WilliamWO'NeillMD

Cardiology • Troy, MI

Adult Congenital Heart Disease, Cardiac Electrophysiology, Interventional Cardiology

Physician

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Office
2825 Livernois Rd
Troy, MI 48083
Phone+1 313-916-2600

Fax+1 313-916-2819
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Education & Training

University of Michigan Health SystemFellowship, Cardiovascular Disease, 1980 - 1982
Wayne State University School of MedicineResidency, Internal Medicine, 1978 - 1980
University of Wisconsin Hospitals and ClinicsInternship, Internal Medicine, 1977 - 1978
Wayne State University School of MedicineClass of 1977

Certifications & Licensure

MI State Medical License 1978 - 2025
FL State Medical License 2006 - 2019
American Board of Internal Medicine Internal Medicine
American Board of Internal Medicine Cardiovascular Disease

Awards, Honors, & Recognition

CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2013

Clinical Trials

WATCH-TAVR, WATCHMAN for Patients With Atrial Fibrillation Undergoing Transcatheter Aortic Valve Replacement Start of enrollment: 2017 Dec 15
Completed
Not Applicable
National Cardiogenic Shock Initiative Start of enrollment: 2016 May 19
Completed
2019-06 TRISCEND Study Start of enrollment: 2020 May 06
Active, not recruiting
Not Applicable
Will Hydroxychloroquine Impede or Prevent COVID-19 Start of enrollment: 2020 Apr 07
Terminated
Phase 3
ACURATE IDE: Safety and Effectiveness Study of ACURATE Valve for Transcatheter Aortic Valve Replacement Start of enrollment: 2019 Jun 10
Recruiting
Not Applicable
Roles: Contact, Principal Investigator
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Publications & Presentations

