WilliamW.StringerMDFACP, FCCP

PubMed

• Beyond Spirometry: Linking Wasted Ventilation to Exertional Dyspnea in the Initial Stages of COPD.
  Neder, J., Santyr, G., Zanette, B., Kirby, M., Pourafkari, M., James, M., Vincent, S., Ferguson, C., Wang, C., Domnik, N., Phillips, D., Porszasz, J., O'Donnell, D., S...> ;COPD. 2024 Dec 1
• Lack of effect of an in-line filter on cardiopulmonary exercise testing variables in healthy subjects.
  Asghar Abbasi, Khadije Ahmad, Carrie Ferguson, April Soriano, Robert Calmelat, Harry B Rossiter, Richard Casaburi, William W Stringer, Janos Porszasz> ;European Journal of Applied Physiology. 2024 Mar 1
• 3 citations
  Current definitions of the breathing cycle in alveolar breath-by-breath gas exchange analysis.
  Michele Girardi, Chiara Gattoni, William W Stringer, Harry B Rossiter, Richard Casaburi, Carrie Ferguson, Carlo Capelli> ;American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 2023 Nov 1
• Letter to the editor in response to Hoskote "Corrected formula for rectangular area ratio (RAR), a parameter used to quantify airflow limitation on expiratory flow-vol...
  Janos Porszasz, Chu-Yi Wang, Carrie Ferguson, Shuyi Ma, Michele Girardi, William W Stringer> ;Respiratory Medicine. 2023 May 29
• 2 citations
  Exercise-induced increases in "liver function tests" in a healthy adult male: Is there a knowledge gap in primary care?
  Nicholas B Tiller, William W Stringer> ;Journal of Family Medicine and Primary Care. 2023 Jan 1
• 26 citations
  Bronchodilators in Tobacco-Exposed Persons with Symptoms and Preserved Lung Function.
  MeiLan K Han, Wen Ye, Di Wang, Emily White, Mehrdad Arjomandi, Igor Z Barjaktarevic, Stacey-Ann Brown, Russell G Buhr, Alejandro P Comellas, Christopher B Cooper, Gera...> ;The New England Journal of Medicine. 2022 Sep 29
• 3 citations
  Heart Rate Variability on 10-Second Electrocardiogram and Risk of Acute Exacerbation of COPD: A Secondary Analysis of the BLOCK COPD Trial.
  David M MacDonald, Takudzwa Mkorombindo, Sharon X Ling, Selcuk Adabag, Richard Casaburi, John E Connett, Erika S Helgeson, Janos Porszasz, Harry B Rossiter, William W ...> ;Chronic Obstructive Pulmonary Diseases. 2022 Apr 29
• Chronotropic index during 6-minute walk and acute respiratory events in COPDGene.
  David M Macdonald, Elise F Palzer, Asghar Abbasi, Arianne K Baldomero, Surya P Bhatt, Richard Casaburi, John E Connett, Mark T Dransfield, Nathaniel T Gaeckle, Takudzw...> ;Respiratory Medicine. 2022 Apr 1
• 2 citations
  Chronotropic Index and Acute Exacerbations of Chronic Obstructive Pulmonary Disease: A Secondary Analysis of BLOCK COPD
  David M MacDonald, Erika S. Helgeson, Selcuk Adabag, Richard Casaburi, John E. Connett, William W. Stringer, Helen Voelker, Mark T. Dransfield, Ken M. Kunisaki> ;Annals of the American Thoracic Society. 2021 Nov 1
• 7 citations
  Emphysema Progression and Lung Function Decline Among Angiotensin Converting Enzyme Inhibitors and Angiotensin-Receptor Blockade Users in the COPDGene Cohort.
  Vickram Tejwani, Ashraf Fawzy, Nirupama Putcha, Peter J. Castaldi, Michael H. Cho, Katherine A. Pratte, Surya P. Bhatt, David A. Lynch, Stephen M. Humphries, Gregory L...> ;Chest. 2021 Oct 1
• 6 citations
  Identifying a Heart Rate Recovery Criterion After a 6-Minute Walk Test in COPD
  Dongxing Zhao, Asghar Abbasi, Richard Casaburi, Alessandra Adami, Nicholas B. Tiller, Wei Yuan, Christopher Yee, Nicholas G. Jendzjowsky, David M MacDonald, Ken M. Kun...> ;International Journal of Chronic Obstructive Pulmonary Disease. 2021 Sep 4
• 6 citations
  The Association between Lung Hyperinflation and Coronary Artery Disease in Smokers.
