WilliamEGillandersMD

Breast, Endocrine, Surgical Oncology (Other than Breast)

Professor, Surgery, Washington University School of Medicine

Overview of Dr. Gillanders

Dr. William Gillanders, MD is a general surgeon in Saint Louis, Missouri. He is currently licensed to practice medicine in Missouri and South Carolina. He is affiliated with Barnes-Jewish Hospital, St. Louis Children's Hospital, and Siteman Cancer Center.

Office
4921 Parkview Pl
Ste 7C
Saint Louis, MO 63110
Book by Phone+1(314) 310-1560

Fax(314) 454-5509
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Education & Training

Washington University in St. Louis School of MedicineResidency, Surgery, 1991 - 1999
Duke University School of MedicineClass of 1991

Certifications & Licensure

MO State Medical License 2005 - 2023
SC State Medical License 1999 - 2005
American Board of Surgery Surgery

Awards, Honors, & Recognition

CMS Meaningful Use Stage 1 Certification Allscripts Enterprise EHR, Allscripts, 2012
Fellow (FACS) American College of Surgeons

Clinical Trials

Effect of Neoadjuvant or Adjuvant Systemic Therapy on Breast Cancers, Bone Marrow Cancer Cells, and Circulating Cancer Cells Start of enrollment: 2005 Sep 14
Recruiting
A Study to Determine the Clinical Significance of Molecular Detection of Breast Cancer in the Blood of Stage IV Breast Cancer Patients Start of enrollment: 2005 Nov 01
Completed
Not Applicable
LDE225 in Treating Patients With Stage II-III Estrogen Receptor- and HER2-Negative Breast Cancer Start of enrollment: 2014 Apr 01
Withdrawn
Phase 2
Effect of Trastuzumab on Disease Free Survival in Early Stage HER2-Negative Breast Cancer Patients With ERBB2 Expressing Disseminated Tumor Cells Start of enrollment: 2013 Dec 19
Terminated
Phase 2
Axillary Ultrasound With or Without Sentinel Lymph Node Biopsy in Detecting the Spread of Breast Cancer in Patients Receiving Breast Conservation Therapy Start of enrollment: 2013 Apr 04
Terminated
Not Applicable
Paclitaxel and BKM120 Before Surgery in Treating Patients With Stage II or III Estrogen Receptor-Positive and HER2-Negative Breast Cancer Start of enrollment: 2014 Aug 01
Withdrawn
Phase 2
Neoadjuvant Treatment of Triple Negative Breast Cancer Patients With Docetaxel and Carboplatin to Assess Anti-tumor Activity Start of enrollment: 2014 Jul 07
Terminated
Phase 2
Safety and Immune Response to a Mammaglobin-A DNA Vaccine In Breast Cancer Patients Undergoing Neoadjuvant Endocrine Therapy Start of enrollment: 2015 Jan 07
Recruiting
Phase 1
Safety and Immunogenicity of a Personalized Synthetic Long Peptide Breast Cancer Vaccine Strategy in Patients With Persistent Triple-Negative Breast Cancer Following Neoadjuvant Chemotherapy Start of enrollment: 2015 Sep 29
Withdrawn
Phase 1
Testing the Addition of an Individualized Vaccine to Nab-Paclitaxel, Durvalumab and Tremelimumab and Chemotherapy in Patients With Metastatic Triple Negative Breast Cancer Start of enrollment: 2018 Dec 14
Recruiting
Phase 2
Expanded Access Neoantigen Vaccine in Solid Tumors
Temporarily not available
Neoantigen Peptide Vaccine Strategy in Pancreatic Cancer Patients Following Surgical Resection and Adjuvant Chemotherapy Start of enrollment: 2020 Feb 13
Active, not recruiting
Phase 1
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Publications & Presentations