PubMed

2 citations
Comparison of a new bioprosthetic mitral valve to other commercially available devices under controlled conditions in a porcine model.
Dee Dee Wang, Thomas G. Caranasos, Brian P. O'Neill, Richard S. Stack, William W. O'Neill, W. Randolph Chitwood> ;Journal of Cardiac Surgery. 2021 Dec 1
Comparative differences of mitral valve-in-valve implantation: A new mitral bioprosthesis versus current mosaic and epic valves.
Dee Dee Wang, Brian P. O'Neill, Thomas G. Caranasos, W. Randolph Chitwood, Richard S. Stack, William W. O'Neill> ;Catheterization and Cardiovascular Interventions. 2021 Nov 29
7 citations
Impella mechanical circulatory support for Takotsubo syndrome with shock: A retrospective multicenter analysis
L. Christian Napp, Ralf Westenfeld, Jacob E. Møller, Federico Pappalardo, Karim Ibrahim, Laurent Bonello, Charles Wilkins, Ashish Pershad, Salvatore F. Mannino, Theodo...> ;Cardiovascular Revascularization Medicine. 2021 Nov 19
21 citations
Risk Prediction in Cardiogenic Shock: Current State of Knowledge, Challenges and Opportunities.
Sanjog Kalra, Lauren S. Ranard, Sehrish Memon, Prashant Rao, A. Reshad Garan, Amirali Masoumi, William W. O'Neill, Navin K. Kapur, Dimitri Karmpaliotis, Justin Fried, ...> ;Journal of Cardiac Failure. 2021 Oct 1
2 citations
Alternative Access for Transcatheter Aortic Valve Replacement: A Comprehensive Review.
Marvin H. Eng, Mohammed Qintar, Dmitrios Apostolou, William W. O'Neill> ;Interventional Cardiology Clinics. 2021 Oct 1
8 citations
Predictors of Left Ventricular Outflow Tract Obstruction After Transcatheter Mitral Valve Replacement in Severe Mitral Annular Calcification: An Analysis of the Transc...
Abdallah El Sabbagh, Mohammed Al-Hijji, Dee Dee Wang, Mackram F. Eleid, Marina Urena, Dominique Himbert, Tarun Chakravarty, David Holzhey, Ashish Pershad, H. Kenith Fa...> ;Circulation. Cardiovascular Interventions. 2021 Oct 1
Cardiogenic Shock Management Should Be a Team Sport.
Perwaiz Meraj, William W. O'Neill> ;Journal of the American College of Cardiology. 2021 Sep 28
Initial in-human experience with the conveyor cardiovascular system for the delivery of large profile transcatheter valve devices.
Brian P. O'Neill, Dee Dee Wang, Thomas G. Caranasos, W. Randolph Chitwood, William W. O'Neill, Richard S. Stack> ;Catheterization and Cardiovascular Interventions. 2021 Sep 17
12 citations
Additive Value of Preprocedural Computed Tomography Planning Versus Stand‐Alone Transesophageal Echocardiogram Guidance to Left Atrial Appendage Occlusion: Comparison ...
Chak-Yu So, Guson Kang, Pedro A. Villablanca, Abel Ignatius, Saleha Asghar, Dilshan Dhillon, James Lee, Arfaat Khan, Gurjit Singh, Tiberio Frisoli, Brian P O'Neill, Ma...> ;Journal of the American Heart Association. 2021 Sep 7
8 citations
Vitamin D levels and mortality with SARS-COV-2 infection: a retrospective two-centre cohort study.
Mansoor Zafar, Mangala Karkhanis, Muhammad Shahbaz, Alisha Khanna, Lucinda Barry, Saba Alam, Kamal Lawrence, Bipin Pun, Reem Eldebri, O. A. Makanjuola, Dana Safarova, ...> ;Postgraduate Medical Journal. 2021 Sep 6
3 citations
Vacuum to the Rescue: Aspiration of a Large Mobile Aortic Arch Thrombus With the AngioVac System Utilizing Transcaval Access.
Mohammed Qintar, Dee Dee Wang, William W. O'Neill, Brian P. O'Neill> ;The Journal of Invasive Cardiology. 2021 Sep 1
25 citations
Vasopressors independently associated with mortality in acute myocardial infarction and cardiogenic shock.
Mir B Basir, Alejandro Lemor, Sarah Gorgis, Angela M. Taylor, Behnam Tehrani, Alexander G. Truesdell, Aditya Bharadwaj, Brian Kolski, Kirit Patel, Joseph Gelormini, Jo...> ;Catheterization and Cardiovascular Interventions. 2021 Aug 3
1 citations
Incidence of acquired ventricular septal defect after transcatheter aortic valve replacement: A large single center experience
Paul Nona, Shazil Mahmood, Alejandro Lemor, Mohammed Qintar, Brian P O'Neill, James Lee, Tiberio Frisoli, Dee Dee Wang, Marvin H. Eng, William W. O'Neill, Pedro A. Vil...> ;Catheterization and Cardiovascular Interventions. 2021 Aug 3
Left Atrial Appendage Occlusion With the LAmbre Device: First-in-Human in the United States.
