WilliamAllenCarrollMD

PubMed

• Oligonucleotide PIK3CA/Chromosome 3 Dual in Situ Hybridization Automated Assay with Improved Signals, One-Hour Hybridization, and No Use of Blocking DNA
  Wenjun Zhang, Antony Hubbard, Leslie Baca-Parkinson, Stacey Stanislaw, Frank Vladich, Mark D. Robida, James Grille, Daniel Maxwell, Tsu-Shuen Tsao, William Carroll, Tr...> ;The Journal of Molecular Diagnostics. 2015 Sep 1
• Synthesis and in vitro activity of N-benzyl-1-(2,3-dichlorophenyl)-1H-tetrazol-5-amine P2X(7) antagonists.
  Perez-Medrano, A.,Donnelly-Roberts, D. L.,Florjancic, A. S.,Nelson, D. W.,Li, T.,Namovic, M. T.,Peddi, S.,Faltynek, C. R.,Jarvis, M. F.,Carroll, W. A.> ;Bioorg Med Chem Lett. 2011 Jun 1
• Discovery and biological evaluation of novel cyanoguanidine P2X(7) antagonists with analgesic activity in a rat model of neuropathic pain.
  Perez-Medrano, A., Donnelly-Roberts, D.L., Honore, P., Hsieh, G.C., Namovic, M.T., Peddi, S., Shuai, Q., Wang, Y., Faltynek, C.R., Jarvis, M.F., Carroll, W.A.> ;J Med Chem. 2009-05-28
• Structure-activity relationship studies on N'-aryl carbohydrazide P2X7 antagonists.
  Nelson, D.W., Sarris, K., Kalvin, D.M., Namovic, M.T., Grayson, G., Donnelly-Roberts, D.L., Harris, R., Honore, P., Jarvis, M.F., Faltynek, C.R., Carroll, W.A.> ;J Med Chem. 2008 May 22
• Discovery and biological evaluation of 5-aryl-2-furfuramides, potent and selective blockers of the Nav1.8 sodium channel with efficacy in models of neuropathic and inf...
  Kort, M.E., Drizin, I., Gregg, R.J., Scanio, M.C., Shi, L., Gross, M.F., Atkinson, R.N., Johnson, M.S., Pacofsky, G.J., Thomas, J.B., Carroll, W.A., Krambis, M.J., Liu...> ;J Med Chem. 2008 Feb 14
• Structure-activity studies of novel cyanoguanidine ATP-sensitive potassium channel openers for the treatment of overactive bladder.
  Perez-Medrano, A., Brune, M.E., Buckner, S.A., Coghlan, M.J., Fey, T.A., Gopalakrishnan, M., Gregg, R.J., Kort, M.E., Scott, V.E., Sullivan, J.P., Whiteaker, K.L., Car...> ;J Med Chem. 2007 Nov 29
• Effects of substitution on 9-(3-bromo-4-fluorophenyl)-5,9-dihydro-3H,4H-2,6-dioxa-4- azacyclopenta[b]naphthalene-1,8-dione, a dihydropyridine ATP-sensitive potassium c...
  Altenbach, R.J., Brune, M.E., Buckner, S.A., Coghlan, M.J., Daza, A.V., Fabiyi, A., Gopalakrishnan, M., Henry, R.F., Khilevich, A., Kort, M.E., Milicic, I., Scott, V.E...> ;J Med Chem. 2006 Nov 16
• Structure-activity relationship studies on a series of novel, substituted 1-benzyl-5-phenyltetrazole P2X7 antagonists.
  Nelson, D.W., Gregg, R.J., Kort, M.E., Perez-Medrano, A., Voight, E.A., Wang, Y., Grayson, G., Namovic, M.T., Donnelly-Roberts, D.L., Niforatos, W., Honore, P., Jarvis...> ;J Med Chem. 2006 Jun 15
• Pharmacological characterization of the novel dihydropyridine potassium channel opener, (9R)-9-(3-iodo-4-methylphenyl)-5,9-dihydro-3H-furo[3,4-b]pyrano[4,3-e]pyridine-...
