XianhuaPiaoMD

Neonat/Perinatology • Boston, MA

Assistant Professor of Pediatrics, Boston Children's Hospital

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Office
300 Longwood Ave
Enders 961.2
Boston, MA 02115
Phone(617) 919-2356
Fax(617) 730-0260
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Education & Training

Boston Children's HospitalFellowship, Neonatal-Perinatal Medicine, 1999 - 2002
NYU School of MedicineResidency, Pediatrics, 1997 - 1999
Bridgeport HospitalInternship, Transitional Year, 1996 - 1997
Fourth Military Medical University Class of 1984

Certifications & Licensure

CA State Medical License 2018 - 2022
MA State Medical License 1999 - 2021
American Board of Pediatrics Neonatal-Perinatal Medicine

Publications & Presentations

PubMed

The expanding functional roles and signaling mechanisms of adhesion G protein-coupled receptors.
Rory K. Morgan, Garret R. Anderson, Demet Araç, Gabriela Aust, Nariman Balenga, Antony A. Boucard, James P. Bridges, Felix B. Engel, Caroline J. Formstone, Maike D. Gl...> ;Annals of the New York Academy of Sciences. 2019 Nov 1
Long noncoding RNAs interact with mRNAs: A new perspective on the mechanism of premature brain injury.
Ru-Juan Chen, Xianhua Piao, Mi Xiao, Fan Wang, Li Liu> ;Neuroscience Letters. 2019 Aug 10
Overlap of polymicrogyria, hydrocephalus, and Joubert syndrome in a family with novel truncating mutations in ADGRG1/GPR56 and KIAA0556.
Edmund Cauley, Ahlam A. Hamed, Inaam N. Mohamed, Maha A. Elseed, Samantha Martinez, Ashraf Yahia, Fatima Abozar, Rayan Abubakr, Mahmoud Koko, Liena E. O. Elsayed, Xian...> ;Neurogenetics. 2019 Apr 13
Adhesion G Protein-Coupled Receptors as Drug Targets for Neurological Diseases.
Christopher J. Folts, Stefanie Giera, Tao Li, Xianhua Piao> ;Trends in Pharmacological Sciences. 2019 Apr 1
Single-Cell RNA Sequencing of Microglia throughout the Mouse Lifespan and in the Injured Brain Reveals Complex Cell-State Changes.
Timothy R. Hammond, Connor Dufort, Lasse Dissing-Olesen, Stefanie Giera, Adam Young, Alec Wysoker, Alec J. Walker, Frederick Gergits, Michael Segel, James Nemesh, Samu...> ;Immunity. 2019 Jan 15
The adhesion receptor GPR56 is activated by extracellular matrix collagen III to improve β-cell function
Oladapo E Olaniru, Attilio Pingitore, Stefanie Giera, Xianhua Piao, Ramón Castañera González, Peter M. Jones, Shanta J. Persaud> ;Cellular and Molecular Life Sciences. 2018 May 31
Microglial transglutaminase-2 drives myelination and myelin repair via GPR56/ADGRG1 in oligodendrocyte precursor cells
Stefanie Giera, Rong Luo, Yanqin Ying, Sarah D. Ackerman, Sung-Jin Jeong, Hannah M. Stoveken, Christopher J. Folts, Christina A. Welsh, Gregory G. Tall, Beth Stevens, ...> ;eLife. 2018 May 29
GPR56/ADGRG1 regulates development and maintenance of peripheral myelin.
Sarah D. Ackerman, Rong Luo, Yannick Poitelon, Amit Mogha, Breanne L. Harty, Mitchell D’Rozario, Nicholas E. Sanchez, Asvin K. K. Lakkaraju, Paul Gamble, Jun Li, Jun Q...> ;Journal of Experimental Medicine. 2018 Mar 5
GPR56/ADGRG1 Inhibits Mesenchymal Differentiation and Radioresistance in Glioblastoma
Marta Moreno, Leire Pedrosa, Laia Paré, Estela Pineda, Leire Bejarano, Josefina Martínez, Veerakumar Balasubramaniyan, Ravesanker Ezhilarasan, Naveen Kallarackal, Sung...> ;Cell Reports. 2017 Nov 21
Novel Mutation in CNTNAP1 results in Congenital Hypomyelinating Neuropathy
Paulomi Mehta, Melanie Küspert, Tejus A. Bale, Catherine A. Brownstein, Meghan C. Towne, Umberto De Girolami, Jiahai Shi, Alan H. Beggs, Basil T. Darras, Michael Wegne...> ;Muscle & Nerve. 2017 May 1
1 citations
Adhesion G-protein coupled receptors and extracellular matrix proteins: Roles in myelination and glial cell development.
