YanisBoumberMDPhD

PubMed

• PIP4K2B Protein Regulation by NSD1 in HPV-Negative Head and Neck Squamous Cell Carcinoma.
  Iuliia Topchu, Igor Bychkov, Petr Makhov, Ekaterina Roshchina, Yanis Boumber> ;Cancers. 2024 Mar 17
• 1 citations
  NSD1 supports cell growth and regulates autophagy in HPV-negative head and neck squamous cell carcinoma.
  Iuliia Topchu, Igor Bychkov, Demirkan Gursel, Petr Makhov, Yanis Boumber> ;Cell Death Discovery. 2024 Feb 13
• NSD1 supports cell growth and regulates autophagy in HPV-negative head and neck squamous cell carcinoma.
  Iuliia Topchu, Igor Bychkov, Demirkan Gursel, Petr Makhov, Yanis Boumber> ;Biorxiv. 2023 Sep 22
• Regulation of VEGFR2 and AKT Signaling by Musashi-2 in Lung Cancer.
  Igor Bychkov, Iuliia Topchu, Petr Makhov, Alexander Kudinov, Jyoti D Patel, Yanis Boumber> ;Cancers. 2023 Apr 28
• 2 citations
  Regulation of VEGFR2 and AKT signaling by Musashi-2 in lung cancer.
  Igor Bychkov, Iuliia Topchu, Petr Makhov, Alexander Kudinov, Jyoti D Patel, Yanis Boumber> ;Biorxiv. 2023 Mar 31
• 3 citations
  Rationally designed inhibitors of the Musashi protein-RNA interaction by hotspot mimicry.
  Nan Bai, Yusuf Adeshina, Igor Bychkov, Yan Xia, Ragul Gowthaman, Sven A Miller, Abhishek K Gupta, David K Johnson, Lan Lan, Erica A Golemis, Petr B Makhov, Liang Xu, M...> ;Biorxiv. 2023 Jan 10
• 1 citations
  Rationally designed inhibitors of the Musashi protein-RNA interaction by hotspot mimicry.
  Nan Bai, Yusuf Adeshina, Igor Bychkov, Yan Xia, Ragul Gowthaman, Sven A Miller, Abhishek K Gupta, David K Johnson, Lan Lan, Erica A Golemis, Petr B Makhov, Liang Xu, M...> ;Research Square. 2023 Jan 10
• 3 citations
  The Prognostic and Therapeutic Potential of DNA Damage Repair Pathway Alterations and Homologous Recombination Deficiency in Lung Cancer.
  Karam Khaddour, Manuel Felipe Fernandez, Marsel Khabibov, Airat Garifullin, Danielle Dressler, Iuliia Topchu, Jyoti D Patel, Frank Weinberg, Yanis Boumber> ;Cancers. 2022 Oct 28
• 23 citations
  Signaling pathways and therapeutic approaches in glioblastoma multiforme (Review).
  Marsel Khabibov, Airat Garifullin, Yanis Boumber, Karam Khaddour, Manuel Fernandez, Firat Khamitov, Larisa Khalikova, Natalia Kuznetsova, Oleg Kit, Leonid Kharin> ;International Journal of Oncology. 2022 Jun 1
• 15 citations
  The role of NSD1, NSD2, and NSD3 histone methyltransferases in solid tumors.
  Iuliia Topchu, Rajendra P Pangeni, Igor Bychkov, Sven A Miller, Evgeny Izumchenko, Jindan Yu, Erica Golemis, John Karanicolas, Yanis Boumber> ;Cellular and Molecular Life Sciences. 2022 May 9
• 5 citations
  Prognostic role and biologic features of Musashi-2 expression in colon polyps and during colorectal cancer progression.
  Leonid V. Kharin, Igor Bychkov, Nikolay S. Karnaukhov, Mark Voloshin, Rushaniya Fazliyeva, Alexander Y. Deneka, Elena M. Frantsiyants, Oleg I. Kit, Erica A. Golemis, Y...> ;Plos One. 2021 Jul 8
• 29 citations
  Targeting the Epidermal Growth Factor Receptor in EGFR-Mutated Lung Cancer: Current and Emerging Therapies.
  Karam Khaddour, Sushma Jonna, Alexander Y. Deneka, Jyoti D. Patel, Mohamed E. Abazeed, Erica A. Golemis, Hossein Borghaei, Yanis Boumber> ;Cancers. 2021 Jun 24
• 16 citations
  Musashi-2 (MSI2) regulates epidermal growth factor receptor (EGFR) expression and response to EGFR inhibitors in EGFR-mutated non-small cell lung cancer (NSCLC).
  Petr Makhov, Igor Bychkov, Bulat Faezov, Alexander Y. Deneka, Alexander E. Kudinov, Emmanuelle Nicolas, Rohan Brebion, Eleanor Avril, Kathy Q. Cai, Leonid V. Kharin, M...> ;Oncogenesis. 2021 Mar 15