  Divay Chandra, Aman Gupta, Gregory L. Kinney, Carl R. Fuhrman, Joseph K. Leader, Alejandro A. Diaz, Jessica Bon, R. Graham Barr, George R. Washko, Matthew J. Budoff, J...> ;Chest. 2021 Sep 1
• 4 citations
  Haemoglobin as a biomarker for clinical outcomes in chronic obstructive pulmonary disease.
  Aparna Balasubramanian, Robert J. Henderson, Nirupama Putcha, Ashraf Fawzy, Sarath Raju, Nadia N. Hansel, Neil R. MacIntyre, Robert L. Jensen, Gregory L. Kinney, Willi...> ;ERJ Open Research. 2021 Jul 1
• 3 citations
  Dynamic airway function during exercise in COPD assessed via impulse oscillometry before and after inhaled bronchodilators.
  Nicholas B. Tiller, Min Cao, Fang Lin, Wei Yuan, Chu-Yi Wang, Asghar Abbasi, Robert Calmelat, April Soriano, Harry B. Rossiter, Richard Casaburi, William W. Stringer, ...> ;Journal of Applied Physiology. 2021 May 20
• 3 citations
  The Effect of Long-Acting Dual Bronchodilator Therapy on Exercise Tolerance, Dynamic Hyperinflation and Dead Space during Constant Work Rate Exercise in COPD.
  William W. Stringer, Janos Porszasz, Min Cao, Harry B. Rossiter, Shahid Siddiqui, Stephen I. Rennard, Richard Casaburi> ;Journal of Applied Physiology. 2021 Apr 29
• 8 citations
  Transcutaneous PCO2 for Exercise Gas Exchange Efficiency in Chronic Obstructive Pulmonary Disease.
  Min Cao, William W. Stringer, Susan Corey, Robert Cao, Robert Calmelat, Fang Lin, Richard Casaburi, Harry B. Rossiter, Janos Porszasz> ;COPD. 2021 Jan 17
• 1 citations
  Safety and stability of pulmonary function in patients with decreased respiratory function treated for spasticity with onabotulinumtoxinA
  Ziyad Ayyoub, Allison Brashear, Marta Banach, Robert B. Schoene, William W. Stringer, Terry Boodhoo, Irina Yushmanova, Rozalina Dimitrova, Mitchell F. Brin> ;Toxins. 2020 Oct 19
• 2 citations
  Are We Treating Heart Failure in Patients with Chronic Obstructive Pulmonary Disease Appropriately
  William W. Stringer> ;Annals of the American Thoracic Society. 2020 Jul 31
• 21 citations
  Dyspnea Postpulmonary Embolism From Physiological Dead Space Proportion and Stroke Volume Defects During Exercise
  Timothy M. Fernandes, Mona Alotaibi, William W. Stringer, Janos Porszasz, Garner George Faulkner, Cara Castro, Don A. Tran, Timothy A. Morris> ;Chest. 2020 Apr 1
• 28 citations
  Disease Progression Modeling in Chronic Obstructive Pulmonary Disease
  Alexandra L. Young, Felix J. S. Bragman, Bojidar Rangelov, MeiLan K. Han, Craig J. Galbán, David A. Lynch, David J. Hawkes, Daniel C. Alexander, John R. Hurst, James D...> ;American Journal of Respiratory and Critical Care Medicine. 2020 Feb 1
• 51 citations
  Diffusing Capacity of Carbon Monoxide in Assessment of COPD.
  Aparna Balasubramanian, Neil R. MacIntyre, Robert J. Henderson, Robert L. Jensen, Gregory L. Kinney, William W. Stringer, Craig P. Hersh, Russell P. Bowler, Richard Ca...> ;Chest. 2019 Dec 1
• 20 citations
  A New Bronchodilator Response Grading Strategy Identifies Distinct Patient Populations.
  James E. Hansen, Asli Gorek Dilektasli, Janos Porszasz, William W. Stringer, Youngju Pak, Harry B. Rossiter, Richard Casaburi> ;Annals of the American Thoracic Society. 2019 Nov 27
• 89 citations
  COPDGene® 2019: Redefining the Diagnosis of Chronic Obstructive Pulmonary Disease.
  Bhatt, S. P., Katherine E Lowe, Elizabeth A. Regan, Antonio Anzueto, Erin Austin, John H. M. Austin, Terri H. Beaty, Panayiotis V. Benos, Christopher J. Benway, Surya ...> ;Chronic Obstructive Pulmonary Diseases. 2019 Nov 1
• 87 citations
  Metoprolol for the Prevention of Acute Exacerbations of COPD.
