WilliamMonroeCanfieldMD

PubMed

• 6 citations
  Species-specific differences in the processing of acid α-glucosidase are due to the amino acid identity at position 201.
  Rodney J. Moreland, Sheri Higgins, AnQiang Zhou, Peter VanStraten, Robert D. Cauthron, Michael S. Brem, Beverly J. McLarty, Mariko Kudo, William M. Canfield> ;Gene. 2012 Jan 1
• 31 citations
  Structural basis for recognition of phosphodiester-containing lysosomal enzymes by the cation-independent mannose 6-phosphate receptor
  Linda J. Olson, Francis C. Peterson, Alicia C. Castonguay, Richard N. Bohnsack, Mariko Kudo, Russell Gotschall, William M. Canfield, Brian F. Volkman, Nancy M. Dahms> ;Proceedings of the National Academy of Sciences of the United States of America. 2010 Jul 13
• 51 citations
  Functions of the α, β, and γ Subunits of UDP-GlcNAc:Lysosomal Enzyme N-Acetylglucosamine-1-phosphotransferase *
  Yi Qian, Intaek Lee, Wang Sik Lee, Meiqian Qian, Mariko Kudo, William M. Canfield, Peter Lobel, Stuart Kornfeld> ;The Journal of Biological Chemistry. 2010 Jan 29
• 50 citations
  Cation-independent mannose 6-phosphate receptor: A composite of distinct phosphomannosyl binding sites
  Richard N. Bohnsack, Xuezheng Song, Linda J. Olson, Mariko Kudo, Russell Gotschall, William M. Canfield, Richard D. Cummings, David F. Smith, Nancy M. Dahms> ;The Journal of Biological Chemistry. 2009 Dec 11
• 116 citations
  Glycoengineered Acid α-Glucosidase With Improved Efficacy at Correcting the Metabolic Aberrations and Motor Function Deficits in a Mouse Model of Pompe Disease
  Yunxiang Zhu, Ji-Lei Jiang, Nathan Gumlaw, Jinhua Zhang, Scott D. Bercury, Robin J. Ziegler, Karen Lee, Mariko Kudo, William M. Canfield, Tim Edmunds, Canwen Jiang, Ro...> ;Molecular Therapy. 2009 Jun 1
• 44 citations
  Molecular order in mucolipidosis II and III nomenclature
  Sara S. Cathey, Mariko Kudo, Stephan Tiede, Annick Raas-Rothschild, Thomas Braulke, Michael Beck, Harold A. Taylor, William M. Canfield, Jules G. Leroy, Elizabeth F. N...> ;American Journal of Medical Genetics. Part A. 2008 Feb 15
• 39 citations
  Domain 5 of the cation-independent mannose 6-phosphate receptor preferentially binds phosphodiesters (mannose 6-phosphate N-acetylglucosamine ester).
  Carrie A. Chavez, Richard N. Bohnsack, Mariko Kudo, Russell Gotschall, William M. Canfield, Nancy M. Dahms> ;Biochemistry. 2007 Oct 10
• 41 citations
  Structural Requirements for Efficient Processing and Activation of Recombinant Human UDP-N-acetylglucosamine:Lysosomal-enzyme-N-acetylglucosamine-1-phosphotransferase
  Mariko Kudo, William M. Canfield> ;The Journal of Biological Chemistry. 2006 Apr 28
• 111 citations
  Mucolipidosis II (I-Cell Disease) and Mucolipidosis IIIA (Classical Pseudo-Hurler Polydystrophy) Are Caused by Mutations in the GlcNAc-Phosphotransferase α/β–Subunits ...
  Mariko Kudo, Michael S. Brem, William M. Canfield> ;American Journal of Human Genetics. 2006 Mar 1
• 86 citations
  The alpha- and beta-subunits of the human UDP-N-acetylglucosamine:lysosomal enzyme N-acetylglucosamine-1-phosphotransferase [corrected] are encoded by a single cDNA.
  Mariko Kudo, Ming Bao, Anil D'Souza, Fu Ying, Huaqin Pan, Bruce A. Roe, William M. Canfield> ;The Journal of Biological Chemistry. 2005 Oct 28
• 46 citations
  Hyaluronan Biosynthesis by Class I Streptococcal Hyaluronan Synthases Occurs at the Reducing End
  Valarie L. Tlapak-Simmons, Christina A. Baron, Russell Gotschall, Dewan Haque, William M. Canfield, Paul H. Weigel> ;The Journal of Biological Chemistry. 2005 Apr 1
• 100 citations
  Lysosomal Acid α-Glucosidase Consists of Four Different Peptides Processed from a Single Chain Precursor
  Rodney J. Moreland, Xiaoying Jin, X. Kate Zhang, Roger W. Decker, Karen L. Albee, Karen L. Lee, Robert D. Cauthron, Kevin Brewer, Tim Edmunds, William M. Canfield> ;The Journal of Biological Chemistry. 2005 Feb 25
• 33 citations
  Human mannose 6-phosphate-uncovering enzyme is synthesized as a proenzyme that is activated by the endoprotease furin.
