WilliamBainMD

PubMed

• Damage sensing through TLR9 Promotes Viral Clearance and Recovery During Influenza Infection.
  Jooyoung Kim, Yifan Yuan, Karen Agaronyan, Amy Zhao, Victoria D Wang, Gayatri Gupta, Heran Essayas, Ayelet Kaminski, John McGovern, Sheeline Yu, Samuel Woo, Chris J Le...> ;Biorxiv. 2024 Mar 6
• Glucocorticoid use in acute respiratory failure from pulmonary causes and association with early changes in the systemic host immune response.
  Nameer Al-Yousif, Seyed M Nouraie, Matthew J Broerman, Yingze Zhang, Tomeka L Suber, John Evankovich, William G Bain, Georgios D Kitsios, Bryan J McVerry, Faraaz A Shah> ;Intensive Care Medicine Experimental. 2024 Mar 5
• "Now We Got Bad Blood": Beyond Phenotype Labels in an "Era" of Meta-omics in Critical Illness.
  Georgios D Kitsios, William Bain> ;American Journal of Respiratory and Critical Care Medicine. 2024 Apr 1
• Lung Epithelium Releases Growth Differentiation Factor 15 in Response to Pathogen-mediated Injury.
  Faraaz A Shah, Harinath Bahudhanapati, Mao Jiang, Mohammadreza Tabary, Rick van der Geest, Nathanial J Tolman, Megan Kochin, Zeyu Xiong, Nameer Al-Yousif, Khaled Sayed...> ;American Journal of Respiratory Cell and Molecular Biology. 2024 Feb 1
• In vivo evolution of a Klebsiella pneumoniae capsule defect with wcaJ mutation promotes complement-mediated opsono-phagocytosis during recurrent infection.
  Bain, W., Ahn, B., Peñaloza, H., McElheny, C., Tolman, N., van der Geest, R., Gonzalez-Ferrer, S., Chen, N., An, X., Hosuru, R., Tabary, M., Papke, E., Kohli, N., Faro...> ;The Journal of Infectious Diseases. 2024 Jan 25
• STAT1 Employs Myeloid Cell-Extrinsic Mechanisms to Regulate the Neutrophil Response and Provide Protection against Invasive Klebsiella pneumoniae Lung Infection.
  Gonzalez-Ferrer, S., Peñaloza, H., van der Geest, R., Xiong, Z., Gheware, A., Tabary, M., Kochin, M., Dalton, K., Zou, H., Lou, D., Lockwood, K., Zhang, Y., Bain, W., ...> ;Immunohorizons. 2024 Jan 1
• A common single nucleotide polymorphism is associated with inflammation and critical illness outcomes.
  Fayten El-Dehaibi, Ruben Zamora, Josiah Radder, Jinling Yin, Ashti M Shah, Rami A Namas, Michelle Situ, Yanwu Zhao, William Bain, Alison Morris, Bryan J McVerry, Derek...> ;Iscience. 2023 Dec 15
• 2 citations
  Trajectories of Host-Response Subphenotypes in Patients With COVID-19 Across the Spectrum of Respiratory Support.
  Lu, M., Drohan, C., Bain, W., Shah, F., Bittner, M., Evankovich, J., Prendergast, N., Hensley, M., Suber, T., Fitzpatrick, M., Ramanan, R., Murray, H., Schaefer, C., Q...> ;CHEST Critical Care. 2023 Dec 1
• 2 citations
  Noninvasive diagnosis of secondary infections in COVID-19 by sequencing of plasma microbial cell-free DNA.
  Grace Lisius, Radha Duttagupta, Asim A Ahmed, Matthew Hensley, Nameer Al-Yousif, Michael Lu, William Bain, Faraaz Shah, Timothy A Blauwkamp, Sivan Bercovici, Caitlin S...> ;Iscience. 2023 Nov 17
• BATF2 enhances proinflammatory cytokine responses in macrophages and improves early host defense against pulmonaryinfection.
  Rick van der Geest, Hernán F Peñaloza, Zeyu Xiong, Shekina Gonzalez-Ferrer, Xiaojing An, Huihua Li, Hongye Fan, Mohammadreza Tabary, S Mehdi Nouraie, Yanwu Zhao, Yingz...> ;American Journal of Physiology. Lung Cellular and Molecular Physiology. 2023 Nov 1
• 2 citations
  Research Bronchoscopy Standards and the Need for Noninvasive Sampling of the Failing Lungs.
  William Bain, Julie A Bastarache, Aartik Sarma, Rebecca M Baron, Bryan J McVerry, Georgios D Kitsios, Noel G McElvaney> ;Annals of the American Thoracic Society. 2024 Jan 1
• Prognostic Insights from Longitudinal Multicompartment Study of Host-Microbiota Interactions in Critically Ill Patients.
  Georgios D Kitsios, Khaled Sayed, Adam Fitch, Haopu Yang, Noel Britton, Faraaz Shah, William Bain, John W Evankovich, Shulin Qin, Xiaohong Wang, Kelvin Li, Asha Patel,...> ;Research Square. 2023 Sep 26
• Prognostic Insights from Longitudinal Multicompartment Study of Host-Microbiota Interactions in Critically Ill Patients.
