XiushengQinMDPhD

PubMed

• Towards Understanding the Origin of Cosmic-Ray Electrons.
  Aguilar, M.,Ali Cavasonza, L.,Alpat, B.,Ambrosi, G.,Arruda, L.,Attig, N.,Azzarello, P.,Bachlechner, A.,Barao, F.,Barrau, A.,Barrin, L.,Bartoloni, A.,Basara, L.,Başeğme...> ;Phys. Rev. Lett.. 2019 Apr 02
• Towards Understanding the Origin of Cosmic-Ray Positrons.
  Aguilar, M.,Ali Cavasonza, L.,Ambrosi, G.,Arruda, L.,Attig, N.,Azzarello, P.,Bachlechner, A.,Barao, F.,Barrau, A.,Barrin, L.,Bartoloni, A.,Basara, L.,Başeğmez-du Pree,...> ;Phys. Rev. Lett.. 2019 Feb 16
• Observation of Fine Time Structures in the Cosmic Proton and Helium Fluxes with the Alpha Magnetic Spectrometer on the International Space Station.
  Aguilar, M.,Ali Cavasonza, L.,Alpat, B.,Ambrosi, G.,Arruda, L.,Attig, N.,Aupetit, S.,Azzarello, P.,Bachlechner, A.,Barao, F.,Barrau, A.,Barrin, L.,Bartoloni, A.,Basara...> ;Phys. Rev. Lett.. 2018 Aug 18
• Precision Measurement of Cosmic-Ray Nitrogen and its Primary and Secondary Components with the Alpha Magnetic Spectrometer on the International Space Station.
  Aguilar, M.,Ali Cavasonza, L.,Alpat, B.,Ambrosi, G.,Arruda, L.,Attig, N.,Aupetit, S.,Azzarello, P.,Bachlechner, A.,Barao, F.,Barrau, A.,Barrin, L.,Bartoloni, A.,Basara...> ;Phys. Rev. Lett.. 2018 Aug 18
• Observation of Complex Time Structures in the Cosmic-Ray Electron and Positron Fluxes with the Alpha Magnetic Spectrometer on the International Space Station.
  Aguilar, M.,Cavasonza, L. A.,Ambrosi, G.,Arruda, L.,Attig, N.,Aupetit, S.,Azzarello, P.,Bachlechner, A.,Barao, F.,Barrau, A.,Barrin, L.,Bartoloni, A.,Basara, L.,Başeğm...> ;Phys. Rev. Lett.. 2018 Aug 18
• Observation of the Identical Rigidity Dependence of He, C, and O Cosmic Rays at High Rigidities by the Alpha Magnetic Spectrometer on the International Space Station.
  Aguilar, M.,Ali Cavasonza, L.,Alpat, B.,Ambrosi, G.,Arruda, L.,Attig, N.,Aupetit, S.,Azzarello, P.,Bachlechner, A.,Barao, F.,Barrau, A.,Barrin, L.,Bartoloni, A.,Basara...> ;Phys. Rev. Lett.. 2018 Jan 06
• 39 citations
  DNA repair and cancer: lessons from mutant mouse models.
  Takatoshi Ishikawa, Samuel Shao Min Zhang, Xiusheng Qin, Yoshihisa Takahashi, Hideaki Oda, Yoko Nakatsuru, Fumio Ide> ;Cancer Science. 2004 Feb 1
• 17 citations
  Lung tumorigenesis associated with erb-B-2 and erb-B-3 overexpression in human erb-B-3 transgenic mice is enhanced by methylnitrosourea.
  Hang Zhou, Lili Liu, Keunmyoung Lee, Xiusheng Qin, Adam W. Grasso, Hsing Jien Kung, Joesph E. Willis, Jeffery Kern, Thomas E. Wagner, Stanton L. Gerson> ;Oncogene. 2002 Dec 12
• 19 citations
  MMTV promoter hypomethylation is linked to spontaneous and MNU associated c-neu expression and mammary carcinogenesis in MMTV c-neu transgenic mice.
