
William Mallory Grady MD
Gastrointestinal Cancer
Professor of Medicine
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1100 Fairview Ave N# 358080Seattle, WA 98109
Phone+1 206-667-1107
Fax+1 206-520-5620
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Summary
- I am a board certified internist and gastroenterologist. I have expertise in hereditary cancer syndromes and am Medical Director of the Seattle Cancer Care Alliance/University of Washington Gastrointestinal Cancer Prevention Clinic. I am also an NIH funded physician-scientist.
Education & Training
Case Western Reserve University/University Hospitals Cleveland Medical CenterFellowship, Gastroenterology, 1995 - 1997
University of MichiganFellowship, Gastroenterology, 1994 - 1995
University of WashingtonResidency, Internal Medicine, 1990 - 1994
University of Michigan Medical SchoolClass of 1990
Certifications & Licensure
WA State Medical License 1990 - 2027
TN State Medical License 1999 - 2005
OH State Medical License 1997 - 2001
MI State Medical License 1995 - 1996
American Board of Internal Medicine Internal Medicine
American Board of Internal Medicine Gastroenterology
Awards, Honors, & Recognition
- Elected Member The American Society for Clinical Investigation, 2009
- Fellow (AGAF) American Gastroenterological Association, 2009
Clinical Trials
- Genetic Determinants of Barrett's Esophagus and Esophageal Adenocarcinoma Start of enrollment: 2005 Oct 01
- ColoCare Study - Colorectal Cancer Cohort
Publications & Presentations
PubMed
- Histopathology-Based Spatial Profiling of Immune and Molecular Features Predicts Cancer Risk in Barrett's Esophagus Patients.Caner Ercan, Xiaoxi Pan, Thomas G Paulson, Matthew D Stachler, Fahire Göknur Akarca
Cancer Research. 2026-10-27 - Community assembly modeling of the microbiome within Barrett's esophagus and esophageal adenocarcinoma.Caitlin Guccione, Igor Sfiligoi, Antonio Gonzalez, Justin P Shaffer, Mariya Kazachkova
BMC Genomics. 2026-02-10 - 3 citationsEpigenetic Alterations in Colitis-Associated Colorectal Cancer.Nisha Ganesh, William M Grady, Andrew M Kaz
Epigenomes. 2026-01-16
Press Mentions
Could Simple Blood Tests Identify Cancer Earlier?October 17th, 2025
Mixed Results Seen for PREEMPT CRC Screening TestJune 4th, 2025
Blood Test for Cancer Screening Can Identify Adults with Colorectal CancerJune 2nd, 2025
Grant Support
- Computational 3D pathology for Barrett's esophagus risk stratificationSTANFORD UNIVERSITY2025–2029
- A 4D-tunable hydrogel for the study of the impact of the tumor microenvironment on the development of colorectal cancerUNIVERSITY OF WASHINGTON2024–2029
- Understanding adenoma progression: Interplay among tissue microenvironment, clonal architecture, and gut microbiomeFRED HUTCHINSON CANCER CENTER2022–2027
- Understanding adenoma progression: Interplay among tissue microenvironment, clonal architecture, and gut microbiomeFRED HUTCHINSON CANCER CENTER2022–2027
- Understanding adenoma progression: Interplay among tissue microenvironment, clonal architecture, and gut microbiomeFRED HUTCHINSON CANCER CENTER2022–2027
Committees
- Member, NCCN Colon Cancer Genetics Guidelines Steering Committee 2016 - 2019
Research History
- Professor of Medicine, Gastroenterology Division, University of Washington and Fred Hutchinson Cancer Research CenterNIH funded research program on the molecular pathogenesis of GI cancers and biomarkers for GI cancers with >100 publications to date2004 - 2019
Professional Memberships
- Fellow
Industry Relationships
- Advisory Board, Guardant HealthAdvisory Board2018 - 2019
- Advisory Board, FreenomeAdvisory Board2017 - 2019
- Advisory Board, SEngineAdvisory Board2016 - 2019
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