xu, M.,Tang, H.,Zheng, W.> ;Assay Drug Dev Technol. 2019 Apr 09
• "Real-Time" High-Throughput Drug and Synergy Testing for Multidrug-Resistant Bacterial Infection: A Case Report.
  Sun, W.,Hesse, S.,Xu, M.,Childs, R. W.,Zheng, W.,Williamson, P. R.> ;Front Med (Lausanne). 2018 Oct 10
• Small Molecules Identified from a Quantitative Drug Combinational Screen Resensitize Cisplatin's Response in Drug-Resistant Ovarian Cancer Cells.
  Sima, N.,Sun, W.,Gorshkov, K.,Shen, M.,Huang, W.,Zhu, W.,Xie, X.,Zheng, W.,Cheng, X.> ;Transl Oncol. 2018 Jul 10
• Genome-Wide Meta-Analysis Identifies Five New Susceptibility Loci for Pancreatic Cancer
  Charles Fuchs, Emily White, Eric A. Klein, Wei Zheng, Stephen Chanock, Alison P. Klein> ;Nature.
• Epitranscriptomic m6A Regulation of Axon Regeneration in the Adult Mammalian Nervous System
  Wei Zheng, MD> ;Cell Press. 2018 Jan 19
• Astrocytes as Targets for Drug Discovery
  Wei Zheng, MD> ;Drug Discovery Today. 2018 Jan 11
• 29 citations
  Quantitative high-throughput screening identifies cytoprotective molecules that enhance SUMO conjugation via the inhibition of SUMO-specific protease (SENP)2.
  Joshua D. Bernstock, Daniel Ye, Jayden A. Smith, Yang-ja Lee, Florian Gessler, Adam Yasgar, Jennifer Kouznetsova, Ajit Jadhav, Zhuoran Wang, Stefano Pluchino, Wei Zhen...> ;FASEB Journal. 2017 Dec 19
• Induced Pluripotent Stem Cells for Disease Modeling and Evaluation of Therapeutics for Niemann-Pick Disease Type A.
  Long Y, Xu M, Li R, Dai S, Beers J, Chen G, Soheilian F, Baxa U, Wang M, Marugan JJ, Muro S, Li Z, Brady R, Zheng W> ;Stem Cells Transl Med. 2016-12-01
• ML372 blocks SMN ubiquitination and improves spinal muscular atrophy pathology in mice.
  Abera MB, Xiao J, Nofziger J, Titus S, Southall N, Zheng W, Moritz KE, Ferrer M, Cherry JJ, Androphy EJ, Wang A, Xu X, Austin C, Fischbeck KH, Marugan JJ, Burnett BG> ;JCI Insight. 2016-11-17
• Molecular signatures associated with ZIKV exposure in human cortical neural progenitors.
  Zhang F, Hammack C, Ogden SC, Cheng Y, Lee EM, Wen Z, Qian X, Nguyen HN, Li Y, Yao B, Xu M, Xu T, Chen L, Wang Z, Feng H, Huang W, Yoon K, Shan C, Huang L, Qin Z, Chri...> ;Nucleic Acids Res.. 2016-10-14
• Identification of small-molecule inhibitors of Zika virus infection and induced neural cell death via a drug repurposing screen.
  Xu M, Lee EM, Wen Z, Cheng Y, Huang W, Qian X, Tcw J, Kouznetsova J, Ogden SC, Hammack C, Jacob F, Nguyen HN, Itkin M, Hanna C, Shinn P, Allen C, Michael SG, Simeonov ...> ;Nat. Med.. 2016-10-01
• Review Post Screen Drug Combination Therapy Increases Successful Drug Repositioning
  Wei Zheng, MD> ;ScienceDirect. 2016 Jun 01
• Identification of HDAC Inhibitors Using a Cell-Based HDAC I/II Assay.
  Hsu C, Shou D, Huang R, Khuc T, Dai S, Zheng W, Klumpp-Thomas C, Xia M> ;J Biomol Screen. 2016-07-01
• High-Throughput Phenotypic Screening of Human Astrocytes to Identify Compounds That Protect Against Oxidative Stress.
  Thorne N, Malik N, Shah S, Zhao J, Class B, Aguisanda F, Southall N, Xia M, McKew JC, Rao M, Zheng W> ;Stem Cells Transl Med. 2016-05-01
• Treatment Paradigms for Retinal and Macular Diseases Using 3-D Retina Cultures Derived From Human Reporter Pluripotent Stem Cell Lines.