  Hang Zhou, Wei Dong Chen, Xiusheng Qin, Keunmyoung Lee, Lili Liu, Sanford D. Markowitz, Stanton L. Gerson> ;Oncogene. 2001 Sep 20
• 8 citations
  Differential Degradation Rates of Inactivated Alkyltransferase in Blood Mononuclear Cells and Tumors of Patients after Treatment with O6-Benzylguanine
  Lili Liu, Timothy P. Spiro, Xiusheng Qin, Susan Majka, John R. Haaga, Jane E. Schupp, James K V Willson, Stanton L. Gerson> ;Clinical Cancer Research. 2001 Aug 1
• 13 citations
  Heterozygous DNA mismatch repair gene PMS2-knockout mice are susceptible to intestinal tumor induction with N-methyl-N-nitrosourea.
  Xiusheng Qin, Darryl Shibata, Stanton L. Gerson> ;Carcinogenesis. 2000 Apr 1
• 18 citations
  Transgenic expression of human MGMT blocks the hypersensitivity of PMS2-deficient mice to low dose MNU thymic lymphomagenesis.
  Xiusheng Qin, Hang Zhou, Lili Liu, Stanton L. Gerson> ;Carcinogenesis. 1999 Sep 1
• 32 citations
  Mice defective in the DNA mismatch gene PMS2 are hypersensitive to MNU induced thymic lymphoma and are partially protected by transgenic expression of human MGMT.
  Xiusheng Qin, Lili Liu, Stanton L. Gerson> ;Oncogene. 1999 Jul 29
• 63 citations
  Reduced lung tumorigenesis in human methylguanine DNA-methyltransferase transgenic mice achieved by expression of transgene within the target cell
  Lili Liu, Xiusheng Qin, Stanton L. Gerson> ;Carcinogenesis. 1999 Feb 1
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Journal Articles

• Large motor neuron involvement in Stiff-man syndrome: a qualitative and quantitative study.  
  Ishizawa, K., Komori, T., Okayama, K., Qin, X., Kaneko, K., Sasaki, S. and Iwata, M, Acta Neuropathol (Berl) 97:63-70
• Reduced lung tumorigenesis in human MGMT transgenic mice achieved by expression of transgene within the target cell.  
  Liu, L., Qin, X. and Gerson, SL, Carcinogenesis, 20:179-284
• Mice defective in the DNA mismatch gene PMS2 are hypersensitive to MNU induced thymic lymphoma and are partially protected by transgenic expression of human MGMT.  
  Qin, X., Liu, L. and Gerson, SL, Oncogene, 18:4394-4400
• Transgenic expression of human MGMT blocks the hypersensitivity of PMS2-deficient mice to low dose MNU thymic lymphomagenesis.  
  Qin, X., Zhou, H., Liu, L. and Gerson, SL, Carcinogenesis, 20:1667-1673
• Heterozygous DNA mismatch repair gene PMS2 knockout mice are susceptible to intestinal tumor induction with N-methyl-N-nitrosourea.  
  Qin, X., Shibata, D. and Gerson, SL, Carcinogenesis, 21:833-838
• Protection against malignant progression of spontaneously developing liver tumors in transgenic mice expressing O6-mrthylguanine-DNA methyltransferase.  
  Qin, X., Zhang, S., Matsukuma, S., Zarkovic, M., Shimizu, S., Ishikawa, T. and Nakatsuru, Y, Jpn. J. Cancer Res., 91:1085-1089
• MGMT expression in murine bone marrow is a major determinant of animal survival after alkylating agent exposure.  
  Reese, JS., Qin, X., Ballas, CB., Sekiguchi, M. and Gerson, SL, J.Hematother. Stem Cell Res., 10:115-123
• Importance of DNA repair in carcinogenesis: evidence from transgenic and gene targeting studies.  
  Ishikawa, T., Ide, F., Qin, X., Takahashi, Y., Sekiguchi, M., Tanaka, K. and Nakatsuru, Y, Mutat. Res., 2:477:41-49
• Differential degradation rates of inactivated alkyltransferase in blood mononuclear cells and tumors of patients after treatment with O(6)-benzylguanine.  
  Liu, L., Spiro, TP., Qin, X., Majka, S., Haaga, J., Schupp, J., Willson, JK., Gerson, SL, Clin Cancer Res., 7: 2318-2324
• MMTV promoter hypomethylation is linked to spontaneous and MNU associated c-neu expression and mammary carcinogenesis in MMTV c-neu transgenic mice.  
  Zhou, H., Chen, W.D., Qin, X., Lee, K., Liu, L., Markowitz, S.D. and Gerson, S.L, Oncogene, 20: 6009-6017
• Effect of sophoridine on micronucleus of mouse bone marrow polychromatic erythrocytes.  
