WillChenMD

PubMed

• 8 citations
  Predicting cancer drug TARGETS - TreAtment Response Generalized Elastic-neT Signatures.
  Nicholas R. Rydzewski, Erik Peterson, Joshua M. Lang, Menggang Yu, S. Laura Chang, Martin Sjöström, Hamza Bakhtiar, Gefei Song, Kyle T Helzer, Matthew L Bootsma, Willi...> ;NPJ Genomic Medicine. 2021 Sep 21
• 3 citations
  Publisher Correction: Global absence and targeting of protective immune states in severe COVID-19.
  Alexis J. Combes, Tristan Courau, Nicholas F. Kuhn, Kenneth H. Hu, Arja Ray, William S. Chen, Nayvin W. Chew, Simon J. Cleary, Divyashree Kushnoor, Gabriella C Reeder,...> ;Nature. 2021 Aug 2
• 16 citations
  An integrated functional and clinical genomics approach reveals genes driving aggressive metastatic prostate cancer
  Rajdeep Das, Martin Sjöström, Raunak Shrestha, Christopher Yogodzinski, Emily A. Egusa, Lisa N. Chesner, William S. Chen, Jonathan Chou, Donna K. Dang, Jason T. Swinde...> ;Nature Communications. 2021 Jul 29
• 29 citations
  An artificial intelligence framework integrating longitudinal electronic health records with real-world data enables continuous pan-cancer prognostication
  Olivier Morin, Martin Vallières, Steve Braunstein, Jorge Barrios Ginart, Taman Upadhaya, Henry C. Woodruff, Alex Zwanenburg, Avishek Chatterjee, Javier Villanueva-Meye...> ;Nature Cancer. 2021 Jul 1
• 49 citations
  Global Absence and Targeting of Protective Immune States in Severe COVID-19.
  Alexis J. Combes, Tristan Courau, Nicholas F. Kuhn, Kenneth H. Hu, Arja Ray, William S. Chen, Simon J. Cleary, Nayvin W. Chew, Divyashree Kushnoor, Gabriella C Reeder,...> ;Biorxiv. 2020 Oct 29
• 4 citations
  Global Absence and Targeting of Protective Immune States in Severe COVID-19
  Alexis J. Combes, Tristan Courau, Nicholas F. Kuhn, Kenneth H. Hu, Arja Ray, William S. Chen, Simon J. Cleary, Nayvin W. Chew, Divyashree Kushnoor, Gabriella C Reeder,...> ;Research Square. 2020 Oct 28
• 6 citations
  Autoantibody landscape in patients with advanced prostate cancer
  William S. Chen, Winston A. Haynes, Rebecca Waitz, Kathy Kamath, Agustin Vega-Crespo, Raunak Shrestha, Minlu Zhang, Adam Foye, Ignacio Baselga Carretero, Ivan Perez Ga...> ;Clinical Cancer Research. 2020 Sep 23
• 135 citations
  The DNA methylation landscape of advanced prostate cancer
  Shuang G. Zhao, William S. Chen, Haolong Li, Adam Foye, Meng Zhang, Martin Sjöström, Rahul Aggarwal, Denise Playdle, Arnold Liao, Joshi J. Alumkal, Rajdeep Das, Jonath...> ;Nature Genetics. 2020 Aug 1
• 8 citations
  Copy number loss of 17q22 is associated with enzalutamide resistance and poor prognosis in metastatic castration-resistant prostate cancer
  Xiangnan Guan, Duanchen Sun, Eric Lu, Joshua Urrutia, Robert E. Reiter, Matthew Rettig, Christopher P. Evans, Primo N. Lara, Martin E. Gleave, Tomasz M. Beer, George T...> ;Clinical Cancer Research. 2020 Sep 1
• 3 citations
  Down-regulation of ADRB2 expression is associated with small cell neuroendocrine prostate cancer and adverse clinical outcomes in castration-resistant prostate cancer.
  Daniel Kwon, Li Zhang, David A. Quigley, Adam Foye, William S. Chen, Christopher K. Wong, Felix Y. Feng, Adina M. Bailey, Jiaoti Huang, Joshua M. Stuart, Verena Friedl...> ;Urologic Oncology. 2020 Jul 2
• 5 citations
  Germline polymorphisms associated with impaired survival outcomes and somatic tumor alterations in advanced prostate cancer.
  William S. Chen, Eric L. Feng, Rahul Aggarwal, Adam Foye, Tomasz M. Beer, Joshi J. Alumkal, Martin E. Gleave, Kim N. Chi, Robert E. Reiter, Matthew Rettig, Christopher...> ;Prostate Cancer and Prostatic Diseases. 2020 Jun 1
• 7 citations
  Genomic and clinical characterization of stromal infiltration markers in prostate cancer.
  Brandon A. Mahal, Mohammed Alshalalfa, Shuang G. Zhao, Himisha Beltran, William S. Chen, Fallon E. Chipidza, Elai Davicioni, R. Jeffrey Karnes, Sheng-Yu Ku, Tamara L. ...> ;Cancer. 2020 Apr 1
• 26 citations
  Uncovering axes of variation among single-cell cancer specimens.