  Kaewkhaw R, Swaroop M, Homma K, Nakamura J, Brooks M, Kaya KD, Chaitankar V, Michael S, Tawa G, Zou J, Rao M, Zheng W, Cogliati T, Swaroop A> ;Invest. Ophthalmol. Vis. Sci.. 2016-04-01
• Dynamical Behaviors of Multiple Equilibria in Competitive Neural Networks With Discontinuous Nonmonotonic Piecewise Linear Activation Functions.
  Nie X, Zheng WX> ;IEEE Trans Cybern. 2016-03-01
• Discovery, Optimization, and Characterization of Novel Chlorcyclizine Derivatives for the Treatment of Hepatitis C Virus Infection.
  He S, Xiao J, Dulcey AE, Lin B, Rolt A, Hu Z, Hu X, Wang AQ, Xu X, Southall N, Ferrer M, Zheng W, Liang TJ, Marugan JJ> ;J. Med. Chem.. 2016-02-11
• Synchronization and State Estimation of a Class of Hierarchical Hybrid Neural Networks With Time-Varying Delays.
  Zhang L, Zhu Y, Zheng WX> ;IEEE Trans Neural Netw Learn Syst. 2016-02-01
• High-Throughput Screening, Discovery, and Optimization To Develop a Benzofuran Class of Hepatitis C Virus Inhibitors.
  He S, Jain P, Lin B, Ferrer M, Hu Z, Southall N, Hu X, Zheng W, Neuenswander B, Cho C, Chen Y, Worlikar SA, Aubé J, Larock RC, Schoenen FJ, Marugan JJ, Liang TJ, Frank...> ;ACS Comb Sci. 2015-10-12
• Identification of novel anti-hepatitis C virus agents by a quantitative high throughput screen in a cell-based infection assay.
  Hu, Z.,Hu, X.,He, S.,Yim, H. J.,Xiao, J.,Swaroop, M.,Tanega, C.,Zhang, Y. Q.,Yi, G.,Kao, C. C.,Marugan, J.,Ferrer, M.,Zheng, W.,Southall, N.,Liang, T. J.> ;Antiviral Res.. 2015 Oct 31
• ERK and β-Arrestin Interaction: A Converging Point of Signaling Pathways for Multiple Types of Cell Surface Receptors.
  Eishingdrelo, H.,Sun, W.,Li, H.,Wang, L.,Eishingdrelo, A.,Dai, S.,McKew, J. C.,Zheng, W.> ;J Biomol Screen. 2014 Nov 02
• Characterization of large structural genetic mosaicism in human autosomes.
  Machiela, M. J.,Zhou, W.,Sampson, J. N.,Dean, M. C.,Jacobs, K. B.,Black, A.,Brinton, L. A.,Chang, I. S.,Chen, C.,Chen, C.,Chen, K.,Cook, L. S.,Crous Bou, M.,De Vivo, I...> ;Am. J. Hum. Genet.. 2015 Mar 10
• Imputation and subset-based association analysis across different cancer types identifies multiple independent risk loci in the TERT-CLPTM1L region on chromosome 5p15.33.
  Wang, Z.,Zhu, B.,Zhang, M.,Parikh, H.,Jia, J.,Chung, C. C.,Sampson, J. N.,Hoskins, J. W.,Hutchinson, A.,Burdette, L.,Ibrahim, A.,Hautman, C.,Raj, P. S.,Abnet, C. C.,Ad...> ;Hum. Mol. Genet.. 2014 Jul 17
• Discovery of novel antigiardiasis drug candidates.
  Kulakova L, Galkin A, Chen CZ, Southall N, Marugan JJ, Zheng W, Herzberg O> ;Antimicrob. Agents Chemother.. 2014-12-01
• High-Throughput Viability Assay Using an Autonomously Bioluminescent Cell Line with a Bacterial Lux Reporter.
  Class, B.,Thorne, N.,Aguisanda, F.,Southall, N.,McKew, J. C.,Zheng, W.> ;J Lab Autom. 2014 Dec 03
• Join now to see all

Journal Articles

• Advancing Precision Medicine with Personalized Drug Screening  
  Wei Zheng, MD, ScienceDirect