  Qin, X., Liu, G., Zheng, Z., Qian, Y. and Yu, Y, J. Chinese Pharmaco. & Toxicol., 4:247
• Study on the induction of esophageal epithelial cancer of cultured human embryo cells by alternariol.  
  Liu, G., Qian, Y., Yang, H., Gong, Y., Dong, Z., Zhang, P., Qin, X., Zhao, L., Chen, Z. and Ma, C, J.Henan Med. Univ., 25: 115-118
• Preliminary investigation of mutagenicity of sophoridine.  
  Qin, X., Liu, G., Zheng, Z., Qian, Y., Ruan, L., Su, T., Xu, Y., Li, X. and Yu, Y, J.Henan Med. Univ., 25: 225
• Studies on the mutagenicity of sophoridine.  
  Qin, X., Liu, G., Zheng, Z., Qian, Y., Ruan, L., Su, T., Xu, Y., Li, X. and Yu, Y, J.Henan Oncology, 4:5-7
• Mutagenicity detection of the extract of flos carthami.  
  Zheng, Z., Dong, W., Liu, G. and Qin, X, Carcinogenesis-Teratogenesis-Mutation, 3:74-75
• Studies on binding between alternariol and human fatal esophagus DNA and identification of the type of binding.  
  Hao, H., Zhang, P., Dong, Z., Liu, G., Qin, X., Zhen, Y. and Miao, J, Cancer (Chinese), 10:371-374
• The blocking effect of hawthorn extract on the internal synthesis of methylbenzyl-nitrosamine and its carcinogenesis.  
  Liu, Z., Guo, F., Liu, G., Wang, N., Qin, X. and Zheng, X, J.Henan Med. Univ., 26:349-352
• Effect of flos carthami on micronucleus of mouse bone marrow and human peripheral lymphocyte.  
  Zheng, Z., Dong, W., Liu, G. and Qin, X, J.Henan Oncology, 4:12-15
• DNA adduct formation and unscheduled DNA synthesis in rat esophagus in vivo after treatment with N-mrthyl-N-nitrosourea.  
  Qin, X., Nakatsuru, Y., Kohyama, K. and Ishikawa, T, Carcinogenesis, 11:235-238
• Species and organ differences in DNA adduct formation and repair after treatment with 4-hydroxyaminoquinoline 1-oxide.  
  Qin, X., Nakatsuru, Y., Tada, M. and Ishikawa, T, Jpn. J. Cancer Res., 81:613-619
• Immunologic detection of in vivo aflatoxin B1-DNA adduct in rats, rainbow trout and coho salmon.  
  Nakatsuru, Y., Qin, X., Prince Masahito and Ishikawa, T, Carcinogenesis, 11:1523-1526
• Tumor promotion by fecapentaene-12 in a rat colon carcinogenesis model.  
  Zarkovic, M., Qin, X., Nakatsuru, Y., Oda, H., Nakamura, T., Shamsuddin, AKM. and Ishikawa, T, Carcinogenesis, 14:1261-1264
• DNA adduct formation and assessment of aberrant crypt foci in vivo in the rat colon mucosa after treatment with N-methyl-N-nitrosourea.  
  Qin, X., Zarkovic, M., Nakatsuru, Y., Arai, M., Oda, H. and Ishikawa, T, Carcinogenesis, 15:851-855
• Detection of active UV-photoproduct repair in monkey skin in vivo by quantitative immunohistochemitry.  
  Qin, X., Zhang, S., Nakatsuru, Y., Oda, H., Yamazaki, Y., Suzuki, T., Nikaido, O. and Ishikawa, T, Cancer Lett., 83:291-298
• DNA repair and Carcinogenesis.  
  Ishikawa, T., Qin, X. and Liu, G, J.Henan Oncology, 8:137-159
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Books/Book Chapters

• The proceeding of the symposium: Cellular and Mulecular Mode of Action of Selected Microbial toxins in foods and Feeds. 
  Chapter: Immunologic detection of aflatoxin B1-DNAadduct in rats and rainbow trout in vivo 
  Page 363 - 367Ishikawa, T., Nakatsuru, Y., Qin, X. and Prince MasahitoPlenum Press, New York
• Gene-Targeting and Interpretation of Disease. 
  Chapter: Gene-Targeting in Cancer Research 
  Page 96 - 105Oda, H., Nakatsuru, Y., Qin, X. and Ishikawa, TEditors: Y. Yazaki.Youdo Press, Tokyo