WilliamFrancisPennyMD

Cardiology • San Diego, CA

Adult Congenital Heart Disease, Interventional Cardiology

Professor, Medicine, UCSD School of Medicine

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Office
3350 La Jolla Village Dr
San Diego, CA 92161
Phone+1 858-642-3975

Fax+1 858-552-7490
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Education & Training

Beth Israel Deaconess Medical Center/Harvard Medical SchoolFellowship, Cardiovascular Disease, 1987 - 1990
UCLA David Geffen School of Medicine/UCLA Medical CenterResidency, Internal Medicine, 1984 - 1987
Washington University in St. Louis School of MedicineClass of 1984

Certifications & Licensure

CA State Medical License 1985 - 2025
American Board of Internal Medicine Internal Medicine
American Board of Internal Medicine Cardiovascular Disease
American Board of Internal Medicine Interventional Cardiology

Clinical Trials

AC6 Gene Transfer for CHF Start of enrollment: 2010 Jul 01
Completed
Phase 1, Phase 2
Prevention of Serious Adverse Events Following Angiography Start of enrollment: 2013 Oct 07
Completed
Phase 3

Publications & Presentations

PubMed

10 citations
Peptidic Sulfhydryl for Interfacing Nanocrystals and Subsequent Sensing of SARS-CoV-2 Protease.
Zhicheng Jin, Justin Yeung, Jiajing Zhou, Yong Cheng, Yi Li, Yash Mantri, Tengyu He, Wonjun Yim, Ming Xu, Zhuohong Wu, Pavla Fajtova, Matthew N Creyer, Colman Moore, L...> ;Chemistry of Materials. 2022 Feb 8
7 citations
Enhanced Photoacoustic Detection of Heparin in Whole BloodMelanin Nanocapsules Carrying Molecular Agents.
Wonjun Yim, Kathryn Takemura, Jiajing Zhou, Jingcheng Zhou, Zhicheng Jin, Raina M Borum, Ming Xu, Yong Cheng, Tengyu He, William Penny, Bill R Miller 3rd, Jesse V Jokerst> ;ACS Nano. 2022 Jan 25
6 citations
A fiber optic photoacoustic sensor for real-time heparin monitoring
Jingcheng Zhou, Wonjun Yim, Jiajing Zhou, Zhicheng Jin, Ming Xu, Yash Mantri, Tengyu He, Yong Cheng, Lei Fu, Zhuohong Wu, Tiffany Hancock, William F. Penny, Jesse V. J...> ;Biosensors & Bioelectronics. 2022 Jan 15
10 citations
Mapping Aerosolized Saliva on Face Coverings for Biosensing Applications.
Zhicheng Jin, Alec Jorns, Wonjun Yim, Ryan Wing, Yash Mantri, Jiajing Zhou, Jingcheng Zhou, Zhuohong Wu, Colman Moore, William F. Penny, Jesse V. Jokerst> ;Analytical Chemistry. 2021 Aug 10
3 citations
Point-of-Care Ultrasound as a Tool to Assess Wound Size and Tissue Regeneration after Skin Grafting.
Yash Mantri, Jason Tsujimoto, William F. Penny, Pranav S. Garimella, Caesar A. Anderson, Jesse V. Jokerst> ;Ultrasound in Medicine & Biology. 2021 Jun 28
6 citations
Left internal mammary artery side branch intervention in the management of coronary steal syndrome following coronary artery bypass grafting.
Daniel Mangels, William F. Penny, Ryan Reeves> ;Catheterization and Cardiovascular Interventions. 2021 Jan 1
Diffuse saphenous vein graft thrombosis: resolution after one month of apixaban and dual antiplatelet therapy.
Stephen D. Dickson, Adam Taleb, Szymon Wiernek, Alayn Govea, William F. Penny> ;Coronary Artery Disease. 2020 Dec 1
Evaluation of a Novel Antiplatelet Therapy Strategy in Patients Undergoing Elective Percutaneous Coronary Intervention
Kayla Giang, Holly E Stallings, Paul Clopton, Maria K Stubbs, William F. Penny> ;Journal of Pharmacy Practice. 2021 Dec 1
7 citations
Saphenous Vein Graft Aneurysm: A Case-Based Review of Percutaneous Management.
Daniel Walters, Mitul Patel, William F. Penny> ;Cardiovascular Revascularization Medicine. 2019 Feb 8
4 citations
Outcomes of Transradial PCI compared to Transfemoral PCI in veterans with anemia: Insight from the VA Clinical Assessment, Reporting and Tracking (CART) program.
Jayant Bagai, Edward Hess, William F. Penny, Mary E. Plomondon, Stephen W. Waldo> ;Cardiovascular Revascularization Medicine. 2019 Nov 1
20 citations
A cellulose-based photoacoustic sensor to measure heparin concentration and activity in human blood samples.
Ananthakrishnan Soundaram Jeevarathinam, Navin Pai, Kevin Huang, Ali Hariri, Junxin Wang, Yuting Bai, Lu Wang, Tiffany Hancock, Stanley Keys, William F. Penny, Jesse V...> ;Biosensors & Bioelectronics. 2019 Feb 1
11 citations
Design of a Phase 3 trial of intracoronary administration of human adenovirus 5 encoding human adenylyl cyclase type 6 (RT-100) gene transfer in patients with heart fa...