Paulomi Mehta, Xianhua Piao> ;Developmental Dynamics. 2017 Apr 1
4 citations
Gpr126/Adgrg6 Has Schwann Cell Autonomous and Nonautonomous Functions in Peripheral Nerve Injury and Repair
Xianhua Piao, MD> ;The Journal of Neuroscience. 2016 Dec 9
24 citations
Role of macrophages in Wallerian degeneration and axonal regeneration after peripheral nerve injury.
Chen, P., Piao, X., Bonaldo, P.> ;Acta neuropathologica. 2015 Oct 1
The Adhesion GPCR GPR126 Has Distinct, Domain-Dependent Functions in Schwann Cell Development Mediated by Interaction with Laminin-211
Sarah C. Petersen, Rong Luo, Ines Liebscher, Stefanie Giera, Sung-Jin Jeong, Amit Mogha, Monica Ghidinelli, M. Laura Feltri, Torsten Schöneberg, Xianhua Piao, Kelly R....> ;Neuron. 2015 Feb 18
1 citations
The adhesion G protein-coupled receptor GPR56 is a cell-autonomous regulator of oligodendrocyte development.
Giera, S., Deng, Y., Luo, R., Ackerman, S. D., Mogha, A., Monk, K. R., Ying, Y., Jeong, S., Makinodan, M., Bialas, A. R., Chang, B. S., Stevens, B., Corfas, G., Piao, X.> ;Nature communications. 2015 Jan 22
G protein-coupled receptor 56 regulates mechanical overload-induced muscle hypertrophy.
James P. White, Christiane D. Wrann, Rajesh R. Rao, Sreekumaran Nair, Mark P. Jedrychowski, Jae-Sung You, Vicente Martínez-Redondo, Steven P. Gygi, Jorge L. Ruas, Troy...> ;Proceedings of the National Academy of Sciences of the United States of America. 2014 Nov 4
1 citations
Mechanism for adhesion G protein-coupled receptor GPR56-mediated RhoA activation induced by collagen III stimulation.
Luo, R., Jeong, S., Yang, A., Wen, M., Saslowsky, D. E., Lencer, W. I., Araç, D., Piao, X.> ;PloS one. 2014 Jun 21
Evolutionarily Dynamic Alternative Splicing of GPR56 Regulates Regional Cerebral Cortical Patterning
Byoung-Il Bae, Ian Tietjen, Kutay Deniz Atabay, Gilad D. Evrony, Matthew B. Johnson, Ebenezer Asare, Peter P. Wang, Ayako Murayama, Kiho Im, Steven Lisgo, Lynne M. Ove...> ;Science. 2014 Feb 14
15 citations
G-protein coupled receptor 56 promotes myoblast fusion through serum response factor- and nuclear factor of activated T-cell-mediated signalling but is not essential f...
Melissa P. Wu, Jamie R. Doyle, Brenda J. Barry, Ariane Beauvais, Anete Rozkalne, Xianhua Piao, Michael W. Lawlor, Alan S. Kopin, Christopher A. Walsh, Emanuela Gussoni> ;FEBS Journal. 2013 Dec 1
GPR56 Functions Together with α3β1 Integrin in Regulating Cerebral Cortical Development
Sung-Jin Jeong, Rong Luo, Kathleen Singer, Stefanie Giera, Jordan A. Kreidberg, Daiji Kiyozumi, Chisei Shimono, Kiyotoshi Sekiguchi, Xianhua Piao> ;PLOS ONE. 2013 Jul 9
GPR56 and the Developing Cerebral Cortex: Cells, Matrix, and Neuronal Migration
Kathleen Singer, Rong Luo, Sung-Jin Jeong, Xianhua Piao> ;Molecular Neurobiology. 2013 Feb 1
Characterization of G protein-coupled receptor 56 protein expression in the mouse developing neocortex.
Sung-Jin Jeong, Rong Luo, Shihong Li, Natalie Strokes, Xianhua Piao> ;The Journal of Comparative Neurology. 2012 Sep 1
2 citations
Disease-associated mutations prevent GPR56-collagen III interaction.
Luo, R., Jin, Z., Deng, Y., Strokes, N., Piao, X.> ;PloS one. 2012 Jan 13
11 citations
Loss of Col3a1, the gene for Ehlers-Danlos syndrome type IV, results in neocortical dyslamination.
Jeong, S., Li, S., Luo, R., Strokes, N., Piao, X.> ;PloS one. 2012 Jan 12
2 citations
A novel GPR56 mutation causes bilateral frontoparietal polymicrogyria.
Luo, R., Yang, H. M., Jin, Z., Halley, D. J., Chang, B. S., MacPherson, L., Brueton, L., Piao, X.> ;Pediatric neurology. 2011 Jul 5
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