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William Lester, MD, Internal Medicine, Boston, MA

William Timothy Lester MD


Assistant Professor in Medicine, Massachusetts General Hospital, Harvard Medical School

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  • 15 Parkman StSte 625Boston, MA 02114

  • Phone+1 617-726-2375

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Summary

  • As a physician-engineer and clinical informatics executive at Massachusetts General Hospital and Harvard Medical School, I bring a unique, multidisciplinary perspective to healthcare transformation. For over 25 years, I have stood at the intersection of medicine, engineering, and health IT-turning complex clinical challenges into actionable, scalable solutions that drive real-world results.

    What sets me apart is the breadth and depth of my roles:
    • Practicing Clinician: I deliver primary and urgent care on the front lines, giving me firsthand understanding of the needs of patients and providers.
    • Engineering System Designer: My background in systems engineering enables me to architect robust, user-centered clinical information systems that truly work in practice.
    • Informatics Leader: I have led the design, implementation, and optimization of EMRs and decision support tools across diverse care settings, always with an eye toward measurable impact.

    Signature achievements:
    • Spearheaded the modernization of MGH’s Organ Transplantation EMR, launching advanced analytics and workflow platforms now adopted hospital-wide.
    • Advanced national standards for clinical quality measurement and published research that shapes the future of digital health.
    • Built and led high-performing, multidisciplinary teams, secured competitive grant funding, and mentored the next generation of informatics leaders.

    My passion lies in bridging clinical care and technology-creating data-driven, innovative solutions that improve outcomes, enhance efficiency, and empower healthcare teams. I am always eager to connect with those who share a vision for impactful health IT strategy, innovation, and leadership.

    Let’s connect and redefine what’s possible in healthcare together.

Education & Training

  • Mass General Brigham/Massachusetts General Hospital
    Mass General Brigham/Massachusetts General HospitalResidency, Internal Medicine, 1997 - 2000
  • McGovern Medical School at UTHealth
    McGovern Medical School at UTHealthClass of 1997
  • The University of Texas at Austin
    The University of Texas at AustinMS, Electrical and Biomedical Engineering, 1991 - 1993

Certifications & Licensure

  • MA State Medical License
    MA State Medical License 2000 - 2027
  • Internal Medicine
    American Board of Internal Medicine Internal Medicine

Clinical Trials

Publications & Presentations

PubMed

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