PubMed

4 citations
Neoadjuvant FOLFIRINOX Therapy Is Associated with Increased Effector T Cells and Reduced Suppressor Cells in Patients with Pancreatic Cancer.
Hui Peng, C. Alston James, Darren R. Cullinan, Graham D. Hogg, Jacqueline Mudd, Chong Zuo, Rony Takchi, Katharine E. Caldwell, Jingxia Liu, David G. DeNardo, Ryan C. F...> ;Clinical Cancer Research. 2021 Sep 30
Impact of consensus guidelines for breast-conserving surgery in patients with ductal carcinoma in situ
Abigail Tremelling, Rebecca Aft, Amy E. Cyr, William E. Gillanders, Katherine Glover-Collins, Virginia Herrmann, Julie A. Margenthaler> ;Cancer reports (Hoboken, N.J.). 2021 Jul 10
4 citations
Functional Implications of the Dynamic Regulation of EpCAM during Epithelial-to-Mesenchymal Transition.
Taylor C. Brown, Narendra V. Sankpal, William E. Gillanders> ;Biomolecules. 2021 Jun 29
6 citations
Immunogenomic profiling and pathological response results from a clinical trial of docetaxel and carboplatin in triple-negative breast cancer
Foluso O. Ademuyiwa, Ina Chen, Jingqin Luo, Mothaffar F. Rimawi, Ian S. Hagemann, Bryan Fisk, Gejae Jeffers, Zachary L. Skidmore, Anamika Basu, Megan Richters, Cynthia...> ;Breast Cancer Research and Treatment. 2021 Jun 26
1 citations
Cancer-associated mutations reveal a novel role for EpCAM as an inhibitor of cathepsin-L and tumor cell invasion
Narendra V. Sankpal, Taylor C. Brown, Timothy P. Fleming, John M. Herndon, Anusha A. Amaravati, Allison N. Loynd, William E. Gillanders> ;BMC Cancer. 2021 May 12
4 citations
Optimized polyepitope neoantigen DNA vaccines elicit neoantigen-specific immune responses in preclinical models and in clinical translation.
Lijin Li, Xiuli Zhang, Xiaoli Wang, Samuel W. Kim, John M. Herndon, Michelle Becker-Hapak, Beatriz M. Carreno, Nancy B. Myers, Mark A. Sturmoski, Michael D. McLellan, ...> ;Genome Medicine. 2021 Apr 21
3 citations
Neoantigen vaccine platforms in clinical development: understanding the future of personalized immunotherapy.
Suangson Supabphol, Lijin Li, S. Peter Goedegebuure, William E. Gillanders> ;Expert Opinion on Investigational Drugs. 2021 Mar 31
6 citations
Cancer vaccines: shared tumor antigens return to the spotlight.
Lijin Li, S. Peter Goedegebuure, William E. Gillanders> ;Signal Transduction and Targeted Therapy. 2020 Oct 30
86 citations
cDC1 prime and are licensed by CD4+ T cells to induce anti-tumour immunity
Stephen T. Ferris, Vivek Durai, Renee Wu, Derek J. Theisen, Jeffrey P. Ward, Michael D. Bern, Jesse T. Davidson, Prachi Bagadia, Tiantian Liu, Carlos G. Briseño, Lijin...> ;Nature. 2020 Aug 12
2 citations
Cost-effectiveness analyses demonstrate that observation is superior to sentinel lymph node biopsy for postmenopausal women with HR + breast cancer and negative axilla...
Aubriana M. McEvoy, Steven P. Poplack, Katelin B. Nickel, Margaret A. Olsen, Foluso O. Ademuyiwa, Imran Zoberi, Elizabeth B. Odom, Jennifer Yu, Su-Hsin Chang, William ...> ;Breast Cancer Research and Treatment. 2020 Jul 10
116 citations
The Human Tumor Atlas Network: Charting Tumor Transitions Across Space and Time at Single-Cell Resolution
Orit Rozenblatt-Rosen, Aviv Regev, Philipp Oberdoerffer, Tal Nawy, Anna Hupalowska, Jennifer Rood, Orr Ashenberg, Ethan Cerami, Robert J. Coffey, Emek Demir, Li Ding, ...> ;Cell. 2020 Apr 16
39 citations
pVACtools: A Computational Toolkit to Identify and Visualize Cancer Neoantigens.
Jasreet Hundal, Susanna Kiwala, Joshua F. McMichael, Christopher A. Miller, Huiming Xia, Alexander T. Wollam, Connor J. Liu, Sidi Zhao, Yang-Yang Feng, Aaron P. Graube...> ;Cancer immunology research. 2020 Jan 6
67 citations
Best practices for bioinformatic characterization of neoantigens for clinical utility
Megan Richters, Huiming Xia, Katie M. Campbell, William E. Gillanders, Obi L. Griffith, Malachi Griffith> ;Genome Medicine. 2019 Aug 28
21 citations
Precision delivery of RAS-inhibiting siRNA to KRAS driven cancer via peptide-based nanoparticles.
Matthew S. Strand, Bradley A. Krasnick, Hua Pan, Xiuli Zhang, Ye Bi, Candace Brooks, Christopher Wetzel, Narendra V. Sankpal, Timothy Fleming, S. Peter Goedegebuure, D...> ;Oncotarget. 2019 Jul 30
31 citations
Detection of neoantigen-specific T cells following a personalized vaccine in a patient with glioblastoma
Tanner M. Johanns, Christopher A. Miller, Connor J. Liu, Richard J. Perrin, Diane Bender, Dale K. Kobayashi, Jian L. Campian, Michael R. Chicoine, Ralph G. Dacey, Jiay...> ;OncoImmunology. 2019 Jan 25
100 citations
WDFY4 is required for cross-presentation in response to viral and tumor antigens
Derek J. Theisen, Jesse T. Davidson, Carlos G. Briseño, Marco Gargaro, Elvin J. Lauron, Qiuling Wang, Pritesh Desai, Vivek Durai, Prachi Bagadia, Joshua R. Brickner, W...> ;Science. 2018 Nov 9
197 citations
Targeting both tumour-associated CXCR2+ neutrophils and CCR2+ macrophages disrupts myeloid recruitment and improves chemotherapeutic responses in pancreatic ductal ade...
Timothy M. Nywening, Brian A. Belt, Darren R. Cullinan, Roheena Z. Panni, Booyeon J. Han, Dominic E. Sanford, Ryan C Jacobs, Jian Ye, Ankit A Patel, William E. Gilland...> ;Gut. 2018 Jun 1
20 citations
Development of an adenovirus vector vaccine platform for targeting dendritic cells
Piyush Kumar Sharma, Igor P. Dmitriev, Elena A. Kashentseva, Geert Raes, Lijin Li, Samuel W. Kim, Zhi Hong Lu, Jeffrey M. Arbeit, Timothy P. Fleming, Sergey A. Kaliber...> ;Cancer Gene Therapy. 2018 Feb 1
98 citations
Preclinical and clinical development of neoantigen vaccines
Lijin Li, Simon P. Goedegebuure, William E. Gillanders> ;Annals of Oncology. 2017 Dec 1
16 citations
Cost Analysis of a Surgical Consensus Guideline in Breast-Conserving Surgery
Jennifer Yu, Leisha C. Elmore, Amy E. Cyr, Rebecca Aft, William E. Gillanders, Julie A. Margenthaler> ;Journal of The American College of Surgeons. 2017 Aug 1
164 citations
NeoPalAna: Neoadjuvant Palbociclib, a Cyclin-Dependent Kinase 4/6 Inhibitor, and Anastrozole for Clinical Stage 2 or 3 Estrogen Receptor-Positive Breast Cancer.
Cynthia X. Ma, Feng Gao, Jingqin Luo, Donald W. Northfelt, Matthew P. Goetz, Andres Forero, Jeremy Hoog, Michael Naughton, Foluso O. Ademuyiwa, Rama Suresh, Karen S. A...> ;Clinical Cancer Research. 2017 Aug 1
38 citations
Breast Cancer Neoantigens Can Induce CD8 + T-Cell Responses and Antitumor Immunity
Xiuli Zhang, Samuel Kim, Jasreet Hundal, John M. Herndon, Shunqiang Li, Allegra A. Petti, Savas D. Soysal, Lijin Li, Michael D. McLellan, Jeremy Hoog, Tina Primeau, Na...> ;Cancer immunology research. 2017 Jul 1
41 citations
Personalized cancer vaccines: Targeting the cancer mutanome.
Xiuli Zhang, Piyush Kumar Sharma, S. Peter Goedegebuure, William E. Gillanders> ;Vaccine. 2017 Feb 15
37 citations
A double-negative feedback loop between EpCAM and ERK contributes to the regulation of epithelial-mesenchymal transition in cancer.
Narendra V. Sankpal, Timothy P. Fleming, Piyush Kumar Sharma, Hannah J. Wiedner, William E. Gillanders> ;Oncogene. 2017 Feb 13
35 citations
Axillary Ultrasound Accurately Excludes Clinically Significant Lymph Node Disease in Patients With Early Stage Breast Cancer.
Natalia S Tucker, Amy E. Cyr, Foluso O. Ademuyiwa, Adel Tabchy, Krystl George, Piyush Kumar Sharma, Linda X. Jin, Souzan Sanati, Rebecca Aft, Feng Gao, Julie A. Margen...> ;Annals of Surgery. 2016 Dec 1
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Journal Articles

