
William Mallory Grady MD
Gastrointestinal Cancer
Professor of Medicine
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1100 Fairview Ave N# 358080Seattle, WA 98109
Phone+1 206-667-1107
Fax+1 206-520-5620
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Summary
- I am a board certified internist and gastroenterologist. I have expertise in hereditary cancer syndromes and am Medical Director of the Seattle Cancer Care Alliance/University of Washington Gastrointestinal Cancer Prevention Clinic. I am also an NIH funded physician-scientist.
Education & Training
- Case Western Reserve University/University Hospitals Cleveland Medical CenterFellowship, Gastroenterology, 1995 - 1997
- University of MichiganFellowship, Gastroenterology, 1994 - 1995
- University of WashingtonResidency, Internal Medicine, 1990 - 1994
- University of Michigan Medical SchoolClass of 1990
Certifications & Licensure
- WA State Medical License 1990 - 2027
- TN State Medical License 1999 - 2005
- OH State Medical License 1997 - 2001
- MI State Medical License 1995 - 1996
- American Board of Internal Medicine Internal Medicine
- American Board of Internal Medicine Gastroenterology
Awards, Honors, & Recognition
- Elected Member The American Society for Clinical Investigation, 2009
- Fellow (AGAF) American Gastroenterological Association, 2009
Clinical Trials
- Genetic Determinants of Barrett's Esophagus and Esophageal Adenocarcinoma Start of enrollment: 2005 Oct 01
- ColoCare Study - Colorectal Cancer Cohort
Publications & Presentations
PubMed
- 1 citationsClinical Validation of a Circulating Tumor DNA-Based Blood Test to Screen for Colorectal Cancer.Aasma Shaukat, Carol A Burke, Andrew T Chan, William M Grady, Samir Gupta
JAMA. 2025-06-02 - Gastric Polyposis and Cancer in Western Patients With Familial Adenomatous Polyposis: Epidemiology, Detection, and Management.Arthur S Aelvoet, Evelien Dekker, Michael W Cruise, William M Grady, Gregory E Idos
Journal of the National Comprehensive Cancer Network. 2025-06-01 - Cost-effectiveness of blood-based colorectal cancer screening - a simulation model incorporating real-world longitudinal adherence.Elifnur Yay Donderici, Shaun P Forbes, Nicole J Zhang, Gregory Schafer, Victoria M Raymond
Expert Review of Pharmacoeconomics & Outcomes Research. 2025-06-01
Press Mentions
- Mixed Results Seen for PREEMPT CRC Screening TestJune 4th, 2025
- Blood Test for Cancer Screening Can Identify Adults with Colorectal CancerJune 2nd, 2025
- Colorectal Cancer Screening: Compliance Saves LivesMay 16th, 2025
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Grant Support
- A 4D-tunable hydrogel for the study of the impact of the tumor microenvironment on the development of colorectal cancerUNIVERSITY OF WASHINGTON2024–2029
- Computational 3D pathology for Barrett's esophagus risk stratificationUNIVERSITY OF WASHINGTON2024–2029
- Understanding adenoma progression: Interplay among tissue microenvironment, clonal architecture, and gut microbiomeFRED HUTCHINSON CANCER CENTER2022–2027
- Spatially Informed Malignancy Signatures for Colon AdenomasFRED HUTCHINSON CANCER CENTER2022–2027
- Spatially Informed Malignancy Signatures for Colon AdenomasFRED HUTCHINSON CANCER CENTER2022–2027
- Identifying Gut Microbial Inducers of Biological Aging in the ColonFRED HUTCHINSON CANCER CENTER2022–2027
- Spatially Informed Malignancy Signatures for Colon AdenomasFRED HUTCHINSON CANCER CENTER2022–2027
- Biomarkers for optimizing risk prediction and early detection of cancers of the colon and esophagusFRED HUTCHINSON CANCER CENTER2022–2027
- Understanding adenoma progression: Interplay among tissue microenvironment, clonal architecture, and gut microbiomeFRED HUTCHINSON CANCER CENTER2022–2027
- On-Demand Modulation of Extracellular Matrix Mechanics for Studying RhoA Activation in Primary and Metastatic Colorectal CancerUNIVERSITY OF WASHINGTON2024–2026
- The role of the senescent microenvironment on cancer initiating cells in the colon.FRED HUTCHINSON CANCER CENTER2021–2026
- The role of the senescent microenvironment on cancer initiating cells in the colon.FRED HUTCHINSON CANCER CENTER2021–2026
- Liver Cancer Disparities in Alaska Native and American Indian PeopleUNIVERSITY OF WASHINGTON2021–2025
- Genetic Determinants Of Barrett'S Esophagus And Esophageal AdenocarcinomaNational Cancer Institute2011
- Identify And Validate Novel Epigenetic Molecular Markers For Colorectal NeoplasmNational Cancer Institute2010–2011
- Human Tumor AnalysesNational Cancer Institute2009–2011
- Tgf-Beta Signaling And Colon CancerNational Cancer Institute2007–2011
- Effects Of Loss Of Tgf-Beta Rll In The LiverNational Institute Of Diabetes And Digestive And Kidney Diseases2004–2006
- Effects Of Loss Of Tgf-Beta Rll In The LiverNational Institute Of Diabetes And Digestive And Kidney Diseases2003
- TGF Beta Receptor Mutations And Human CancerNational Cancer Institute1999–2002
- TGF Beta Receptor Mutations And Human CancerNational Cancer Institute1998–1999
Committees
- Member, NCCN Colon Cancer Genetics Guidelines Steering Committee 2016 - 2019
Research History
- Professor of Medicine, Gastroenterology Division, University of Washington and Fred Hutchinson Cancer Research CenterNIH funded research program on the molecular pathogenesis of GI cancers and biomarkers for GI cancers with >100 publications to date2004 - 2019
Professional Memberships
- Fellow
Industry Relationships
- Advisory Board, Guardant HealthAdvisory Board2018 - 2019
- Advisory Board, FreenomeAdvisory Board2017 - 2019
- Advisory Board, SEngineAdvisory Board2016 - 2019
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