  Fryer, R.M., Rakestraw, P.A., Preusser, L.C., Brune, M.E., Carroll, W.A., Buckner, S.A., Shieh, C., King, L.L., Marsh, K.C., Gopalakrishnan, M., Cox, B.F., Reinhart, G.A.> ;J Cardiovasc Pharmacol. 2005 Aug
• Synthesis and structure-activity relationships of a novel series of 2,3,5,6,7,9-hexahydrothieno[3,2-b]quinolin-8(4H)-one 1,1-dioxide K(ATP) channel openers: discovery ...
  Carroll, W.A., Altenbach, R.J., Bai, H., Brioni, J.D., Brune, M.E., Buckner, S.A., Cassidy, C., Chen, Y., Coghlan, M.J., Daza, A.V., Drizin, I., Fey, T.A., Fitzgerald,...> ;J Med Chem. 2004 Jun 3
• Synthesis and structure-activity relationships of a novel series of tricyclic dihydropyridine-based KATP openers that potently inhibit bladder contractions in vitro.
  Carroll, W.A., Agrios, K.A., Altenbach, R.J., Buckner, S.A., Chen, Y., Coghlan, M.J., Daza, A.V., Drizin, I., Gopalakrishnan, M., Henry, R.F., Kort, M.E., Kym, P.R., M...> ;J Med Chem. 2004 Jun 3
• Synthesis and structure-activity studies on N-[5-(1H-imidazol-4-yl)-5,6,7,8-tetrahydro-1-naphthalenyl]methanesulfonamide, an imidazole-containing alpha(1A)-adrenocepto...
  Altenbach, R.J., Khilevich, A., Kolasa, T., Rohde, J.J., Bhatia, P.A., Patel, M.V., Searle, X.B., Yang, F., Bunnelle, W.H., Tietje, K., Bayburt, E.K., Carroll, W.A., M...> ;J Med Chem. 2004 Jun 3
• [125I]A-312110, a novel high-affinity 1,4-dihydropyridine ATP-sensitive K+ channel opener: characterization and pharmacology of binding.
  Davis-Taber, R., Molinari, E.J., Altenbach, R.J., Whiteaker, K.L., Shieh, C., Rotert, G., Buckner, S.A., Malysz, J., Milicic, I., McDermott, J.S., Gintant, G.A., Coghl...> ;Mol Pharmacol. 2003 Jul
• (-)-(9S)-9-(3-Bromo-4-fluorophenyl)-2,3,5,6,7,9-hexahydrothieno[3,2-b]quinolin-8(4H)-one 1,1-dioxide (A-278637): a novel ATP-sensitive potassium channel opener efficac...
  Gopalakrishnan, M., Buckner, S.A., Whiteaker, K.L., Shieh, C., Molinari, E.J., Milicic, I., Daza, A.V., Davis-Taber, R., Scott, V.E., Sellers, D., Chess-Williams, R., ...> ;J Pharmacol Exp Ther. 2002 Oct
• (-)-(9S)-9-(3-Bromo-4-fluorophenyl)-2,3,5,6,7,9-hexahydrothieno[3,2-b]quinolin-8(4H)-one 1,1-dioxide (A-278637): a novel ATP-sensitive potassium channel opener efficac...
  Brune, M.E., Fey, T.A., Brioni, J.D., Sullivan, J.P., Williams, M., Carroll, W.A., Coghlan, M.J., Gopalakrishnan, M.> ;J Pharmacol Exp Ther. 2002 Oct
• P2X7-related modulation of pathological nociception in rats.