• 5 citations
  Musashi 2 (MSI2) expression as an independent prognostic biomarker in non-small cell lung cancer (NSCLC).
  Iuliia Topchu, Nikolai Karnaukhov, Alexandra Mazitova, Veronika Yugai, Mark Voloshin, Mariya Tikhomirova, Oleg I. Kit, Elena M. Frantsiyants, Leonid V. Kharin, Tamara ...> ;Journal of Thoracic Disease. 2021 Mar 1
• 7 citations
  Design, synthesis and biological evaluation of 2-quinolyl-1,3-tropolone derivatives as new anti-cancer agents.
  Evgeniy A. Gusakov, Iuliia Topchu, Aleksandra M. Mazitova, Igor V. Dorogan, Emil Bulatov, Ilya G. Serebriiskii, Zinaida I. Abramova, I. O. Tupaeva, Oleg P. Demidov, Du...> ;RSC Advances. 2021 Jan 21
• 16 citations
  Obesity, Sarcopenia, and Outcomes in Non-Small Cell Lung Cancer Patients Treated With Immune Checkpoint Inhibitors and Tyrosine Kinase Inhibitors.
  Karam Khaddour, Sandra L. Gomez-Perez, Nikita Jain, Jyoti D. Patel, Yanis Boumber> ;Frontiers in Oncology. 2020 Oct 20
• 11 citations
  CRISPR/Cas9 genome-wide loss-of-function screening identifies druggable cellular factors involved in sunitinib resistance in renal cell carcinoma.
  Peter Makhov, Ji A. Sohn, Ilya G. Serebriiskii, Rushaniya Fazliyeva, Vladimir Khazak, Yanis Boumber, Robert G. Uzzo, Vladimir Kolenko> ;British Journal of Cancer. 2020 Sep 24
• 173 citations
  Biomarkers for immune checkpoint inhibition in non–small cell lung cancer (NSCLC)
  J. Nicholas Bodor, Yanis Boumber, Hossein Borghaei> ;Cancer. 2020 Jan 15
• 17 citations
  Tumor-Targeted Drug Conjugates as an Emerging Novel Therapeutic Approach in Small Cell Lung Cancer (SCLC).
  Alexander Y. Deneka, Yanis Boumber, Tim N. Beck, Erica A. Golemis> ;Cancers. 2019 Sep 3
• 123 citations
  Existing and Emerging Biomarkers for Immune Checkpoint Immunotherapy in Solid Tumors
  Sanjeevani Arora, Rodion Velichinskii, Randy W. Lesh, Usman Ali, Michal Kubiak, Pranshu Bansal, Hossein Borghaei, Martin J. Edelman, Yanis Boumber> ;Advances in Therapy. 2019 Aug 13
• 2 citations
  An improved method of delivering a sclerosing agent for the treatment of malignant pleural effusion
  Tim N. Beck, Alexander Y. Deneka, Louis F. Chai, Colin Joseph Kanach, Priya Johal, Nicolas J. Alvarez, Yanis Boumber, Erica A. Golemis, Glenn W. Laub> ;BMC Cancer. 2019 Jun 24
• 26 citations
  Circulating tumor cell and cell-free RNA capture and expression analysis identify platelet-associated genes in metastatic lung cancer
  Tim N. Beck, Yanis Boumber, Charu Aggarwal, Jianming Pei, Catherine A. Thrash-Bingham, Patricia Fittipaldi, Ramillya Vlasenkova, Chandra Rao, Hossein Borghaei, Massimo...> ;BMC Cancer. 2019 Jun 19
• 12 citations
  Case report: reinitiating pembrolizumab treatment after small bowel perforation
  Tim N. Beck, Alexander E. Kudinov, Essel Dulaimi, Yanis Boumber> ;BMC Cancer. 2019 Apr 24
• 183 citations
  NCCN guidelines® insights: Small cell lung cancer, version 2.2018 featured updates to the NCCN guidelines
  Gregory P. Kalemkerian, Billy W. Loo, Wallace Akerley, Albert Attia, Michael F. Bassetti, Yanis Boumber, Roy H. Decker, M. Chris Dobelbower, Afshin Dowlati, Robert J. ...> ;Journal of the National Comprehensive Cancer Network. 2018 Oct 1
• 50 citations
  Tumor mutational burden (TMB) as a biomarker of response to immunotherapy in small cell lung cancer.
  Yanis Boumber> ;Journal of Thoracic Disease. 2018 Aug 1
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Journal Articles

