William E Luginbuhl MD

Oncology•Exton, PA

Medical Director Abramson Cancer Center West Chester

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720 W Lincoln HwySte 720Exton, PA 19341
Phone+1 610-269-8415
Fax+1 610-269-8419

Summary

I am a board certified hematologist and medical oncologist, interested in several areas including lung cancer, gynecologic oncology, general hematology including hematologic malignancies. I am involved in clinical research and serve as the principle investigator at our institution.

Education & Training

University of Pennsylvania Health SystemFellowship, Hematology and Medical Oncology, 1990 - 1993
University of FloridaResidency, Internal Medicine, 1987 - 1990
University of Vermont College of MedicineClass of 1987

Certifications & Licensure

PA State Medical License 1990 - 2026
FL State Medical License 1988 - 1991
American Board of Internal Medicine Medical Oncology

Clinical Trials

Chemotherapy With or Without Bevacizumab in Treating Patients With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma Start of enrollment: 2008 Aug 08
ACTIVE_NOT_RECRUITING
PHASE3
A Phase III Randomized Trial of Metformin vs Placebo in Early Stage Breast Cancer Start of enrollment: 2010 Aug 13
Completed
Phase 3
Tamoxifen Citrate, Letrozole, Anastrozole, or Exemestane With or Without Chemotherapy in Treating Patients With Invasive RxPONDER Breast Cancer Start of enrollment: 2011 Jan 15
ACTIVE_NOT_RECRUITING
PHASE3
Chemotherapy With or Without Trastuzumab After Surgery in Treating Women With Invasive Breast Cancer Start of enrollment: 2011 Jan 06
ACTIVE_NOT_RECRUITING
PHASE3
S0820, Adenoma and Second Primary Prevention Trial Start of enrollment: 2013 Aug 23
ACTIVE_NOT_RECRUITING
PHASE3
S1207 Hormone Therapy With or Without Everolimus in Treating Patients With Breast Cancer Start of enrollment: 2013 Sep 12
ACTIVE_NOT_RECRUITING
PHASE3
Rituximab and Bendamustine Hydrochloride, Rituximab and Ibrutinib, or Ibrutinib Alone in Treating Older Patients With Previously Untreated Chronic Lymphocytic Leukemia Start of enrollment: 2014 Jan 15
ACTIVE_NOT_RECRUITING
PHASE3
Ipilimumab With or Without Bevacizumab in Treating Patients With Stage III-IV Melanoma That Cannot Be Removed by Surgery Start of enrollment: 2014 Jan 24
ACTIVE_NOT_RECRUITING
PHASE2
Docetaxel, Carboplatin, Trastuzumab, and Pertuzumab With or Without Estrogen Deprivation in Treating Patients With Hormone Receptor-Positive, HER2-Positive Operable or Locally Advanced Breast Cancer Start of enrollment: 2014 Jan 15
ACTIVE_NOT_RECRUITING
PHASE3
S1403, Afatinib Dimaleate With or Without Cetuximab in Treating Patients With Newly Diagnosed Stage IV or Recurrent, EGFR Mutation Positive Non-small Cell Lung Cancer Start of enrollment: 2015 May 07
ACTIVE_NOT_RECRUITING
PHASE2, PHASE3
Doxorubicin Hydrochloride and Cyclophosphamide Followed by Paclitaxel With or Without Carboplatin in Treating Patients With Triple-Negative Breast Cancer Start of enrollment: 2015 Jul 26
Active, not recruiting
Phase 3
Lung-MAP: Taselisib as Therapy in Treating Patients With Stage IV Squamous Cell Lung Cancer and Positive Biomarker Matches Start of enrollment: 2014 Nov 01
Completed
Phase 2
Lung-MAP: Palbociclib as Second-Line Therapy in Treating Cell Cycle Gene Alteration Positive Patients With Recurrent Stage IV Squamous Cell Lung Cancer Start of enrollment: 2014 Sep 01
Completed
Phase 2, Phase 3
Lung-MAP: Nivolumab With or Without Ipilimumab as Second-Line Therapy in Treating Patients With Recurrent Stage IV Squamous Cell Lung Cancer and No Matching Biomarkers Start of enrollment: 2015 Dec 29
Active, not recruiting
Phase 3
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Publications & Presentations

PubMed

1 citations
A Cohort Study to Evaluate Genetic Predictors of Aromatase Inhibitor Musculoskeletal Symptoms: Results from ECOG-ACRIN E1Z11.
Vered Stearns, Opeyemi A Jegede, Victor T-S Chang, Todd C Skaar, Jeffrey L Berenberg
Clinical Cancer Research. 2024-07-01
1 citations
Isolated Ovarian Metastasis from Pancreatic Cancer Mimicking Primary Ovarian Neoplasia: Role of Molecular Analysis in Determining Diagnosis
Catherine M. Tucker, Cheryl L. Godcharles, Wei Jiang, Charles J. Yeo, Norman G. Rosenblum
Journal of Pancreatic Cancer. 2021-10-14
23 citations
Phase II Trial of All-Trans Retinoic Acid in Metastatic Non-Small Cell Lung Cancer
Joseph Treat, David Friedland, William E. Luginbuhl, Lorraine Meehan, Genevieve Gorman
Cancer Investigation. 1996-01-01

Research History

Chester County Cancer Center Principle Investigator2004 - Present

Professional Memberships

American College of Physicians - ACP
Member
American Society of Clinical Oncology - ASCO
Member