  McGaraughty, S., Chu, K. L., Namovic, M. T., Donnelly-Roberts, D. L., Harris, R. R., Zhang, X. F., Shieh, C. C., Wismer, C. T., Zhu, C. Z., Gauvin, D. M., Fabiyi, A. C...> ;Neuroscience. 2007 Jun 8
• Structure-activity studies for a novel series of tricyclic substituted hexahydrobenz[e]isoindole alpha(1A) adrenoceptor antagonists as potential agents for the symptom...
  Meyer, M. D., Altenbach, R. J., Basha, F. Z., Carroll, W. A., Condon, S., Elmore, S. W., Kerwin, J. F., Sippy, K. B., Tietje, K., Wendt, M. D., Hancock, A. A., Brune, ...> ;J Med Chem. 2000 Apr 20
• Synthesis and pharmacological characterization of 3-[2-((3aR,9bR)-cis-6-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benz[e] isoindol-2-yl)ethyl]pyrido-[3',4':4,5]thieno[3,2-d]p...
  Meyer, M. D., Altenbach, R. J., Basha, F. Z., Carroll, W. A., Drizin, I., Elmore, S. W., Ehrlich, P. P., Lebold, S. A., Tietje, K., Sippy, K. B., Wendt, M. D., Plata, ...> ;J Med Chem. 1997 Sep 26
• Characterization of a novel ATP-sensitive K+ channel opener, A-251179, on urinary bladder relaxation and cystometric parameters.
  Shieh, C. C., Brune, M. E., Buckner, S. A., Whiteaker, K. L., Molinari, E. J., Milicic, I. A., Fabiyi, A. C., Daza, A., Brioni, J. D., Carroll, W. A., Matsushita, K., ...> ;Br J Pharmacol. 2007 Jun
• Structure-activity studies for a novel series of N-(arylethyl)-N-(1,2,3,4-tetrahydronaphthalen-1-ylmethyl)-N-methylamine s possessing dual 5-HT uptake inhibiting and a...
  Meyer, M. D., Hancock, A. A., Tietje, K., Sippy, K. B., Prasad, R., Stout, D. M., Arendsen, D. L., Donner, B. G., Carroll, W. A.> ;J Med Chem. 1997 Mar 28
• Structure-activity studies for a novel series of bicyclic substituted hexahydrobenz[e]isoindole alpha1A adrenoceptor antagonists as potential agents for the symptomati...
  Meyer, M. D., Altenbach, R. J., Bai, H., Basha, F. Z., Carroll, W. A., Kerwin, J. F., Lebold, S. A., Lee, E., Pratt, J. K., Sippy, K. B., Tietje, K., Wendt, M. D., Bru...> ;J Med Chem. 2001 Jun 7
• Recent developments in the biology and medicinal chemistry of potassium channel modulators: update from a decade of progress.
  Coghlan, M. J., Carroll, W. A., Gopalakrishnan, M.> ;J Med Chem. 2001 May 24
• Two novel and potent 3-[(o-methoxyphenyl)piperazinylethyl]-5-phenylthien.
  Carroll, W. A., Sippy, K. B., Esbenshade, T. A., Buckner, S. A., Hancock, A. A., Meyer, M. D.> ;Bioorg Med Chem Lett. 2001 May 7
• The discovery of a new class of large-conductance Ca2+-activated K+ channel opener targeted for overactive bladder: synthesis and structure-activity relationships of 2...
  Turner, S. C., Carroll, W. A., White, T. K., Gopalakrishnan, M., Coghlan, M. J., Shieh, C. C., Zhang, X. F., Parihar, A. S., Buckner, S. A., Milicic, I., Sullivan, J. P.> ;Bioorg Med Chem Lett. 2003 Jun 16
• Structure-activity relationship of a novel class of naphthyl amide KATP channel openers.
  Turner, S. C., Carroll, W. A., White, T. K., Brune, M. E., Buckner, S. A., Gopalakrishnan, M., Fabiyi, A., Coghlan, M. J., Scott, V. E., Castle, N. A., Daza, A. V., Mi...> ;Bioorg Med Chem Lett. 2003 May 19
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