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X. Long Zheng, MD, Pathology, Kansas City, KS, The University of Kansas Hospital

X. LongZhengMDPhD

Pathology Kansas City, KS

Blood Banking & Transfusion Medicine, Chemical Pathology, Transplantation Immunology, Clinical Pathology

Professor and Chair of Pathology and Laboratory Medicine, University of Kansas Medical Center, KS

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  • Office

    University of Kansas Medical Center
    3901 Rainbow Blvd
    Kansas City, KS 66160
    Phone(913) 588-7071
    Fax(913) 588-7073
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  • I am board certified pathologist, specialized in laboratory medicine, transfusion medicine, and coagulation. My laboratory focuses on understanding the molecular mechanism of thrombotic thrombocytopenic purpura (TTP) and atypical hemolytic uremic syndrome and developing novel diagnostic and therapeutic tools for these rare but potentially fatal disorders.

Education & Training

  • Washington University - Barnes-Jewish Hospital
    Washington University - Barnes-Jewish HospitalFellowship, Blood Banking/Transfusion Medicine, 2002 - 2003
  • Washington University - Barnes-Jewish Hospital
    Washington University - Barnes-Jewish HospitalResidency, Clinical Pathology, 1999 - 2002
  • University of ViennaPh.D., Mol. Cell. Biology, 1991 - 1994
  • Tongji Medical College, Huazhong University of Science and TechnologyMSc, Obs/Gyn, 1987
  • Medical College of Nanchang UniversityClass of 1984, M.D.

Certifications & Licensure

  • KS State Medical License
    KS State Medical License 2020 - 2022
  • Alabama Sate Medical License
    Alabama Sate Medical License, AL 2014 - Present
  • NJ State Medical License
    NJ State Medical License 2008 - 2021
  • PA State Medical License
    PA State Medical License 2003 - 2022
  • American Board of Pathology Clinical Pathology
  • American Board of Pathology Blood Banking/Transfusion Medicine

Awards, Honors, & Recognition

  • Gift-of-Life Award RayWinn Foundation, NJ, 2014
  • Karl-Link New Investigator Award for Hemostasis ATVB, American Heart Association, 2012
  • PhD Student Scholarship Austrian Science Foundation, 1991
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Publications & Presentations


Journal Articles

  • Understanding thrombotic microangiopathies in children  
    Joly BS, Zheng XL and Veyradier A, Inten Care Med, 1/24/2018
  • Low Plasma ADAMTS13 Activity is Associated with Coagulopathy, Endothelial Cell Damage and Mortality after Severe Pediatric Trauma  
    Russell RT, McDaniel JK, Cao WJ, Shroyer M, Wagener BM, Zheng XL (corr. au.), JF Pittet, Thromb Haemost, 1/1/2018
  • Novel factor VIII variants with a modified furin cleavage site improve the efficacy of gene therapy for hemophilia A  
    Nguyen GN, George LA, Siner JI, Davidson RJ, Zander CB, Zheng XL, Arruda VR, Camire RM, Sabatino DE, J Thromb Haemost, 1/1/2017
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Books/Book Chapters


  • Longitudinal Assessment of Plasma ADAMTS13 Biomarkers Helps Predict Recurrence of Immune Thrombotic Thrombocytopenic Purpura
    X. Long Zheng, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/8/2019
  • Plasma Levels of Histone-DNA Complex and Cell-Free DNA Predict Mortality in Patients with Immune Thrombotic Thrombocytopenic Purpura
    X. Long Zheng, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019
  • African American Race Is Associated with Decreased Relapse-Free Survival in Immune Thrombotic Thrombocytopenic Purpura
    X. Long Zheng, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019


  • TTP: from bench to bedside 
    San Francisco, CA - 1/1/2018
  • aHUS: Evidence Based Guidelines in Therapeutic Apheresis 
    Dallas, TX - 1/1/2018
  • HUS: Dual Presentation Diagnosis and Treatment 
    Westchester Medical Center, Valhalla, NY - 1/1/2018
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Grant Support

  • Novel Therapeutics for Thrombotic Thrombocytopenic PurpuraNHLBI2019–2024
  • Zebrafish model of Thrombotic Thrombocytopenic PurpuraAmerican Heart Association (Mentor)2019–2020
  • Complement activation in pathogenesis of TTPAnswering T.T.P. Foundation2015–2020
  • Pathogenesis of Thrombotic MicroangiopathyNHLBI2015–2020
  • Structure and function of ADAMTS13NHLBI2005–2010
  • Cofactor-dependent regulation of VWF proteolysisNHLBI2005–2010

Research History

  • Professor at University of Alabama at Birmingham, Birmingham, AL2015 - 2020
  • Associate Professor at University of Pennsylvania, Philadelphia, PA2011 - 2015
  • Assistant Professor at University of Pennsylvania, Philadelphia, PA2003 - 2011
  • Postdoctoral fellow, Washington University in St. Louis, MO1995 - 1999

Professional Memberships

Other Languages

  • Chinese (Mandarin), German

Hospital Affiliations

Industry Relationships

  • Consultant, Takeda2019 - Present
  • Speaker, Sanofi-Genzyme2019 - Present
  • Co-founder, Clotsolution2018 - Present
  • Speaker, Alexion2012 - Present