WilliamHarvardFlemingMD

PubMed

• 31 citations
  MYC Promotes Bone Marrow Stem Cell Dysfunction in Fanconi Anemia.
  Alfredo E. Rodriguez, Kaiyang Zhang, Anniina Färkkilä, Jessica Filiatrault, Chunyu Yang, Martha Velázquez, Elissa Furutani, Devorah C. Goldman, Benilde García-de Teres...> ;Cell Stem Cell. 2021 Jan 7
• 9 citations
  Extrahepatic deficiency of transferrin receptor 2 is associated with increased erythropoiesis independent of iron overload.
  Aaron M. Wortham, Devorah C. Goldman, Juxjing Chen, William H. Fleming, An-Sheng Zhang, Caroline A. Enns> ;The Journal of Biological Chemistry. 2020 Mar 20
• 14 citations
  LMTK3 Is Essential for Oncogenic KIT Expression in KIT-mutant GIST and Melanoma
  Lillian R. Klug, Amber E Bannon, Nathalie Javidi-Sharifi, Ajia Town, William H. Fleming, Judy K. VanSlyke, Linda S. Musil, Jonathan A. Fletcher, Jeffrey W. Tyner, Mich...> ;Oncogene. 2019 Feb 1
• 13 citations
  The tumor suppressor phosphatase PP2A-B56α regulates stemness and promotes the initiation of malignancies in a novel murine model.
  Mahnaz Janghorban, Ellen M. Langer, Xiaoyan Wang, Derek Zachman, Colin J. Daniel, Jody E. Hooper, William H. Fleming, Anupriya Agarwal, Rosalie C. Sears> ;Plos One. 2017 Nov 30
• 13 citations
  The Corepressor Rcor1 Is Essential for Normal Myeloerythroid Lineage Differentiation
  Huilan Yao, Devorah C. Goldman, Guang Fan, Gail Mandel, William H. Fleming> ;Stem Cells. 2015 Nov 1
• 11 citations
  The triterpenoid RTA 408 is a robust mitigator of hematopoietic acute radiation syndrome in mice.
  Devorah C. Goldman, Vitali Alexeev, Elizabeth Lash, Chandan Guha, Ulrich Rodeck, William H. Fleming> ;Radiation Research. 2015 Mar 4
• 42 citations
  Intestinal Microbiota-Derived Metabolomic Blood Plasma Markers for Prior Radiation Injury
  Pilib Ó Broin, Bhavapriya Vaitheesvaran, Subhrajit Saha, Kirsten Hartil, Emily I. Chen, Devorah C. Goldman, William H. Fleming, Irwin J. Kurland, Chandan Guha, Aaron G...> ;International Journal of Radiation Oncology, Biology, Physics. 2015 Feb 1
• 65 citations
  Functional integration of acute myeloid leukemia into the vascular niche.
  Christopher R. Cogle, Devorah C. Goldman, Gerard J. Madlambayan, Ronald P. Leon, Azzah Al Masri, Hilary A. Clark, Steven A. Asbaghi, Jeffrey W. Tyner, Jennifer Dunlap,...> ;Leukemia. 2014 Mar 18
• 20 citations
  Corepressor Rcor1 is essential for murine erythropoiesis
  Huilan Yao, Devorah C. Goldman, Tamilla Nechiporuk, Sunita Kawane, Shannon K. McWeeney, Jeffrey W. Tyner, Guang Fan, Marc A. Kerenyi, Stuart H. Orkin, William H. Flemi...> ;Blood. 2014 May 15
• 30 citations
  HCMV infection of humanized mice after transplantation of G-CSF-mobilized peripheral blood stem cells from HCMV-seropositive donors.
  Morgan Hakki, Devorah C. Goldman, Daniel N. Streblow, Kimberly L. Hamlin, Craig N. Krekylwich, William H. Fleming, Jay A. Nelson> ;Biology of Blood and Marrow Transplantation. 2014 Jan 1
• 12 citations
  Endothelial cells mitigate DNA damage and promote the regeneration of hematopoietic stem cells after radiation injury
  Derek Zachman, Ronald P. Leon, Prerna Das, Devorah C. Goldman, Kimberly L. Hamlin, Chandan Guha, William H. Fleming> ;Stem Cell Research. 2013 Nov 1
• 119 citations
  Kinase Pathway Dependence in Primary Human Leukemias Determined by Rapid Inhibitor Screening
  Jeffrey W. Tyner, Wayne F. Yang, Armand Bankhead, Guang Fan, Luke B Fletcher, Jade Bryant, Jason M. Glover, Bill H. Chang, Stephen E. Spurgeon, William H. Fleming, Tib...> ;Cancer Research. 2013 Jan 1
• 14 citations
  Multiplex high-throughput gene mutation analysis in acute myeloid leukemia.
  Jennifer Dunlap, Carol Beadling, Andrea Warrick, Tanaya Neff, William H. Fleming, Marc M. Loriaux, Michael Heinrich, Tibor Kovacsovics, Katalin Kelemen, Nicky Leeborg,...> ;Human Pathology. 2012 Dec 1