William F. Penny, Timothy D. Henry, Matthew W. Watkins, Amit N. Patel, H. Kirk Hammond> ;American Heart Journal. 2018 Jul 1
Development and Early Experience of the First Joint Military Health System-Veterans Affairs Transcatheter Aortic Valve Replacement Program.
Luke Oakley, Wayne Pritchard, Joelle Colletta, William F. Penny, Steven Romero, Justin Cox, Gilbert Boswell, Joshua Kindelan, Daniel Gramins, Keshav R. Nayak> ;Military Medicine. 2017 Oct 31
17 citations
Randomized Clinical Trials of Gene Transfer for Heart Failure with Reduced Ejection Fraction.
William F. Penny, H. Kirk Hammond> ;Human Gene Therapy. 2017 May 1
Clinical Evaluation of Heart Failure: Agreement among Tests.
Amit K. Pandey, William F. Penny, Valmik Bhargava, N. Chin Lai, Ronghui Xu, H. Kirk Hammond> ;Plos One. 2016 Aug 18
92 citations
Percutaneous Coronary Intervention in Native Coronary Arteries Versus Bypass Grafts in Patients with Prior Coronary Artery Bypass Graft Surgery Insights from the Veter...
Emmanouil S. Brilakis, Colin O'Donnell, William F. Penny, Ehrin J. Armstrong, Thomas T. Tsai, Thomas M. Maddox, Mary E. Plomondon, Subhash Banerjee, Sunil V. Rao, Sant...> ;JACC. Cardiovascular Interventions. 2016 May 9
78 citations
Intracoronary Gene Transfer of Adenylyl Cyclase 6 in Patients With Heart Failure: A Randomized Clinical Trial.
H. Kirk Hammond, William F. Penny, Jay H. Traverse, Timothy D. Henry, Matthew W. Watkins, Clyde W. Yancy, Ranya Sweis, Eric Adler, Amit N. Patel, David Murray, Robert ...> ;JAMA Cardiology. 2016 May 1
8 citations
Percutaneous intervention of an acute left main coronary occlusion due to dissection of the aortic root.
Amir Ravandi, William F. Penny> ;JACC. Cardiovascular Interventions. 2011 Jun 1
11 citations
Comparison of sirolimus-eluting stents with paclitaxel-eluting stents in saphenous vein graft intervention (from a multicenter Southern California Registry).
Michael S. Lee, Patrick Hu, Joseph Aragon, Atman P. Shah, Jared Oyama, Jashdeep Dhoot, Zahid Iqbal, Nathaniel Jones, William F. Penny, Jonathan M. Tobis, Ehtisham Mahm...> ;The American Journal of Cardiology. 2010 Aug 1
6 citations
Impact of chronic renal insufficiency on clinical outcomes in patients undergoing saphenous vein graft intervention with drug-eluting stents: A multicenter Southern Ca...
Michael S. Lee, Patrick Hu, Joseph Aragon, Atman P. Shah, Ravi Bhatia, Nathaniel Jones, William F. Penny, William J. French, Jonathan M. Tobis, Ehtisham Mahmud> ;Catheterization and Cardiovascular Interventions. 2010 Aug 1
81 citations
The Efficacy and Safety of Prasugrel With and Without a Glycoprotein IIb/IIIa Inhibitor in Patients With Acute Coronary Syndromes Undergoing Percutaneous Intervention:...
Michelle L. O'Donoghue, Elliott M. Antman, Eugene Braunwald, Sabina A. Murphy, P. Gabriel Steg, Ariel Finkelstein, William F. Penny, Viliam Fridrich, Carolyn H. McCabe...> ;Journal of the American College of Cardiology. 2009 Aug 18
17 citations
Elevated plasma fibrinogen level predicts suboptimal response to therapy with both single- and double-bolus eptifibatide during percutaneous coronary intervention.
Ehtisham Mahmud, Jeffrey J. Cavendish, Sotirios Tsimikas, Lawrence Ang, Cuong V. Nguyen, Guilherme Bromberg-Marin, Guido Schnyder, Shahin Keramati, Vachaspathi Palakod...> ;Journal of the American College of Cardiology. 2007 Jun 5
11 citations
Impact of age on the outcomes of women following percutaneous coronary intervention in the bare-metal stent era.
Sudhir Rathore, Julie Rhys, Maurice Buchalter, Nick O. Gerning, Pete H. Groves, William F. Penny> ;Journal of Interventional Cardiology. 2006 Jun 1
15 citations
Geographical Differences in the Rates of Angiographic Restenosis and Ischemia-Driven Target Vessel Revascularization After Percutaneous Coronary Interventions: Results...
Mandeep Singh, Brent A. Williams, Bernard J. Gersh, Robyn L. McClelland, Kalon K.L. Ho, James T. Willerson, William F. Penny, Donald E. Cutlip, David R. Holmes> ;Journal of the American College of Cardiology. 2006 Jan 3
14 citations
Endothelial dysfunction after sirolimus-eluting stent placement.
Rod Serry, William F. Penny> ;Journal of the American College of Cardiology. 2005 Jul 19
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Press Mentions

Making Masks Smarter and Safer Against COVID-19January 28th, 2021

Hospital Affiliations

Jennifer Moreno Department of Veterans Affairs Medical CenterSan Diego, California