  Mark T. Dransfield, Helen Voelker, Surya P. Bhatt, Keith Brenner, Richard Casaburi, Carolyn E. Come, J. D.Allen Cooper, Gerard J. Criner, Jeffrey L. Curtis, MeiLan K. ...> ;The New England Journal of Medicine. 2019 Oct 20
• 31 citations
  The St. George's Respiratory Questionnaire Definition of Chronic Bronchitis May Be a Better Predictor of COPD Exacerbations Compared With the Classic Definition.
  Victor Kim, Huaqing Zhao, E.A. Regan, MeiLan K. Han, Barry J. Make, James D. Crapo, Paul W. Jones, Jeffrey L. Curtis, Edwin K. Silverman, Gerard J. Criner, Elizabeth A...> ;Chest. 2019 Oct 1
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Journal Articles

• Information strategies that work for physicians.  
  W. W. Stringer, Hospital Practice, 32:8, pp. 105-106
• Digital Technology meets the Banjo.  
  W. W. Stringer, Banjo Newsletter
• WWW Banjo: What in the World do you Want for your Banjo.  
  W. W. Stringer, Banjo Newsletter
• Men who maintained or improved physical fitness had reduced risk for all-cause and CVD mortality.  
  Stringer, W.W., ACP Journal Club, 123:52-53
• Total physical activity and mortality were inversely related in men.  
  Stringer, W.W., ACP Journal Club, 123:52-53
• Lactic acid is the only physiochemical contributor to the metabolic acidosis of exercise.  
  E.S. Prakash, R. A. Robergs, B.F. Miller, L. B. Gladden, N. Jones, W.W. Stringer, K Wasserman, W. Moll, Gerolf Gross, D.S. Rowlands, Kend Sahlin, and R. Beneke., J Allied. Physiol. 105 (1): 363-268
• The CO2- O2 relationship reflects the rate of lactic acid accumulation during heavy constant work rate exercise.  
  W.W. Stringer, K. Wasserman, and R.Casaburi, Eur. J. Appl. Physiol. 72: 25-31
• Newly diagnosed profound hypoxia and pulmonary hypertension.  
  J. Silflow, E. Yang, G. DiSibio, S. French, A. Mlikotic, and W.W. Stringer, Published in the UCLA Proceedings for Health Care
• Clinical relevance of changes in endurance time during constant high intensity exercise in patients with chronic obstructive lung disease.  
  L. Puente-Maestu, F. Villar, J. de Miguel, S. Lucero, and W.W. Stringer, European Respiratory Journal: 34 (2)
• A simple new visualization of exercise data discloses pathophysiology and severity of heart failure.  
  Xinguo Sun, J.E. Hansen, and W.W. Stringer, in the online Journal of the American Heart Association
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Books/Book Chapters

• Equipment, Measurements, and Quality Control in Clinical Exercise Testing. 
  Chapter: Clinical Exercise Testing 
  J. Porszasz, W.W. Stringer, and Richard CasaburiEditors: S.A. Ward and P. Palange.A European Respiratory Society Task Force Project
• Blood oxygen and carbon dioxide transport during exercise. 
  Chapter: Principles of Exercise Testing and Interpretation 
  W. W. Stringer and J.E. HansenEditors: Wasserman, K., Hansen, J., Sue, D., Stringer W. W., and B.J. Whipp.Lippincott, Williams, & Wilkins
• Physical Activity and Quality of Life in HIV+ Individuals. 
  Chapter: Exercise, Health, and Mental Health: Emerging Relationships 
  W. W. StringerEditors: Guy Faulkner, PhD.Biddle, Fox and Boutcher,
• HIV, AIDS, and Exercise. 
  Chapter: Medicine and Exercise Science: Application and Physiological Principles 
  W. W. StringerEditors: L. Lemura.Lippincott, Williams & Wilkins
• Homeostasis of Exercise Gas Exchange: Coupling of Pulmonary and Cardiovascular Function to Cellular Respiration during Exercise. 
  Chapter: Respiratory-Circulation Interactions in Health and Disease 
  K. Wasserman and W. W. StringerEditors: S. Scharf, M. Pinsky and S. Magder.Marcel Dekker
• Principles of Exercise Testing and Interpretation: Including Pathophysiology and Clinical Applications 
  Karlman Wasserman, James E. Hansen MD, and Darryl Y. Sue MD and William W. Stringer MDLippincott, Williams, and & WilkinsEdition 5, P,
• Acid-base regulation and ventilatory control during exercise and recovery in man. 