  Georgios D Kitsios, Khaled Sayed, Adam Fitch, Haopu Yang, Noel Britton, Faraaz Shah, William Bain, John W Evankovich, Shulin Qin, Xiaohong Wang, Kelvin Li, Asha Patel,...> ;Medrxiv. 2023 Sep 26
• evolution of acapsule defect promotes complement-mediated opsono-phagocytosis and persistence during recurrent infection.
  William Bain, Brian Ahn, Hernán F Peñaloza, Christi L McElheny, Nathanial Tolman, Rick van der Geest, Shekina Gonzalez-Ferrer, Nathalie Chen, Xiaojing An, Ria Hosuru, ...> ;Biorxiv. 2023 Jun 1
• 2 citations
  Serum metabolomic signatures of fatty acid oxidation defects differentiate host-response subphenotypes of acute respiratory distress syndrome.
  Tomeka L Suber, Stacy G Wendell, Steven J Mullett, Benjamin Zuchelkowski, William Bain, Georgios D Kitsios, Bryan J McVerry, Prabir Ray, Anuradha Ray, Rama K Mallampal...> ;Respiratory Research. 2023 May 20
• 2 citations
  Respiratory Fungal Communities are Associated with Systemic Inflammation and Predict Survival in Patients with Acute Respiratory Failure.
  Noel Britton, Haopu Yang, Adam Fitch, Kelvin Li, Khaled Seyed, Rui Guo, Shulin Qin, Yingze Zhang, William Bain, Faraaz Shah, Partha Biswas, Wonseok Choi, Malcolm Finke...> ;Medrxiv. 2023 May 16
• 1 citations
  Factor H preserves alternative complement function during ARDS, linked to improved survival.
  William Bain, Mohammadreza Tabary, Sara R Moore, Xiaojing An, Georgios D Kitsios, Bryan J McVerry, Prabir Ray, Anuradha Ray, Rama K Mallampalli, Viviana P Ferreira, Ja...> ;ERJ Open Research. 2023 May 1
• 4 citations
  Distinct profiles of host responses between plasma and lower respiratory tract during acute respiratory failure.
  Georgios D Kitsios, Seyed Mehdi Nouraie, Shulin Qin, Yingze Zhang, Prabir Ray, Anuradha Ray, Janet S Lee, Alison Morris, Bryan J McVerry, William Bain> ;ERJ Open Research. 2023 May 1
• 3 citations
  Inter-rater reliability and prognostic value of baseline Radiographic Assessment of Lung Edema (RALE) scores in observational cohort studies of inpatients with COVID-19.
  Nameer Al-Yousif, Saketram Komanduri, Hafiz Qurashi, Anatoliy Korzhuk, Halimat O Lawal, Nicholas Abourizk, Caitlin Schaefer, Kevin J Mitchell, Catherine M Dietz, Ellen...> ;BMJ Open. 2023 Jan 12
• 2 citations
  Phagocytosis is a primary determinant of pulmonary clearance of clinicalisolates.
  Rick van der Geest, Hongye Fan, Hernán F Peñaloza, William G Bain, Zeyu Xiong, Naina Kohli, Emily Larson, Mara L G Sullivan, Jonathan M Franks, Donna B Stolz, Ryota It...> ;Frontiers in Cellular and Infection Microbiology. 2023 Jan 1
• TMPRSS11E-dward Scissorhands? Proteolysis Potentiates Lung Inflammation during Pathogen Insult.
  Xiaojing An, William Bain> ;American Journal of Respiratory Cell and Molecular Biology. 2023 Apr 1
• Trajectories of host-response biomarkers and inflammatory subphenotypes in COVID-19 patients across the spectrum of respiratory support.
  Michael Lu, Callie Drohan, William Bain, Faraaz A Shah, Matthew Bittner, John Evankovich, Niall Prendergast, Matthew Hensley, Tomeka Suber, Meghan Fitzpatrick, Raj Ram...> ;Medrxiv. 2022 Nov 29
• 9 citations
  Antibodies targeting conserved non-canonical antigens and endemic coronaviruses associate with favorable outcomes in severe COVID-19.
  Sai Preetham Peddireddy, Syed A Rahman, Anthony R Cillo, Godhev Manakkat Vijay, Ashwin Somasundaram, Creg J Workman, William Bain, Bryan J McVerry, Barbara Methe, Jane...> ;Cell Reports. 2022 Jun 28
• 4 citations
  Stability of SARS-CoV-2-Encoded Proteins and Their Antibody Levels Correlate with Interleukin 6 in COVID-19 Patients.
  Wangyang Li, Georgios D Kitsios, William Bain, Chenxiao Wang, Tiao Li, Kristen V Fanning, Rushikesh Deshpande, Xuebin Qin, Alison Morris, Janet S Lee, Chunbin Zou> ;Msystems. 2022 Jun 28
• Plasma SARS-CoV-2 RNA Levels as a Biomarker of Lower Respiratory Tract SARS-CoV-2 Infection in Critically Ill Patients With COVID-19.
  Jana L Jacobs, Asma Naqvi, Faraaz A Shah, Valerie F Boltz, Mary F Kearney, Bryan J McVerry, Prabir Ray, Caitlin Schaefer, Meghan Fitzpatrick, Barbara Methé, Janet S Le...> ;The Journal of Infectious Diseases. 2022 Dec 13
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