WDFY4 Is Required for Cross-Presentation in Response to Viral and Tumor Antigens
Herbert W Virgin, Kenneth M Murphy, William E Gillanders, Wayne Yokoyama, Science Magazine

Press Mentions

$10.4 Million Awarded for Pancreatic Cancer ResearchAugust 15th, 2016

Grant Support

Peripheral Blood Molecular Staging Of Breast CancerNational Cancer Institute2006–2010
Molecular Detection Of Breast Cancer In Peripheral BloodNational Cancer Institute2004–2006
Molecular Detection Of Breast Cancer In Peripheral BloodNational Cancer Institute2002–2004
Peptide Mediated Immunotherapy In TransplantationNational Institute Of Allergy And Infectious Diseases1994–1995

Professional Memberships

American Society of Clinical Oncology - ASCO
Member
American College of Surgeons - ACS
Member
American Association of Endocrine Surgeons
Member

Hospital Affiliations

Siteman Cancer CenterSaint Louis, Missouri
Barnes-Jewish HospitalSaint Louis, Missouri
St. Louis Children's HospitalSaint Louis, Missouri
Barnes-Jewish West County HospitalSaint Louis, Missouri

Insurance Accepted

Aetna Choice POS II
Aetna HMO
Anthem Blue Access Choice PPO
Anthem Blue Access PPO
Anthem Blue Preferred HMO
Anthem Blue Preferred Plus POS
Anthem Blue Preferred Select
BCBS Blue Card PPO
BCBS Illinois PPO
CIGNA HMO
CIGNA Open Access
CIGNA PPO
Coventry Health Care PPO Platinum
Coventry Missouri - HMO/POS
First Health PPO
Great West PPO
HealthLink PPO
Humana ChoiceCare Network PPO
Multiplan PHCS PPO
Multiplan PPO
United Healthcare - Direct Choice Plus POS
United Healthcare - Direct Options PPO
Please verify your coverage with the provider's office directly when scheduling an appointment