Xiusheng Qin MD PhD

PubMed

• 39 citations
  DNA repair and cancer: lessons from mutant mouse models.
  Takatoshi Ishikawa, Samuel Shao Min Zhang, Xiusheng Qin, Yoshihisa Takahashi, Hideaki Oda
  Cancer Science. 2004-02-01
• 17 citations
  Lung tumorigenesis associated with erb-B-2 and erb-B-3 overexpression in human erb-B-3 transgenic mice is enhanced by methylnitrosourea.
  Hang Zhou, Lili Liu, Keunmyoung Lee, Xiusheng Qin, Adam W. Grasso
  Oncogene. 2002-12-12
• 19 citations
  MMTV promoter hypomethylation is linked to spontaneous and MNU associated c-neu expression and mammary carcinogenesis in MMTV c-neu transgenic mice.
  Hang Zhou, Wei Dong Chen, Xiusheng Qin, Keunmyoung Lee, Lili Liu
  Oncogene. 2001-09-20

Journal Articles

• Inhibitory effects of probucol on nephrotoxicity induced by ferric nitrilotriacetate (Fe-NTA) in rats.  
  Qin, X., Zhang, S., Zarkovic, M., Yamazaki, Y., Oda, H., Nakatsuru, Y., Ishikawa, T. and Ishikawa, T, Carcinogenesis, 16:2549-2552
• MMTV promoter hypomethylation is linked to spontaneous and MNU associated c-neu expression and mammary carcinogenesis in MMTV c-neu transgenic mice.  
  Zhou, H., Chen, W.D., Qin, X., Lee, K., Liu, L., Markowitz, S.D. and Gerson, S.L, Oncogene, 20: 6009-6017
• Differential degradation rates of inactivated alkyltransferase in blood mononuclear cells and tumors of patients after treatment with O(6)-benzylguanine.  
  Liu, L., Spiro, TP., Qin, X., Majka, S., Haaga, J., Schupp, J., Willson, JK., Gerson, SL, Clin Cancer Res., 7: 2318-2324
• Importance of DNA repair in carcinogenesis: evidence from transgenic and gene targeting studies.  
  Ishikawa, T., Ide, F., Qin, X., Takahashi, Y., Sekiguchi, M., Tanaka, K. and Nakatsuru, Y, Mutat. Res., 2:477:41-49
• MGMT expression in murine bone marrow is a major determinant of animal survival after alkylating agent exposure.  
  Reese, JS., Qin, X., Ballas, CB., Sekiguchi, M. and Gerson, SL, J.Hematother. Stem Cell Res., 10:115-123
• Protection against malignant progression of spontaneously developing liver tumors in transgenic mice expressing O6-mrthylguanine-DNA methyltransferase.  
  Qin, X., Zhang, S., Matsukuma, S., Zarkovic, M., Shimizu, S., Ishikawa, T. and Nakatsuru, Y, Jpn. J. Cancer Res., 91:1085-1089
• Heterozygous DNA mismatch repair gene PMS2 knockout mice are susceptible to intestinal tumor induction with N-methyl-N-nitrosourea.  
  Qin, X., Shibata, D. and Gerson, SL, Carcinogenesis, 21:833-838
• Transgenic expression of human MGMT blocks the hypersensitivity of PMS2-deficient mice to low dose MNU thymic lymphomagenesis.  
  Qin, X., Zhou, H., Liu, L. and Gerson, SL, Carcinogenesis, 20:1667-1673
• Mice defective in the DNA mismatch gene PMS2 are hypersensitive to MNU induced thymic lymphoma and are partially protected by transgenic expression of human MGMT.  
  Qin, X., Liu, L. and Gerson, SL, Oncogene, 18:4394-4400
• Reduced lung tumorigenesis in human MGMT transgenic mice achieved by expression of transgene within the target cell.  
  Liu, L., Qin, X. and Gerson, SL, Carcinogenesis, 20:179-284
• Large motor neuron involvement in Stiff-man syndrome: a qualitative and quantitative study.  
  Ishizawa, K., Komori, T., Okayama, K., Qin, X., Kaneko, K., Sasaki, S. and Iwata, M, Acta Neuropathol (Berl) 97:63-70
• Sick sinus syndrome in association with malignant lymphoma.  
