YazanAlsayedMD

PubMed

• 82 citations
  Improvement in long-term outcomes with successive Total Therapy trials for multiple myeloma: are patients now being cured?
  Saad Z. Usmani, John Crowley, Antje Hoering, Alan Mitchell, Sarah Waheed, Bijay Nair, Yazan Alsayed, F vanRhee, Bart Barlogie> ;Leukemia. 2013 Jan 1
• 254 citations
  Extramedullary disease portends poor prognosis in multiple myeloma and is over-represented in high-risk disease even in the era of novel agents
  Saad Z. Usmani, Christoph Heuck, Alan Mitchell, Jackie Szymonifka, Bijay Nair, Antje Hoering, Yazan Alsayed, Sarah Waheed, Sajjad Haider, Alejandro Restrepo, Frits van...> ;Haematologica. 2012 Nov 1
• 16 citations
  Thalidomide in Total Therapy 2 Overcomes Inferior Prognosis of Myeloma with Low Expression of the Glucocorticoid Receptor Gene NR3C1
  Christoph Heuck, Jackie Szymonifka, Emily Hansen, John D. Shaughnessy, Saad Z. Usmani, Frits van Rhee, Elias Anaissie, Bijay Nair, Sarah Waheed, Yazan Alsayed, Nathan ...> ;Clinical Cancer Research. 2012 Oct 1
• 55 citations
  Primary plasma cell leukemia: clinical and laboratory presentation, gene-expression profiling, and clinical outcome with Total Therapy protocols
  Saad Z. Usmani, Bijay Nair, Pingping Qu, Emily Hansen, Qing Zhang, Nathan Petty, Sarah Waheed, John D. Shaughnessy, Yazan Alsayed, Christoph Heuck, F. van Rhee, Teresa...> ;Leukemia. 2012 Apr 17
• 129 citations
  Pharmacogenomics of bortezomib test-dosing identifies hyperexpression of proteasome genes, especially PSMD4, as novel high-risk feature in myeloma treated with Total T...
  John D. Shaughnessy, Pingping Qu, Saad Z. Usmani, Christoph Heuck, Qing Zhang, Yiming Zhou, Erming Tian, Ichiro Hanamura, Frits van Rhee, Elias Anaissie, Joshua Epstei...> ;Blood. 2011 Sep 29
• Extramedullary disease (EMD): A common terminal pathway in multiple myeloma (MM) progression.
  Usmani SZ, Mitchell A, Szymonifka J, Shaughnessy JD, Hoering A, Alsayed Y, Waheed S, Nair B, Crowley J, Barlogie B> ;J. Clin. Oncol.. 2011-05-20
• Phase II study of carfilzomib (CFZ) in combination with current agents for relapsed and refractory multiple myeloma (RRMM).
  Szymonifka J, Usmani SZ, Sexton R, Panozzo S, Nair BP, Waheed S, Alsayed Y, Crowley J, Barlogie B> ;J. Clin. Oncol.. 2011-05-20
• 27 citations
  International staging system and metaphase cytogenetic abnormalities in the era of gene expression profiling data in multiple myeloma treated with total therapy 2 and ...
  Sarah Waheed, John D. Shaughnessy, Frits van Rhee, Yazan Alsayed, Bijay Nair, Elias Anaissie, Jackie Szymonifka, Antje Hoering, John Crowley, Bart Barlogie> ;Cancer. 2011 Mar 1
• 90 citations
  Total Therapy 3 for multiple myeloma: prognostic implications of cumulative dosing and premature discontinuation of VTD maintenance components, bortezomib, thalidomide...
  Frits van Rhee, Jackie Szymonifka, Elias Anaissie, Bijay Nair, Sarah Waheed, Yazan Alsayed, Nathan Petty, John D. Shaughnessy, Antje Hoering, John Crowley, Bart Barlogie> ;Blood. 2010 Aug 26
• 161 citations
  Superior results of Total Therapy 3 (2003-33) in gene expression profiling-defined low-risk multiple myeloma confirmed in subsequent trial 2006-66 with VRD maintenance.
  Bijay Nair, Frits van Rhee, John D. Shaughnessy, Elias Anaissie, Jackie Szymonifka, Antje Hoering, Yazan Alsayed, Sarah Waheed, John Crowley, Bart Barlogie> ;Blood. 2010 May 27
• 144 citations
  High-risk myeloma is associated with global elevation of miRNAs and overexpression of EIF2C2/AGO2.
  Yiming Zhou, Lijuan Chen, Bart Barlogie, Owen W. Stephens, Xiaosong Wu, David R. Williams, Marie-Astrid Cartron, Frits van Rhee, Bijay Nair, Sarah Waheed, Mauricio Pin...> ;Proceedings of the National Academy of Sciences of the United States of America. 2010 Apr 27
• 60 citations
  TP53 deletion is not an adverse feature in multiple myeloma treated with total therapy 3.