Mohammed Qintar, Dee Dee Wang, James R. Lee, Marvin H. Eng, Tiberio Frisoli, Pedro A. Villablanca, William W. O'Neill, Brian P. O'Neill> ;The Journal of Invasive Cardiology. 2021 Aug 1
5 citations
Trends in the Outcomes of High-risk Percutaneous Ventricular Assist Device-assisted Percutaneous Coronary Intervention, 2008-2018.
Alejandro Lemor, Mir B Basir, Alexander G. Truesdell, Jacqueline E. Tamis-Holland, Mohammad Alqarqaz, Cindy L. Grines, Pedro A. Villablanca, Khaldoon Alaswad, Duane S....> ;The American Journal of Cardiology. 2021 Jul 31
91 citations
Predictors of Device-Related Thrombus Following Percutaneous Left Atrial Appendage Occlusion
Trevor Simard, Richard G. Jung, Kyle Lehenbauer, Kerstin Piayda, Radosław Pracoń, Gregory G. Jackson, Eduardo Flores-Umanzor, Laurent Faroux, Kasper Korsholm, Julian K...> ;Journal of the American College of Cardiology. 2021 Jul 27
71 citations
Phenotyping Cardiogenic Shock.
Elric Zweck, Katherine L. Thayer, Ole Kristian Lerche Helgestad, Manreet Kanwar, Mohyee Ayouty, A. Reshad Garan, Jaime Hernandez-Montfort, Claudius Mahr, Detlef Wencke...> ;Journal of the American Heart Association. 2021 Jul 20
8 citations
Short- and mid-term outcomes in percutaneous mitral valve replacement using balloon expandable valves
Marvin H. Eng, Faraj Kargoli, Dee Dee Wang, Tiberio Frisoli, James Lee, Pedro S. Villablanca, Hassan Nemeh, Adam Greenbaum, Mayra Guerrero, Brian P O'Neill, Janet Wyma...> ;Catheterization and Cardiovascular Interventions. 2021 Jun 9
1 citations
Emergency Alcohol Septal Ablation for Shock After TAVR: One More Option in the Toolbox.
Mohammed Qintar, Pedro A. Villablanca, James Lee, Dee Dee Wang, Tiberio Frisoli, Brian P O'Neill, Marvin H. Eng, William W. O'Neill> ;JACC. Case Reports. 2021 Jun 1
4 citations
Outcomes of bailout percutaneous ventricular assist device versus prophylactic strategy in patients undergoing nonemergent percutaneous coronary intervention.
Brian P. O'Neill, Cindy L. Grines, Jeffrey W. Moses, E. Magnus Ohman, Alexandra J. Lansky, J.J. Popma, Navin K. Kapur, Theodore Schreiber, Salvatore F. Mannino, Willia...> ;Catheterization and Cardiovascular Interventions. 2021 May 29
Re-instituting a live cardiology meeting without symptomatic COVID-19 transmission.
David G. Rizik, Sunil V. Rao, Gregg W. Stone, Robert F. Burke, James B. Hermiller, William W. O'Neill> ;Catheterization and Cardiovascular Interventions. 2021 May 13
5 citations
Real world outcomes using 20 mm balloon expandable SAPIEN 3/ultra valves compared to larger valves (23, 26, and 29 mm)-a propensity matched analysis.
Marvin H. Eng, Amr E. Abbas, Rebecca T. Hahn, James Lee, Dee Dee Wang, Mackram F. Eleid, William W. O'Neill> ;Catheterization and Cardiovascular Interventions. 2021 May 13
5 citations
Reviving Invasive Hemodynamic Monitoring in Cardiogenic Shock. Invasive Hemodynamic Monitoring in Cardiogenic Shock
Mohammed Osman, Sudarshan Balla, Allison Dupont, William W. O'Neill, Mir B Basir> ;The American Journal of Cardiology. 2021 May 7
2 citations
Patent foramen ovale closure with vena cava thrombus: You need an arm and a neck!
Mohammed Qintar, Pedro A. Villablanca, James Lee, Dee Dee Wang, Tiberio Frisoli, Brian P. O'Neill, William W. O'Neill, Marvin H. Eng> ;Clinical Case Reports. 2021 May 1
37 citations
Prospective Evaluation of Transseptal TMVR for Failed Surgical Bioprostheses: MITRAL Trial Valve-in-Valve Arm 1-Year Outcomes
, , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , > ;JACC. Cardiovascular Interventions. 2021 Apr 26
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Lectures

Current Landscape and Future Directions: Percutaneous Ventricular Assist Devices
CRF Transcatheter Cardiovascular Therapeutics - Annual Symposium 2019 - Miami, FL - 9/25/2019
Personal Position Statement: “All Patients With Cardiogenic Shock Should Receive Advanced Mechanical Circulatory Support
2019 ACC Scientific Session & Expo, New Orleans - 3/16/2019

Press Mentions

Abiomed at CRT 2023: Benefits of Impella-Supported High Risk PCI and Impella InnovationFebruary 24th, 2023
Abiomed Impella–Supported PCI in High-Risk Patients Studied in Restore EFAugust 16th, 2022
COVID-19: Study Shows Virus Can Infect Heart Cells in Lab DishJune 30th, 2020
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