• 120 citations
  A Novel Human Cytomegalovirus Locus Modulates Cell Type-Specific Outcomes of Infection
  Mahadevaiah Umashankar, Alex Petrucelli, Louis Cicchini, Patrizia Caposio, Craig N. Kreklywich, Michael Rak, Farah Bughio, Devorah C. Goldman, Kimberly L. Hamlin, Jay ...> ;Plos Pathogens. 2011 Dec 29
• High-throughput mutation analysis in acute myeloid leukemia (AML).
  Dunlap J, Corless CL, Fleming WH, Braziel R, Leeborg N, Gatter K, Loriaux M, Kelemen K, Kovacsovics T, Fan G> ;J. Clin. Oncol.. 2011-05-20
• 70 citations
  Fancd2−/− mice have hematopoietic defects that can be partially corrected by resveratrol
  Qing Shuo Zhang, Laura Marquez-Loza, Laura Eaton, Andrew W. Duncan, Devorah C. Goldman, Praveen Anur, Kevin Watanabe-Smith, R. Keaney Rathbun, William H. Fleming, Grov...> ;Blood. 2010 Dec 9
• 101 citations
  Granulocyte-Colony Stimulating Factor Reactivates Human Cytomegalovirus in a Latently Infected Humanized Mouse Model
  M. Shane Smith, Devorah C. Goldman, Alexis S. Bailey, Dana L. Pfaffle, Craig N. Kreklywich, Doran B. Spencer, Florence A. Othieno, Daniel N. Streblow, J. Victor Garcia...> ;Cell Host & Microbe. 2010 Sep 16
• 34 citations
  Endothelial cells mediate the regeneration of hematopoietic stem cells
  Bei Li, Alexis S. Bailey, Shuguang Jiang, Bin Liu, Devorah C. Goldman, William H. Fleming> ;Stem Cell Research. 2010 Jan 1
• 82 citations
  BMP4 regulates the hematopoietic stem cell niche.
  Devorah C. Goldman, Alexis S. Bailey, Dana L. Pfaffle, Azzah Al Masri, Jan L. Christian, William H. Fleming> ;Blood. 2009 Nov 12
• 42 citations
  Apoptosis-stimulating protein of p53 (ASPP2) heterozygous mice are tumor-prone and have attenuated cellular damage–response thresholds
  Kerstin M. Kampa, Jared D. Acoba, Dexi Chen, Hunjoo Lee, Kelly Beemer, Emerson Padiernos, Nataya W. Boonmark, Zhiyi Zhu, Alice C. Fan, Alexis S. Bailey, William H. Fle...> ;Proceedings of the National Academy of Sciences of the United States of America. 2009 Mar 17
• 25 citations
  Transvection mediated by the translocated cyclin D1 locus in mantle cell lymphoma
  Hui Liu, Jing Huang, Jin Wang, Shuguang Jiang, Alexis S. Bailey, Devorah C. Goldman, Markus Welcker, Victoria Bedell, Marilyn L. Slovak, Bruce E. Clurman, Mathew J. Th...> ;The Journal of Experimental Medicine. 2008 Aug 4
• 56 citations
  Hematopoietic stem cells contribute to lymphatic endothelium.
  Shuguang Jiang, Alexis S. Bailey, Devorah C. Goldman, John R. Swain, Melissa H. Wong, Philip R. Streeter, William H. Fleming> ;Plos One. 2008 Nov 26
• 13 citations
  Mouse models of hematopoietic engraftment: limitations of transgenic green fluorescent protein strains and a high-performance liquid chromatography approach to analysi...
  Gerald J. Spangrude, Scott Cho, Otto C. Guedelhoefer, Ryan C. Vanwoerkom, William H. Fleming> ;Stem Cells. 2006 Sep 1
• 160 citations
  Myeloid lineage progenitors give rise to vascular endothelium
  Alexis S. Bailey, Holger Willenbring, Shuguang Jiang, Daniel A. Anderson, David A. Schroeder, Melissa H. Wong, Markus Grompe, William H. Fleming> ;Proceedings of the National Academy of Sciences of the United States of America. 2006 Aug 29
• 194 citations
  Bone marrow-derived cells fuse with normal and transformed intestinal stem cells
  Adnan Z. Rizvi, John R. Swain, Paige S. Davies, Alexis S. Bailey, Adria D. Decker, Holger Willenbring, Markus Grompe, William H. Fleming, Melissa H. Wong> ;Proceedings of the National Academy of Sciences of the United States of America. 2006 Apr 18
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Journal Articles

• LMTK3 Is Essential for Oncogenic KIT Expression in KIT-Mutant GIST and Melanoma  
  Jonathan A Fletcher, William H Fleming, Nature