  Suzuki, Y., Ishibashi, S., Qin, X., Oka, T., Ishikawa, T., Nagai, R. and Yazaki, Y, European Heart Journal, 17:968-969
• Detection of ultraviolet photoproducts in mouse skin exposed to natural sunlight by quantitative immunohistochemistry.  
  Qin, X., Zhang, S., Zarkovic, M., Nakatsuru, Y., Shimizu, S., Yamazaki, Y., Nikaido, O., Oda, H. and Ishikawa, T, Jpn. J. Cancer Res., 87:685-690
• Quantitative detection of ultraviolet light-induced photoproducts in mouse skin by immunohistochemistry.  
  Qin, X., Zhang, S., Oda, H., Nakatsuru, Y., Shimizu, S., Yamazaki, Y., Nikaido, O., Oda, H. and Ishikawa, T, Jpn. J. Cancer Res., 86:1041-1048
• Inhibitory effects of probucol on benzo[a]pyrene tumorigenesis.  
  Zarkovic, M., Qin, X., Nakatsuru, Y., Zhang, S., Yamazaki, Y., Oda, H., Ishikawa, T. and Ishikawa, T, Carcinogenesis, 16:2599-2601
• Effect of sophoridine on micronucleus of mouse bone marrow polychromatic erythrocytes.  
  Qin, X., Liu, G., Zheng, Z., Qian, Y. and Yu, Y, J. Chinese Pharmaco. & Toxicol., 4:247
• DNA repair and Carcinogenesis.  
  Ishikawa, T., Qin, X. and Liu, G, J.Henan Oncology, 8:137-159
• Detection of active UV-photoproduct repair in monkey skin in vivo by quantitative immunohistochemitry.  
  Qin, X., Zhang, S., Nakatsuru, Y., Oda, H., Yamazaki, Y., Suzuki, T., Nikaido, O. and Ishikawa, T, Cancer Lett., 83:291-298
• DNA adduct formation and assessment of aberrant crypt foci in vivo in the rat colon mucosa after treatment with N-methyl-N-nitrosourea.  
  Qin, X., Zarkovic, M., Nakatsuru, Y., Arai, M., Oda, H. and Ishikawa, T, Carcinogenesis, 15:851-855
• Tumor promotion by fecapentaene-12 in a rat colon carcinogenesis model.  
  Zarkovic, M., Qin, X., Nakatsuru, Y., Oda, H., Nakamura, T., Shamsuddin, AKM. and Ishikawa, T, Carcinogenesis, 14:1261-1264
• Immunologic detection of in vivo aflatoxin B1-DNA adduct in rats, rainbow trout and coho salmon.  
  Nakatsuru, Y., Qin, X., Prince Masahito and Ishikawa, T, Carcinogenesis, 11:1523-1526
• Species and organ differences in DNA adduct formation and repair after treatment with 4-hydroxyaminoquinoline 1-oxide.  
  Qin, X., Nakatsuru, Y., Tada, M. and Ishikawa, T, Jpn. J. Cancer Res., 81:613-619
• DNA adduct formation and unscheduled DNA synthesis in rat esophagus in vivo after treatment with N-mrthyl-N-nitrosourea.  
  Qin, X., Nakatsuru, Y., Kohyama, K. and Ishikawa, T, Carcinogenesis, 11:235-238
• Effect of flos carthami on micronucleus of mouse bone marrow and human peripheral lymphocyte.  
  Zheng, Z., Dong, W., Liu, G. and Qin, X, J.Henan Oncology, 4:12-15
• The blocking effect of hawthorn extract on the internal synthesis of methylbenzyl-nitrosamine and its carcinogenesis.  
  Liu, Z., Guo, F., Liu, G., Wang, N., Qin, X. and Zheng, X, J.Henan Med. Univ., 26:349-352
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Books/Book Chapters

• The proceeding of the symposium: Cellular and Mulecular Mode of Action of Selected Microbial toxins in foods and Feeds. 
  Chapter: Immunologic detection of aflatoxin B1-DNAadduct in rats and rainbow trout in vivo 
  Page 363 - 367Ishikawa, T., Nakatsuru, Y., Qin, X. and Prince MasahitoPlenum Press, New York
• Gene-Targeting and Interpretation of Disease. 
  Chapter: Gene-Targeting in Cancer Research 
  Page 96 - 105Oda, H., Nakatsuru, Y., Qin, X. and Ishikawa, TEditors: Y. Yazaki.Youdo Press, Tokyo