  Hung Do, Wang Sik Lee, Tracy Hollowell, William M. Canfield, Stuart Kornfeld, Pradipta Ghosh> ;The Journal of Biological Chemistry. 2002 Aug 16
• 198 citations
  Cloning and Expression of Human Core 1 β1,3-Galactosyltransferase
  Tongzhong Ju, Kevin Brewer, Anil D'Souza, Richard D. Cummings, William M. Canfield> ;The Journal of Biological Chemistry. 2002 Jan 4
• 88 citations
  Purification, characterization, and subunit structure of rat core 1 β1,3-galactosyltransferase
  Tongzhong Ju, Richard D. Cummings, William M. Canfield> ;The Journal of Biological Chemistry. 2002 Jan 4
• 134 citations
  Molecular basis of variant pseudo-Hurler polydystrophy (mucolipidosis IIIC)
  Annick Raas-Rothschild, Valérie Cormier-Daire, Ming Bao, Emmanuelle Génin, Rémi Salomon, Kevin Brewer, Marsha Zeigler, Hanna Mandel, Steve Toth, Bruce A. Roe, Arnold M...> ;The Journal of Clinical Investigation. 2000 Mar 1
• 31 citations
  Molecular Cloning and Functional Expression of Two Splice Forms of Human N-Acetylglucosamine-1-phosphodiester α-N-Acetylglucosaminidase
  Rosalind Kornfeld, Ming Bao, Kevin Brewer, Carolyn Noll, William M. Canfield> ;The Journal of Biological Chemistry. 1999 Nov 12
• 156 citations
  A novel glycosulfopeptide binds to P-selectin and inhibits leukocyte adhesion to P-selectin.
  Anne Leppänen, Padmaja Mehta, Ying-Bin Ouyang, Tongzhong Ju, Jari Helin, Kevin L. Moore, Irma van Die, William M. Canfield, Rodger P. McEver, Richard D. Cummings> ;The Journal of Biological Chemistry. 1999 Aug 27
• 22 citations
  Purification and Multimeric Structure of BovineN-Acetylglucosamine-1-phosphodiester α-N-Acetylglucosaminidase
  Rosalind Kornfeld, Ming Bao, Kevin Brewer, Carolyn Noll, William M. Canfield> ;The Journal of Biological Chemistry. 1998 Sep 4
• 10 citations
  Synthesis of 5-azido-UDP-N-acetylhexosamine photoaffinity analogs and radiolabeled UDP-N-acetylhexosamines.
  Prasanna Sunthankar, Irena Pastuszak, Agnieszka Rooke, Alan D. Elbein, Ivo van de Rijn, William M. Canfield, Richard R. Drake> ;Analytical Biochemistry. 1998 May 1
• 50 citations
  Bovine UDP-N-acetylglucosamine:Lysosomal-enzyme N-Acetylglucosamine-1-phosphotransferase II. ENZYMATIC CHARACTERIZATION AND IDENTIFICATION OF THE CATALYTIC SUBUNIT
  Ming Bao, B. J. M. Elmendorf, Booth Jl, Drake Rr, William M. Canfield> ;The Journal of Biological Chemistry. 1996 Dec 6
• 98 citations
  Bovine UDP-N-acetylglucosamine:Lysosomal-enzyme N-Acetylglucosamine-1-phosphotransferase I: PURIFICATION AND SUBUNIT STRUCTURE *
  Ming Bao, J. Leland Booth, B. Jean Elmendorf, William M. Canfield> ;The Journal of Biological Chemistry. 1996 Dec 6
• 54 citations
  Residues Throughout the Cytoplasmic Domain Affect the Internalization Efficiency of P-selectin
  Hendra Setiadi, Magali Disdier, Samuel A. Green, William M. Canfield, Rodger P. McEver> ;The Journal of Biological Chemistry. 1995 Nov 10
• 31 citations
  Characterization of the signal for rapid internalization of the bovine mannose 6-phosphate/insulin-like growth factor-II receptor.
  M Jadot, W M Canfield, W Gregory, S Kornfeld> ;The Journal of Biological Chemistry. 1992 Jun 5
• 23 citations
  Localization of the signal for rapid internalization of the bovine cation-independent mannose 6-phosphate/insulin-like growth factor-II receptor to amino acids 24-29 o...
  W M Canfield, K F Johnson, R D Ye, W Gregory, S Kornfeld> ;The Journal of Biological Chemistry. 1991 Mar 25
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