  Chapter: Control of breathing and its modeling perspectives 
  K. Wasserman, W. W. Stringer, and R. Casaburi.Editors: Y. Honda, et al.Plenum Press, New York
• Principles of Exercise Testing and Interpretation 
  Wasserman, Karlman, Hansen, James, Sue, Darryl, Stringer William W., and Brian J. WhippLippincott, Williams, and WilkinsEdition 4,
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Abstracts/Posters

• Critical capillary PO2 and muscle capillary recruitment during exercise.
  30. K. Wasserman, W. W. Stringer and A. Koike, ATS/ALA Meeting, San Diego, California
• Arterial hydrogen ion regulation and the exercise hyperpnea.
  W. L. Beaver, K. Wasserman, W. W. Stringer, and R. Casaburi, Presented at the Oxford Conference, England
• Exercise training augments immune function in HIV+ patients.
  W. W. Stringer, M Berezovskaya, C. Sullivan, K. Beck, and R. Casaburi, Presented at the UniversityWide AIDS Research Program
• Dynamic interrelationships underlying the exercise hyperpnea during heavy sinusoidal exercise.
  W. W. Stringer, R. Casaburi , J Pórszász , E. Singer, and K. Wasserman, Presented at the ATS/ALA Meeting, Seattle, Wash
• Are patients with lung disease limited by abnormal lung mechanics during exercise?
  C. Master, W. W. Stringer, J. Abe, D. Sue, B. Whipp, and K. Wasserman, Presented at the ATS/ALA Meeting, Seattle, Wash
• Dynamic changes in femoral vein acid-base balance and potassium at the start of exercise.
  K. Wasserman , W. W. Stringer, Y. Y. Zhang, R. Casaburi, resented at the American Heart Association Scientific Session, Anaheim California
• Dynamics and mechanism of K+ release from exercising muscle.
  K. Wasserman , W. W. Stringer, Y. Y. Zhang, R. Casaburi, Presented at the Experimental Biology 96 meeting
• Electronic Systems to Improve Primary Care.
  W. W. Stringer, Presented at the HIMSS 2001 Meeting,, New Orleans, LA
• The effect of airflow obstruction on exercise capacity and breathing reserve in COPD.
  S. Juthong, W.K. Lam, B. Chuaychoo, J.E. Hansen, W.W. Stringer, and K. Wasserman, Presented at the ATS meeting, San Francisco California
• Multiple rapid cycle interventions in a safety net hospital can improve processes of care and outcomes in an anticoagulation clinic.
  G. S. Nakagawa, C.R. McKay, J.J. French, D.F. Levin, W.W. Stringer, D.M. Terrell, C.E. Tapia, W.S. Kamikawa, . Presented at the American Heart Associations 3rd Scientific Forum on Quality of Care and Outcomes, Washington DC
• Understanding women’s needs when communicating breast cancer risk information.
  L. Lillington, RN, DNSc, E. Garcia, M.A., R. Chlebowski, MD, PhD, and W. W. Stringer, MD, Presented at the Oncology Nursing Society Research Conference
• Peritoneal tuberculosis two years after a positive purified protein derivative (PPD) skin test in an immunocompentent host.
  G. Cheng and W. W. Stringer, Presented at Chest
• Time course of pulmonary artery (PA) and inferior vena cava (IVC) blood gas changes at the start of exercise.
  W.W. Stringer, K Wasserman, and R. Casaburi, Slide presentation at Chest
• Lactate/Pyruvate Ratio in the Arterial and Femoral Venous Systems during Ramp Exercise.
  W.W. Stringer, B.J. Whipp, J. Porszasz, and K Wasserman, Presented at the IUPS Experimental Biology Meeting, San Diego, California
• Exercise capacity in clinically stable HIV patients as a function of antiretroviral therapy.
  W.W. Stringer, M.Witt, M.Cao. A. Nguyen, R. Sandoval and K Sietsema, Presented at Chest, Montreal, Canada
• Left ventricle function effects on damping and control of breathing.
  X-G Sun and W.W. Stringer, Chest, Honolulu, Hawaii
• Possible role of enteropancreatic circulation in pancreatic imaging.
  L.E. Goldberger, W.W. Stringer, J.L. Barnhart, R.N. Berk, Gastrointestinal Radiology 5:(1) 85-85
• Tissue oxygenation by near infrared spectrophotometry (NIRS) during moderate and heavy exercise.
  T.J. Barstow, J.M. Ren, W.W. Stringer, B. Chance, and K. Wasserman, FASEB J 4:A690
• Kinetics of bicarbonate and non-bicarbonate buffering of lactic acid during heavy exercise.
  W.W. Stringer, R. Casaburi, and K. Wasserman, Am Rev Resp Dis 143: A175
• Mechanism of the abrupt fall in mixed venous oxygen saturation at the onset of exercise.
