Yanis Boumber MD PhD

PubMed

• HER2 alterations across solid tumors: implications for comprehensive testing.
  Ahmed Ismail, Chimay Jani, Nusrat Jahan, Malla Midhun, Arnab Basu
  The Oncologist. 2025-09-01
• Safe Treatment of an Extensive-Stage Small-Cell Lung Cancer With Tarlatamab in an Orthotopic Heart Transplantation Patient: A Case Report.
  Amr Ismail, Tingting Zhang, Aaron Vickers, Drexell H Boggs, Aakash Desai
  Cureus. 2025-09-01
• DISCERN: A Randomized Pilot Study Comparing Dual Versus Single Immune Checkpoint Blockade Plus Chemotherapy in PD-L1 Negative Advanced Non-Small Cell Lung Cancer.
  Aakash Desai, Ellen McNeeley, Sanad Alhushki, Mia Haught, Juan Xavier Masjoan Juncos
  Clinical Lung Cancer. 2025-08-26

Journal Articles

• Epigenetic inactivation of notch-hes pathway in human B-cell acute lymphoblastic leukemia  
  Kuang SQ, Fang Z, Zweidler-McKay PA, Yang H, Wei Y, Gonzalez-Cervantes EA, Boumber Y, Garcia-Manero G, PLoS One, 4/1/2013
• Final Report of a Randomized Study of Decitabine Versus Conventional Care for Maintenance Therapy in Patients with Intermediate and High Risk Acute Myeloid Leukemia in...  
  Boumber Y, Kantarjian H, Jorgensen J, Faderl S, Castoro R, Autry J, Garcia-Manero G, Borthakur G, Jabbour E, Estrov Z, Cortes J, Issa JP, Ravandi F, Leukemia, 11/1/2012
• Mocetinostat (MGCD0103): a review of an isotype-specific histone deacetylase inhibitor  
  Boumber Y, Younes A, Garcia-Manero G, Expert Opinion in Investigational Drugs, 6/1/2011
• Epigenetics-what's the future?  
  Boumber Y and Issa, JP, Oncology, 3/1/2011
• DNA methylation profiles of primary colorectal carcinoma and matched liver metastasis  
  Konishi K, Watanabe Y, Shen L, Guo Y, Castoro RJ, Kondo K, Chung W, Ahmed S, Jelinek J, Boumber YA, Estecio MR, Maegawa S, Kondo Y, Itoh F, Imawari M, Hamilton SR, Iss..., PLoS One, 1/1/2011
• Chromatin remodeling is required for gene reactivation after 5-aza-2'-deoxycytidine mediated DNA hypomethylation  
  Si J, Boumber YA, Shu J, Qin T, Ahmed S, He R, Jelinek J, Issa JP, Cancer Research, 9/1/2010
• An Sp1/Sp3 binding polymorphism confers methylation protection  
  Boumber YA, Kondo Y, Chen X, Shen L, Guo Y, Tellez C, Estecio MR, Ahmed S, Issa JP, PLoS Genetics, 8/22/2008
• Gene silencing in cancer by histone H3 lysine 27 tri-methylation independent of promoter DNA methylation  
  Kondo Y, Shen L, Cheng AS, Ahmed S, Boumber Y, Charo C, Yamochi T, Urano T, Furukawa K, Kwabi-Addo B, Gold DL, Sekido Y, Huang TH, Issa JP, Nature Genetics, 6/1/2008
• Downregulation of histone H3 lysine 9 methyltransferase G9a induces centrosome disruption and chromosome instability in cancer cells  
  Kondo Y, Shen L, Ahmed S, Boumber Y, Sekido Y, Haddad BR, Issa JP, PLoS ONE, 4/1/2008
• Drug sensitivity prediction by CpG island methylation profile in the NCI-60 cancer cell line panel  
  Shen L, Kondo Y, Ahmed S, Boumber Y, Konishi K, Guo Y, Chen X, Vilaythong JN, Issa JP, Cancer Research, 12/1/2007
• RIL, a LIM gene on 5q31, is silenced by methylation in cancer and sensitizes cancer cells to apoptosis  
  Boumber YA, Kondo Y, Chen X, Shen L, Gharibyan V, Konishi K, Estey E, Kantarjian H, Garcia-Manero G and Issa JP, Cancer Research, 3/1/2007
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Books/Book Chapters

• Emerging Cancer Therapeutics: Leukemia 
  Chapter: The Myelodysplastic Syndromes. 
  Boumber Y, Garcia-Manero G2011

Lectures

• "Collaborative Translational Research Meeting" 
  Princess Margaret Cancer Centre, Toronto - 1/1/2013
• "Cancer Epigenetics" 
  Boston, MA - 1/1/2008
• Annual Symposium: "Stem Cells and Regenerative Medicine" 
  Houston, TX - 1/1/2006
• "Pathology of the 21st Century Conference" 
  Houston, TX - 1/1/2006
• "Abcam Chromatin Structure & Function Meeting" 
  Cancun, Mexico - 1/1/2004
• "Annual UT Health Science Center Research Forum" 
  Houston, TX - 1/1/2003
• "Annual European Cytogenetics Conference" 
  Vienna, Austria - 1/1/1999
• "Modern Cytogenetic and Morphological Methods: from Science to Practice" 
  Rostov-on-Don, Russia - 1/1/1998
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