  William S. Chen, Nevena Zivanovic, David van Dijk, Guy Wolf, Bernd Bodenmiller, Smita Krishnaswamy> ;Nature Methods. 2020 Jan 13
• 1 citations
  Author Correction: Visualizing structure and transitions in high-dimensional biological data.
  Kevin R. Moon, David van Dijk, Zheng Wang, Scott Gigante, Daniel B. Burkhardt, William S. Chen, Kristina Yim, Antonia van den Elzen, Matthew J. Hirn, Ronald R. Coifman...> ;Nature Biotechnology. 2020 Jan 1
• 356 citations
  Visualizing structure and transitions in high-dimensional biological data
  Kevin R. Moon, David van Dijk, Zheng Wang, Scott Gigante, Daniel B. Burkhardt, William S. Chen, Kristina Yim, Antonia van den Elzen, Matthew J. Hirn, Ronald R. Coifman...> ;Nature Biotechnology. 2019 Dec 1
• 87 citations
  Genomic Drivers of Poor Prognosis and Enzalutamide Resistance in Metastatic Castration-resistant Prostate Cancer.
  William S. Chen, Rahul Aggarwal, Li Zhang, Shuang G. Zhao, George Thomas, Tomasz M. Beer, David A. Quigley, Adam Foye, Denise Playdle, Jiaoti Huang, Paul Lloyd, Eric L...> ;European Urology. 2019 Nov 1
• 145 citations
  Exploring single-cell data with deep multitasking neural networks.
  Matthew Amodio, David van Dijk, Krishnan Srinivasan, William S. Chen, Hussein Mohsen, Kevin R. Moon, Allison M. Campbell, Yujiao Zhao, Xiaomei Wang, Manjunatha M. Venk...> ;Nature Methods. 2019 Oct 7
• 4 citations
  Large-scale assessment of needs in low vision individuals using the Aira assistive technology.
  Brian J. Nguyen, William S. Chen, Allison J Chen, Andrew Utt, Emily Hill, Ryan Apgar, Daniel L. Chao> ;Clinical Ophthalmology. 2019 Sep 20
• 12 citations
  Transcriptomic and Clinical Characterization of Neuropeptide Y Expression in Localized and Metastatic Prostate Cancer: Identification of Novel Prostate Cancer Subtype ...
  Mohammed Alshalalfa, Paul L. Nguyen, Himisha Beltran, William S. Chen, Elai Davicioni, Shuang G. Zhao, Timothy R. Rebbeck, Edward M. Schaeffer, Tamara L. Lotan, Felix ...> ;European Urology Oncology. 2019 Jul 1
• 31 citations
  Novel RB1-Loss Transcriptomic Signature Is Associated with Poor Clinical Outcomes across Cancer Types
  William S. Chen, Mohammed Alshalalfa, Shuang G. Zhao, Yang Liu, Brandon A. Mahal, David A. Quigley, Ting Wei, Elai Davicioni, Timothy R. Rebbeck, Philip W. Kantoff, Ch...> ;Clinical Cancer Research. 2019 Apr 22
• 38 citations
  Clinical and Genomic Implications of Luminal and Basal Subtypes Across Carcinomas
  Shuang G. Zhao, William S. Chen, Rajdeep Das, S. Laura Chang, Scott A. Tomlins, Jonathan Chou, David A. Quigley, Ha X. Dang, Travis J. Barnard, Brandon A. Mahal, Ewan ...> ;Clinical Cancer Research. 2019 Apr 15
• 33 citations
  CDKN2A Copy Number Loss Is an Independent Prognostic Factor in HPV-Negative Head and Neck Squamous Cell Carcinoma.
  William S. Chen, Ranjit S. Bindra, Allen Mo, Thomas J. Hayman, Zain A. Husain, Joseph N. Contessa, Stephen G. Gaffney, Jeffrey P. Townsend, James B. Yu> ;Frontiers in Oncology. 2018 Apr 4
• 7 citations
  Synergistic drug combinations from electronic health records and gene expression.
  Yen Low, Aaron C Daugherty, Elizabeth A. Schroeder, William S. Chen, Tina Seto, Susan C. Weber, Michael Lim, Trevor Hastie, Maya B. Mathur, Manisha Desai, Carl Farring...> ;Journal of the American Medical Informatics Association. 2017 May 1
• 3 citations
  Radiation-Specific Clinical Data Should Be Included in Existing Large-Scale Genomic Datasets.
  William S. Chen, Jeffrey P. Townsend, James B. Yu> ;International Journal of Radiation Oncology, Biology, Physics. 2017 May 1
• 27 citations
  Diameter of Solid Tumor Component Alone Should be Used to Establish T Stage in Lung Adenocarcinoma.
  Bryan M. Burt, Ann N. Leung, Masahiro Yanagawa, William S. Chen, Shawn S. Groth, Chuong D. Hoang, Viswam S. Nair, Joseph B. Shrager> ;Annals of Surgical Oncology. 2015 Jul 31
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