  John D. Shaughnessy, Yiming Zhou, Jeffrey Haessler, Frits van Rhee, Elias Anaissie, Bijay Nair, Sarah Waheed, Yazan Alsayed, Joshua Epstein, John Crowley, Bart Barlogie> ;British Journal of Haematology. 2009 Nov 1
• 82 citations
  Complete remission in multiple myeloma examined as time-dependent variable in terms of both onset and duration in Total Therapy protocols
  Antje Hoering, John Crowley, John D. Shaughnessy, Klaus Hollmig, Yazan Alsayed, Jackie Szymonifka, Sarah Waheed, Bijay Nair, Frits van Rhee, Elias Anaissie, Bart Barlogie> ;Blood. 2009 Aug 13
• 19 citations
  Gene expression profiling of plasma cells at myeloma relapse from tandem transplantation trial Total Therapy 2 predicts subsequent survival
  Bijay Nair, John D. Shaughnessy, Yiming Zhou, Marie Astrid-Cartron, Pingping Qu, Frits van Rhee, Elias Anaissie, Yazan Alsayed, Sarah Waheed, Klaus Hollmig, Jackie Szy...> ;Blood. 2009 Jun 25
• Gene expression profiling (GEP) of cd 138-purified plasma cells (pc) in previously treated multiple myeloma (PTMM): Validating prognostic models developed in newly dia...
  Alsayed Y, Haessler J, Barlogie B, Crowley J, Shaughnessy J> ;J. Clin. Oncol.. 2009-05-20
• Gene expression profiling (GEP)-defined risk and molecular subgroups assessed at baseline and at relapse: Collective impact on post-relapse survival of multiple myelom...
  Nair B, Shaughnessy J, Alsayed Y, Haessler J, van Rhee F, Hollmig K, Pineda-Roman M, Crowley J, Barlogie B> ;J. Clin. Oncol.. 2009-05-20
• MDS-associated cytogenetic abnormalities (MDS-CA) after total therapy (TT) regimens for newly diagnosed multiple myeloma (MM): Apparent surge after introduction of pos...
  Hollmig K, Waheed S, Nair B, Haessler J, Petty N, Pineda-Roman M, Alsayed Y, van Rhee F, Crowley J, Barlogie B> ;J. Clin. Oncol.. 2009-05-20
• Plerixafor (P) plus G-CSF (G) in previous peripheral blood progenitor cell (HPC) mobilization failures (MF).
  Van Rhee F, Panozzo S, Anaissie E, Pineda-Roman M, Waheed S, Alsayed Y, Nair B, Cottler-Fox M, Barlogie B> ;J. Clin. Oncol.. 2009-05-20
• 181 citations
  Thalidomide arm of Total Therapy 2 improves complete remission duration and survival in myeloma patients with metaphase cytogenetic abnormalities.
  Bart Barlogie, Mauricio Pineda-Roman, Frits van Rhee, Jeff Haessler, Elias Anaissie, Klaus Hollmig, Yazan Alsayed, Sarah Waheed, Nathan Petty, Joshua Epstein, John D. ...> ;Blood. 2008 Oct 15
• 82 citations
  Seven-year median time to progression with thalidomide for smoldering myeloma: partial response identifies subset requiring earlier salvage therapy for symptomatic dis...
  Bart Barlogie, Frits van Rhee, John D. Shaughnessy, Joshua Epstein, Shmuel Yaccoby, Mauricio Pineda-Roman, Klaus Hollmig, Yazan Alsayed, Antje Hoering, Jackie Szymonif...> ;Blood. 2008 Oct 15
• 19 citations
  Proteomics analysis in post-transplant lymphoproliferative disorders
  Yazan Alsayed, Xavier Leleu, Alexey A. Leontovich, Ana B. Oton, Mona F. Melhem, Diane George, Irene M. Ghobrial> ;European Journal of Haematology. 2008 Oct 1
• 99 citations
  Complete remission sustained 3 years from treatment initiation is a powerful surrogate for extended survival in multiple myeloma
  Bart Barlogie, Elias Anaissie, Jeff Haessler, Fritz Van Rhee, Mauricio Pineda-Roman, Klaus Hollmig, Yazan Alsayed, Joshua Epstein, John D. Shaughnessy, John Crowley> ;Cancer. 2008 Jul 15
• Randomized, dose-defined, phase 1B study of recombinant human mannose-binding lectin (rhMBL, EZN-2232) in patients with multiple myeloma undergoing high-dose chemother...
  Anaissie EJ, Pineda-Roman M, Van Rhee F, Waheed S, Kiwan E, Alsayed Y, Kalambakas S, Buchbinder A, Barlogie B> ;J. Clin. Oncol.. 2008-05-20
• 42 citations
  Targeting Akt and Heat Shock Protein 90 Produces Synergistic Multiple Myeloma Cell Cytotoxicity in the Bone Marrow Microenvironment
  Alissa Huston, Xavier Leleu, Xiaoying Jia, Anne Moreau, Hai T. Ngo, Judith Runnels, Judy Anderson, Yazan Alsayed, Aldo M. Roccaro, Sonia Vallet, Evdoxia Hatjiharissi, ...> ;Clinical Cancer Research. 2008 Feb 1
• 58 citations
  Cytogenetically defined myelodysplasia after melphalan-based autotransplantation for multiple myeloma linked to poor hematopoietic stem-cell mobilization: the Arkansas...
  Bart Barlogie, Guido Tricot, Jeff Haessler, Frits van Rhee, Michele Cottler-Fox, Elias Anaissie, James Waldron, Mauricio Pineda-Roman, Raymond Thertulien, Maurizio Zan...> ;Blood. 2008 Jan 1
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