  R. Casaburi, W. French, W. W. Stringer, T.Barstow, and P. Abdel-Sayed, Med. Science Sports Exercise 23:S132
• A theoretical analysis of the spatial inhomogeneity of lactate kinetics in response to exercise.
  Y. Fukuba, W. W. Stringer, and K. Wasserman, Presented at the 8th International Biochemistry of Exercise Conference, Nagoya Japan
• The role of pH in maintaining muscle capillary pO2 during heavy exercise.
  W. W. Stringer, R. Casaburi, W. French, J. Pórszász, K. Wasserman, Am. Rev. Respir. Dis. 145:A881
• Detection of lactic acidosis following the onset of heavy exercise from analysis of CO2 and O2 kinetics.
  W. W. Stringer, R. Casaburi, W. French, J. Pórszász, and K Wasserman, FASEB J 6:A1236
• Influence of oral bicarbonate loading on the physiologic responses to exercise.
  R. Casaburi, W. W. Stringer, W. French, J. Pórszász, and K. Wasserman, FASEB J 6:A1236
• Arteriovenous CO2 vs O2 difference manifests threshold behavior similar to O2 and O2.
  W. W. Stringer, K. Wasserman, W. French, J. Pórszász, and R. Casaburi, Am. Rev. Respir. Dis. 147:A192
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Lectures

• IXth Practicum on Cardiopulmonary Exercise Testing. 
  Gunma Prefecture Cardiovascular Center, Maebashi, Japan
• Medical Aspects of the Civil War. 
  Department of Medicine Grand Rounds, Harbor-UCLA Medical Center
• Asthma Update for 2005. 
  Riverside, California
• Current Asthma Management - 2005. 
  Primary Care Grand Rounds, Harbor-UCLA Medical Center
• Carbon Dioxide Transport. 
  Respiratory Physiology Lecture Series, Harbor-UCLA Medical Center
• Music, Mozart, and Medicine. 
  Los Angeles Biomedical Institute Fund Raiser, Palos Verdes, California
• Update on Harbor. 
  Department of Medicine Housestaff Retreat, Arrowhead, California
• Lung Cancer & Screening. 
  Primary Care Grand Rounds, Harbor-UCLA Medical Center
• Principles of Exercise Testing and Interpretation: A Case Based Approach. 
  Co-Chair, ACCP Post Graduate Course at Chest 2005, Montreal, Canada
• The Physiologic Basis of Pulmonary Function Testing. 
  Session Co-Chair, Chest 2005, Montreal, Canada
• Evidence-Based Medicine and Cardiopulmonary Exercise Testing: Has Art Met Science? 
  WWS Panel Discussion Chair and Speaker, Chest 2005, Montreal, Canada
• Music, Myth, and Medicine – Beethoven. 
  Long Beach Music Teachers Association, Long Beach, California (2005)
• Asthma Update: 2006. 
  Department of Medicine Grand Rounds. Harbor-UCLA Medical Center, Torrance, CA
• Beethoven: How his life struggles affected his music. 
  Primary Care Lecture Series, Harbor-UCLA Medical Center, Torrance, California
• Fluid Management Strategies in Acute Lung Injury. 
  Department of Medicine Grand Rounds, Torrance, Torrance, CA
• Update in Pulmonary Medicine for Primary Care Practitioners. 
  Family Medicine Lecture Series, Harbor-UCLA Medical Center, Torrance, California
• Tuberculosis: What’s old? What’s new? 
  Pulmonary Grand Rounds, Torrance, California
• State of the Department of Medicine, Harbor-UCLA Medical Center. 
  Department of Medicine Housestaff Retreat, Arrowhead, California
• Interesting Pulmonary Function and Exercise Cases: How does the Information from Cardiopulmonary Exercise Testing add to Pulmonary Function Testing? 
  Session Chair, Chest 2006 Annual Meeting, Salt Lake City, Utah.
• Update in Mechanical Ventilation. 
  Surgery Grand Rounds, Harbor-UCLA Medical Center, Torrance, California
• Mechanical Ventilation – 2006. 
  Department of Medicine Grand Rounds
• Lung Cancer in Women. 
  Rose Madden Conference, Torrance Cultural Arts Center
• Mozart and Medicine. 
  Primary Care Lecture Series, Torrance, California
• Diagnosis and Management of Acute Respiratory Failure. 
  Fundamental Critical Care Support (FCCS) Course,Martin Luther King, Jr. – Hospital
• COPD: Update on an old friend (enemy?). 
  Pulmonary Grand Rounds,Harbor-UCLA Medical Center
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