• Epigenetic inactivation of notch-hes pathway in human B-cell acute lymphoblastic leukemia  
  Kuang SQ, Fang Z, Zweidler-McKay PA, Yang H, Wei Y, Gonzalez-Cervantes EA, Boumber Y, Garcia-Manero G, PLoS One, 4/1/2013
• Final Report of a Randomized Study of Decitabine Versus Conventional Care for Maintenance Therapy in Patients with Intermediate and High Risk Acute Myeloid Leukemia in...  
  Boumber Y, Kantarjian H, Jorgensen J, Faderl S, Castoro R, Autry J, Garcia-Manero G, Borthakur G, Jabbour E, Estrov Z, Cortes J, Issa JP, Ravandi F, Leukemia, 11/1/2012
• Mocetinostat (MGCD0103): a review of an isotype-specific histone deacetylase inhibitor  
  Boumber Y, Younes A, Garcia-Manero G, Expert Opinion in Investigational Drugs, 6/1/2011
• Epigenetics-what's the future?  
  Boumber Y and Issa, JP, Oncology, 3/1/2011
• DNA methylation profiles of primary colorectal carcinoma and matched liver metastasis  
  Konishi K, Watanabe Y, Shen L, Guo Y, Castoro RJ, Kondo K, Chung W, Ahmed S, Jelinek J, Boumber YA, Estecio MR, Maegawa S, Kondo Y, Itoh F, Imawari M, Hamilton SR, Iss..., PLoS One, 1/1/2011
• Chromatin remodeling is required for gene reactivation after 5-aza-2'-deoxycytidine mediated DNA hypomethylation  
  Si J, Boumber YA, Shu J, Qin T, Ahmed S, He R, Jelinek J, Issa JP, Cancer Research, 9/1/2010
• An Sp1/Sp3 binding polymorphism confers methylation protection  
  Boumber YA, Kondo Y, Chen X, Shen L, Guo Y, Tellez C, Estecio MR, Ahmed S, Issa JP, PLoS Genetics, 8/22/2008
• Gene silencing in cancer by histone H3 lysine 27 tri-methylation independent of promoter DNA methylation  
  Kondo Y, Shen L, Cheng AS, Ahmed S, Boumber Y, Charo C, Yamochi T, Urano T, Furukawa K, Kwabi-Addo B, Gold DL, Sekido Y, Huang TH, Issa JP, Nature Genetics, 6/1/2008
• Downregulation of histone H3 lysine 9 methyltransferase G9a induces centrosome disruption and chromosome instability in cancer cells  
  Kondo Y, Shen L, Ahmed S, Boumber Y, Sekido Y, Haddad BR, Issa JP, PLoS ONE, 4/1/2008
• Drug sensitivity prediction by CpG island methylation profile in the NCI-60 cancer cell line panel  
  Shen L, Kondo Y, Ahmed S, Boumber Y, Konishi K, Guo Y, Chen X, Vilaythong JN, Issa JP, Cancer Research, 12/1/2007
• RIL, a LIM gene on 5q31, is silenced by methylation in cancer and sensitizes cancer cells to apoptosis  
  Boumber YA, Kondo Y, Chen X, Shen L, Gharibyan V, Konishi K, Estey E, Kantarjian H, Garcia-Manero G and Issa JP, Cancer Research, 3/1/2007
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Books/Book Chapters

• Emerging Cancer Therapeutics: Leukemia 
  Chapter: The Myelodysplastic Syndromes. 
  Boumber Y, Garcia-Manero G2011

Lectures

• "Collaborative Translational Research Meeting" 
  Princess Margaret Cancer Centre, Toronto - 1/1/2013
• "Cancer Epigenetics" 
  Boston, MA - 1/1/2008
• Annual Symposium: "Stem Cells and Regenerative Medicine" 
  Houston, TX - 1/1/2006
• "Pathology of the 21st Century Conference" 
  Houston, TX - 1/1/2006
• "Abcam Chromatin Structure & Function Meeting" 
  Cancun, Mexico - 1/1/2004
• "Annual UT Health Science Center Research Forum" 
  Houston, TX - 1/1/2003
• "Annual European Cytogenetics Conference" 
  Vienna, Austria - 1/1/1999
• "Modern Cytogenetic and Morphological Methods: from Science to Practice" 
  Rostov-on-Don, Russia - 1/1/1998
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