
William Jacob Mack IV MD
Cerebrovascular Neurosurgery, Interventional Neuroradiology
Professor, Neurological Surgery, USC School of Medicine
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1520 San Pablo StSte 3800Los Angeles, CA 90033
Phone+1 323-442-5720
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Summary
- Dr. William Mack is a neurosurgeon in Los Angeles, CA and is affiliated with multiple hospitals in the area, including Keck Hospital of USC, LAC+USC Medical Center, and Keck Hospital of USC. He received his medical degree from Columbia University College of Physicians & Surgeons and has been in practice 16 years. He specializes in cerebrovascular neurosurgery and interventional neuroradiology and is experienced in interventional neuroradiology / endovascular neurosurgery and cerebrovascular disease.
Education & Training
University of Southern CaliforniaMS, Clinical and Biomedical Investigation, 2011 - 2013
Ronald Reagan UCLA Medical CenterInterventional Neuroradiology, 2008 - 2010
New York Presbyterian Hospital (Cornell Campus)Residency, Neurological Surgery, 2002 - 2008
Columbia University Vagelos College of Physicians and SurgeonsClass of 2001
Certifications & Licensure
CA State Medical License 2008 - 2027
ME State Medical License 2023 - 2024
NY State Medical License 2004 - 2009
American Board of Neurological Surgery Neurological Surgery
Awards, Honors, & Recognition
- Fellow American College of Surgeons (FACS)
- CMS Meaningful Use Stage 2 Certification HealtheLife and PowerChart, Cerner Corporation, 2014, 2016-2017
- CMS Meaningful Use Stage 2 Certification PowerChart (All CQM's), Cerner Corporation, 2014, 2016-2017
Clinical Trials
- Endovascular Magnesium Sampling in Acute Stroke Start of enrollment: 2012 Mar 01
- Intra-arterial Magnesium Administration for Acute Stroke Start of enrollment: 2012 Mar 01
- TARGET Intracranial Aneurysm Coiling Registry Start of enrollment: 2013 Feb 01
Publications & Presentations
PubMed
- Association of cerebrovascular center volume with patient outcomes.Stacey Quintero Wolfe, Justin R Mascitelli, Kyle Fargen, Peter Kan, Ketan Bulsara
Neurosurgical Review. 2026-06-29 - 2 citationsMultidisciplinary Approach to Direct Segmental Artery Revascularization to Prevent Spinal Cord Ischemia Associated With Endovascular Thoracoabdominal Aortic Repair.Anand V Ganapathy, Alexander D DiBartolomeo, William J Mack, Gregory A Magee, Nadiya Atai
Journal of Endovascular Therapy. 2026-06-01 - Impact of intravenous thrombolysis on aspiration thrombectomy outcomes: an Imperative Trial subgroup analysis.Maxim Mokin, Reade Andrew De Leacy, William Mack, Raul G Nogueira, Shahram Majidi
Journal of Neurointerventional Surgery. 2026-05-12
Journal Articles
- Original Article Predictors of Venous Thromboembolism After Non-Emergent Craniotomy: A Nationwide Readmission Database AnalysisDaniel A Donoho, Ian A Buchanan, Frank Attenello, Arun P Amar, Steven L Giannotta, William J Mack, Michelle Lin, ScienceDirect
- Treatment at Safety-Net Hospitals Is Associated with Delays in Coil Embolization in Patients with Subarachnoid HemorrhageIan A Buchanan, Arun P Amar, William J Mack, World Neurosurgery
- Predictors of Surgical Site Infection After Non-Emergent Craniotomy: A Nationwide Readmission Database AnalysisIan A Buchanan, Steven L Giannotta, William J Mack, World Neurosurgery
Authored Content
- Predictors of Surgical Site Infection After Non-Emergent Craniotomy: A Nationwide Readmission Database AnalysisAugust 2018
Press Mentions
Imperative Care’s Zoom System Receives FDA ClearanceJanuary 27th, 2025
Imperative Care Announces Clinical Data from the Pivotal Imperative Trial Evaluating the Zoom Reperfusion System for the Treatment of Ischemic StrokeJuly 24th, 2024
Imperative Care’s Pivotal Trial of Zoom Reperfusion System PresentedJuly 24th, 2024
Professional Memberships
- Member
- Member
- Society of Neurointerventional SurgeonsMember
- Society of Neurological SurgeonsMember
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